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The map label for this gene is coaX [H]

Identifier: 41406556

GI number: 41406556

Start: 485117

End: 485932

Strand: Direct

Name: coaX [H]

Synonym: MAP0458

Alternate gene names: 41406556

Gene position: 485117-485932 (Clockwise)

Preceding gene: 41406555

Following gene: 41406557

Centisome position: 10.04

GC content: 69.24

Gene sequence:

>816_bases
GTGCTGCTGGCCATCGACGTCCGTAACACCCACACCGTCGTCGGGCTGATATCCGGCTCCAAAGAGCACGCAAAAGTGGT
GCAGCAGTGGCGGATTCGCACCGAGTCGGAGATCACCGCCGACGAGCTGGCGCTGACCATCGACGGTTTGATCGGCGACG
ACTCGGAGCGGCTCACCGGCGCCGCCGCGCTGTCGACCGTGCCGTCGGTGCTGCACGAGGTGCGCCTCATGCTCGACCAG
TACTGGCCGTCGGTGCCGCACGTGCTGATCGAGCCCGGGGTGCGCACCGGCATCCCGCTGCTGGTGGACAACCCCAAGGA
AGTGGGCGCCGACCGGATCGTCAACTGCCTGGCCGCTTTTCACCGTTTCCAAAGCCCCGCCATCGTCATCGACTTCGGAT
CCTCGATCTGCGTGGACGTCGTGTCGGCCAAGGGCGAATTCCTGGGCGGCGCGATCGCGCCCGGACTGCAGGTCTCCTCC
GATGCCGCCGCGGCCCGCTCCGCCGCGCTGCGCCGGGTCGAGCTGGCCCGCCCCCGCTCGGTGATCGGCAAGAACACCGT
CGAATGCATGCAGGCGGGCGCAGTGTTCGGCTTCGCCGGGCTGGTCGACGGCCTGGTCGGGCGCATCCGCGAGGACGTGC
CGGGATTCGGCGGCGACGACGTCGCGATTGTGGCCACCGGGCACACCGCGCCGCTGCTGCTGCCCGAACTGGACACCGTC
AGCCACTACGACCAGCACCTGACCCTGCACGGCCTGCGGCTGGTTTTCGAACGCAACCGGGATGCGCAGCGCGGGCGGCT
GAAAACGGCCCGGTGA

Upstream 100 bases:

>100_bases
ACAAGCCGGTCGACCTCGGCCACGATCCGGCATTCGTGCCGGACTTCGAGATAGCAGGGGCGGCCGAGCTGCTCGATCCC
CGGATCGTTGCGCGGTAGCC

Downstream 100 bases:

>100_bases
CGGCGTCGGGCGCGGCCTGGCGGCCGCGTCATTTAAGCTGGCACGTCGTGAGTCCCGCCCCAGACGCCGACATTCCCGAG
CAGTACCGGATCCGCCGGGA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLLAIDVRNTHTVVGLISGSKEHAKVVQQWRIRTESEITADELALTIDGLIGDDSERLTGAAALSTVPSVLHEVRLMLDQ
YWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAFHRFQSPAIVIDFGSSICVDVVSAKGEFLGGAIAPGLQVSS
DAAAARSAALRRVELARPRSVIGKNTVECMQAGAVFGFAGLVDGLVGRIREDVPGFGGDDVAIVATGHTAPLLLPELDTV
SHYDQHLTLHGLRLVFERNRDAQRGRLKTAR

Sequences:

>Translated_271_residues
MLLAIDVRNTHTVVGLISGSKEHAKVVQQWRIRTESEITADELALTIDGLIGDDSERLTGAAALSTVPSVLHEVRLMLDQ
YWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAFHRFQSPAIVIDFGSSICVDVVSAKGEFLGGAIAPGLQVSS
DAAAARSAALRRVELARPRSVIGKNTVECMQAGAVFGFAGLVDGLVGRIREDVPGFGGDDVAIVATGHTAPLLLPELDTV
SHYDQHLTLHGLRLVFERNRDAQRGRLKTAR
>Mature_271_residues
MLLAIDVRNTHTVVGLISGSKEHAKVVQQWRIRTESEITADELALTIDGLIGDDSERLTGAAALSTVPSVLHEVRLMLDQ
YWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAFHRFQSPAIVIDFGSSICVDVVSAKGEFLGGAIAPGLQVSS
DAAAARSAALRRVELARPRSVIGKNTVECMQAGAVFGFAGLVDGLVGRIREDVPGFGGDDVAIVATGHTAPLLLPELDTV
SHYDQHLTLHGLRLVFERNRDAQRGRLKTAR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 28997; Mature: 28997

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAIDVRNTHTVVGLISGSKEHAKVVQQWRIRTESEITADELALTIDGLIGDDSERLTG
CEEEEEECCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCCHHHHH
AAALSTVPSVLHEVRLMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAF
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEECCHHHHCHHHHHHHHHHH
HRFQSPAIVIDFGSSICVDVVSAKGEFLGGAIAPGLQVSSDAAAARSAALRRVELARPRS
HHCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCHH
VIGKNTVECMQAGAVFGFAGLVDGLVGRIREDVPGFGGDDVAIVATGHTAPLLLPELDTV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCCHHH
SHYDQHLTLHGLRLVFERNRDAQRGRLKTAR
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MLLAIDVRNTHTVVGLISGSKEHAKVVQQWRIRTESEITADELALTIDGLIGDDSERLTG
CEEEEEECCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCCHHHHH
AAALSTVPSVLHEVRLMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAF
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEECCHHHHCHHHHHHHHHHH
HRFQSPAIVIDFGSSICVDVVSAKGEFLGGAIAPGLQVSSDAAAARSAALRRVELARPRS
HHCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCHH
VIGKNTVECMQAGAVFGFAGLVDGLVGRIREDVPGFGGDDVAIVATGHTAPLLLPELDTV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCCHHH
SHYDQHLTLHGLRLVFERNRDAQRGRLKTAR
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA