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The map label for this gene is hemK [C]

Identifier: 41406471

GI number: 41406471

Start: 399375

End: 400064

Strand: Direct

Name: hemK [C]

Synonym: MAP0373

Alternate gene names: 41406471

Gene position: 399375-400064 (Clockwise)

Preceding gene: 41406470

Following gene: 41406478

Centisome position: 8.27

GC content: 69.71

Gene sequence:

>690_bases
GTGACAACCACCTACCCCGAGCCCGCTGTGTTGCCCGCCCACAATGTCTATCAGCCGCAAGAGGATTCCCGGTTGCTGGT
GGACGTGATGCACGGCACCGGTCTGATCCCGGGACGGCGCGTGCTGGACCTGTGCACCGGCAGCGGCTTCGTCGCGATCG
CCGCGGCGGAGATGGGCTGCGCCAGCGTCACGGCGTTCGACAAATGCCCGCACGCCGTGCGGTGCGCCCGGGAGAACGCC
GCGCTGGCCGGGGTGGACGTCGACGTCCGGGAGGGGTCGTGGCTCGCCGCGGTGGATTGCGCGCCGTTCGACGTCGTGGT
GTCCAATCCGCCCTACGTGCCCACCCCGCCCGGCGCCGTGCTGGACGAGCTCGGCCCGGTGACCGGGCCGTCGTGGGCGT
GGAACGCCGGCCGGGACGGCCGGCTGGTCCTGGATCCGTTGTGCGAGTCGGCGCCGAAGCTGTTGCGCGACGGCGGATCG
CTGCTGCTGGTGCACTCGGCGCTGGCCGGTGTGCAGCAGTCGCTGGATTGCCTGAAATGGGCCGGAATGGATGCGAAAGT
CATTGCCTCCAAATGGATCCCGTTCGGTCCGGTGATGTTGTCTCGGGCGCACTGGCTGGAGGACGTCGGCCTGATCCCGC
GCGGGCGCCGCGAAGAGGAGCTGATCGTGATCCGGGCGGAAAAGCGATGA

Upstream 100 bases:

>100_bases
TTTTCGGCTGGTCCGTTTGAATGCGATGGTTTGCGGGCATTATCCACGCCAAGCCGTGAGATCAGCGGCGCTCCTTGTAA
GGGTTCTCGAAAGGCCAACA

Downstream 100 bases:

>100_bases
GCCCCACTAGGGTTCAGGTGGTGCCCAACGGACCGGTGCTGGTCTCGGGGCCGGTGCGCATCGAGATGCCCGGCGGCGAG
GTGGTCGAGTCGGACCGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: M.MjaHemkP [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTTTYPEPAVLPAHNVYQPQEDSRLLVDVMHGTGLIPGRRVLDLCTGSGFVAIAAAEMGCASVTAFDKCPHAVRCARENA
ALAGVDVDVREGSWLAAVDCAPFDVVVSNPPYVPTPPGAVLDELGPVTGPSWAWNAGRDGRLVLDPLCESAPKLLRDGGS
LLLVHSALAGVQQSLDCLKWAGMDAKVIASKWIPFGPVMLSRAHWLEDVGLIPRGRREEELIVIRAEKR

Sequences:

>Translated_229_residues
MTTTYPEPAVLPAHNVYQPQEDSRLLVDVMHGTGLIPGRRVLDLCTGSGFVAIAAAEMGCASVTAFDKCPHAVRCARENA
ALAGVDVDVREGSWLAAVDCAPFDVVVSNPPYVPTPPGAVLDELGPVTGPSWAWNAGRDGRLVLDPLCESAPKLLRDGGS
LLLVHSALAGVQQSLDCLKWAGMDAKVIASKWIPFGPVMLSRAHWLEDVGLIPRGRREEELIVIRAEKR
>Mature_228_residues
TTTYPEPAVLPAHNVYQPQEDSRLLVDVMHGTGLIPGRRVLDLCTGSGFVAIAAAEMGCASVTAFDKCPHAVRCARENAA
LAGVDVDVREGSWLAAVDCAPFDVVVSNPPYVPTPPGAVLDELGPVTGPSWAWNAGRDGRLVLDPLCESAPKLLRDGGSL
LLVHSALAGVQQSLDCLKWAGMDAKVIASKWIPFGPVMLSRAHWLEDVGLIPRGRREEELIVIRAEKR

Specific function: Putative protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Caenorhabditis elegans, GI193204212, Length=160, Percent_Identity=35, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004557
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 24492; Mature: 24361

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTYPEPAVLPAHNVYQPQEDSRLLVDVMHGTGLIPGRRVLDLCTGSGFVAIAAAEMGC
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEECCCCC
ASVTAFDKCPHAVRCARENAALAGVDVDVREGSWLAAVDCAPFDVVVSNPPYVPTPPGAV
HHHHHHHHCCHHHHHHHCCCEEECCEEEECCCCEEEEECCCCEEEEECCCCCCCCCCCHH
LDELGPVTGPSWAWNAGRDGRLVLDPLCESAPKLLRDGGSLLLVHSALAGVQQSLDCLKW
HHHCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
AGMDAKVIASKWIPFGPVMLSRAHWLEDVGLIPRGRREEELIVIRAEKR
CCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
TTTYPEPAVLPAHNVYQPQEDSRLLVDVMHGTGLIPGRRVLDLCTGSGFVAIAAAEMGC
CCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEECCCCC
ASVTAFDKCPHAVRCARENAALAGVDVDVREGSWLAAVDCAPFDVVVSNPPYVPTPPGAV
HHHHHHHHCCHHHHHHHCCCEEECCEEEECCCCEEEEECCCCEEEEECCCCCCCCCCCHH
LDELGPVTGPSWAWNAGRDGRLVLDPLCESAPKLLRDGGSLLLVHSALAGVQQSLDCLKW
HHHCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
AGMDAKVIASKWIPFGPVMLSRAHWLEDVGLIPRGRREEELIVIRAEKR
CCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]