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The map label for this gene is pfpI

Identifier: 41406470

GI number: 41406470

Start: 398710

End: 399264

Strand: Direct

Name: pfpI

Synonym: MAP0372

Alternate gene names: 41406470

Gene position: 398710-399264 (Clockwise)

Preceding gene: 41406469

Following gene: 41406471

Centisome position: 8.26

GC content: 69.19

Gene sequence:

>555_bases
ATGTCAAATGAGTTGCAAGGCAAGAAGATAGCGATCCTGGCGGCCGACGGGGTGGAAAAGGTGGAGCTGGAGCAGCCGGC
GGCGGCGCTGCGCGAGGCTGGCGCCGGCGTCGAGGTGGTCTCGCTGCAGGACGGCGAGATCCAGGCGCGCAACCACGACC
TGGAGCCGGCCGGCACCTTTACCGTCGACCGCAAGGTGGCCGACGCGTCGGTCGACGACTTCGACGGCCTGGTGCTGCCG
GGCGGCACCGTCAACCCCGACAAGCTGCGCCTCGACGACACCGCGGTCTCCTTCGTGCGGGACTTCGTCGGATCCGGCAA
GCCGGTGGCCGCCATCTGCCACGGCCCCTGGACGCTGGTCGAAGCCGGTGTGGCAACGGGCCGGACGCTGACCTCTTATC
CCAGCATCCGCACCGATCTGCGCAACGCGGGCGCCCACGTGGTGGACGAGGAGGTGGTGGTGGACGGCAACCTGATCACC
AGCCGCTCGCCGAAGGACCTGCCGGCGTTCTGCTCGACCATCCTGGCGCAATTCGCGGGCGCCACCACCGGTTAG

Upstream 100 bases:

>100_bases
GGGGACACCCAGGAGAGATTCCTCAAGGAAGCCGCCGAACCGCTGCTGGCGGCGCTGCGCGACGCGGCGAAGTAGCGGCG
AACGAGAAAGGGGAACCGAG

Downstream 100 bases:

>100_bases
CCGTCAACACTTTTCGGCTGGTCCGTTTGAATGCGATGGTTTGCGGGCATTATCCACGCCAAGCCGTGAGATCAGCGGCG
CTCCTTGTAAGGGTTCTCGA

Product: PfpI

Products: NA

Alternate protein names: GSP18 [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSNELQGKKIAILAADGVEKVELEQPAAALREAGAGVEVVSLQDGEIQARNHDLEPAGTFTVDRKVADASVDDFDGLVLP
GGTVNPDKLRLDDTAVSFVRDFVGSGKPVAAICHGPWTLVEAGVATGRTLTSYPSIRTDLRNAGAHVVDEEVVVDGNLIT
SRSPKDLPAFCSTILAQFAGATTG

Sequences:

>Translated_184_residues
MSNELQGKKIAILAADGVEKVELEQPAAALREAGAGVEVVSLQDGEIQARNHDLEPAGTFTVDRKVADASVDDFDGLVLP
GGTVNPDKLRLDDTAVSFVRDFVGSGKPVAAICHGPWTLVEAGVATGRTLTSYPSIRTDLRNAGAHVVDEEVVVDGNLIT
SRSPKDLPAFCSTILAQFAGATTG
>Mature_183_residues
SNELQGKKIAILAADGVEKVELEQPAAALREAGAGVEVVSLQDGEIQARNHDLEPAGTFTVDRKVADASVDDFDGLVLPG
GTVNPDKLRLDDTAVSFVRDFVGSGKPVAAICHGPWTLVEAGVATGRTLTSYPSIRTDLRNAGAHVVDEEVVVDGNLITS
RSPKDLPAFCSTILAQFAGATTG

Specific function: Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=165, Percent_Identity=46.0606060606061, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17531319, Length=177, Percent_Identity=29.9435028248588, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28571932, Length=173, Percent_Identity=36.4161849710983, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653499, Length=181, Percent_Identity=32.5966850828729, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19181; Mature: 19049

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNELQGKKIAILAADGVEKVELEQPAAALREAGAGVEVVSLQDGEIQARNHDLEPAGTF
CCCCCCCCEEEEEECCCCCEEECCCHHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCCE
TVDRKVADASVDDFDGLVLPGGTVNPDKLRLDDTAVSFVRDFVGSGKPVAAICHGPWTLV
EECCEECCCCCCCCCCEEECCCCCCCCCEEECHHHHHHHHHHHCCCCCEEEEECCCHHHH
EAGVATGRTLTSYPSIRTDLRNAGAHVVDEEVVVDGNLITSRSPKDLPAFCSTILAQFAG
HHCCCCCCEECCCCCHHHHHHHCCCEEECCEEEECCCEEECCCCCCHHHHHHHHHHHHCC
ATTG
CCCC
>Mature Secondary Structure 
SNELQGKKIAILAADGVEKVELEQPAAALREAGAGVEVVSLQDGEIQARNHDLEPAGTF
CCCCCCCEEEEEECCCCCEEECCCHHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCCE
TVDRKVADASVDDFDGLVLPGGTVNPDKLRLDDTAVSFVRDFVGSGKPVAAICHGPWTLV
EECCEECCCCCCCCCCEEECCCCCCCCCEEECHHHHHHHHHHHCCCCCEEEEECCCHHHH
EAGVATGRTLTSYPSIRTDLRNAGAHVVDEEVVVDGNLITSRSPKDLPAFCSTILAQFAG
HHCCCCCCEECCCCCHHHHHHHCCCEEECCEEEECCCEEECCCCCCHHHHHHHHHHHHCC
ATTG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 9298659 [H]