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The map label for this gene is yehX [H]

Identifier: 41406371

GI number: 41406371

Start: 292141

End: 292974

Strand: Direct

Name: yehX [H]

Synonym: MAP0273

Alternate gene names: 41406371

Gene position: 292141-292974 (Clockwise)

Preceding gene: 41406370

Following gene: 41406372

Centisome position: 6.05

GC content: 69.66

Gene sequence:

>834_bases
ATGCCGCACCAGAGGGTGATCGACAACGTGGCAACGGTTCCCGTGCTGCGCGGCCAGCGTCGGCGGGCCGCCCGCACGGC
GGCCTACCAGGTGCTCGAGCGCGTCGGGCTGGACGTCAAGTTGGCCCGGCGCTATCCCGCCCAGCTCTCCGGCGGGGAAC
AACAACGGGTCGGCGTGGCTCGCGCGCTGGCCGCCGACCCGCCGATCCTGCTGATGGACGAGCCGTTCTCTGCCGTCGAT
CCGGTGGTGCGTCACGACCTGCAAAACGAAATACTGCGGCTGCAAAGCGAATTGCACAAAACCATCGTCTTCGTCACGCA
CGACATCGACGAGGCGCTGCGGCTCGGCGAACGGGTCGCGGTGTTCAAGGGCGGCGTGTTGCAGCAGTGCGACGAGCCCG
CCCGGCTGCTGTCCCGCCCGGCCAACGACTTCGTGTCGAGGTTCATCGGTCTGGGCCGTGGCTACCGATGGTTGCAACTC
ATCGACGCCGCCGGGCTGCCGGTGCACGACGTCCCCCGCCTGTCCGCCGAAAACCTGTCGGGTGCAGATGTTTTCGATGG
TTGGGCCGTCGTGGTCGACGAGGCCGGGGCGCCGCTGGGCTGGATCGACGCCGAGGGCCTGCGCCGACACCGCGACGGCC
TGGCGCTGTCCGACAGCATGACCGGCGTCGGATCGCTGTTTCGGCCGCGGGGCAACCTGAGCCAGGCGCTGGACGCCGCG
CTGTCGTCGCCGTCGGGAATCGGTGTCGCCGTCGACGACGACGGCAGGGTGATCGGCGGTGTGCTGGCCGCCGACGTGCT
GGCCGCGGTGGAATCGCAGCGAAAGAGCCGCTGA

Upstream 100 bases:

>100_bases
CACGTCCGGCACCATCAGCATCGACGGTGTCGACGTGTCCACCCTCGACCCGGTCAAACTGCGCCTGGGCATCGGCTACG
TCATCCAGCATGCCGGGCTG

Downstream 100 bases:

>100_bases
TGCACTATCTGCTCACCCATCTCGACGACGCGGCCCGGCTCACCGTCGTGCACCTGCGGCTGGCGCTGGTGCCGGTGCTG
ATCGGGTTGGCGATCGCGCT

Product: hypothetical protein

Products: ADP; phosphate; quaternary amine

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MPHQRVIDNVATVPVLRGQRRRAARTAAYQVLERVGLDVKLARRYPAQLSGGEQQRVGVARALAADPPILLMDEPFSAVD
PVVRHDLQNEILRLQSELHKTIVFVTHDIDEALRLGERVAVFKGGVLQQCDEPARLLSRPANDFVSRFIGLGRGYRWLQL
IDAAGLPVHDVPRLSAENLSGADVFDGWAVVVDEAGAPLGWIDAEGLRRHRDGLALSDSMTGVGSLFRPRGNLSQALDAA
LSSPSGIGVAVDDDGRVIGGVLAADVLAAVESQRKSR

Sequences:

>Translated_277_residues
MPHQRVIDNVATVPVLRGQRRRAARTAAYQVLERVGLDVKLARRYPAQLSGGEQQRVGVARALAADPPILLMDEPFSAVD
PVVRHDLQNEILRLQSELHKTIVFVTHDIDEALRLGERVAVFKGGVLQQCDEPARLLSRPANDFVSRFIGLGRGYRWLQL
IDAAGLPVHDVPRLSAENLSGADVFDGWAVVVDEAGAPLGWIDAEGLRRHRDGLALSDSMTGVGSLFRPRGNLSQALDAA
LSSPSGIGVAVDDDGRVIGGVLAADVLAAVESQRKSR
>Mature_276_residues
PHQRVIDNVATVPVLRGQRRRAARTAAYQVLERVGLDVKLARRYPAQLSGGEQQRVGVARALAADPPILLMDEPFSAVDP
VVRHDLQNEILRLQSELHKTIVFVTHDIDEALRLGERVAVFKGGVLQQCDEPARLLSRPANDFVSRFIGLGRGYRWLQLI
DAAGLPVHDVPRLSAENLSGADVFDGWAVVVDEAGAPLGWIDAEGLRRHRDGLALSDSMTGVGSLFRPRGNLSQALDAAL
SSPSGIGVAVDDDGRVIGGVLAADVLAAVESQRKSR

Specific function: May be part of an ABC transporter complex involved in uptake of osmoprotectant molecules. Probably responsible for energy coupling to the transport system [H]

COG id: COG1125

COG function: function code E; ABC-type proline/glycine betaine transport systems, ATPase components

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI105990541, Length=126, Percent_Identity=35.7142857142857, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI116734710, Length=187, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788450, Length=161, Percent_Identity=52.1739130434783, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789032, Length=149, Percent_Identity=47.6510067114094, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787712, Length=150, Percent_Identity=43.3333333333333, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1788761, Length=152, Percent_Identity=45.3947368421053, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787370, Length=152, Percent_Identity=43.421052631579, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1786563, Length=149, Percent_Identity=40.2684563758389, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082267, Length=149, Percent_Identity=38.255033557047, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788644, Length=151, Percent_Identity=37.7483443708609, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790467, Length=149, Percent_Identity=37.5838926174497, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787029, Length=153, Percent_Identity=36.6013071895425, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786872, Length=154, Percent_Identity=37.6623376623377, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87081791, Length=152, Percent_Identity=36.8421052631579, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788506, Length=238, Percent_Identity=31.5126050420168, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87081709, Length=150, Percent_Identity=34.6666666666667, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788225, Length=156, Percent_Identity=37.1794871794872, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786398, Length=144, Percent_Identity=34.7222222222222, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789672, Length=152, Percent_Identity=33.5526315789474, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787089, Length=151, Percent_Identity=34.4370860927152, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787164, Length=125, Percent_Identity=43.2, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI145693107, Length=128, Percent_Identity=35.15625, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787500, Length=105, Percent_Identity=35.2380952380952, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786703, Length=129, Percent_Identity=36.4341085271318, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786253, Length=97, Percent_Identity=37.1134020618557, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789962, Length=101, Percent_Identity=37.6237623762376, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789873, Length=126, Percent_Identity=39.6825396825397, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787758, Length=127, Percent_Identity=32.2834645669291, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789891, Length=98, Percent_Identity=37.7551020408163, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790162, Length=101, Percent_Identity=35.6435643564356, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790544, Length=112, Percent_Identity=36.6071428571429, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081834, Length=129, Percent_Identity=35.6589147286822, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787759, Length=177, Percent_Identity=29.9435028248588, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787105, Length=108, Percent_Identity=37.037037037037, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789963, Length=139, Percent_Identity=27.3381294964029, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994997, Length=125, Percent_Identity=32, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789864, Length=134, Percent_Identity=28.3582089552239, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789593, Length=109, Percent_Identity=35.7798165137615, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787547, Length=126, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=160, Percent_Identity=29.375, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=160, Percent_Identity=29.375, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=160, Percent_Identity=29.375, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=109, Percent_Identity=34.8623853211009, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281362751, Length=114, Percent_Identity=35.9649122807018, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24650855, Length=114, Percent_Identity=35.9649122807018, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650853, Length=114, Percent_Identity=35.9649122807018, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574150, Length=141, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007328, Length=141, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85725262, Length=100, Percent_Identity=33, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.32

Molecular weight: Translated: 29917; Mature: 29786

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHQRVIDNVATVPVLRGQRRRAARTAAYQVLERVGLDVKLARRYPAQLSGGEQQRVGVA
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCHHHHHHH
RALAADPPILLMDEPFSAVDPVVRHDLQNEILRLQSELHKTIVFVTHDIDEALRLGERVA
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHCCHHH
VFKGGVLQQCDEPARLLSRPANDFVSRFIGLGRGYRWLQLIDAAGLPVHDVPRLSAENLS
HHCCCHHHHCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
GADVFDGWAVVVDEAGAPLGWIDAEGLRRHRDGLALSDSMTGVGSLFRPRGNLSQALDAA
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHCCCCCHHHHHHHH
LSSPSGIGVAVDDDGRVIGGVLAADVLAAVESQRKSR
HCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PHQRVIDNVATVPVLRGQRRRAARTAAYQVLERVGLDVKLARRYPAQLSGGEQQRVGVA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCHHHHHHH
RALAADPPILLMDEPFSAVDPVVRHDLQNEILRLQSELHKTIVFVTHDIDEALRLGERVA
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHCCHHH
VFKGGVLQQCDEPARLLSRPANDFVSRFIGLGRGYRWLQLIDAAGLPVHDVPRLSAENLS
HHCCCHHHHCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
GADVFDGWAVVVDEAGAPLGWIDAEGLRRHRDGLALSDSMTGVGSLFRPRGNLSQALDAA
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHCCCCCHHHHHHHH
LSSPSGIGVAVDDDGRVIGGVLAADVLAAVESQRKSR
HCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; quaternary amine

Specific reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]