Click here to switch to the map view.

The map label for this gene is polX [H]

Identifier: 41406275

GI number: 41406275

Start: 184199

End: 185203

Strand: Direct

Name: polX [H]

Synonym: MAP0177

Alternate gene names: 41406275

Gene position: 184199-185203 (Clockwise)

Preceding gene: 41406274

Following gene: 41406278

Centisome position: 3.81

GC content: 69.95

Gene sequence:

>1005_bases
ATGGACCCGGTAGTTGCGCTGCGGCAGATCGCGTACTACAAGGACCGCAGCCGCCACGACCCCAGGCGGGTGATGGCCTA
CCGCAACGCGGCCGATGTCATCGAGGGCCTCGACGAGGCGACGCGGGAGCGCCACGGGCAGGCCAACAGCTGGCAGTCGC
TGCCCGGCATCGGACCCAAGACCGCCAAGGTGATCGCGCAGGCCTGGTCCGGTCGCGAACCCGACATGCTGGTCGAATTG
CGTTCTGCTGCAGAGGATCTCGGTGGCGGCGATATCCGTTCGGCGCTGCGCGGCGATCTGCATGTGCACTCGAACTGGTC
GGACGGTTCGGCGCCGATCGAGGAGATGATGGCCGCCGCGGCGGCGCTCGGTCACGAATACTGCGCGCTGACCGACCATT
CGCCGCGGCTGACCATCGCCAACGGCCTGTCGCCGGAGCGGCTGCGCAAGCAGCTCGACGTGATCGACCGGCTGCAGGAC
ACCGTCGCGCCGATGCGCATCCTGACCGGGATCGAGGTGGACATCCTCGAGGACGGCGGGCTGGACCAGGAACCCGAACT
GCTGGAGCGGCTCGACGTCGTGGTGGCCAGCGTGCACTCCGAGCTGTCGATGGATTCCGCCGCGATGACCCGCCGGATGC
TGCGCGCCGTGCAAAATCCGCACGCCGACGTGCTCGGCCACTGCACCGGCCGGTTGGTGTCCGGCAACCGCGGCATCCGG
CCGGAGTCCAAGTTCGACGCCGAGGCGGTGTTCACCGCCTGCCGCGAGCACGGCACCGCGGTGGAGATCAACTCCCGCCC
GGAACGCCGCGACCCGCCGACCCGGCTGCTGAACCTGGCGCTGGAGATGGGCTGCGTGTTCAGCATCGACACCGATGCGC
ACGCGCCGGGCCAGCTGGAATTCCTCGGCTACGGCGCCCAGCGCGCCCTGGACGCCGGGGTGCCCGTCGACCGGATCGTC
AACACCTGGCCGGCCGAACGGCTGCTGGAGTGGACGGCCGGCTAG

Upstream 100 bases:

>100_bases
CGTCGCCGGACAGCTGTGGTGATCCGCGCGGGGGTTCGGCGGTGATCTCCGGCGCCCGGCCTCTCCGCGCTGGCGGTCAC
CGCGCGGGCACACTGGAGTC

Downstream 100 bases:

>100_bases
GTCCGATCAGTCCGGCAGGTGCGGCATCTCGAGTCCCGGGTCGCGGCCCAGCAACACCGCCGGCGTCAGCGCCGCCTTGC
CGTAGCGGCGCCGCACCCGG

Product: hypothetical protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MDPVVALRQIAYYKDRSRHDPRRVMAYRNAADVIEGLDEATRERHGQANSWQSLPGIGPKTAKVIAQAWSGREPDMLVEL
RSAAEDLGGGDIRSALRGDLHVHSNWSDGSAPIEEMMAAAAALGHEYCALTDHSPRLTIANGLSPERLRKQLDVIDRLQD
TVAPMRILTGIEVDILEDGGLDQEPELLERLDVVVASVHSELSMDSAAMTRRMLRAVQNPHADVLGHCTGRLVSGNRGIR
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLNLALEMGCVFSIDTDAHAPGQLEFLGYGAQRALDAGVPVDRIV
NTWPAERLLEWTAG

Sequences:

>Translated_334_residues
MDPVVALRQIAYYKDRSRHDPRRVMAYRNAADVIEGLDEATRERHGQANSWQSLPGIGPKTAKVIAQAWSGREPDMLVEL
RSAAEDLGGGDIRSALRGDLHVHSNWSDGSAPIEEMMAAAAALGHEYCALTDHSPRLTIANGLSPERLRKQLDVIDRLQD
TVAPMRILTGIEVDILEDGGLDQEPELLERLDVVVASVHSELSMDSAAMTRRMLRAVQNPHADVLGHCTGRLVSGNRGIR
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLNLALEMGCVFSIDTDAHAPGQLEFLGYGAQRALDAGVPVDRIV
NTWPAERLLEWTAG
>Mature_334_residues
MDPVVALRQIAYYKDRSRHDPRRVMAYRNAADVIEGLDEATRERHGQANSWQSLPGIGPKTAKVIAQAWSGREPDMLVEL
RSAAEDLGGGDIRSALRGDLHVHSNWSDGSAPIEEMMAAAAALGHEYCALTDHSPRLTIANGLSPERLRKQLDVIDRLQD
TVAPMRILTGIEVDILEDGGLDQEPELLERLDVVVASVHSELSMDSAAMTRRMLRAVQNPHADVLGHCTGRLVSGNRGIR
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLNLALEMGCVFSIDTDAHAPGQLEFLGYGAQRALDAGVPVDRIV
NTWPAERLLEWTAG

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 36653; Mature: 36653

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPVVALRQIAYYKDRSRHDPRRVMAYRNAADVIEGLDEATRERHGQANSWQSLPGIGPK
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
TAKVIAQAWSGREPDMLVELRSAAEDLGGGDIRSALRGDLHVHSNWSDGSAPIEEMMAAA
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHH
AALGHEYCALTDHSPRLTIANGLSPERLRKQLDVIDRLQDTVAPMRILTGIEVDILEDGG
HHHCCCCEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
LDQEPELLERLDVVVASVHSELSMDSAAMTRRMLRAVQNPHADVLGHCTGRLVSGNRGIR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCEEECCCCCCC
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLNLALEMGCVFSIDTDAHAPGQLE
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCEE
FLGYGAQRALDAGVPVDRIVNTWPAERLLEWTAG
EECCCHHHHHHCCCCHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MDPVVALRQIAYYKDRSRHDPRRVMAYRNAADVIEGLDEATRERHGQANSWQSLPGIGPK
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
TAKVIAQAWSGREPDMLVELRSAAEDLGGGDIRSALRGDLHVHSNWSDGSAPIEEMMAAA
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCCCCCHHHHHHHH
AALGHEYCALTDHSPRLTIANGLSPERLRKQLDVIDRLQDTVAPMRILTGIEVDILEDGG
HHHCCCCEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC
LDQEPELLERLDVVVASVHSELSMDSAAMTRRMLRAVQNPHADVLGHCTGRLVSGNRGIR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCEEECCCCCCC
PESKFDAEAVFTACREHGTAVEINSRPERRDPPTRLLNLALEMGCVFSIDTDAHAPGQLE
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCEE
FLGYGAQRALDAGVPVDRIVNTWPAERLLEWTAG
EECCCHHHHHHCCCCHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]