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The map label for this gene is eccA2 [H]

Identifier: 41406265

GI number: 41406265

Start: 170466

End: 172307

Strand: Direct

Name: eccA2 [H]

Synonym: MAP0167

Alternate gene names: 41406265

Gene position: 170466-172307 (Clockwise)

Preceding gene: 41406264

Following gene: 41406268

Centisome position: 3.53

GC content: 69.11

Gene sequence:

>1842_bases
GTGATGGGTGATTTGCAAACTGCCCGAAGGCATTTCGACCGCGCCATGGCGATCATGAGCCGCCAGGGGCGGGCGGCCGC
GTTGCCGGAGTTCGTCGCCGCCACCGACGCCGACCCGTCGATGGCCGATGCGTGGCTGGGGCGCATCGCGTGCGGCGACA
GCGAGCTGGCGTCGCTGCGCAAGCTCTACGCCACCAGCGAATGGCTGCACCGCGAGACCACCCGGATCGGGCAGACCCTG
GCCGCCGAGATCCAGCTGGGCCCCTACATCGGCATCACCGTCACCGACGCCTCGCAGGTCGGGCTGGCGCTGTCGTCCGC
GCTGACCATCGCCGGGGAGTACGCCGAGGCCGACAAGCTGCTGGCCAACCGCGACCTGCTGGACTCGTGGACCAACTACC
AGTGGCACCAGCTGGCCCGCACCTTCTTGATGTACCGGACGCAGCGCTGGCCGGATGTGTTGTTGACGGCCGCGGAGGAG
TTGCCGCCGCAGGCCATCATCATGTCGGCGGTGACGGCCTCGATCTGCGCGCTGGCCGCGCACGCCGCCGCCCACCTGGG
CCAGGGGCGGGTGGCGCTGGACTGGCTGGACCGGGTCGACGTCATCGGGCAGACCCAGGCGTCGTCGCGCTTCGACGCCG
ATGTGCTGACCGCGTCCATCGGCCCGGCCGACATCCCGCTGCTGGTCGCCGATCTGGCCTACGTGCGCGGGATGGTGCAC
CGCCAGCTGGGCGAGGAGGACAAGGCCCAGATCTGGCTGTCCAAGGCCACCATCAACGGCGTCCTCACCGAGCCCGCCAA
GGAGGCACTGGCCGACCCGAACCTGCACCTGGTGATCACCGACGAACAAACCATCGACAGCCGCACCGACCGGTGGGACG
CCTCGTCGGCCAAGAGCCGCGACGAGCTCGATGACGACGCCGCCGCCGAACGGCGCGCCGAGCTGCTGGCCGAGGGCCGC
CGGCTGCTGGCCAAACAGGTGGGGCTGGCCGCGGTCAAACAGGCGGTCGCCGCGCTGGAGGACCAACTCGAAGTGCGGAT
GATGCGCCTCGAGCACGGCCTGCCGGTGGAGGGCCAGACCAACCACATGCTGCTGGTCGGCCCGCCGGGCACCGGTAAGA
CGACCACCGCCGAGGCGCTGGGCAAGATCTACGCCGGCATGGGAATCGTGCGCCACCCCGAGATCCGCGAGGTGCGCCGA
TCGGACTTCTGCGGGCACTTCATCGGCGAGTCGGGCCCCAAGACCAACGAGTTGATCGAAAAGTCCTTGGGCCGAATCAT
TTTCATGGAAGAGTTCTACTCGCTGATCGAGCGCCATCAGGACGGTACGCCCGACATGATCGGCATGGAGGCGGTCAACC
AGCTGCTGGTCGCCCTGGAGGCGCACCGCTTCGACTTCTGCTTCATCGGCGCCGGCTACGAAGACCAGGTGGACCAATTC
CTCACCGTCAACCCGGGTTTGGCGGGCCGGTTCAACCGCAAGCTGCGGTTCGAGTCCTACTCGCCGGCCGAGATCGTCGA
GATCGCGCACCGCTACGCCACCCCGCGCGCCAGCCTGCTCGACGAGGCCGCGCGCGAGACGCTGCTGGACGCGGCGACCA
CCATCCGCAACTACACCACTCCCGGCGGCCGGCACGGCATCGACGCGATGCAGAACGGCCGGTTCGCCCGCAGCGTCGTC
GAACGCGCCGAGGGCTTCCGCGACACCCGGGTGGTCGCGCAGAAGCGTGCCGGCCAACCGGTCACGGTGGATGACCTCAA
GATCATCACCGCCGCCGACATCGAGGCGGCGGTGCGCAGCGTGTGTTCGGACAACCGCGACATGGCCGCCATCGTCTGGT
GA

Upstream 100 bases:

>100_bases
TCGAGATGGACATGTTCCGCGCCGAGCACCGCTACGTCAGCCTGGAGCCGGTCAGCATGTCCGTCGGCATGTAGCGACGC
CGGTGCTCTGATGGGGGAAT

Downstream 100 bases:

>100_bases
GCGGCGCCCGCCGTCACGCCGGGTCGAAGCGGAAGACGGCGAGTTGCCCTGCCAGCGCCTCGAATTCGTCGGCCGTGCCG
TCGCGCACCAGCCCCGACCG

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component A2; Type VII secretion system protein EccA2; T7SS protein EccA2 [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MMGDLQTARRHFDRAMAIMSRQGRAAALPEFVAATDADPSMADAWLGRIACGDSELASLRKLYATSEWLHRETTRIGQTL
AAEIQLGPYIGITVTDASQVGLALSSALTIAGEYAEADKLLANRDLLDSWTNYQWHQLARTFLMYRTQRWPDVLLTAAEE
LPPQAIIMSAVTASICALAAHAAAHLGQGRVALDWLDRVDVIGQTQASSRFDADVLTASIGPADIPLLVADLAYVRGMVH
RQLGEEDKAQIWLSKATINGVLTEPAKEALADPNLHLVITDEQTIDSRTDRWDASSAKSRDELDDDAAAERRAELLAEGR
RLLAKQVGLAAVKQAVAALEDQLEVRMMRLEHGLPVEGQTNHMLLVGPPGTGKTTTAEALGKIYAGMGIVRHPEIREVRR
SDFCGHFIGESGPKTNELIEKSLGRIIFMEEFYSLIERHQDGTPDMIGMEAVNQLLVALEAHRFDFCFIGAGYEDQVDQF
LTVNPGLAGRFNRKLRFESYSPAEIVEIAHRYATPRASLLDEAARETLLDAATTIRNYTTPGGRHGIDAMQNGRFARSVV
ERAEGFRDTRVVAQKRAGQPVTVDDLKIITAADIEAAVRSVCSDNRDMAAIVW

Sequences:

>Translated_613_residues
MMGDLQTARRHFDRAMAIMSRQGRAAALPEFVAATDADPSMADAWLGRIACGDSELASLRKLYATSEWLHRETTRIGQTL
AAEIQLGPYIGITVTDASQVGLALSSALTIAGEYAEADKLLANRDLLDSWTNYQWHQLARTFLMYRTQRWPDVLLTAAEE
LPPQAIIMSAVTASICALAAHAAAHLGQGRVALDWLDRVDVIGQTQASSRFDADVLTASIGPADIPLLVADLAYVRGMVH
RQLGEEDKAQIWLSKATINGVLTEPAKEALADPNLHLVITDEQTIDSRTDRWDASSAKSRDELDDDAAAERRAELLAEGR
RLLAKQVGLAAVKQAVAALEDQLEVRMMRLEHGLPVEGQTNHMLLVGPPGTGKTTTAEALGKIYAGMGIVRHPEIREVRR
SDFCGHFIGESGPKTNELIEKSLGRIIFMEEFYSLIERHQDGTPDMIGMEAVNQLLVALEAHRFDFCFIGAGYEDQVDQF
LTVNPGLAGRFNRKLRFESYSPAEIVEIAHRYATPRASLLDEAARETLLDAATTIRNYTTPGGRHGIDAMQNGRFARSVV
ERAEGFRDTRVVAQKRAGQPVTVDDLKIITAADIEAAVRSVCSDNRDMAAIVW
>Mature_613_residues
MMGDLQTARRHFDRAMAIMSRQGRAAALPEFVAATDADPSMADAWLGRIACGDSELASLRKLYATSEWLHRETTRIGQTL
AAEIQLGPYIGITVTDASQVGLALSSALTIAGEYAEADKLLANRDLLDSWTNYQWHQLARTFLMYRTQRWPDVLLTAAEE
LPPQAIIMSAVTASICALAAHAAAHLGQGRVALDWLDRVDVIGQTQASSRFDADVLTASIGPADIPLLVADLAYVRGMVH
RQLGEEDKAQIWLSKATINGVLTEPAKEALADPNLHLVITDEQTIDSRTDRWDASSAKSRDELDDDAAAERRAELLAEGR
RLLAKQVGLAAVKQAVAALEDQLEVRMMRLEHGLPVEGQTNHMLLVGPPGTGKTTTAEALGKIYAGMGIVRHPEIREVRR
SDFCGHFIGESGPKTNELIEKSLGRIIFMEEFYSLIERHQDGTPDMIGMEAVNQLLVALEAHRFDFCFIGAGYEDQVDQF
LTVNPGLAGRFNRKLRFESYSPAEIVEIAHRYATPRASLLDEAARETLLDAATTIRNYTTPGGRHGIDAMQNGRFARSVV
ERAEGFRDTRVVAQKRAGQPVTVDDLKIITAADIEAAVRSVCSDNRDMAAIVW

Specific function: Shows ATPase activity. Could provide energy for export of ESX-2 substrates [H]

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: NA

Molecular weight: Translated: 67262; Mature: 67262

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGDLQTARRHFDRAMAIMSRQGRAAALPEFVAATDADPSMADAWLGRIACGDSELASLR
CCCCHHHHHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
KLYATSEWLHRETTRIGQTLAAEIQLGPYIGITVTDASQVGLALSSALTIAGEYAEADKL
HHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LANRDLLDSWTNYQWHQLARTFLMYRTQRWPDVLLTAAEELPPQAIIMSAVTASICALAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HAAAHLGQGRVALDWLDRVDVIGQTQASSRFDADVLTASIGPADIPLLVADLAYVRGMVH
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHH
RQLGEEDKAQIWLSKATINGVLTEPAKEALADPNLHLVITDEQTIDSRTDRWDASSAKSR
HHHCCCCHHHEEEEHHHHCCCCCCCHHHHHCCCCEEEEEECCHHHCCCCCCCCCCCCCCC
DELDDDAAAERRAELLAEGRRLLAKQVGLAAVKQAVAALEDQLEVRMMRLEHGLPVEGQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NHMLLVGPPGTGKTTTAEALGKIYAGMGIVRHPEIREVRRSDFCGHFIGESGPKTNELIE
CEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCCCCCHHHHHH
KSLGRIIFMEEFYSLIERHQDGTPDMIGMEAVNQLLVALEAHRFDFCFIGAGYEDQVDQF
HHHCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCE
LTVNPGLAGRFNRKLRFESYSPAEIVEIAHRYATPRASLLDEAARETLLDAATTIRNYTT
EEECCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PGGRHGIDAMQNGRFARSVVERAEGFRDTRVVAQKRAGQPVTVDDLKIITAADIEAAVRS
CCCCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEECCEEEEEHHHHHHHHHH
VCSDNRDMAAIVW
HHCCCCCEEEEEC
>Mature Secondary Structure
MMGDLQTARRHFDRAMAIMSRQGRAAALPEFVAATDADPSMADAWLGRIACGDSELASLR
CCCCHHHHHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
KLYATSEWLHRETTRIGQTLAAEIQLGPYIGITVTDASQVGLALSSALTIAGEYAEADKL
HHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LANRDLLDSWTNYQWHQLARTFLMYRTQRWPDVLLTAAEELPPQAIIMSAVTASICALAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HAAAHLGQGRVALDWLDRVDVIGQTQASSRFDADVLTASIGPADIPLLVADLAYVRGMVH
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHH
RQLGEEDKAQIWLSKATINGVLTEPAKEALADPNLHLVITDEQTIDSRTDRWDASSAKSR
HHHCCCCHHHEEEEHHHHCCCCCCCHHHHHCCCCEEEEEECCHHHCCCCCCCCCCCCCCC
DELDDDAAAERRAELLAEGRRLLAKQVGLAAVKQAVAALEDQLEVRMMRLEHGLPVEGQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NHMLLVGPPGTGKTTTAEALGKIYAGMGIVRHPEIREVRRSDFCGHFIGESGPKTNELIE
CEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCCCCCHHHHHH
KSLGRIIFMEEFYSLIERHQDGTPDMIGMEAVNQLLVALEAHRFDFCFIGAGYEDQVDQF
HHHCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCE
LTVNPGLAGRFNRKLRFESYSPAEIVEIAHRYATPRASLLDEAARETLLDAATTIRNYTT
EEECCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PGGRHGIDAMQNGRFARSVVERAEGFRDTRVVAQKRAGQPVTVDDLKIITAADIEAAVRS
CCCCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEECCEEEEEHHHHHHHHHH
VCSDNRDMAAIVW
HHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]