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The map label for this gene is sodB

Identifier: 52843161

GI number: 52843161

Start: 3356177

End: 3356767

Strand: Direct

Name: sodB

Synonym: lpg2967

Alternate gene names: 52843161

Gene position: 3356177-3356767 (Clockwise)

Preceding gene: 52843158

Following gene: 52843162

Centisome position: 98.78

GC content: 41.46

Gene sequence:

>591_bases
CTGGAGATTGATATGACTTTTACCCTGCCGCAATTACCTTATGCATTGGATGCACTGGCTCCTCATGTTTCCAAAGAAAC
CTTGGAATACCATTATGGTAAACACCATAACACTTACGTCACCAACTTAAATAAATTAATTCCCGGAACAGAATTTGAAT
CCATGACTCTGGAAGAGATCATCATGAAAGCTAAAGGCGGTATTTTTAACAACGCCGCTCAGGTTTGGAATCACACCTTT
TATTGGCACAGCATGAGCCCTAATGGTGGAGGTGAGCCAAAAGGCAGGCTGGCGGAAGCCATTAATAAAAGCTTTGGTTC
TTTTGCAGCATTCAAAGAACAATTTTCACAAACAGCTGCTACAACATTCGGTTCCGGGTGGGCATGGCTAGTCCAGGATC
AGTCAGGGGCTTTAAAAATTATCAACACAAGCAATGCTGGAACACCAATGACTGAAGGATTAAATGCCTTATTAACTTGT
GACGTATGGGAGCACGCTTATTACATCGATTATAGAAATAGGCGCCCGGATTATATTGAAGCCTTTTGGTCATTAGTTAA
TTGGGATTTTGCGAGCAGTAATCTGAAATAA

Upstream 100 bases:

>100_bases
GCAGAAATGTATCCATGGCCAAGACTATAAAAATATTGAATCGCTCAGTAATGGCACATTGAATATCACACTTATCCTGA
TAAACTAAAGACTTTTAATC

Downstream 100 bases:

>100_bases
AATAACAAGCTGGATTTGTTGCAATCCCTACCGGATAATTTTATGTTTATGGAGACATCATGAGTTTAATTACAAGTTAC
AGCCCAATGCCTGTAACCTT

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MEIDMTFTLPQLPYALDALAPHVSKETLEYHYGKHHNTYVTNLNKLIPGTEFESMTLEEIIMKAKGGIFNNAAQVWNHTF
YWHSMSPNGGGEPKGRLAEAINKSFGSFAAFKEQFSQTAATTFGSGWAWLVQDQSGALKIINTSNAGTPMTEGLNALLTC
DVWEHAYYIDYRNRRPDYIEAFWSLVNWDFASSNLK

Sequences:

>Translated_196_residues
MEIDMTFTLPQLPYALDALAPHVSKETLEYHYGKHHNTYVTNLNKLIPGTEFESMTLEEIIMKAKGGIFNNAAQVWNHTF
YWHSMSPNGGGEPKGRLAEAINKSFGSFAAFKEQFSQTAATTFGSGWAWLVQDQSGALKIINTSNAGTPMTEGLNALLTC
DVWEHAYYIDYRNRRPDYIEAFWSLVNWDFASSNLK
>Mature_196_residues
MEIDMTFTLPQLPYALDALAPHVSKETLEYHYGKHHNTYVTNLNKLIPGTEFESMTLEEIIMKAKGGIFNNAAQVWNHTF
YWHSMSPNGGGEPKGRLAEAINKSFGSFAAFKEQFSQTAATTFGSGWAWLVQDQSGALKIINTSNAGTPMTEGLNALLTC
DVWEHAYYIDYRNRRPDYIEAFWSLVNWDFASSNLK

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=193, Percent_Identity=41.9689119170984, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI67782305, Length=193, Percent_Identity=41.9689119170984, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI67782309, Length=185, Percent_Identity=36.7567567567568, Blast_Score=117, Evalue=9e-27,
Organism=Escherichia coli, GI1787946, Length=191, Percent_Identity=67.5392670157068, Blast_Score=284, Evalue=3e-78,
Organism=Escherichia coli, GI1790342, Length=205, Percent_Identity=42.9268292682927, Blast_Score=167, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17506561, Length=190, Percent_Identity=37.8947368421053, Blast_Score=130, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17569479, Length=191, Percent_Identity=36.1256544502618, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321796, Length=205, Percent_Identity=36.5853658536585, Blast_Score=121, Evalue=6e-29,
Organism=Drosophila melanogaster, GI17136812, Length=194, Percent_Identity=38.1443298969072, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 22128; Mature: 22128

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIDMTFTLPQLPYALDALAPHVSKETLEYHYGKHHNTYVTNLNKLIPGTEFESMTLEEI
CEEEEEEECCCCCHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
IMKAKGGIFNNAAQVWNHTFYWHSMSPNGGGEPKGRLAEAINKSFGSFAAFKEQFSQTAA
HHHHCCCCCCCHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTFGSGWAWLVQDQSGALKIINTSNAGTPMTEGLNALLTCDVWEHAYYIDYRNRRPDYIE
HHCCCCEEEEEECCCCCEEEEECCCCCCCHHHCCCEEEEEEECCCEEEEECCCCCCHHHH
AFWSLVNWDFASSNLK
HHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEIDMTFTLPQLPYALDALAPHVSKETLEYHYGKHHNTYVTNLNKLIPGTEFESMTLEEI
CEEEEEEECCCCCHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
IMKAKGGIFNNAAQVWNHTFYWHSMSPNGGGEPKGRLAEAINKSFGSFAAFKEQFSQTAA
HHHHCCCCCCCHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTFGSGWAWLVQDQSGALKIINTSNAGTPMTEGLNALLTCDVWEHAYYIDYRNRRPDYIE
HHCCCCEEEEEECCCCCEEEEECCCCCCCHHHCCCEEEEEEECCCEEEEECCCCCCHHHH
AFWSLVNWDFASSNLK
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9086394 [H]