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The map label for this gene is apaH

Identifier: 52843120

GI number: 52843120

Start: 3312093

End: 3312938

Strand: Reverse

Name: apaH

Synonym: lpg2926

Alternate gene names: 52843120

Gene position: 3312938-3312093 (Counterclockwise)

Preceding gene: 52843121

Following gene: 52843119

Centisome position: 97.5

GC content: 45.27

Gene sequence:

>846_bases
TTGGAGCAAAACGCGGTGCCTGATTATGCAATAGGGGATGTACAAGGTTGTTATGATCCTTTACAACGTTTGCTTGAGCT
AATTGATTTTAACGAGAAGGAAGATTGCTTGTGGTTTGTTGGGGACTTGGTAAACCGCGGTCCTGATTCATTGGCTGTAT
TACGGTTTATTTATTCCTTGCCTGTGAAGCCCAAAATAACCTTGGGTAATCATGATTTGCATTTATTAGGCTTATTATTC
GGCGGGCAACCCTGGAAAGGGCATGATGATACACTTGAAGAGGTGATGCTGGCTGATGATGGAGAGGAGCTTGGGCATTG
GTTGCGCAAGCAATCCCTTCTTTGCAGGTCATCTGAGTTAAACATAGTCATGTGTCATGCAGGTATTGCTCCTTTATGGG
ATTTATCGAAGGCCATGGACCTGGCTAATGAATTAGAAGCGGTGCTTTCAGGCGATTCATATCACGAATTTTTCGCCCAG
ATGTACGGCAATAAGCCGGATATTTGGTCAGATGATTTGGTTGGGCTGGATAGATTACGAGTCATTACCAATTATTTTAC
CCGGATGCGCTATTGTGATGCCCATGGACGATTAGATTTGGGTTATAAAGGGACTTTATCCAAAGCCCCCAATCATCTGT
ATCCCTGGTTTGAAGTGCCATGCCGAAAAGAAATTGAAATGGATATCGTTTTTGGTCATTGGGCGGCGCTCATGGGGCGA
AGTTCTCATCCGCGGATTCATGCGATAGATACCGGATGTCTTTGGGGTGGGCAATTAACGGCATTACGCCTGCAGGACAG
GCAACGCTTTTCGGTACCCGGGTATGGGGTTAGTCGTTTTGAATAA

Upstream 100 bases:

>100_bases
TTCACACAGCAATCAAGTGCGATTGCAATAGCCCCTTTGCAGCGATTGGCAGCCAATGGCCAATGGCAGAATATTGAGCA
GGATATATCCCAATTGACAC

Downstream 100 bases:

>100_bases
CCTTGATGGATAGGCATTTTTATAAACACAGGCGATAACAACGGTGAAATTTTTAAATAAAAGCACAGCATTGTTACCGG
TAATTATTTTATCGGGCCTG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MEQNAVPDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLF
GGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAMDLANELEAVLSGDSYHEFFAQ
MYGNKPDIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGR
SSHPRIHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE

Sequences:

>Translated_281_residues
MEQNAVPDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLF
GGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAMDLANELEAVLSGDSYHEFFAQ
MYGNKPDIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGR
SSHPRIHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE
>Mature_281_residues
MEQNAVPDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSLPVKPKITLGNHDLHLLGLLF
GGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSELNIVMCHAGIAPLWDLSKAMDLANELEAVLSGDSYHEFFAQ
MYGNKPDIWSDDLVGLDRLRVITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGR
SSHPRIHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=265, Percent_Identity=50.188679245283, Blast_Score=254, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31995; Mature: 31995

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNAVPDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHC
PVKPKITLGNHDLHLLGLLFGGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSEL
CCCCEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
NIVMCHAGIAPLWDLSKAMDLANELEAVLSGDSYHEFFAQMYGNKPDIWSDDLVGLDRLR
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGR
HHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCC
SSHPRIHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE
CCCCEEEEEECCEEECCCEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEQNAVPDYAIGDVQGCYDPLQRLLELIDFNEKEDCLWFVGDLVNRGPDSLAVLRFIYSL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHC
PVKPKITLGNHDLHLLGLLFGGQPWKGHDDTLEEVMLADDGEELGHWLRKQSLLCRSSEL
CCCCEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
NIVMCHAGIAPLWDLSKAMDLANELEAVLSGDSYHEFFAQMYGNKPDIWSDDLVGLDRLR
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VITNYFTRMRYCDAHGRLDLGYKGTLSKAPNHLYPWFEVPCRKEIEMDIVFGHWAALMGR
HHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHCC
SSHPRIHAIDTGCLWGGQLTALRLQDRQRFSVPGYGVSRFE
CCCCEEEEEECCEEECCCEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA