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The map label for this gene is prkA

Identifier: 52843006

GI number: 52843006

Start: 3167838

End: 3169844

Strand: Direct

Name: prkA

Synonym: lpg2810

Alternate gene names: 52843006

Gene position: 3167838-3169844 (Clockwise)

Preceding gene: 52843003

Following gene: 52843007

Centisome position: 93.23

GC content: 39.86

Gene sequence:

>2007_bases
TTGCTTTTATACAGGAAAGAGAAAAAAAAGAATCACATTATATCCTTCTCAGGGTTAAGTAAAAGGGGATGGCGCATGAA
TACACAAGATTTTTTAGCGGGTTATACCAAACGATTTGTTGATAACAAAGAAGAAGACATGAGTTTGGATGAATATCTGG
AGTTGTGCAAAACGGACCCGACAGCATATGCCAACCCAGCAGAACGTTTGCTCATGGCGATAGGCGAGCCTGAATTGATC
GATACCCGACATGATCCGGTTCTATCACGAATTTTCTCAAATAAAATAATCCATCATTATGAAGTTTTTAAAGATTTTTA
TGGAATGGAAGAACCCATTGAGCAAATCGTTGGCTTTTTGAAACATGCTGCGCAAGGGTTAGAGGAAACAAAACAGGTTT
TATATCTTTTGGGGCCTGTTGGCGGTGGTAAATCTTCCATTGCAGAAAAATTGAAAGATTTAATGGAAAGAATCCCTTTT
TATGCAATCAAAGGTTCTCCTGTCTTTGAATCTCCACTGTCATTATTTAACCCCTTGGAAGATGGTGAATTACTTAGAGA
ACGTTTTGGTATCCCAACACGCTACCTACGCTACTTAATGTCCCCCTGGGCAGTCAAGCGATTACAGGAATACAATGGCG
ACATCAGCAAATTCCGGGTTATTAAAGTCAAGCCTTCTCGACTCAAACAAATTGCCATTGCAAAAACAGAACCTGGCGAT
GAAAACAATCAAGACATTTCTTCACTGGTTGGTAAAGTCGATATCCGTAAATTGGAAGAATTTTCCCAAGATGATCCTGA
TGCTTACAGCTACTCTGGAGGCTTGTGTCGAGCTAACCGCGGACTTTTGGAGTTCGTTGAAATGTTTAAGGCACCGATAA
AGGTCCTTCATCCCTTGCTGACCGCAACGCAAGAAGGGAATTACAATGCCACAGAAGGGCTTTCAGCTATTCCTTTTGAA
GGAATTATACTAGCCCACTCCAATGAATCAGAATGGCAATCATTTAGAAACAATAAAAATAACGAGGCATTTATAGACCG
AATCAACATAGTCAAAGTGCCTTATTGCCTGCGTGTTTCTGAAGAAATCAAAATCTATCAAAAACTAATCCATAACAGTT
CTTTAGCAAATGCCCCTTGCGCACCTGGTACACTGGATATGCTAGCCCAGTTTTCTGTATTAACCCGTTTAAAAGAACCA
CAAAACTCCAGTATTTACTCCAAAATGCGCGTGTATAATGGAGAGAGTTTGAAAGATACCGATCCCAAGGCAAAATCGTA
TCAGGAGTATAGAGATTTTGCAGGGGTTGACGAAGGGATGAGCGGAATATCCACGCGGTTTGCCTTCAAAATCCTTTCAA
AAGTATTCAATTTTGATCATACTGAAGTGGCCGCCAACCCGGTTCATTTAATGTATGTGCTGGAACGCCAAATCGAACAG
GAACAATTTCCTCAAGAGTTACATGAAACCTACTTGAACTTCATTAAAGAATATTTGGCGACCAAATACGTCGATTTTAT
AGGCAAGGAAATTCAAACCGCTTACCTGGAATCCTATTCTGAGTATGGGCAGAACATATTTGACCGTTACATTACCTATG
CTGATTTCTGGATTCAAGATCAGGATTATCGCGATCCGGATACTGGCGAGATATTTGACAGAGCCTTATTAAACCTGGAA
CTGGAGAAAATCGAAAAACCGGCAGGGATCTCCAATCCTAAAGACTTCCGTAATGAAGTAGTCAATTTCGTACTGCGCGC
TCGAGCAAATAACCGAGGAAAAAACCCTGTATGGAATAGCTATGAAAAACTAAAATCAGTGATTGAGAAAAAAATGTTTA
CCAATACGGAAGATTTGTTACCCGTTATTTCTTTCAATGCCAAAGCATCTGAGGAAGATAAGAAAAAACACGAAGAGTTT
ATCTCTCGAATGGTAGAAAAAGGCTACACACGAAAACAAGTTCGCTTACTTTGTGAATGGTATTTGAGAGTAAGGAAGTC
ACAATAA

Upstream 100 bases:

>100_bases
CATAGTCATTGCTTCCTATAAAAAAAACGAATAAGTTTATTGATTTATGTATTAAATTAAGTGGTTAGTCTACTATACTA
TGAATTAAAAGAAGTAATTT

Downstream 100 bases:

>100_bases
TAGGTAGGATCATTCATAACTCAATAGGTTATGAAATACAGTCAGGGTTAATAAGTAACTATCTGAAAAGATCAAGTAGA
ATCCTAAATTCAGATACTGC

Product: serine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MLLYRKEKKKNHIISFSGLSKRGWRMNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDPTAYANPAERLLMAIGEPELI
DTRHDPVLSRIFSNKIIHHYEVFKDFYGMEEPIEQIVGFLKHAAQGLEETKQVLYLLGPVGGGKSSIAEKLKDLMERIPF
YAIKGSPVFESPLSLFNPLEDGELLRERFGIPTRYLRYLMSPWAVKRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGD
ENNQDISSLVGKVDIRKLEEFSQDDPDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLLTATQEGNYNATEGLSAIPFE
GIILAHSNESEWQSFRNNKNNEAFIDRINIVKVPYCLRVSEEIKIYQKLIHNSSLANAPCAPGTLDMLAQFSVLTRLKEP
QNSSIYSKMRVYNGESLKDTDPKAKSYQEYRDFAGVDEGMSGISTRFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQ
EQFPQELHETYLNFIKEYLATKYVDFIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQDQDYRDPDTGEIFDRALLNLE
LEKIEKPAGISNPKDFRNEVVNFVLRARANNRGKNPVWNSYEKLKSVIEKKMFTNTEDLLPVISFNAKASEEDKKKHEEF
ISRMVEKGYTRKQVRLLCEWYLRVRKSQ

Sequences:

>Translated_668_residues
MLLYRKEKKKNHIISFSGLSKRGWRMNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDPTAYANPAERLLMAIGEPELI
DTRHDPVLSRIFSNKIIHHYEVFKDFYGMEEPIEQIVGFLKHAAQGLEETKQVLYLLGPVGGGKSSIAEKLKDLMERIPF
YAIKGSPVFESPLSLFNPLEDGELLRERFGIPTRYLRYLMSPWAVKRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGD
ENNQDISSLVGKVDIRKLEEFSQDDPDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLLTATQEGNYNATEGLSAIPFE
GIILAHSNESEWQSFRNNKNNEAFIDRINIVKVPYCLRVSEEIKIYQKLIHNSSLANAPCAPGTLDMLAQFSVLTRLKEP
QNSSIYSKMRVYNGESLKDTDPKAKSYQEYRDFAGVDEGMSGISTRFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQ
EQFPQELHETYLNFIKEYLATKYVDFIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQDQDYRDPDTGEIFDRALLNLE
LEKIEKPAGISNPKDFRNEVVNFVLRARANNRGKNPVWNSYEKLKSVIEKKMFTNTEDLLPVISFNAKASEEDKKKHEEF
ISRMVEKGYTRKQVRLLCEWYLRVRKSQ
>Mature_668_residues
MLLYRKEKKKNHIISFSGLSKRGWRMNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDPTAYANPAERLLMAIGEPELI
DTRHDPVLSRIFSNKIIHHYEVFKDFYGMEEPIEQIVGFLKHAAQGLEETKQVLYLLGPVGGGKSSIAEKLKDLMERIPF
YAIKGSPVFESPLSLFNPLEDGELLRERFGIPTRYLRYLMSPWAVKRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGD
ENNQDISSLVGKVDIRKLEEFSQDDPDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLLTATQEGNYNATEGLSAIPFE
GIILAHSNESEWQSFRNNKNNEAFIDRINIVKVPYCLRVSEEIKIYQKLIHNSSLANAPCAPGTLDMLAQFSVLTRLKEP
QNSSIYSKMRVYNGESLKDTDPKAKSYQEYRDFAGVDEGMSGISTRFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQ
EQFPQELHETYLNFIKEYLATKYVDFIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQDQDYRDPDTGEIFDRALLNLE
LEKIEKPAGISNPKDFRNEVVNFVLRARANNRGKNPVWNSYEKLKSVIEKKMFTNTEDLLPVISFNAKASEEDKKKHEEF
ISRMVEKGYTRKQVRLLCEWYLRVRKSQ

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=637, Percent_Identity=74.7252747252747, Blast_Score=1022, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 77404; Mature: 77404

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLYRKEKKKNHIISFSGLSKRGWRMNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDP
CCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCCC
TAYANPAERLLMAIGEPELIDTRHDPVLSRIFSNKIIHHYEVFKDFYGMEEPIEQIVGFL
CCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KHAAQGLEETKQVLYLLGPVGGGKSSIAEKLKDLMERIPFYAIKGSPVFESPLSLFNPLE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHCHHHHHCCCC
DGELLRERFGIPTRYLRYLMSPWAVKRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGD
CHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCHHHEEEEEECHHHHHHHHEECCCCCC
ENNQDISSLVGKVDIRKLEEFSQDDPDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHH
TATQEGNYNATEGLSAIPFEGIILAHSNESEWQSFRNNKNNEAFIDRINIVKVPYCLRVS
HHCCCCCCCHHCCCCCCCCCCEEEEECCHHHHHHHHCCCCCHHHHHHHHEEECCHHHHHH
EEIKIYQKLIHNSSLANAPCAPGTLDMLAQFSVLTRLKEPQNSSIYSKMRVYNGESLKDT
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCC
DPKAKSYQEYRDFAGVDEGMSGISTRFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQ
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHH
EQFPQELHETYLNFIKEYLATKYVDFIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
QDYRDPDTGEIFDRALLNLELEKIEKPAGISNPKDFRNEVVNFVLRARANNRGKNPVWNS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
YEKLKSVIEKKMFTNTEDLLPVISFNAKASEEDKKKHEEFISRMVEKGYTRKQVRLLCEW
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YLRVRKSQ
HHHHHCCC
>Mature Secondary Structure
MLLYRKEKKKNHIISFSGLSKRGWRMNTQDFLAGYTKRFVDNKEEDMSLDEYLELCKTDP
CCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCCC
TAYANPAERLLMAIGEPELIDTRHDPVLSRIFSNKIIHHYEVFKDFYGMEEPIEQIVGFL
CCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KHAAQGLEETKQVLYLLGPVGGGKSSIAEKLKDLMERIPFYAIKGSPVFESPLSLFNPLE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHCHHHHHCCCC
DGELLRERFGIPTRYLRYLMSPWAVKRLQEYNGDISKFRVIKVKPSRLKQIAIAKTEPGD
CHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCHHHEEEEEECHHHHHHHHEECCCCCC
ENNQDISSLVGKVDIRKLEEFSQDDPDAYSYSGGLCRANRGLLEFVEMFKAPIKVLHPLL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHH
TATQEGNYNATEGLSAIPFEGIILAHSNESEWQSFRNNKNNEAFIDRINIVKVPYCLRVS
HHCCCCCCCHHCCCCCCCCCCEEEEECCHHHHHHHHCCCCCHHHHHHHHEEECCHHHHHH
EEIKIYQKLIHNSSLANAPCAPGTLDMLAQFSVLTRLKEPQNSSIYSKMRVYNGESLKDT
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCC
DPKAKSYQEYRDFAGVDEGMSGISTRFAFKILSKVFNFDHTEVAANPVHLMYVLERQIEQ
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHH
EQFPQELHETYLNFIKEYLATKYVDFIGKEIQTAYLESYSEYGQNIFDRYITYADFWIQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
QDYRDPDTGEIFDRALLNLELEKIEKPAGISNPKDFRNEVVNFVLRARANNRGKNPVWNS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
YEKLKSVIEKKMFTNTEDLLPVISFNAKASEEDKKKHEEFISRMVEKGYTRKQVRLLCEW
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YLRVRKSQ
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]