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The map label for this gene is hda [H]

Identifier: 52842998

GI number: 52842998

Start: 3156673

End: 3157410

Strand: Direct

Name: hda [H]

Synonym: lpg2802

Alternate gene names: 52842998

Gene position: 3156673-3157410 (Clockwise)

Preceding gene: 52842997

Following gene: 52842999

Centisome position: 92.9

GC content: 37.4

Gene sequence:

>738_bases
TTGGACCTGGAGCAGAAAAGCCTGGTCCCCCAAAGAATCGTAAAAATGAATAAACAGCTGGCCCTGGCAATAAAATTGAA
TGATGAAGCAACCCTGGACGACTTCAATTGGGGTAATAATACCTTGTTGCAGCAGCAATTAATTGAAATGCTTTCTTTTA
AGGCAGACAGGTTGCTCTATCTTTGGGGCCCTAAAGGAAGTGGCAAATCACATTTACTGCAAGCTTGTTGCCAAGCCATT
AATTTAACCCAATCAGCCATTTACCTTCCTTTAGCTTTTTTAAAAGAATGGGGACCACAAAGCATTGAAGGATTAGAAGA
TCAAACTTTAATTTGTATTGATGATATTAATACCATCGCTAACGATTCGGCCTGGGAAGAAGCTTTATTCCATTTATATA
ATAAGATTAAGGACTCCGAACGTTCTCTTTTAATTATATCAGGTAATCAACCACCAATAAAATGTGACATTAAACTTGCG
GATTTACGCTCCAGACTAAGTTGGGGATTAGTTATTCAGTTGAATGAATTAAACGATGACGAAAAAATAAACACACTCAA
AATGCGCGCAGCAAAACGCGGATTTGAACTTCCTGAGAGTGTCGGACATTTTTTATTAAACCGTTGCTCTCGAAACATGC
ATGATTTATATGAGATCCTCAACCAGCTAGATGATGCATCTTGGGAGGCTCATCGTAAAATCACCATACCTTTTGTTAAA
AATATTTTGAAAATATAA

Upstream 100 bases:

>100_bases
GTTTATTTGAATTAGCTTACTTTAGATTCCCCTATGATTTAGTTGATATACTCATCTATTTAACTGCCTTTACCACCGTT
ACTTCCTACCTTGATTATGT

Downstream 100 bases:

>100_bases
GAGGTTATTGACTCTCCCTTATAAATTTATTTAAGATCCTTGATGAGGAACCACCGTAATTCTTTTATCATTCCCCATAT
ATTGCCTATCCACAGAGTTA

Product: DnaA-like family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MDLEQKSLVPQRIVKMNKQLALAIKLNDEATLDDFNWGNNTLLQQQLIEMLSFKADRLLYLWGPKGSGKSHLLQACCQAI
NLTQSAIYLPLAFLKEWGPQSIEGLEDQTLICIDDINTIANDSAWEEALFHLYNKIKDSERSLLIISGNQPPIKCDIKLA
DLRSRLSWGLVIQLNELNDDEKINTLKMRAAKRGFELPESVGHFLLNRCSRNMHDLYEILNQLDDASWEAHRKITIPFVK
NILKI

Sequences:

>Translated_245_residues
MDLEQKSLVPQRIVKMNKQLALAIKLNDEATLDDFNWGNNTLLQQQLIEMLSFKADRLLYLWGPKGSGKSHLLQACCQAI
NLTQSAIYLPLAFLKEWGPQSIEGLEDQTLICIDDINTIANDSAWEEALFHLYNKIKDSERSLLIISGNQPPIKCDIKLA
DLRSRLSWGLVIQLNELNDDEKINTLKMRAAKRGFELPESVGHFLLNRCSRNMHDLYEILNQLDDASWEAHRKITIPFVK
NILKI
>Mature_245_residues
MDLEQKSLVPQRIVKMNKQLALAIKLNDEATLDDFNWGNNTLLQQQLIEMLSFKADRLLYLWGPKGSGKSHLLQACCQAI
NLTQSAIYLPLAFLKEWGPQSIEGLEDQTLICIDDINTIANDSAWEEALFHLYNKIKDSERSLLIISGNQPPIKCDIKLA
DLRSRLSWGLVIQLNELNDDEKINTLKMRAAKRGFELPESVGHFLLNRCSRNMHDLYEILNQLDDASWEAHRKITIPFVK
NILKI

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=228, Percent_Identity=44.2982456140351, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI2367267, Length=234, Percent_Identity=23.5042735042735, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 28069; Mature: 28069

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEQKSLVPQRIVKMNKQLALAIKLNDEATLDDFNWGNNTLLQQQLIEMLSFKADRLLY
CCCCHHHCCHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEE
LWGPKGSGKSHLLQACCQAINLTQSAIYLPLAFLKEWGPQSIEGLEDQTLICIDDINTIA
EECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEECCHHHC
NDSAWEEALFHLYNKIKDSERSLLIISGNQPPIKCDIKLADLRSRLSWGLVIQLNELNDD
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEHHHHHHHCCCCEEEEEECCCCC
EKINTLKMRAAKRGFELPESVGHFLLNRCSRNMHDLYEILNQLDDASWEAHRKITIPFVK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCEEEHHHHH
NILKI
HHHCC
>Mature Secondary Structure
MDLEQKSLVPQRIVKMNKQLALAIKLNDEATLDDFNWGNNTLLQQQLIEMLSFKADRLLY
CCCCHHHCCHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEE
LWGPKGSGKSHLLQACCQAINLTQSAIYLPLAFLKEWGPQSIEGLEDQTLICIDDINTIA
EECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHCCCCCCEEEEEECCHHHC
NDSAWEEALFHLYNKIKDSERSLLIISGNQPPIKCDIKLADLRSRLSWGLVIQLNELNDD
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEHHHHHHHCCCCEEEEEECCCCC
EKINTLKMRAAKRGFELPESVGHFLLNRCSRNMHDLYEILNQLDDASWEAHRKITIPFVK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCEEEHHHHH
NILKI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA