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The map label for this gene is hit

Identifier: 52842964

GI number: 52842964

Start: 3115727

End: 3116068

Strand: Direct

Name: hit

Synonym: lpg2765

Alternate gene names: 52842964

Gene position: 3115727-3116068 (Clockwise)

Preceding gene: 52842959

Following gene: 52842965

Centisome position: 91.7

GC content: 37.43

Gene sequence:

>342_bases
ATGAATTGTTTGTTTTGCAAAATTGCACAGGGTGAAATTCCTGCAACAGTAGTTTTTGAAGACAAAAATATTTTGGCATT
TCGCGATATTAGACCTCAAGCACCAACACATTTATTGATTATACCCAAAAAGCATATTGCAACTATCAATGATGTGAACG
ATGATGATAGCGAACTTCTTGCTAATATTCTAATAAGAGCAAAAAAATTAGCACAGGCCGAAGGACTAAGTGAAATGGGT
TATCGATTGGTTTTTAATGTTAATTCTGGTGGCGGGCAGGAAGTTTACCACATTCATTTACATTTACTTGGCGGGCGTCA
AATGACTTGGCCGCCAGGTTAG

Upstream 100 bases:

>100_bases
ATATTATGCGAAAAATCGCATCAAAAGGCAAAGACAAGCGTTCGCAATATAATAAATGAAATGTATAATAGCATTTTGAA
TCTAAAACATCGGATGACCT

Downstream 100 bases:

>100_bases
GAATTCTTGCTATGGAAAAATTATACTCAAATTTGCTTAAAGAATTAGGCGAAGATATAAATCGGGAAGGATTAAAGGAT
ACTCCTGGACGAGCAGCTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MNCLFCKIAQGEIPATVVFEDKNILAFRDIRPQAPTHLLIIPKKHIATINDVNDDDSELLANILIRAKKLAQAEGLSEMG
YRLVFNVNSGGGQEVYHIHLHLLGGRQMTWPPG

Sequences:

>Translated_113_residues
MNCLFCKIAQGEIPATVVFEDKNILAFRDIRPQAPTHLLIIPKKHIATINDVNDDDSELLANILIRAKKLAQAEGLSEMG
YRLVFNVNSGGGQEVYHIHLHLLGGRQMTWPPG
>Mature_113_residues
MNCLFCKIAQGEIPATVVFEDKNILAFRDIRPQAPTHLLIIPKKHIATINDVNDDDSELLANILIRAKKLAQAEGLSEMG
YRLVFNVNSGGGQEVYHIHLHLLGGRQMTWPPG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=112, Percent_Identity=58.0357142857143, Blast_Score=138, Evalue=9e-34,
Organism=Homo sapiens, GI14211923, Length=111, Percent_Identity=49.5495495495495, Blast_Score=124, Evalue=1e-29,
Organism=Homo sapiens, GI189217863, Length=106, Percent_Identity=30.188679245283, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787346, Length=105, Percent_Identity=53.3333333333333, Blast_Score=113, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17506713, Length=112, Percent_Identity=47.3214285714286, Blast_Score=122, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320078, Length=115, Percent_Identity=40, Blast_Score=76, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574010, Length=112, Percent_Identity=48.2142857142857, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24581222, Length=112, Percent_Identity=48.2142857142857, Blast_Score=119, Evalue=3e-28,
Organism=Drosophila melanogaster, GI85724830, Length=111, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 12572; Mature: 12572

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCLFCKIAQGEIPATVVFEDKNILAFRDIRPQAPTHLLIIPKKHIATINDVNDDDSELL
CCEEEEEEECCCCCEEEEECCCCEEEEECCCCCCCEEEEEECHHHEEEECCCCCCHHHHH
ANILIRAKKLAQAEGLSEMGYRLVFNVNSGGGQEVYHIHLHLLGGRQMTWPPG
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCCEECCCCC
>Mature Secondary Structure
MNCLFCKIAQGEIPATVVFEDKNILAFRDIRPQAPTHLLIIPKKHIATINDVNDDDSELL
CCEEEEEEECCCCCEEEEECCCCEEEEECCCCCCCEEEEEECHHHEEEECCCCCCHHHHH
ANILIRAKKLAQAEGLSEMGYRLVFNVNSGGGQEVYHIHLHLLGGRQMTWPPG
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEEEECCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]