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The map label for this gene is nahR [H]

Identifier: 52842611

GI number: 52842611

Start: 2714053

End: 2714973

Strand: Reverse

Name: nahR [H]

Synonym: lpg2402

Alternate gene names: 52842611

Gene position: 2714973-2714053 (Counterclockwise)

Preceding gene: 52842612

Following gene: 52842608

Centisome position: 79.9

GC content: 38.55

Gene sequence:

>921_bases
ATGGCGATTCCCTTTAAACGTATTAATTTAAATCTCATACTACATCTGGATGCTTTACTAAGCGAGAGAAGCGTCAGTGC
TGCTGCAGAGAAAGTGTTTGTCAGCCAACCAGCCATGAGTTCCTCTTTAAAACAACTGAGAGAGTTATTTAAAGACCCGC
TATTAATTCCTGGTAAAGGGGAATATTTTCTCTCTCCAAAAGCTAAAGAGTTGCAGCCACAATTAGAGCAAGTGATGTTT
TTCATAAGAAATATTCTGCAACCGAATGAGCGATTTGATCCCTTTCAGACCAAAAGATCATTTAAAATCGCTTTACCTGA
TTACGTTGAATTAATTTTGTTGCCATCCCTGATGGCGGCGCTTGAAAAACTGCCTCATATTGTTATTGAGACAACGATTC
AATCAATGGCTGATGATCCACATCTGTTTATCGATGAGAATGTAGATCTGGCGATTGGAGCTATTAATGAAAATTCTCTA
TCCGCGCAACTCAAAGTTGAAAAACTGTATGAGGAGGAAATTATTTGTTTTGCAAGCAAAAACAATCCACTCATAAACAG
GCCATTGTCTTTGGAAGATTACATAAGCAATAAACATATCGCATTTAGTTTTAATCAGGAGCGTTATAGCCACTCCGCTG
AATATTTATATAAAAGAAAGCTGGTACGTAATGACATGCTTTTTGTAAAAAATATCTTGCCCGCAATTTTCGCAGTAGCC
AATTCCGATGCGGTGATTTCCACAGCCCCAAGTTTTTTGATAAATATGTTTGCCAGACAGTTTAATCTGGGAATGCAACC
TTTACCTTTCAATCTGGAACCAACTCCTATTTATCTGGTGACCCATAGCAAAAGTCAGTATGATGAGGGAGTCTCCTGGT
TAGCCAAGCTGGTCAGTTCAAGCATTAAAAGTCCATCCTGA

Upstream 100 bases:

>100_bases
TCTCAAAACACACTCTGTCATTGATAATGAATTATCCATATTGGATGCTTTTAAATTTCTTATACTAATATAAGAAGAGA
ACAATTGCCGAGAGGATCGA

Downstream 100 bases:

>100_bases
AGTATAAGTCTCGATTGAGGAAGTATCTGATTTTTCTGTCTCCTTCTTTATCTCAACCGGCTCATCCTGAATGGAAGTAT
CAGGAGAGCTATCAGAGCTA

Product: regulatory protein (LysR transcriptional regulator)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MAIPFKRINLNLILHLDALLSERSVSAAAEKVFVSQPAMSSSLKQLRELFKDPLLIPGKGEYFLSPKAKELQPQLEQVMF
FIRNILQPNERFDPFQTKRSFKIALPDYVELILLPSLMAALEKLPHIVIETTIQSMADDPHLFIDENVDLAIGAINENSL
SAQLKVEKLYEEEIICFASKNNPLINRPLSLEDYISNKHIAFSFNQERYSHSAEYLYKRKLVRNDMLFVKNILPAIFAVA
NSDAVISTAPSFLINMFARQFNLGMQPLPFNLEPTPIYLVTHSKSQYDEGVSWLAKLVSSSIKSPS

Sequences:

>Translated_306_residues
MAIPFKRINLNLILHLDALLSERSVSAAAEKVFVSQPAMSSSLKQLRELFKDPLLIPGKGEYFLSPKAKELQPQLEQVMF
FIRNILQPNERFDPFQTKRSFKIALPDYVELILLPSLMAALEKLPHIVIETTIQSMADDPHLFIDENVDLAIGAINENSL
SAQLKVEKLYEEEIICFASKNNPLINRPLSLEDYISNKHIAFSFNQERYSHSAEYLYKRKLVRNDMLFVKNILPAIFAVA
NSDAVISTAPSFLINMFARQFNLGMQPLPFNLEPTPIYLVTHSKSQYDEGVSWLAKLVSSSIKSPS
>Mature_305_residues
AIPFKRINLNLILHLDALLSERSVSAAAEKVFVSQPAMSSSLKQLRELFKDPLLIPGKGEYFLSPKAKELQPQLEQVMFF
IRNILQPNERFDPFQTKRSFKIALPDYVELILLPSLMAALEKLPHIVIETTIQSMADDPHLFIDENVDLAIGAINENSLS
AQLKVEKLYEEEIICFASKNNPLINRPLSLEDYISNKHIAFSFNQERYSHSAEYLYKRKLVRNDMLFVKNILPAIFAVAN
SDAVISTAPSFLINMFARQFNLGMQPLPFNLEPTPIYLVTHSKSQYDEGVSWLAKLVSSSIKSPS

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=305, Percent_Identity=23.2786885245902, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34744; Mature: 34613

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPFKRINLNLILHLDALLSERSVSAAAEKVFVSQPAMSSSLKQLRELFKDPLLIPGKG
CCCCCEEECEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEECCCC
EYFLSPKAKELQPQLEQVMFFIRNILQPNERFDPFQTKRSFKIALPDYVELILLPSLMAA
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEECHHHHHHHHHHHHHHH
LEKLPHIVIETTIQSMADDPHLFIDENVDLAIGAINENSLSAQLKVEKLYEEEIICFASK
HHHCCHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
NNPLINRPLSLEDYISNKHIAFSFNQERYSHSAEYLYKRKLVRNDMLFVKNILPAIFAVA
CCCCCCCCCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NSDAVISTAPSFLINMFARQFNLGMQPLPFNLEPTPIYLVTHSKSQYDEGVSWLAKLVSS
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SIKSPS
HCCCCC
>Mature Secondary Structure 
AIPFKRINLNLILHLDALLSERSVSAAAEKVFVSQPAMSSSLKQLRELFKDPLLIPGKG
CCCCEEECEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEECCCC
EYFLSPKAKELQPQLEQVMFFIRNILQPNERFDPFQTKRSFKIALPDYVELILLPSLMAA
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEECHHHHHHHHHHHHHHH
LEKLPHIVIETTIQSMADDPHLFIDENVDLAIGAINENSLSAQLKVEKLYEEEIICFASK
HHHCCHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
NNPLINRPLSLEDYISNKHIAFSFNQERYSHSAEYLYKRKLVRNDMLFVKNILPAIFAVA
CCCCCCCCCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NSDAVISTAPSFLINMFARQFNLGMQPLPFNLEPTPIYLVTHSKSQYDEGVSWLAKLVSS
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SIKSPS
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]