Click here to switch to the map view.

The map label for this gene is fabG

Identifier: 52842444

GI number: 52842444

Start: 2523344

End: 2524096

Strand: Direct

Name: fabG

Synonym: lpg2231

Alternate gene names: 52842444

Gene position: 2523344-2524096 (Clockwise)

Preceding gene: 52842443

Following gene: 52842445

Centisome position: 74.27

GC content: 40.64

Gene sequence:

>753_bases
ATGAATATCCTTATTACTGGCGGCTCCTCTGATATTGCCCAAGCCATAGCGAAACGACGCAGTGAATCAGGCGATAAGAT
CATCATTACCTGCTCTAATGACATCAGTCTTAATCAAACTCTCGCAATATACCGCCAACAGAACATTGACGTGACGGGTT
TCATTTATAACTTTTCAGATCCTCAAGCTTGTGAGGCCGATTTGGAATTGATTTTAAAAGAACCACTCGATGGCATCATA
TTAAATGCGTTCACTCGGGTCACCCAACTGCGTAAATTACATGCATTGCCCTATCACGCTGTTCGTACTTACCTGGATAA
CAATCTCAATGGCAACATTTGGCTTATTCATCGTTTATTACCTGCCTTGCTAAAAAATAAATTTGGGCGACTAGTCCTCA
TTTCAAGTCTTTCAGCAACAGCTGGCACCAGTCGATATCCGGTTTATTGTACGGCAAAGGCTGCTCTAGAAGGATTATTT
TTTAATTTGGCTGTTGATTATAGTGCTAACAATATCTTGTCTAATATAGTACGCGTAGGCTTAATTAAAACCTCCAGAAC
AGAGCAATTTTGGAAAAATCCAGCCTATCAAGAAAAAGTAATACAAATTATTCCACAGGGCACTATGGGTGAACCAACTC
AAGTTGCGGAAGCCATTGATCCACTTTTGTCAAAAACCTCGTTTATGACGGGATCAGTTGTAACAGTCAGTGGTGGTCTG
CCTTTAATGCGTTCAGAAGGATTGTTGTCATGA

Upstream 100 bases:

>100_bases
AACGTGAATTTGAAATTAAAATCCCTGTCATTCCACTCGAGAAAGAACATTACGAATCGATCAATACTATTGAACAATAC
CTCATTGAGCTGGGGGCAAA

Downstream 100 bases:

>100_bases
ATTTTTTCCGTTGTGAAAAACCCATCTATATAAAAGGCCCTTTTGTTGCGCTTCCCGAGAGAATCATGAGCAACCAAGAT
GTTCTCAATTGGATGAACAG

Product: 3-oxoacyl reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDISLNQTLAIYRQQNIDVTGFIYNFSDPQACEADLELILKEPLDGII
LNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLLPALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLF
FNLAVDYSANNILSNIVRVGLIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
PLMRSEGLLS

Sequences:

>Translated_250_residues
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDISLNQTLAIYRQQNIDVTGFIYNFSDPQACEADLELILKEPLDGII
LNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLLPALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLF
FNLAVDYSANNILSNIVRVGLIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
PLMRSEGLLS
>Mature_250_residues
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDISLNQTLAIYRQQNIDVTGFIYNFSDPQACEADLELILKEPLDGII
LNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLLPALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLF
FNLAVDYSANNILSNIVRVGLIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
PLMRSEGLLS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=25.3112033195021, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=24.4897959183673, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=27.8688524590164, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=24.8979591836735, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=25.3112033195021, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=25.3061224489796, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=24.7933884297521, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=27.1966527196653, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27472; Mature: 27472

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDISLNQTLAIYRQQNIDVTGFIYNFSD
CEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEEECCC
PQACEADLELILKEPLDGIILNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEHHHHH
PALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLFFNLAVDYSANNILSNIVRVG
HHHHHCCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHEEEEEEEECCHHHHHHHHHHHH
LIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
HHCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PLMRSEGLLS
CCCCCCCCCC
>Mature Secondary Structure
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDISLNQTLAIYRQQNIDVTGFIYNFSD
CEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEEECCC
PQACEADLELILKEPLDGIILNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEHHHHH
PALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLFFNLAVDYSANNILSNIVRVG
HHHHHCCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHEEEEEEEECCHHHHHHHHHHHH
LIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPTQVAEAIDPLLSKTSFMTGSVVTVSGGL
HHCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PLMRSEGLLS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]