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The map label for this gene is arcB [H]

Identifier: 52842393

GI number: 52842393

Start: 2451717

End: 2454203

Strand: Direct

Name: arcB [H]

Synonym: lpg2180

Alternate gene names: 52842393

Gene position: 2451717-2454203 (Clockwise)

Preceding gene: 52842392

Following gene: 52842394

Centisome position: 72.16

GC content: 33.17

Gene sequence:

>2487_bases
ATGCCTAAAAAAGCGGATCTGACATTGCTCCTCATCAATACCCTTGAAGAACCAATATTTTATCTTTCCTCAGATTTTAT
TATTTTAGATCTCAACGCTTCCGCCAAGAAAATATTCAAAATTACAAAGAATTCAATTATTGGAAAACCTTTTTCAGTTT
TATGTTCTGATCATGATTTAAAATCACTTGAACATCCTTTTGATAGAAATTTAAAGACATATATTAGAAAAAAAATAGTT
TTATGGGATTCATTATGTTTAAAAAAGCCTATAAATGGAATTCAATATATTGCTATAGGGACTATTAAAAATCAAACCAA
TAAATCCGCATTGAATAGCAATCTCAAAACAAACACAGATGGCACCAACCCTATAGACATCACAAGTAAATTTTTAACGG
AACAAATAAATAATAAAAGTAAAAATACTTCAGATTATGTATATGCTATTTATCGCTACATGGAAAATATTATCGCACAG
ATTCCAGTAAGTGTTTATTGGATGAATAAAAATCATGTGTACATGGGGTGTAGCAATAATATGGTTAAATTATTAAATCT
CAATTCAAGGTACGATATTGTTGGTAAAACTTACGAGGATCTATATCACGAAAAATCAACCTCATACTATAAAAAAGCAG
ATAAAATAGTTATGGATAAAGGTATCTCATTAAGTCTGGAAGAGCCATTCTATTGTCCCGATGGAACTACTAAAGAGATT
TATTTGTCGAATAAAGTCCCTCTTCGTGACCTGGAGGGTAAAATTATAGGTATGCTCGGGGTATCAGTAGATATTACTGA
TAGAAAAAAAATGGAGTTGGAACTTAGTAAAGCTAAAGAAGCTGCTGAGGAAGCAAACAATGTAAAGACTGAATTCATAG
CCAATATGAGCCATGATCTCAGAACCCCACTAAGTGGTGTTGTGGGTATGGCTGAACTTATGAAAGAGCAAGTAACAGAT
CCTGTACAAGTACAATATGCGGAGTGGATTTTTGATTGCAGCCAACAATTATTGAGTTTATTAGATGGCATACTTGACAT
CGTATCCTTGGGAAATGTTAAAGAAGATGAATTAAAAATAACAACCTTTGACATCAACGAATGTATTGCGGAATTAGTTC
ATCTTGAAATGCCGTCCATTAAACTGAAACAACTTGATTTGATCGTTAATATTGATAAAAAGATTCCTCGATTAATAAAA
ACCGACCGTATAAAACTTCATCGAATTATTCTCAATCTTTTAGGTAATGCCATTAAATTTACCGATTCCGGTTATATTGC
AATTGATGTGAAATTACTTGAGCTAAATAATGAGTCAGGATTAATTTATTTTGCAATATCTGATACTGGCATTGGTATCC
CCGAAAATCAACAAACGAAAATATTTGACAGATTTCATCGTATTATCCCGTCCAGCATAGGAAAATATAAAGGCCATGGC
GTTGGTTTACATATTGTTCAATCCTATGTAAACCTGCTAGGCGGAGAAATACAGGTAAACAGTGAACCGGGAGTAGGAAC
TACCTTTTATTTTGAACTCCCTATTCAAATTGAAAAAGAAAATGAAGTGATAAAGGGTCATTATAAGCTTGAAAAAAAAA
ATATAATACCTGTACCTAAAAAAGAAAAAATTTTAGATAAAAACTCAAAAAATGAGTTTTTGTATAACTCACCTAATATT
CTCATCCTGGAAGATAATCTGGTAGCCAGACGTACAATAGAAAGCTTGGCGACTCAAGAAAAATGTCGTTTTGTTTCTGT
AGCAAAAGGTAAAGAAGCCATACGGCTTGCTAAAACCAATGAATTTGATCTGATAATCACAGATATTGGGTTACCAGATA
TTGAAGGACATGTGGTAGCAAAATTAATTAGAGAATGGGAGTTATCTCAATCAAAGCCACCGATACCAATAATAGGATTA
ACTGCACATGTCAAAGAAAAATCCAAAGAAATATGCTTGAAATCAGGTATGGATGATGTATTCAACAAACCAATCAGTCG
GCAGCTTTTACAGTATATACTGAGTCGATTCATTCCATCAAAAAATAAAAACTCAACTTCATGCTCTTCTCAAAAGACAA
CATCATCAGAGCAAATAATAGAAGCAGATTTGCCAGAAAGTGAAAGTAATTTTTTTAACTTGGACTCTTATCCTTTACTC
GATATTCACAATGCTGTTTCCATCATGGGTAGTCTCAAATTGGTTCGGGAGATATTACCACTTATGATAGGTGAAGAAAC
CCAAAAAGATGTTGAATCCATTGAAAAAGCTTTTCATATAAAAGATTGGGAAACGGTAGAGAGAATCGCTCATAAAATGA
AGGGTGGTGCTGCGAATTGCGGTGCTGTACGTATGAAATATGCTTGCCAATATTTAGAGCGCTATCAAAAGATGGGATAT
ACCAAGCTTCTTGAGCCTCTTTACCAACAACTTATAAAAGTCGTGGAAGATACCCAAAAGAATATTCATGAATGGCTAAA
ACATTGA

Upstream 100 bases:

>100_bases
ACAGAGGTTTTGGTTGATTTGTTTCTTCTCTCTCCGTGACCTATTATTTAAATGGAATAAATAAAATCCATATGAATGAA
ATTGAATTAGGTCACTCTCT

Downstream 100 bases:

>100_bases
CCCTCACTAGAAACATCAATGGTATTCACTAATTAAGCCCCCAGAAAAAACTTCAAATATAATATTTATCAATCAACTTG
AATATTATAAATACACATTA

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 828; Mature: 827

Protein sequence:

>828_residues
MPKKADLTLLLINTLEEPIFYLSSDFIILDLNASAKKIFKITKNSIIGKPFSVLCSDHDLKSLEHPFDRNLKTYIRKKIV
LWDSLCLKKPINGIQYIAIGTIKNQTNKSALNSNLKTNTDGTNPIDITSKFLTEQINNKSKNTSDYVYAIYRYMENIIAQ
IPVSVYWMNKNHVYMGCSNNMVKLLNLNSRYDIVGKTYEDLYHEKSTSYYKKADKIVMDKGISLSLEEPFYCPDGTTKEI
YLSNKVPLRDLEGKIIGMLGVSVDITDRKKMELELSKAKEAAEEANNVKTEFIANMSHDLRTPLSGVVGMAELMKEQVTD
PVQVQYAEWIFDCSQQLLSLLDGILDIVSLGNVKEDELKITTFDINECIAELVHLEMPSIKLKQLDLIVNIDKKIPRLIK
TDRIKLHRIILNLLGNAIKFTDSGYIAIDVKLLELNNESGLIYFAISDTGIGIPENQQTKIFDRFHRIIPSSIGKYKGHG
VGLHIVQSYVNLLGGEIQVNSEPGVGTTFYFELPIQIEKENEVIKGHYKLEKKNIIPVPKKEKILDKNSKNEFLYNSPNI
LILEDNLVARRTIESLATQEKCRFVSVAKGKEAIRLAKTNEFDLIITDIGLPDIEGHVVAKLIREWELSQSKPPIPIIGL
TAHVKEKSKEICLKSGMDDVFNKPISRQLLQYILSRFIPSKNKNSTSCSSQKTTSSEQIIEADLPESESNFFNLDSYPLL
DIHNAVSIMGSLKLVREILPLMIGEETQKDVESIEKAFHIKDWETVERIAHKMKGGAANCGAVRMKYACQYLERYQKMGY
TKLLEPLYQQLIKVVEDTQKNIHEWLKH

Sequences:

>Translated_828_residues
MPKKADLTLLLINTLEEPIFYLSSDFIILDLNASAKKIFKITKNSIIGKPFSVLCSDHDLKSLEHPFDRNLKTYIRKKIV
LWDSLCLKKPINGIQYIAIGTIKNQTNKSALNSNLKTNTDGTNPIDITSKFLTEQINNKSKNTSDYVYAIYRYMENIIAQ
IPVSVYWMNKNHVYMGCSNNMVKLLNLNSRYDIVGKTYEDLYHEKSTSYYKKADKIVMDKGISLSLEEPFYCPDGTTKEI
YLSNKVPLRDLEGKIIGMLGVSVDITDRKKMELELSKAKEAAEEANNVKTEFIANMSHDLRTPLSGVVGMAELMKEQVTD
PVQVQYAEWIFDCSQQLLSLLDGILDIVSLGNVKEDELKITTFDINECIAELVHLEMPSIKLKQLDLIVNIDKKIPRLIK
TDRIKLHRIILNLLGNAIKFTDSGYIAIDVKLLELNNESGLIYFAISDTGIGIPENQQTKIFDRFHRIIPSSIGKYKGHG
VGLHIVQSYVNLLGGEIQVNSEPGVGTTFYFELPIQIEKENEVIKGHYKLEKKNIIPVPKKEKILDKNSKNEFLYNSPNI
LILEDNLVARRTIESLATQEKCRFVSVAKGKEAIRLAKTNEFDLIITDIGLPDIEGHVVAKLIREWELSQSKPPIPIIGL
TAHVKEKSKEICLKSGMDDVFNKPISRQLLQYILSRFIPSKNKNSTSCSSQKTTSSEQIIEADLPESESNFFNLDSYPLL
DIHNAVSIMGSLKLVREILPLMIGEETQKDVESIEKAFHIKDWETVERIAHKMKGGAANCGAVRMKYACQYLERYQKMGY
TKLLEPLYQQLIKVVEDTQKNIHEWLKH
>Mature_827_residues
PKKADLTLLLINTLEEPIFYLSSDFIILDLNASAKKIFKITKNSIIGKPFSVLCSDHDLKSLEHPFDRNLKTYIRKKIVL
WDSLCLKKPINGIQYIAIGTIKNQTNKSALNSNLKTNTDGTNPIDITSKFLTEQINNKSKNTSDYVYAIYRYMENIIAQI
PVSVYWMNKNHVYMGCSNNMVKLLNLNSRYDIVGKTYEDLYHEKSTSYYKKADKIVMDKGISLSLEEPFYCPDGTTKEIY
LSNKVPLRDLEGKIIGMLGVSVDITDRKKMELELSKAKEAAEEANNVKTEFIANMSHDLRTPLSGVVGMAELMKEQVTDP
VQVQYAEWIFDCSQQLLSLLDGILDIVSLGNVKEDELKITTFDINECIAELVHLEMPSIKLKQLDLIVNIDKKIPRLIKT
DRIKLHRIILNLLGNAIKFTDSGYIAIDVKLLELNNESGLIYFAISDTGIGIPENQQTKIFDRFHRIIPSSIGKYKGHGV
GLHIVQSYVNLLGGEIQVNSEPGVGTTFYFELPIQIEKENEVIKGHYKLEKKNIIPVPKKEKILDKNSKNEFLYNSPNIL
ILEDNLVARRTIESLATQEKCRFVSVAKGKEAIRLAKTNEFDLIITDIGLPDIEGHVVAKLIREWELSQSKPPIPIIGLT
AHVKEKSKEICLKSGMDDVFNKPISRQLLQYILSRFIPSKNKNSTSCSSQKTTSSEQIIEADLPESESNFFNLDSYPLLD
IHNAVSIMGSLKLVREILPLMIGEETQKDVESIEKAFHIKDWETVERIAHKMKGGAANCGAVRMKYACQYLERYQKMGYT
KLLEPLYQQLIKVVEDTQKNIHEWLKH

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=652, Percent_Identity=27.3006134969325, Blast_Score=222, Evalue=9e-59,
Organism=Escherichia coli, GI87081816, Length=537, Percent_Identity=25.3258845437616, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1788713, Length=523, Percent_Identity=26.0038240917782, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1789149, Length=254, Percent_Identity=38.5826771653543, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=33.4630350194552, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1788549, Length=326, Percent_Identity=25.4601226993865, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=28.0487804878049, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=27.7056277056277, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1790861, Length=262, Percent_Identity=28.2442748091603, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786600, Length=267, Percent_Identity=23.5955056179775, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=258, Percent_Identity=23.6434108527132, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=25.8620689655172, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1788393, Length=256, Percent_Identity=23.828125, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 94150; Mature: 94019

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKADLTLLLINTLEEPIFYLSSDFIILDLNASAKKIFKITKNSIIGKPFSVLCSDHDL
CCCCCCEEEEEEHHHHHHHHEECCCEEEEECCCCHHHHHHHHHHCCCCCCHHEEECCCCH
KSLEHPFDRNLKTYIRKKIVLWDSLCLKKPINGIQYIAIGTIKNQTNKSALNSNLKTNTD
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHCCCCCCCCC
GTNPIDITSKFLTEQINNKSKNTSDYVYAIYRYMENIIAQIPVSVYWMNKNHVYMGCSNN
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCC
MVKLLNLNSRYDIVGKTYEDLYHEKSTSYYKKADKIVMDKGISLSLEEPFYCPDGTTKEI
EEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHEECCCCEEECCCCEECCCCCCCEE
YLSNKVPLRDLEGKIIGMLGVSVDITDRKKMELELSKAKEAAEEANNVKTEFIANMSHDL
EEECCCCCHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHH
RTPLSGVVGMAELMKEQVTDPVQVQYAEWIFDCSQQLLSLLDGILDIVSLGNVKEDELKI
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TTFDINECIAELVHLEMPSIKLKQLDLIVNIDKKIPRLIKTDRIKLHRIILNLLGNAIKF
EEEEHHHHHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
TDSGYIAIDVKLLELNNESGLIYFAISDTGIGIPENQQTKIFDRFHRIIPSSIGKYKGHG
CCCCEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
VGLHIVQSYVNLLGGEIQVNSEPGVGTTFYFELPIQIEKENEVIKGHYKLEKKNIIPVPK
CHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEECCCCCEEECEEEECCCCCCCCCC
KEKILDKNSKNEFLYNSPNILILEDNLVARRTIESLATQEKCRFVSVAKGKEAIRLAKTN
CHHHHCCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEECC
EFDLIITDIGLPDIEGHVVAKLIREWELSQSKPPIPIIGLTAHVKEKSKEICLKSGMDDV
CCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHH
FNKPISRQLLQYILSRFIPSKNKNSTSCSSQKTTSSEQIIEADLPESESNFFNLDSYPLL
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEECCCCCCCCCEECCCCCCEE
DIHNAVSIMGSLKLVREILPLMIGEETQKDVESIEKAFHIKDWETVERIAHKMKGGAANC
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
GAVRMKYACQYLERYQKMGYTKLLEPLYQQLIKVVEDTQKNIHEWLKH
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKKADLTLLLINTLEEPIFYLSSDFIILDLNASAKKIFKITKNSIIGKPFSVLCSDHDL
CCCCCEEEEEEHHHHHHHHEECCCEEEEECCCCHHHHHHHHHHCCCCCCHHEEECCCCH
KSLEHPFDRNLKTYIRKKIVLWDSLCLKKPINGIQYIAIGTIKNQTNKSALNSNLKTNTD
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHCCCCCCCCC
GTNPIDITSKFLTEQINNKSKNTSDYVYAIYRYMENIIAQIPVSVYWMNKNHVYMGCSNN
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCC
MVKLLNLNSRYDIVGKTYEDLYHEKSTSYYKKADKIVMDKGISLSLEEPFYCPDGTTKEI
EEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHEECCCCEEECCCCEECCCCCCCEE
YLSNKVPLRDLEGKIIGMLGVSVDITDRKKMELELSKAKEAAEEANNVKTEFIANMSHDL
EEECCCCCHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHH
RTPLSGVVGMAELMKEQVTDPVQVQYAEWIFDCSQQLLSLLDGILDIVSLGNVKEDELKI
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TTFDINECIAELVHLEMPSIKLKQLDLIVNIDKKIPRLIKTDRIKLHRIILNLLGNAIKF
EEEEHHHHHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
TDSGYIAIDVKLLELNNESGLIYFAISDTGIGIPENQQTKIFDRFHRIIPSSIGKYKGHG
CCCCEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
VGLHIVQSYVNLLGGEIQVNSEPGVGTTFYFELPIQIEKENEVIKGHYKLEKKNIIPVPK
CHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEECCCCCEEECEEEECCCCCCCCCC
KEKILDKNSKNEFLYNSPNILILEDNLVARRTIESLATQEKCRFVSVAKGKEAIRLAKTN
CHHHHCCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEECC
EFDLIITDIGLPDIEGHVVAKLIREWELSQSKPPIPIIGLTAHVKEKSKEICLKSGMDDV
CCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHH
FNKPISRQLLQYILSRFIPSKNKNSTSCSSQKTTSSEQIIEADLPESESNFFNLDSYPLL
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEECCCCCCCCCEECCCCCCEE
DIHNAVSIMGSLKLVREILPLMIGEETQKDVESIEKAFHIKDWETVERIAHKMKGGAANC
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
GAVRMKYACQYLERYQKMGYTKLLEPLYQQLIKVVEDTQKNIHEWLKH
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]