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The map label for this gene is tycC [H]

Identifier: 52842392

GI number: 52842392

Start: 2447235

End: 2451596

Strand: Direct

Name: tycC [H]

Synonym: lpg2179

Alternate gene names: 52842392

Gene position: 2447235-2451596 (Clockwise)

Preceding gene: 52842391

Following gene: 52842393

Centisome position: 72.03

GC content: 34.69

Gene sequence:

>4362_bases
GTGGCTTTTATTAATCGATCCAGTCTGACAGCATGGAGCACTATGATTAAAAGCAAGACATTTAGTTGCTATATTATCGG
TGAAGCTAATATAACTCTTCAATGTGCAGATATCCTATTAGCAGGAGGCCATAAATTACTTGGCATAATCTCTCCATCAA
ACACCATAAAAAAATGGTGTACTGCCAATTCCATTGCTTATCTTGAGAACATCAAGGAATTTGAAAAAAATCATATGGAC
GAAGAATTTGATTTCTTGTTTAGCATAGTCAACAGTGAAATCATTCCTCAAAAAATTTTAAGACTCCCTCGTTATTACGC
CATAAACTATCATAACTCCCCATTACCCAAATATGCAGGATTATATGCCACTTCGTGGGCGATCCTTAATGGCGAAACTC
AGCATGGTATTAGTTGGCACATTATGAATGAAGTGATAGATGCAGGTGATATTCTAAAGCAACCAACTTTTCCAATAAAT
GATCTGGATACGGCGTTTAGTTTAAATCTGAAATGTTATGAACAAGGGATCTATTCCTTTCATGAACTTGTTGAAGAGCT
TTCATCCCACACTACGACTTCGGTTAAACAAAATCTGTCATGCCGTTCTTATTATGGTCTAAAAAACAAGCCGGCAAATT
TTGGATTTATTTCATGGGAAGAATCTTCAGAAAGCATTGATCGGCTCTGCAGGGCTTTAACATTTGGAAATTATACCAAT
CAGTTAGAAGTACCCAAGATTATGATTAATAAGGAAATTTATGTTGTAAAATCTTATGAAAAATTAAATATATCCTCAGG
AGTAAAACCAGGCACCGTTGTGAATAACTCGAATGGTGGCTTACAAGTAGCTACCGGAACAACAGATATATTGATTCTAG
AGCTTACTGATCTTGAGGGCAGAACATGCTCAATGGAAGAATTAGGCAGCTTATTTAAAATGACTCGCTACTCACAACTT
GACACAATTGAACCTGCGTTTTTTGAAAAGCTAACAATTTGTCCTGCTAAAAAACCAAAAATAGAGAAGTTCTGGGTCAA
TGAGTTTTTGAAATGTGCTCAAGAAAAGAATTCATTTTTATCTCCACTATCCCAACTCGATAAAACATCATGTTCACTTC
ACGATAGAAAAACAGTAACACAAGTACCTGGTGAGTTACTCGCAAAATTGAAAAAACTATGCCCTGAGCATTGGCAAATA
AAGAATATCTTATTAACTAGCCTCTTAATTTACCTATATCGATTAAATAATTACAGTAATCTCTCGATTGCATTCATTAA
TTCACAATTGAGCAGTAATGATCCTGATTTAAATAAGCTTTTATCAGACTATGTGCCTTTAACAACGCAATTTGATAGCA
CTATGACATTTATGGACGCATTGACATTTGTCTCAAAAGAACAGGGAAAGTTATATGAAAACAGCACTTACACTAGAGAT
ATTTTCATACGCTACCCTGAGCTACATAATGCTTTCAACCATATTGATGTCAGTATCACCTATATTACTGACTCAAAAGC
AGTGGCACCTTGTGTCGGCGATAAAAAGTTAAACTTCTGTATTGCAGAGGATTGTTCCTGGTTTTATGTTAATAATAAAA
CAAATTATAGAGCCCATTTGGAATCTTATGCTTTTTTTGAAAATATGAATGAGCATTTGCTGACTTTATTGGAAGATATA
GTCAGTAACCCTGATAAAAAGATATTCGAACTTTCAATAATCAGTAAAAAGGAAAAAAACGATTTATTGGTAGTCTGGAA
TAACACTCAGTGTGATTACGATTATGAAAAACCGATTCATCAATATTTTGAAGAGCAAGTTTCCAAAACACCTGACGAAA
TAGCTGCTGTCTTTGAGAACAAATCAATAACTTATGTAGAACTTAACCGAAAAGCCAATCAATTAGCACACTATTTAAGA
TCTCAAGGTGTAAAACAAGATGACCTGGTAGGGATTTCTTTAAGTCGCAGTTTGGAAATGGTTATATGCATTTTAGGCAT
TTTAAAGTCTGGAGGAGCTTACCTGCCATTAGATCCTAATTATCCTGATGAGCGGATTTCATACATGCTAATGGACAGTA
AAACTAACCTGCTGATAACAGATCAAGAATTCATAAAGAGAAAACCACATGGATTCAATGGCAAAAGTATTGAGATAAAT
TCCTTTTTAAATTTAAAAAACCTGTCTTCTGAAAATCTTCAAGCAATTAACAAACCATCCGATTTAGCCTACATTATTTA
TACTTCCGGGACTACAGGAAAACCTAAAGGTGTAGCCATATCGCATCGTTCTATTTGCAATCACATGTTGTGGATGAAGA
AGGAATACGCTTTTAAAAACAAGGATGTATTTTTACAGAAAACCCCCTTCTCGTTTGATGCCTCTGTTTGGGAGTTTTTT
ATGCCACTTCTGGTTGGTGGTAAACTGGTCGTTGCCCCAAATGATGCACATACCAGTCCCAATCAAATGATACGCCTAAT
CAGAGAGAACAAAGTTAGCGTATTGCAGATCGTTCCTTCTATGCTAAAAGAATTAGTATCTAACGAAGAGTTTGGTCTCT
GCAAATCACTCACGCATGTATTTTGTGGTGGTGAAGCCCTTTTATCAGAAACAATTAATGCTTTTTTTAAGTACAACTTC
TCAGATACAAAACTACATAATCTCTATGGACCAACGGAAGTAACCATTGATACAACTGCTTATACATGTACCGCAGGAGA
TGCAAAAGGCGATGTAAGCCGAATAGGCAAACCGATAATGAACACAAAAGTGTATGTATTAGATGCAAAAATGCAGCCTG
TTCCTATTGGAATAATGGGGGAGCTTTATATTTCAGGAGATGGTTTAGCACGTGGTTATTTAAACAACCCTGAATTTACC
ATACAGAAATTTTTACCCAACCCATTCAGCAACAATAAAAATGATCGATTATACAGAACAGGGGATCTTGTCAAATGGAA
TTCCAACGGAGTCCTGGAATATCACGGCCGATGTGATAATCAAGTAAAAATTAGAGGATATAGGATAGAAATCAATGAAA
TTGAATCCTATTTGGAAAAAATTCCTTCCATCCATCAATGCATTGTGAAACCGGAAAAAAACCAGGACGACTCAATGTCT
TTATCAGCTTATTTGGTTTTGGAAAAAAATTCTCAAATATCCGCTGTAGATATTCGGGCTATATTAAAGCAGAATATTCC
TGAATACATGATCCCGGCCCGATTTTATATTGTTGACAAATTTTTTAGCACCCCAAGCGGTAAAATAGATAGAAAAATGT
TACCAATCCCATCCAAACGATTACGTTCGGGTACTAATTATGCTCCCCCCAATAATCCTAAAGAACAATTATTACACAAT
ATCTGGTGTTCGGTTTTAAAAATAGATAATTTGGGAATTTACGATGATTTTTTCGAACTTGGCGGTAATTCACTATCAGC
AATGAACATAATATCACATATACGGGAACAATTTTCACTGACATTGAGCGTTAGAACATTATTTGATTTTCCCACAATAT
CCTCTTTATCTAAAGCAATAGAGAACATATACCATAAGAAGACTGATTGTATATACAATCAGTCTTCTGGAAATCATATC
ATCCCTCTTAGAACAGAAGGAGAAAAAACACCTCTGTTTTTAGTACATCCAATTGGTGGAAGTGTTTTTTGGTACAAACT
TCTTGGACAATATTTTGATAAAGATAGACCATTGTATGGAATACAGGATCCTGGGCTTGATAGAAATGAATTGATATTTA
GTAACCTGGAAGAAATGGCTAGTGCATATGTCCATTCAATTCAGGCTATTCAACCAAGCGGACCTTACATACTTGGTGGC
GCATCATTTGGATGTACTGTTGCTATTGAAATGGCGAAACAATTAGAGGAAAAAGGAGAAACAGTAATTTCTATTATCTC
CCTTGATGGTTGGGCATTTTACCCTTCCTTACAAAACAATGAGCTTTATTTTCAAGAAGTTATGAAAGAACAAAATTCAA
GAATTCTAAAGAAATATATTGAAAATAACGTCAGTAACTCCAAATTTTTATTAGAATTACAATGGCATAGAGAAAACATG
TTGACTCAATATAAAATGCCAATTATTAAACCCAAATTTATTTTATTTAAGGCAAAAAAACTTACAGAAATGTTTCAATA
TAATGCTAGTTTGAATTGGTGGGAAAATTATACAAGTCAACCAATTGAACTACATTTAACTCCTGGTGATCATGAAAGCA
TGTTTTATGAGCCTAATATCAAAATCCTGGCTACCAAGCTCAATGATAGCTTAAATGAGCAGGATATTAAGCATTACCAA
TTCAATGATACACTGAAGGATTCATTTATAGATCAACTCTAA

Upstream 100 bases:

>100_bases
CCCTTAATATATTTATGCACTCGGTTCCTCTCTTCTTTGCATGATGTCGTGAGTGAAATTTTAATCAACCTTGACTAAAA
AAGATCATTTCAATTAAAAT

Downstream 100 bases:

>100_bases
ACCAGTATCATCAGAACTGCACAGAGGTTTTGGTTGATTTGTTTCTTCTCTCTCCGTGACCTATTATTTAAATGGAATAA
ATAAAATCCATATGAATGAA

Product: peptide synthetase, non-ribosomal

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 1453; Mature: 1452

Protein sequence:

>1453_residues
MAFINRSSLTAWSTMIKSKTFSCYIIGEANITLQCADILLAGGHKLLGIISPSNTIKKWCTANSIAYLENIKEFEKNHMD
EEFDFLFSIVNSEIIPQKILRLPRYYAINYHNSPLPKYAGLYATSWAILNGETQHGISWHIMNEVIDAGDILKQPTFPIN
DLDTAFSLNLKCYEQGIYSFHELVEELSSHTTTSVKQNLSCRSYYGLKNKPANFGFISWEESSESIDRLCRALTFGNYTN
QLEVPKIMINKEIYVVKSYEKLNISSGVKPGTVVNNSNGGLQVATGTTDILILELTDLEGRTCSMEELGSLFKMTRYSQL
DTIEPAFFEKLTICPAKKPKIEKFWVNEFLKCAQEKNSFLSPLSQLDKTSCSLHDRKTVTQVPGELLAKLKKLCPEHWQI
KNILLTSLLIYLYRLNNYSNLSIAFINSQLSSNDPDLNKLLSDYVPLTTQFDSTMTFMDALTFVSKEQGKLYENSTYTRD
IFIRYPELHNAFNHIDVSITYITDSKAVAPCVGDKKLNFCIAEDCSWFYVNNKTNYRAHLESYAFFENMNEHLLTLLEDI
VSNPDKKIFELSIISKKEKNDLLVVWNNTQCDYDYEKPIHQYFEEQVSKTPDEIAAVFENKSITYVELNRKANQLAHYLR
SQGVKQDDLVGISLSRSLEMVICILGILKSGGAYLPLDPNYPDERISYMLMDSKTNLLITDQEFIKRKPHGFNGKSIEIN
SFLNLKNLSSENLQAINKPSDLAYIIYTSGTTGKPKGVAISHRSICNHMLWMKKEYAFKNKDVFLQKTPFSFDASVWEFF
MPLLVGGKLVVAPNDAHTSPNQMIRLIRENKVSVLQIVPSMLKELVSNEEFGLCKSLTHVFCGGEALLSETINAFFKYNF
SDTKLHNLYGPTEVTIDTTAYTCTAGDAKGDVSRIGKPIMNTKVYVLDAKMQPVPIGIMGELYISGDGLARGYLNNPEFT
IQKFLPNPFSNNKNDRLYRTGDLVKWNSNGVLEYHGRCDNQVKIRGYRIEINEIESYLEKIPSIHQCIVKPEKNQDDSMS
LSAYLVLEKNSQISAVDIRAILKQNIPEYMIPARFYIVDKFFSTPSGKIDRKMLPIPSKRLRSGTNYAPPNNPKEQLLHN
IWCSVLKIDNLGIYDDFFELGGNSLSAMNIISHIREQFSLTLSVRTLFDFPTISSLSKAIENIYHKKTDCIYNQSSGNHI
IPLRTEGEKTPLFLVHPIGGSVFWYKLLGQYFDKDRPLYGIQDPGLDRNELIFSNLEEMASAYVHSIQAIQPSGPYILGG
ASFGCTVAIEMAKQLEEKGETVISIISLDGWAFYPSLQNNELYFQEVMKEQNSRILKKYIENNVSNSKFLLELQWHRENM
LTQYKMPIIKPKFILFKAKKLTEMFQYNASLNWWENYTSQPIELHLTPGDHESMFYEPNIKILATKLNDSLNEQDIKHYQ
FNDTLKDSFIDQL

Sequences:

>Translated_1453_residues
MAFINRSSLTAWSTMIKSKTFSCYIIGEANITLQCADILLAGGHKLLGIISPSNTIKKWCTANSIAYLENIKEFEKNHMD
EEFDFLFSIVNSEIIPQKILRLPRYYAINYHNSPLPKYAGLYATSWAILNGETQHGISWHIMNEVIDAGDILKQPTFPIN
DLDTAFSLNLKCYEQGIYSFHELVEELSSHTTTSVKQNLSCRSYYGLKNKPANFGFISWEESSESIDRLCRALTFGNYTN
QLEVPKIMINKEIYVVKSYEKLNISSGVKPGTVVNNSNGGLQVATGTTDILILELTDLEGRTCSMEELGSLFKMTRYSQL
DTIEPAFFEKLTICPAKKPKIEKFWVNEFLKCAQEKNSFLSPLSQLDKTSCSLHDRKTVTQVPGELLAKLKKLCPEHWQI
KNILLTSLLIYLYRLNNYSNLSIAFINSQLSSNDPDLNKLLSDYVPLTTQFDSTMTFMDALTFVSKEQGKLYENSTYTRD
IFIRYPELHNAFNHIDVSITYITDSKAVAPCVGDKKLNFCIAEDCSWFYVNNKTNYRAHLESYAFFENMNEHLLTLLEDI
VSNPDKKIFELSIISKKEKNDLLVVWNNTQCDYDYEKPIHQYFEEQVSKTPDEIAAVFENKSITYVELNRKANQLAHYLR
SQGVKQDDLVGISLSRSLEMVICILGILKSGGAYLPLDPNYPDERISYMLMDSKTNLLITDQEFIKRKPHGFNGKSIEIN
SFLNLKNLSSENLQAINKPSDLAYIIYTSGTTGKPKGVAISHRSICNHMLWMKKEYAFKNKDVFLQKTPFSFDASVWEFF
MPLLVGGKLVVAPNDAHTSPNQMIRLIRENKVSVLQIVPSMLKELVSNEEFGLCKSLTHVFCGGEALLSETINAFFKYNF
SDTKLHNLYGPTEVTIDTTAYTCTAGDAKGDVSRIGKPIMNTKVYVLDAKMQPVPIGIMGELYISGDGLARGYLNNPEFT
IQKFLPNPFSNNKNDRLYRTGDLVKWNSNGVLEYHGRCDNQVKIRGYRIEINEIESYLEKIPSIHQCIVKPEKNQDDSMS
LSAYLVLEKNSQISAVDIRAILKQNIPEYMIPARFYIVDKFFSTPSGKIDRKMLPIPSKRLRSGTNYAPPNNPKEQLLHN
IWCSVLKIDNLGIYDDFFELGGNSLSAMNIISHIREQFSLTLSVRTLFDFPTISSLSKAIENIYHKKTDCIYNQSSGNHI
IPLRTEGEKTPLFLVHPIGGSVFWYKLLGQYFDKDRPLYGIQDPGLDRNELIFSNLEEMASAYVHSIQAIQPSGPYILGG
ASFGCTVAIEMAKQLEEKGETVISIISLDGWAFYPSLQNNELYFQEVMKEQNSRILKKYIENNVSNSKFLLELQWHRENM
LTQYKMPIIKPKFILFKAKKLTEMFQYNASLNWWENYTSQPIELHLTPGDHESMFYEPNIKILATKLNDSLNEQDIKHYQ
FNDTLKDSFIDQL
>Mature_1452_residues
AFINRSSLTAWSTMIKSKTFSCYIIGEANITLQCADILLAGGHKLLGIISPSNTIKKWCTANSIAYLENIKEFEKNHMDE
EFDFLFSIVNSEIIPQKILRLPRYYAINYHNSPLPKYAGLYATSWAILNGETQHGISWHIMNEVIDAGDILKQPTFPIND
LDTAFSLNLKCYEQGIYSFHELVEELSSHTTTSVKQNLSCRSYYGLKNKPANFGFISWEESSESIDRLCRALTFGNYTNQ
LEVPKIMINKEIYVVKSYEKLNISSGVKPGTVVNNSNGGLQVATGTTDILILELTDLEGRTCSMEELGSLFKMTRYSQLD
TIEPAFFEKLTICPAKKPKIEKFWVNEFLKCAQEKNSFLSPLSQLDKTSCSLHDRKTVTQVPGELLAKLKKLCPEHWQIK
NILLTSLLIYLYRLNNYSNLSIAFINSQLSSNDPDLNKLLSDYVPLTTQFDSTMTFMDALTFVSKEQGKLYENSTYTRDI
FIRYPELHNAFNHIDVSITYITDSKAVAPCVGDKKLNFCIAEDCSWFYVNNKTNYRAHLESYAFFENMNEHLLTLLEDIV
SNPDKKIFELSIISKKEKNDLLVVWNNTQCDYDYEKPIHQYFEEQVSKTPDEIAAVFENKSITYVELNRKANQLAHYLRS
QGVKQDDLVGISLSRSLEMVICILGILKSGGAYLPLDPNYPDERISYMLMDSKTNLLITDQEFIKRKPHGFNGKSIEINS
FLNLKNLSSENLQAINKPSDLAYIIYTSGTTGKPKGVAISHRSICNHMLWMKKEYAFKNKDVFLQKTPFSFDASVWEFFM
PLLVGGKLVVAPNDAHTSPNQMIRLIRENKVSVLQIVPSMLKELVSNEEFGLCKSLTHVFCGGEALLSETINAFFKYNFS
DTKLHNLYGPTEVTIDTTAYTCTAGDAKGDVSRIGKPIMNTKVYVLDAKMQPVPIGIMGELYISGDGLARGYLNNPEFTI
QKFLPNPFSNNKNDRLYRTGDLVKWNSNGVLEYHGRCDNQVKIRGYRIEINEIESYLEKIPSIHQCIVKPEKNQDDSMSL
SAYLVLEKNSQISAVDIRAILKQNIPEYMIPARFYIVDKFFSTPSGKIDRKMLPIPSKRLRSGTNYAPPNNPKEQLLHNI
WCSVLKIDNLGIYDDFFELGGNSLSAMNIISHIREQFSLTLSVRTLFDFPTISSLSKAIENIYHKKTDCIYNQSSGNHII
PLRTEGEKTPLFLVHPIGGSVFWYKLLGQYFDKDRPLYGIQDPGLDRNELIFSNLEEMASAYVHSIQAIQPSGPYILGGA
SFGCTVAIEMAKQLEEKGETVISIISLDGWAFYPSLQNNELYFQEVMKEQNSRILKKYIENNVSNSKFLLELQWHRENML
TQYKMPIIKPKFILFKAKKLTEMFQYNASLNWWENYTSQPIELHLTPGDHESMFYEPNIKILATKLNDSLNEQDIKHYQF
NDTLKDSFIDQL

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=613, Percent_Identity=23.9804241435563, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI187761345, Length=536, Percent_Identity=24.0671641791045, Blast_Score=113, Evalue=2e-24,
Organism=Homo sapiens, GI187761343, Length=536, Percent_Identity=24.0671641791045, Blast_Score=113, Evalue=2e-24,
Organism=Homo sapiens, GI42544132, Length=530, Percent_Identity=23.0188679245283, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI38505220, Length=557, Percent_Identity=22.8007181328546, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI122937307, Length=506, Percent_Identity=23.5177865612648, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI156151445, Length=550, Percent_Identity=22, Blast_Score=84, Evalue=8e-16,
Organism=Escherichia coli, GI1786801, Length=983, Percent_Identity=31.8413021363174, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1786810, Length=524, Percent_Identity=28.2442748091603, Blast_Score=134, Evalue=4e-32,
Organism=Escherichia coli, GI145693145, Length=530, Percent_Identity=22.6415094339623, Blast_Score=120, Evalue=9e-28,
Organism=Escherichia coli, GI221142682, Length=502, Percent_Identity=23.3067729083665, Blast_Score=114, Evalue=7e-26,
Organism=Escherichia coli, GI1790505, Length=555, Percent_Identity=22.1621621621622, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1788107, Length=572, Percent_Identity=21.3286713286713, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI1789201, Length=382, Percent_Identity=23.2984293193717, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1789683, Length=307, Percent_Identity=22.4755700325733, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788589, Length=352, Percent_Identity=21.875, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=839, Percent_Identity=24.9106078665077, Blast_Score=191, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17556356, Length=638, Percent_Identity=27.8996865203762, Blast_Score=169, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17557194, Length=542, Percent_Identity=24.3542435424354, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32563687, Length=507, Percent_Identity=22.0907297830375, Blast_Score=100, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17538037, Length=545, Percent_Identity=24.0366972477064, Blast_Score=98, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994694, Length=538, Percent_Identity=21.3754646840149, Blast_Score=97, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71994703, Length=538, Percent_Identity=21.3754646840149, Blast_Score=97, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994690, Length=542, Percent_Identity=21.5867158671587, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534440, Length=535, Percent_Identity=23.3644859813084, Blast_Score=91, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551278, Length=534, Percent_Identity=22.2846441947566, Blast_Score=90, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17559526, Length=544, Percent_Identity=22.4264705882353, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71996755, Length=477, Percent_Identity=22.6415094339623, Blast_Score=88, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32564422, Length=418, Percent_Identity=23.444976076555, Blast_Score=86, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564420, Length=418, Percent_Identity=23.444976076555, Blast_Score=86, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560140, Length=531, Percent_Identity=21.4689265536723, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560308, Length=557, Percent_Identity=20.6463195691203, Blast_Score=84, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17531443, Length=538, Percent_Identity=21.1895910780669, Blast_Score=83, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=730, Percent_Identity=26.4383561643836, Blast_Score=245, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6319699, Length=486, Percent_Identity=22.4279835390947, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648676, Length=680, Percent_Identity=29.4117647058824, Blast_Score=256, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24581924, Length=545, Percent_Identity=24.0366972477064, Blast_Score=115, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21356441, Length=536, Percent_Identity=24.2537313432836, Blast_Score=97, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24582852, Length=591, Percent_Identity=23.0118443316413, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21355181, Length=514, Percent_Identity=23.1517509727626, Blast_Score=91, Evalue=7e-18,
Organism=Drosophila melanogaster, GI161076582, Length=546, Percent_Identity=20.8791208791209, Blast_Score=88, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24653035, Length=534, Percent_Identity=20.7865168539326, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281364798, Length=472, Percent_Identity=23.3050847457627, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583465, Length=472, Percent_Identity=23.3050847457627, Blast_Score=83, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583463, Length=472, Percent_Identity=23.3050847457627, Blast_Score=83, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356947, Length=497, Percent_Identity=20.1207243460765, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 165947; Mature: 165816

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFINRSSLTAWSTMIKSKTFSCYIIGEANITLQCADILLAGGHKLLGIISPSNTIKKWC
CCEECCCCHHHHHHHHHCCCEEEEEEECCCEEEEEEEEHEECCCEEEEEECCCHHHHHHH
TANSIAYLENIKEFEKNHMDEEFDFLFSIVNSEIIPQKILRLPRYYAINYHNSPLPKYAG
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCCCCHHHC
LYATSWAILNGETQHGISWHIMNEVIDAGDILKQPTFPINDLDTAFSLNLKCYEQGIYSF
CEEEEEEEECCCCCCCEEHEEHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHH
HELVEELSSHTTTSVKQNLSCRSYYGLKNKPANFGFISWEESSESIDRLCRALTFGNYTN
HHHHHHHHCCCHHHHHHCCCHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
QLEVPKIMINKEIYVVKSYEKLNISSGVKPGTVVNNSNGGLQVATGTTDILILELTDLEG
CCCCCEEEECCEEEEEECCCEECCCCCCCCCEEEECCCCCEEEEECCCEEEEEEEECCCC
RTCSMEELGSLFKMTRYSQLDTIEPAFFEKLTICPAKKPKIEKFWVNEFLKCAQEKNSFL
CEECHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
SPLSQLDKTSCSLHDRKTVTQVPGELLAKLKKLCPEHWQIKNILLTSLLIYLYRLNNYSN
HHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
LSIAFINSQLSSNDPDLNKLLSDYVPLTTQFDSTMTFMDALTFVSKEQGKLYENSTYTRD
EEEEEEECCCCCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCCEECCCCEEEE
IFIRYPELHNAFNHIDVSITYITDSKAVAPCVGDKKLNFCIAEDCSWFYVNNKTNYRAHL
EEEECCHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHH
ESYAFFENMNEHLLTLLEDIVSNPDKKIFELSIISKKEKNDLLVVWNNTQCDYDYEKPIH
HHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHH
QYFEEQVSKTPDEIAAVFENKSITYVELNRKANQLAHYLRSQGVKQDDLVGISLSRSLEM
HHHHHHHHCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
VICILGILKSGGAYLPLDPNYPDERISYMLMDSKTNLLITDQEFIKRKPHGFNGKSIEIN
HHHHHHHHHCCCEEECCCCCCCHHHEEEEEEECCCCEEEECHHHHHCCCCCCCCCEEEEE
SFLNLKNLSSENLQAINKPSDLAYIIYTSGTTGKPKGVAISHRSICNHMLWMKKEYAFKN
CEEECCCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCC
KDVFLQKTPFSFDASVWEFFMPLLVGGKLVVAPNDAHTSPNQMIRLIRENKVSVLQIVPS
CCEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHH
MLKELVSNEEFGLCKSLTHVFCGGEALLSETINAFFKYNFSDTKLHNLYGPTEVTIDTTA
HHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCEECCCCCCEEEEEECCE
YTCTAGDAKGDVSRIGKPIMNTKVYVLDAKMQPVPIGIMGELYISGDGLARGYLNNPEFT
EEEECCCCCCCHHHCCCHHHCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCEE
IQKFLPNPFSNNKNDRLYRTGDLVKWNSNGVLEYHGRCDNQVKIRGYRIEINEIESYLEK
HHHHCCCCCCCCCCCCEEECCCEEEECCCCEEEECCCCCCEEEEEEEEEEHHHHHHHHHH
IPSIHQCIVKPEKNQDDSMSLSAYLVLEKNSQISAVDIRAILKQNIPEYMIPARFYIVDK
CCCHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEHHHHHHHHHHCCCCHHCCCCEEEEEH
FFSTPSGKIDRKMLPIPSKRLRSGTNYAPPNNPKEQLLHNIWCSVLKIDNLGIYDDFFEL
HHCCCCCCCCCEECCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHC
GGNSLSAMNIISHIREQFSLTLSVRTLFDFPTISSLSKAIENIYHKKTDCIYNQSSGNHI
CCCCHHHHHHHHHHHHHHEEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHCEEECCCCCEE
IPLRTEGEKTPLFLVHPIGGSVFWYKLLGQYFDKDRPLYGIQDPGLDRNELIFSNLEEMA
EEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHH
SAYVHSIQAIQPSGPYILGGASFGCTVAIEMAKQLEEKGETVISIISLDGWAFYPSLQNN
HHHHHHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCEEECCCCCCC
ELYFQEVMKEQNSRILKKYIENNVSNSKFLLELQWHRENMLTQYKMPIIKPKFILFKAKK
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHCCCCCCCEEEEEEHHH
LTEMFQYNASLNWWENYTSQPIELHLTPGDHESMFYEPNIKILATKLNDSLNEQDIKHYQ
HHHHHHHCCCCCHHHCCCCCCEEEEECCCCCCCEEECCCCEEEEEECCCCCCHHHCCEEE
FNDTLKDSFIDQL
CCCHHHHHHHHCC
>Mature Secondary Structure 
AFINRSSLTAWSTMIKSKTFSCYIIGEANITLQCADILLAGGHKLLGIISPSNTIKKWC
CEECCCCHHHHHHHHHCCCEEEEEEECCCEEEEEEEEHEECCCEEEEEECCCHHHHHHH
TANSIAYLENIKEFEKNHMDEEFDFLFSIVNSEIIPQKILRLPRYYAINYHNSPLPKYAG
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCCCCHHHC
LYATSWAILNGETQHGISWHIMNEVIDAGDILKQPTFPINDLDTAFSLNLKCYEQGIYSF
CEEEEEEEECCCCCCCEEHEEHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHH
HELVEELSSHTTTSVKQNLSCRSYYGLKNKPANFGFISWEESSESIDRLCRALTFGNYTN
HHHHHHHHCCCHHHHHHCCCHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCC
QLEVPKIMINKEIYVVKSYEKLNISSGVKPGTVVNNSNGGLQVATGTTDILILELTDLEG
CCCCCEEEECCEEEEEECCCEECCCCCCCCCEEEECCCCCEEEEECCCEEEEEEEECCCC
RTCSMEELGSLFKMTRYSQLDTIEPAFFEKLTICPAKKPKIEKFWVNEFLKCAQEKNSFL
CEECHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
SPLSQLDKTSCSLHDRKTVTQVPGELLAKLKKLCPEHWQIKNILLTSLLIYLYRLNNYSN
HHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
LSIAFINSQLSSNDPDLNKLLSDYVPLTTQFDSTMTFMDALTFVSKEQGKLYENSTYTRD
EEEEEEECCCCCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCCEECCCCEEEE
IFIRYPELHNAFNHIDVSITYITDSKAVAPCVGDKKLNFCIAEDCSWFYVNNKTNYRAHL
EEEECCHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHH
ESYAFFENMNEHLLTLLEDIVSNPDKKIFELSIISKKEKNDLLVVWNNTQCDYDYEKPIH
HHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHH
QYFEEQVSKTPDEIAAVFENKSITYVELNRKANQLAHYLRSQGVKQDDLVGISLSRSLEM
HHHHHHHHCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
VICILGILKSGGAYLPLDPNYPDERISYMLMDSKTNLLITDQEFIKRKPHGFNGKSIEIN
HHHHHHHHHCCCEEECCCCCCCHHHEEEEEEECCCCEEEECHHHHHCCCCCCCCCEEEEE
SFLNLKNLSSENLQAINKPSDLAYIIYTSGTTGKPKGVAISHRSICNHMLWMKKEYAFKN
CEEECCCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCC
KDVFLQKTPFSFDASVWEFFMPLLVGGKLVVAPNDAHTSPNQMIRLIRENKVSVLQIVPS
CCEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHH
MLKELVSNEEFGLCKSLTHVFCGGEALLSETINAFFKYNFSDTKLHNLYGPTEVTIDTTA
HHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCEECCCCCCEEEEEECCE
YTCTAGDAKGDVSRIGKPIMNTKVYVLDAKMQPVPIGIMGELYISGDGLARGYLNNPEFT
EEEECCCCCCCHHHCCCHHHCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCEE
IQKFLPNPFSNNKNDRLYRTGDLVKWNSNGVLEYHGRCDNQVKIRGYRIEINEIESYLEK
HHHHCCCCCCCCCCCCEEECCCEEEECCCCEEEECCCCCCEEEEEEEEEEHHHHHHHHHH
IPSIHQCIVKPEKNQDDSMSLSAYLVLEKNSQISAVDIRAILKQNIPEYMIPARFYIVDK
CCCHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEHHHHHHHHHHCCCCHHCCCCEEEEEH
FFSTPSGKIDRKMLPIPSKRLRSGTNYAPPNNPKEQLLHNIWCSVLKIDNLGIYDDFFEL
HHCCCCCCCCCEECCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCHHHHHHC
GGNSLSAMNIISHIREQFSLTLSVRTLFDFPTISSLSKAIENIYHKKTDCIYNQSSGNHI
CCCCHHHHHHHHHHHHHHEEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHCEEECCCCCEE
IPLRTEGEKTPLFLVHPIGGSVFWYKLLGQYFDKDRPLYGIQDPGLDRNELIFSNLEEMA
EEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHH
SAYVHSIQAIQPSGPYILGGASFGCTVAIEMAKQLEEKGETVISIISLDGWAFYPSLQNN
HHHHHHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCEEECCCCCCC
ELYFQEVMKEQNSRILKKYIENNVSNSKFLLELQWHRENMLTQYKMPIIKPKFILFKAKK
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHCCCCCCCEEEEEEHHH
LTEMFQYNASLNWWENYTSQPIELHLTPGDHESMFYEPNIKILATKLNDSLNEQDIKHYQ
HHHHHHHCCCCCHHHCCCCCCEEEEECCCCCCCEEECCCCEEEEEECCCCCCHHHCCEEE
FNDTLKDSFIDQL
CCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]