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The map label for this gene is argS

Identifier: 52842248

GI number: 52842248

Start: 2272934

End: 2274703

Strand: Reverse

Name: argS

Synonym: lpg2031

Alternate gene names: 52842248

Gene position: 2274703-2272934 (Counterclockwise)

Preceding gene: 52842249

Following gene: 52842247

Centisome position: 66.95

GC content: 41.36

Gene sequence:

>1770_bases
ATGAGAAGTATGAAAGCTATAATCGAATATCTTTTGAAACAGGCATTAATTAATCTGCAACAATCAGGCGAAATGCCAAT
TGATTTGGAGATTGAAATAAAAGTTGAGAATGCCAAAGATCCAGCTCATGGTGATTATGCGACTAATTTGGCTCTGGTAT
TAGCTAAACCATGCCGACAAGCACCTAAAGTATTAGCCGAGCGATTGGTTGCAGTAATCCCCGTAGATCCGTCTGTAGAG
AAAATTGAGATAGCTGGGGCAGGATTTATTAATTTTTTCATGCGCAGCACGGCACGCTCGCTCATCATTTCTGAAATTTT
GAATAAAGGCAAGGAGTTTGGCCGAGGTAATTTAGGACAGAGCCAAAAAGTATTGATTGAATTTGTTTCTGCCAATCCAA
CAGGGCCTTTACATGTAGGACATGGAAGAGGGGCTGCTTTCGGAGCAACTTTGGGTAATGTTTTAAAAGCCGCTGGTTAC
GATGTGACTTTGGAATATTATGTCAATGATGCAGGCAGGCAAATGAATATTCTCGCTGTGAGTGTGTGGCTGCGCTACCT
GGAATTGGCAGGTGAGCCAATTGTTTTTCCGGCGAATGGCTATAAAGGTCAATATGTTTATGAGATTGCACAAGAGATTT
GGTCAGAGCAGGGTAATCAATTCGTGCATCCATGGATTTCGGTAGTAGAAAATTTACCTGCTGATGAACCCGAAGGTGGA
GATAAAGAGACTTATATCGATGCGATCATCGCGCGAGCGCAATCCTTACTGGGCAAGGATGGGTTTGCTAATTTCCATCA
ACATGCTTTAAAAACGGTATTGGATGATATAAAAGATGATTTGCAGGCGTTTGGTGTTCGTTTTGACAGTTGGTTTTCTG
AGCAATCGTTATTTGAAGATGGTTCTATTGAGAAAGGTATTCAGGCCTTGAAAGATAGAGGCCACACTTATGAAAGAGAA
GGTGCTTTATGGTTTAGGGCAACTGATTTTGGTGATGAAAAAGATAGAGTATTAGTCCGGGCTAATGGGCAAACGACATA
TTTCGCTTCTGATGTAGCTTATCACTGGAATAAATATGATAGAGGTTTTGATCGAGTAATTGATATTTTTGGTGCTGATC
ATCATGGTTATGTCACGAGAATCAAAACAGCTGTTAAGGCATTAGGACATGATGAAAGTGCATTGGATGTCATTTTGGTG
CAGTTTGCCATTCTGTATCGAGGTGGTGACAGGGTGCAAATGTCTACTCGCAGTGGTTCATTTGTTACTTTGAGAGAGCT
AAGAGAAGAAGTAGGAAATGATGCGGCTCGTTATTTTTATGTGGCAAGAAAACCTGAACAACACATGGATTTTGACCTGG
ATCTGGCAAAGTCCGAATCCAGTGACAATCCTGTGTATTATATTCAATATGCACATGCCCGTATCTGTAGTGTATTGAGA
CAGTTAAAAGAAAGGGGTTTGAAGTGGGATAAGGATATGGGACTTAAAAACCTTGATTTATTGGAGCAACAACATGAGGC
CACATTAATTTCTCTGATTGCCCGATATCCCGAAGTCATTCAATCTGCCGCCGCTTCTTGCGAGCCGCATCAGCTTGCTT
ACTATTTAAGAGAGCTAGCCAATGGGTTACACAGTTATTATAATGCGATCCAGCTATTATGTGAGCAAGAACAATTGCGA
TGTGCCCGTTTGTGTTTGCTGGAGTCGGTTCGACAGGTTTTAAATAATGGTTTGGCTATACTAGGCGTATCAGCTCCTGA
GAGTATGTGA

Upstream 100 bases:

>100_bases
GCTATTGCTGTTTCTATTGTTGTAATGATGGTGCTGCGGGGTTGAGAGCCTTTCCATATGGTATGAAAAAGAGCATAATA
TCGGTATTTTTGACGGATAA

Downstream 100 bases:

>100_bases
TGGCAAAAGATTATGGAAATAGACGTGCTGCACGTCGCAACAGAGGACCGCACCAGTTTTTGGTTATTATTGTGACCTTT
TTGTTTGGATATATAACTGC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MRSMKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPKVLAERLVAVIPVDPSVE
KIEIAGAGFINFFMRSTARSLIISEILNKGKEFGRGNLGQSQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGY
DVTLEYYVNDAGRQMNILAVSVWLRYLELAGEPIVFPANGYKGQYVYEIAQEIWSEQGNQFVHPWISVVENLPADEPEGG
DKETYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSIEKGIQALKDRGHTYERE
GALWFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILV
QFAILYRGGDRVQMSTRSGSFVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLR
QLKERGLKWDKDMGLKNLDLLEQQHEATLISLIARYPEVIQSAAASCEPHQLAYYLRELANGLHSYYNAIQLLCEQEQLR
CARLCLLESVRQVLNNGLAILGVSAPESM

Sequences:

>Translated_589_residues
MRSMKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPKVLAERLVAVIPVDPSVE
KIEIAGAGFINFFMRSTARSLIISEILNKGKEFGRGNLGQSQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGY
DVTLEYYVNDAGRQMNILAVSVWLRYLELAGEPIVFPANGYKGQYVYEIAQEIWSEQGNQFVHPWISVVENLPADEPEGG
DKETYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSIEKGIQALKDRGHTYERE
GALWFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILV
QFAILYRGGDRVQMSTRSGSFVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLR
QLKERGLKWDKDMGLKNLDLLEQQHEATLISLIARYPEVIQSAAASCEPHQLAYYLRELANGLHSYYNAIQLLCEQEQLR
CARLCLLESVRQVLNNGLAILGVSAPESM
>Mature_589_residues
MRSMKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQAPKVLAERLVAVIPVDPSVE
KIEIAGAGFINFFMRSTARSLIISEILNKGKEFGRGNLGQSQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGY
DVTLEYYVNDAGRQMNILAVSVWLRYLELAGEPIVFPANGYKGQYVYEIAQEIWSEQGNQFVHPWISVVENLPADEPEGG
DKETYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFEDGSIEKGIQALKDRGHTYERE
GALWFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYDRGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILV
QFAILYRGGDRVQMSTRSGSFVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLR
QLKERGLKWDKDMGLKNLDLLEQQHEATLISLIARYPEVIQSAAASCEPHQLAYYLRELANGLHSYYNAIQLLCEQEQLR
CARLCLLESVRQVLNNGLAILGVSAPESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=600, Percent_Identity=23.3333333333333, Blast_Score=109, Evalue=6e-24,
Organism=Escherichia coli, GI1788184, Length=622, Percent_Identity=23.1511254019293, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985061, Length=606, Percent_Identity=22.6072607260726, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985068, Length=570, Percent_Identity=22.4561403508772, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320548, Length=563, Percent_Identity=26.6429840142096, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321883, Length=583, Percent_Identity=24.3567753001715, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI18859963, Length=605, Percent_Identity=22.9752066115702, Blast_Score=98, Evalue=2e-20,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 66031; Mature: 66031

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSMKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQ
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
APKVLAERLVAVIPVDPSVEKIEIAGAGFINFFMRSTARSLIISEILNKGKEFGRGNLGQ
HHHHHHHHHEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGYDVTLEYYVNDAGRQMNILAV
CHHHHHHEECCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHHHH
SVWLRYLELAGEPIVFPANGYKGQYVYEIAQEIWSEQGNQFVHPWISVVENLPADEPEGG
HHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCCCCC
DKETYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFED
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCC
GSIEKGIQALKDRGHTYEREGALWFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYD
CCHHHHHHHHHHCCCCEECCCEEEEEECCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHC
RGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILVQFAILYRGGDRVQMSTRSGS
CHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
FVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLR
EEEHHHHHHHHCCCCEEEEEEECCCHHHCCCCCEECCCCCCCCCEEEEEEHHHHHHHHHH
QLKERGLKWDKDMGLKNLDLLEQQHEATLISLIARYPEVIQSAAASCEPHQLAYYLRELA
HHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NGLHSYYNAIQLLCEQEQLRCARLCLLESVRQVLNNGLAILGVSAPESM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
>Mature Secondary Structure
MRSMKAIIEYLLKQALINLQQSGEMPIDLEIEIKVENAKDPAHGDYATNLALVLAKPCRQ
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
APKVLAERLVAVIPVDPSVEKIEIAGAGFINFFMRSTARSLIISEILNKGKEFGRGNLGQ
HHHHHHHHHEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SQKVLIEFVSANPTGPLHVGHGRGAAFGATLGNVLKAAGYDVTLEYYVNDAGRQMNILAV
CHHHHHHEECCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHHHH
SVWLRYLELAGEPIVFPANGYKGQYVYEIAQEIWSEQGNQFVHPWISVVENLPADEPEGG
HHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCCCCC
DKETYIDAIIARAQSLLGKDGFANFHQHALKTVLDDIKDDLQAFGVRFDSWFSEQSLFED
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCC
GSIEKGIQALKDRGHTYEREGALWFRATDFGDEKDRVLVRANGQTTYFASDVAYHWNKYD
CCHHHHHHHHHHCCCCEECCCEEEEEECCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHC
RGFDRVIDIFGADHHGYVTRIKTAVKALGHDESALDVILVQFAILYRGGDRVQMSTRSGS
CHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
FVTLRELREEVGNDAARYFYVARKPEQHMDFDLDLAKSESSDNPVYYIQYAHARICSVLR
EEEHHHHHHHHCCCCEEEEEEECCCHHHCCCCCEECCCCCCCCCEEEEEEHHHHHHHHHH
QLKERGLKWDKDMGLKNLDLLEQQHEATLISLIARYPEVIQSAAASCEPHQLAYYLRELA
HHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NGLHSYYNAIQLLCEQEQLRCARLCLLESVRQVLNNGLAILGVSAPESM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA