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The map label for this gene is cpdP [H]

Identifier: 52842162

GI number: 52842162

Start: 2172886

End: 2173869

Strand: Reverse

Name: cpdP [H]

Synonym: lpg1945

Alternate gene names: 52842162

Gene position: 2173869-2172886 (Counterclockwise)

Preceding gene: 52842163

Following gene: 52842160

Centisome position: 63.98

GC content: 38.72

Gene sequence:

>984_bases
ATGCGCCGTTTATTGATTACCATTCTTATTTTTTTATTATCTAATGCAGGATGTTGTGCGCCTGTCTTTGAAATTATTCC
TCTTGGAGTCTATGGTGGTTTGAAAGATGGAAATTTATCAGCTTATTTAATAAAAGCCATCGAGAGCAAAAATTATACGG
CTCTTGATGGGGGCACTTTGGTGCGTGGGCTTGAAGTCGCAGTCGATAGACAATCCCTGCCTAGTAAAAAGGTTGATGAT
TTGCTGCAAAAACATATTCCAGCTTACCTTATTTCTCATGCCCATCTTGATCATGTTATGGGGCTTGTGATGGCGCAACC
CGAATTGCGAGAAAAGCAAACCATTATGGCGCGTGAAGAAACAATGCAGGCATTGCAGGACAATATTTTTAATTGGTCTG
TCTGGGGGAATTTTGGAGATAGCGGAGCAATTCCTCATTTGAATTTTCAGCATTATCAAACTCTGCCATTACTCCAGTGG
CTTGCTATTCCTGATACAGATTTGCACGTTAAAGTGTTTCCTTTGAGCCATAGCGGAATGGCATCAAGCGCTTTTTTAAT
ACGTTATAAAACCGAATATGCCCTCTATTTTGGTGATACTGGTGCTGATCGCATTGAAAAGTCGACAAATATGGAGAATA
TTTGGAAAGAAATTGCCCCACTGATAAGAAATAAGCAGCTTCATGCCATCATGCTGGAGTGCTCATTTTTAAATTCACAA
CCAGATGACAAATTATTTGGCCATTTAAAACCAAACTTGTTTATGTCAGAGTTGCGGCACTTGGCATCGATTGTTGATCC
TTTCGACTCAAGAAACTCATTACGAGGTTTACCCGTTGTTGTTACACACATCAAACCCAAATTAGCTGACTTTTCAAATA
CTAATGAAGATACAGAAAAACAGGTCATAAACGAATTATCCCAGGAAAATGATATTGGTGTCGAATTAATTAAACCTGAA
CAAGGTATAACCTTAAGTTTATGA

Upstream 100 bases:

>100_bases
TATGATGCTGAACTTCTACCGTATAAATACGGTAATTTAAGCAAGGCTGAATACTGTATTATTTTACAAACTTACTTGAA
TCATTTGAAAGGAAATCCTC

Downstream 100 bases:

>100_bases
TTGATGAAGAGTCACAACAGCCGCCAGAACCAACCCTAATAAATCATTTATGGTATTTGTGTATCAGGGGCTGTTGCGAA
AAGTCCGAACCAGAATAAAA

Product: 3',5'-cyclic nucleotide phosphodiesterase

Products: NA

Alternate protein names: 3':5'-CNP; PDEase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MRRLLITILIFLLSNAGCCAPVFEIIPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTLVRGLEVAVDRQSLPSKKVDD
LLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREETMQALQDNIFNWSVWGNFGDSGAIPHLNFQHYQTLPLLQW
LAIPDTDLHVKVFPLSHSGMASSAFLIRYKTEYALYFGDTGADRIEKSTNMENIWKEIAPLIRNKQLHAIMLECSFLNSQ
PDDKLFGHLKPNLFMSELRHLASIVDPFDSRNSLRGLPVVVTHIKPKLADFSNTNEDTEKQVINELSQENDIGVELIKPE
QGITLSL

Sequences:

>Translated_327_residues
MRRLLITILIFLLSNAGCCAPVFEIIPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTLVRGLEVAVDRQSLPSKKVDD
LLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREETMQALQDNIFNWSVWGNFGDSGAIPHLNFQHYQTLPLLQW
LAIPDTDLHVKVFPLSHSGMASSAFLIRYKTEYALYFGDTGADRIEKSTNMENIWKEIAPLIRNKQLHAIMLECSFLNSQ
PDDKLFGHLKPNLFMSELRHLASIVDPFDSRNSLRGLPVVVTHIKPKLADFSNTNEDTEKQVINELSQENDIGVELIKPE
QGITLSL
>Mature_327_residues
MRRLLITILIFLLSNAGCCAPVFEIIPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTLVRGLEVAVDRQSLPSKKVDD
LLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREETMQALQDNIFNWSVWGNFGDSGAIPHLNFQHYQTLPLLQW
LAIPDTDLHVKVFPLSHSGMASSAFLIRYKTEYALYFGDTGADRIEKSTNMENIWKEIAPLIRNKQLHAIMLECSFLNSQ
PDDKLFGHLKPNLFMSELRHLASIVDPFDSRNSLRGLPVVVTHIKPKLADFSNTNEDTEKQVINELSQENDIGVELIKPE
QGITLSL

Specific function: Seems to allow the organism to grow on cAMP [H]

COG id: COG5212

COG function: function code T; Low-affinity cAMP phosphodiesterase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cAMP phosphodiesterase class-II family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321189, Length=222, Percent_Identity=29.2792792792793, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR000396 [H]

Pfam domain/function: PF02112 PDEase_II [H]

EC number: =3.1.4.17 [H]

Molecular weight: Translated: 36741; Mature: 36741

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLITILIFLLSNAGCCAPVFEIIPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTL
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEECCCHH
VRGLEVAVDRQSLPSKKVDDLLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREE
HHHHHHEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TMQALQDNIFNWSVWGNFGDSGAIPHLNFQHYQTLPLLQWLAIPDTDLHVKVFPLSHSGM
HHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
ASSAFLIRYKTEYALYFGDTGADRIEKSTNMENIWKEIAPLIRNKQLHAIMLECSFLNSQ
CCCEEEEEEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEHHCCCC
PDDKLFGHLKPNLFMSELRHLASIVDPFDSRNSLRGLPVVVTHIKPKLADFSNTNEDTEK
CCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCHHHH
QVINELSQENDIGVELIKPEQGITLSL
HHHHHHHCCCCCCEEEECCCCCCEECC
>Mature Secondary Structure
MRRLLITILIFLLSNAGCCAPVFEIIPLGVYGGLKDGNLSAYLIKAIESKNYTALDGGTL
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEECCCHH
VRGLEVAVDRQSLPSKKVDDLLQKHIPAYLISHAHLDHVMGLVMAQPELREKQTIMAREE
HHHHHHEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TMQALQDNIFNWSVWGNFGDSGAIPHLNFQHYQTLPLLQWLAIPDTDLHVKVFPLSHSGM
HHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
ASSAFLIRYKTEYALYFGDTGADRIEKSTNMENIWKEIAPLIRNKQLHAIMLECSFLNSQ
CCCEEEEEEEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEHHCCCC
PDDKLFGHLKPNLFMSELRHLASIVDPFDSRNSLRGLPVVVTHIKPKLADFSNTNEDTEK
CCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCHHHH
QVINELSQENDIGVELIKPEQGITLSL
HHHHHHHCCCCCCEEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8393003 [H]