Click here to switch to the map view.

The map label for this gene is hipA [C]

Identifier: 52842151

GI number: 52842151

Start: 2158922

End: 2160232

Strand: Reverse

Name: hipA [C]

Synonym: lpg1934

Alternate gene names: 52842151

Gene position: 2160232-2158922 (Counterclockwise)

Preceding gene: 52842152

Following gene: 52842150

Centisome position: 63.58

GC content: 34.78

Gene sequence:

>1311_bases
ATGGTGAGGATGAAAATGATTGGAGATAAGTCAGTCTTGGATGTTTATCTCGGTGAAAGTCAAATAGCCAACATCACACT
TATCGATGATCAACTGTATTGGAGTTATCATGAAAGTTGGCAACAGACAGGGTATGCTATTTCCCCGCACCTTCCTATGC
ATGAAGATATTCCACCATTAAATGTGCAACGATTTCTAAGAAATTTATTACCCGAAGGAAATCCTTTAGAAGTACTAGTT
AATGTTTTTCATTTAAGTAAATACAATACATTTGGACTTATTCAAGCTTTAGGGTTGGATACACCTGGGTCATTAGTTAT
ATTGCCATCAAATCAAGCAATTCCTAAACATGCTAATTTTCGACTAGTAACTCATGAAGAATTAGAAGATCGTTTAAATC
ATTGTGATTCTTACAATTTAATCGTTTGGGACGGAAAACCACGTCTTTCAGTTGCCGGAGTACAAGATAAAATTAATGTG
GTGTTAAATAAAGAAGGACAACTTGGTTTTGGAGAAGGTAGCTTGTGTTCTACCCATATTCTTAAATTTGAAACACAAAA
ACTATCTTATCTGGTTTTAAATGAATTCCTCAGTATGTGGCTCGCTAAATGCTGTGAATTGAATGTAGCCAATGTTCAGA
TGAAGCGTTTTGGTCAGAACCCTGCTTTATTAGTAGAGCGTTTTGATAGGAAATTGATTACCACTAATATAGTAAAAAGA
CGGCACTTAATAGATGGTTGTCAGGCAATGAATTTACCCCCTGAATTTAAATATGAGCAAAATTTTGGAAATAACAGGGA
TGTGGCTCATATTAGAGATGGAGTCAGTTTGCCCAAGCTATTTGATTTTGCCAATCAATGTATCAATCCTGCCAAAACCA
AGCAACAAATACTCGACTGGGTTTTATTTAATGTTTTGATATTTAATTGTGACGCTCACGGTAAAAATATCAGTTTTTTT
GTTGGAGTTAACGGTATATCACTGGCGCCATTTTATGATTTGGTTAATATAAAAATGTATCCTGAATTTGAGCATGCTCT
GGCGATGGCATTAGGGGATGAATTTGATGGTGATAATATTAATGCTTATCAGTTGGCTGATTTTGCAGATACATGTAGGC
TGCCAAGGTCGTTAGTAGCTAAACATTTAAAATATTTGATTGGCAAATTAACAACTGCTTTGCAAGAAGAAACCCAATTT
AATTTAGTTGGTAACGAAGAAGACTATTTTAAGAAATATCAGGAAATTGTCATGAAGAGATGTGAACACTTGTTAAAGCA
GAACGACCAAATTACTTCAATAAAGCTCTAG

Upstream 100 bases:

>100_bases
ATGAAAATCGAGCATGGGCAATCGAACTGTCAATTGGCAAGTGTATTACAAATTTGTTCTGGTTTAGGAATAAATCTTTA
CATAAAACCTTGGATGGATA

Downstream 100 bases:

>100_bases
CGCCTTTCCTCATTATTTCTTACTTTAATACGGAGCACATAAGAGATTTGTATATTTAATATACAAACAATCTATTTTAA
TTATAATCAAATATATCATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MVRMKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPLNVQRFLRNLLPEGNPLEVLV
NVFHLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANFRLVTHEELEDRLNHCDSYNLIVWDGKPRLSVAGVQDKINV
VLNKEGQLGFGEGSLCSTHILKFETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTNIVKR
RHLIDGCQAMNLPPEFKYEQNFGNNRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDWVLFNVLIFNCDAHGKNISFF
VGVNGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGDNINAYQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQF
NLVGNEEDYFKKYQEIVMKRCEHLLKQNDQITSIKL

Sequences:

>Translated_436_residues
MVRMKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPLNVQRFLRNLLPEGNPLEVLV
NVFHLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANFRLVTHEELEDRLNHCDSYNLIVWDGKPRLSVAGVQDKINV
VLNKEGQLGFGEGSLCSTHILKFETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTNIVKR
RHLIDGCQAMNLPPEFKYEQNFGNNRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDWVLFNVLIFNCDAHGKNISFF
VGVNGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGDNINAYQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQF
NLVGNEEDYFKKYQEIVMKRCEHLLKQNDQITSIKL
>Mature_436_residues
MVRMKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPLNVQRFLRNLLPEGNPLEVLV
NVFHLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANFRLVTHEELEDRLNHCDSYNLIVWDGKPRLSVAGVQDKINV
VLNKEGQLGFGEGSLCSTHILKFETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTNIVKR
RHLIDGCQAMNLPPEFKYEQNFGNNRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDWVLFNVLIFNCDAHGKNISFF
VGVNGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGDNINAYQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQF
NLVGNEEDYFKKYQEIVMKRCEHLLKQNDQITSIKL

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=324, Percent_Identity=28.3950617283951, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 49860; Mature: 49860

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRMKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPL
CEEEEECCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCEEECCCCCCCCCCCCC
NVQRFLRNLLPEGNPLEVLVNVFHLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANF
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCE
RLVTHEELEDRLNHCDSYNLIVWDGKPRLSVAGVQDKINVVLNKEGQLGFGEGSLCSTHI
EEEEHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCEEEEEEECCCCCCCCCCCHHHHHH
LKFETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTNIVKR
EEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RHLIDGCQAMNLPPEFKYEQNFGNNRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDW
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHH
VLFNVLIFNCDAHGKNISFFVGVNGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGDNI
HHHHHHHEECCCCCCCEEEEEECCCCEECCHHEEEEEEECCCHHHHHHHHHCCCCCCCCC
NAYQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQFNLVGNEEDYFKKYQEIVMKR
CCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
CEHLLKQNDQITSIKL
HHHHHHCCCCEEEEEC
>Mature Secondary Structure
MVRMKMIGDKSVLDVYLGESQIANITLIDDQLYWSYHESWQQTGYAISPHLPMHEDIPPL
CEEEEECCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCEEECCCCCCCCCCCCC
NVQRFLRNLLPEGNPLEVLVNVFHLSKYNTFGLIQALGLDTPGSLVILPSNQAIPKHANF
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCE
RLVTHEELEDRLNHCDSYNLIVWDGKPRLSVAGVQDKINVVLNKEGQLGFGEGSLCSTHI
EEEEHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCEEEEEEECCCCCCCCCCCHHHHHH
LKFETQKLSYLVLNEFLSMWLAKCCELNVANVQMKRFGQNPALLVERFDRKLITTNIVKR
EEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RHLIDGCQAMNLPPEFKYEQNFGNNRDVAHIRDGVSLPKLFDFANQCINPAKTKQQILDW
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHH
VLFNVLIFNCDAHGKNISFFVGVNGISLAPFYDLVNIKMYPEFEHALAMALGDEFDGDNI
HHHHHHHEECCCCCCCEEEEEECCCCEECCHHEEEEEEECCCHHHHHHHHHCCCCCCCCC
NAYQLADFADTCRLPRSLVAKHLKYLIGKLTTALQEETQFNLVGNEEDYFKKYQEIVMKR
CCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
CEHLLKQNDQITSIKL
HHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]