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The map label for this gene is bolA

Identifier: 52842134

GI number: 52842134

Start: 2138991

End: 2139308

Strand: Direct

Name: bolA

Synonym: lpg1916

Alternate gene names: 52842134

Gene position: 2138991-2139308 (Clockwise)

Preceding gene: 52842131

Following gene: 52842135

Centisome position: 62.95

GC content: 37.74

Gene sequence:

>318_bases
ATGACGCGTAAACTCCGCATAGAAGAAAAACTAATCTCCGCATTATCCCCCCTCTTTTTAAGTGTTGAAGACGAGTCCAT
GAACCATCACGTTCCTCAAGGCGCTGAAACACATTTTAAAATAATCGCCGTTTCAAATCATTTTAATGATCTGACTCGTA
TTAATCGTCATAAATTCGTTAATCAGCTTCTTAAAGAAGAATTTACTCTGGGGCTGCATGCATTAAGCATGCATTTATAT
ACTTCTGATGAATGGATGACTCAACAGCAATCGGTACTCAAATCACCTGCTTGCAGAGATGGCTATAAAAACAAATAA

Upstream 100 bases:

>100_bases
ACAATTTTTGTCACATTCTGACAATTGTGTTTAATTAATGTGACAACTATGCTTCAAATGTATATACTCCTTATTTTGCA
AAAACAGAGTCGAGCAAATC

Downstream 100 bases:

>100_bases
TTTTAATGAAAAAAGTTCACCTCCAAGCTTGATTTATTTTATAATGTCTATCTTTTTATCAAATAGAAAAATCAATGAAA
TCATGGTCCTCTGAAAAAAT

Product: regulator of murein genes BolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MTRKLRIEEKLISALSPLFLSVEDESMNHHVPQGAETHFKIIAVSNHFNDLTRINRHKFVNQLLKEEFTLGLHALSMHLY
TSDEWMTQQQSVLKSPACRDGYKNK

Sequences:

>Translated_105_residues
MTRKLRIEEKLISALSPLFLSVEDESMNHHVPQGAETHFKIIAVSNHFNDLTRINRHKFVNQLLKEEFTLGLHALSMHLY
TSDEWMTQQQSVLKSPACRDGYKNK
>Mature_104_residues
TRKLRIEEKLISALSPLFLSVEDESMNHHVPQGAETHFKIIAVSNHFNDLTRINRHKFVNQLLKEEFTLGLHALSMHLYT
SDEWMTQQQSVLKSPACRDGYKNK

Specific function: Plays an important role in general stress response (heat shock, acidic stress, oxidative stress, carbon-starvation stress and osmotic shock). Involved in morphogenetic pathway. Has a role in the induction of the expression of dacA (PBP5), dacC (PBP6) and

COG id: COG0271

COG function: function code T; Stress-induced morphogen (activity unknown)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bolA/yrbA family [H]

Homologues:

Organism=Homo sapiens, GI7705638, Length=97, Percent_Identity=40.2061855670103, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081740, Length=101, Percent_Identity=45.5445544554455, Blast_Score=100, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17541430, Length=96, Percent_Identity=40.625, Blast_Score=78, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221459039, Length=96, Percent_Identity=41.6666666666667, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002634 [H]

Pfam domain/function: PF01722 BolA [H]

EC number: NA

Molecular weight: Translated: 12220; Mature: 12089

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKLRIEEKLISALSPLFLSVEDESMNHHVPQGAETHFKIIAVSNHFNDLTRINRHKFV
CCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
NQLLKEEFTLGLHALSMHLYTSDEWMTQQQSVLKSPACRDGYKNK
HHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TRKLRIEEKLISALSPLFLSVEDESMNHHVPQGAETHFKIIAVSNHFNDLTRINRHKFV
CCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
NQLLKEEFTLGLHALSMHLYTSDEWMTQQQSVLKSPACRDGYKNK
HHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]