Click here to switch to the map view.

The map label for this gene is yheS [H]

Identifier: 52842089

GI number: 52842089

Start: 2088377

End: 2090254

Strand: Direct

Name: yheS [H]

Synonym: lpg1868

Alternate gene names: 52842089

Gene position: 2088377-2090254 (Clockwise)

Preceding gene: 52842088

Following gene: 52842094

Centisome position: 61.46

GC content: 38.66

Gene sequence:

>1878_bases
CTGATTAGTTCAAGCTTACGGTATAACATGCTTACATTGCGTCAAATTACTTTATCCAGAGGAGATAAAATTTTACTCGA
TAAGGTCAATGTCAGTCTTTATGAAAAACAAAAAATTGGCCTTATCGGTCATAATGGATGTGGAAAATCAACATTATTTG
ATTTTCTTTTAGGTCAATTATCTCCTGATACTGGAGAATATCTAATTAATCCACAACTCAGCATCAGTCATTTGTCTCAA
CACATACCTGATAGCAATGAAAAAGCTTTGGATTTTGTTCTTGCCGGAGATCAACAATACATTAAATTGCTAAAGCGCCT
TTCAGAAGCTGAAAAAAACGGCGATGATGCAGAGGTTTTGCAATGTCACGAGGAACTCTCTCATACTGGTGGTTACAGTA
AGCCCGCGCAAGCAGCAGTTATTATGTCTGGCTTAGGATTTAGTGGAAATCAACAGCAAGAGCCCGTTAACAGCTTTTCT
GGTGGCTGGAGAATGCGCTTAAATCTTGCTCGGTGCTTAATGAAACCCGCCGATTTACTCCTGCTTGATGAACCCACAAA
CCATTTAGACATGGAAGCCATCTTCTGGCTGGAACGCTATTTAAAACAAAGTCCAAGTACTATTATTCTTATTTCACATG
ATAGAGAATTTCTTGATGCCTTTGTTACTCATATATTACATATAGAAAATCGTAATCTGACACTTTATTCAGGAAACTAT
AGCAGCTTTGAAAAAACTCATGCGCAACAACTGGCTCTGCAACAAGCAATGCATGAAAAGCAACAAACCAAAATCAAACA
TATGATGACTTTTGTAACTCGTTTTAAAGCGAAAGCAGCCAAGGCCAAACAAGCGCAAAGTCGAATGAAAGCTATAGAAA
AGATGGAAATAATTGCAGCAGCCCAAGCCGACTCCCCTTTTTCTTTTGATTTTTTCCCTTGTCCTCGGGCAGGAAATCCT
TTAATTCAATGCAATCAAGTTGATGCAGGATATATCAATCATCCTCCGATTTTGAAAAAAATCAAACTCTCTCTTAATCC
CGGCGATAGAATTGCGCTACTGGGACCTAACGGTGAAGGAAAATCAACCTTAATTAAAACGCTTACAGCAGATTTGCCCG
TATTAAGTGGAGATATTCATCGTTCTCCACACTTACAAATAGGCTACTACGCTCAGCATCAACTTGAGCAATTAAACTGT
AAATTAAGTCCGGTAGAAACACTGCAAACTCTCTCGCCAGAGGTAAGAGAACAAACCATACGGGATTTTTTAGGTGGGTT
TAATTTCAGAGGGGACATGGCGGTACAATCCATTCAGCACTTTTCAGGTGGTGAAAAAGCCCGCCTGGCATTAGCAAGAC
TGGTTTGGCTAAAACCCAATCTTCTTTTGCTGGATGAGCCAACAAACCATTTGGATCTTGGAATGCGCTCAGCAATTGAA
TTAGCGCTGCAAACTTATGAGGGTGCCTTAATTTTGATTTCGCATGACCGCCATTTGTTAAAATCAAGTGTGGACAACTT
TTATCTTATTTATCAAGGAAAAGTACAACCATTTGAAGGGGATCTTGATGATTACTATCTCTGGCTGCAAACCAGAAATT
CAGAAAAGGAATCCAAATTAGCTACTTCCCCAAATGAATATAAAGAAAGAAAAAGCTATCAAAACAAATTAAAAAAGCTG
GAGCAACTCATTGAGCACTATCAGAATCAATTGCGCCTTCTTGATAAGCAGTTAGCTGACGTTTCTCTGTATGAAGACAC
AAAGCAGAAAAGCAAATTGGATAATCTTTTGATGGAACGAGATATCGCTCATTCTTCTTTAATGAAGACAGAAGAAGAGT
GGTTAGAAATATGTAATGCTCTGGAAAACCTGGAGTAA

Upstream 100 bases:

>100_bases
AATAATTTATTTTTAAAGAAAATCTGGTTTTAAACTTATGCAAATATCCAGCTCGCTTACATGATCAATAGGAAGCTTAA
GCTAATTTATGATAAAATGA

Downstream 100 bases:

>100_bases
GTAATAGGTTCTGCTAATCAATACCATTTAACCTTGTAACTGTTCCAACATGGCTTTTGCTGCCAACTGCTCAGCTTTTC
TTCTATTAGGCCCTGTGCCA

Product: ABC transporter, ATP-binding component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MISSSLRYNMLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQLSPDTGEYLINPQLSISHLSQ
HIPDSNEKALDFVLAGDQQYIKLLKRLSEAEKNGDDAEVLQCHEELSHTGGYSKPAQAAVIMSGLGFSGNQQQEPVNSFS
GGWRMRLNLARCLMKPADLLLLDEPTNHLDMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNY
SSFEKTHAQQLALQQAMHEKQQTKIKHMMTFVTRFKAKAAKAKQAQSRMKAIEKMEIIAAAQADSPFSFDFFPCPRAGNP
LIQCNQVDAGYINHPPILKKIKLSLNPGDRIALLGPNGEGKSTLIKTLTADLPVLSGDIHRSPHLQIGYYAQHQLEQLNC
KLSPVETLQTLSPEVREQTIRDFLGGFNFRGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIE
LALQTYEGALILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKLATSPNEYKERKSYQNKLKKL
EQLIEHYQNQLRLLDKQLADVSLYEDTKQKSKLDNLLMERDIAHSSLMKTEEEWLEICNALENLE

Sequences:

>Translated_625_residues
MISSSLRYNMLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQLSPDTGEYLINPQLSISHLSQ
HIPDSNEKALDFVLAGDQQYIKLLKRLSEAEKNGDDAEVLQCHEELSHTGGYSKPAQAAVIMSGLGFSGNQQQEPVNSFS
GGWRMRLNLARCLMKPADLLLLDEPTNHLDMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNY
SSFEKTHAQQLALQQAMHEKQQTKIKHMMTFVTRFKAKAAKAKQAQSRMKAIEKMEIIAAAQADSPFSFDFFPCPRAGNP
LIQCNQVDAGYINHPPILKKIKLSLNPGDRIALLGPNGEGKSTLIKTLTADLPVLSGDIHRSPHLQIGYYAQHQLEQLNC
KLSPVETLQTLSPEVREQTIRDFLGGFNFRGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIE
LALQTYEGALILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKLATSPNEYKERKSYQNKLKKL
EQLIEHYQNQLRLLDKQLADVSLYEDTKQKSKLDNLLMERDIAHSSLMKTEEEWLEICNALENLE
>Mature_625_residues
MISSSLRYNMLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQLSPDTGEYLINPQLSISHLSQ
HIPDSNEKALDFVLAGDQQYIKLLKRLSEAEKNGDDAEVLQCHEELSHTGGYSKPAQAAVIMSGLGFSGNQQQEPVNSFS
GGWRMRLNLARCLMKPADLLLLDEPTNHLDMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNY
SSFEKTHAQQLALQQAMHEKQQTKIKHMMTFVTRFKAKAAKAKQAQSRMKAIEKMEIIAAAQADSPFSFDFFPCPRAGNP
LIQCNQVDAGYINHPPILKKIKLSLNPGDRIALLGPNGEGKSTLIKTLTADLPVLSGDIHRSPHLQIGYYAQHQLEQLNC
KLSPVETLQTLSPEVREQTIRDFLGGFNFRGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIE
LALQTYEGALILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKLATSPNEYKERKSYQNKLKKL
EQLIEHYQNQLRLLDKQLADVSLYEDTKQKSKLDNLLMERDIAHSSLMKTEEEWLEICNALENLE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=534, Percent_Identity=36.5168539325843, Blast_Score=349, Evalue=5e-96,
Organism=Homo sapiens, GI10947137, Length=524, Percent_Identity=34.7328244274809, Blast_Score=308, Evalue=1e-83,
Organism=Homo sapiens, GI27881506, Length=524, Percent_Identity=34.7328244274809, Blast_Score=308, Evalue=1e-83,
Organism=Homo sapiens, GI10947135, Length=548, Percent_Identity=32.6642335766423, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI69354671, Length=548, Percent_Identity=32.6642335766423, Blast_Score=251, Evalue=2e-66,
Organism=Escherichia coli, GI1789751, Length=634, Percent_Identity=45.7413249211356, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=34.593572778828, Blast_Score=299, Evalue=4e-82,
Organism=Escherichia coli, GI1787182, Length=645, Percent_Identity=29.7674418604651, Blast_Score=241, Evalue=9e-65,
Organism=Escherichia coli, GI2367384, Length=530, Percent_Identity=30.188679245283, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI48995001, Length=524, Percent_Identity=23.8549618320611, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788165, Length=173, Percent_Identity=32.9479768786127, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788506, Length=247, Percent_Identity=26.7206477732794, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789864, Length=247, Percent_Identity=25.1012145748988, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787758, Length=194, Percent_Identity=27.319587628866, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787500, Length=212, Percent_Identity=25, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI87081709, Length=182, Percent_Identity=26.9230769230769, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787547, Length=200, Percent_Identity=28, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=528, Percent_Identity=36.3636363636364, Blast_Score=335, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17555318, Length=514, Percent_Identity=35.9922178988327, Blast_Score=301, Evalue=6e-82,
Organism=Caenorhabditis elegans, GI17559834, Length=542, Percent_Identity=31.3653136531365, Blast_Score=285, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17542146, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=528, Percent_Identity=35.2272727272727, Blast_Score=327, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6320874, Length=525, Percent_Identity=32.3809523809524, Blast_Score=285, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6325030, Length=388, Percent_Identity=33.2474226804124, Blast_Score=174, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6324314, Length=400, Percent_Identity=29.75, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323278, Length=403, Percent_Identity=29.5285359801489, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=37.1916508538899, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI24642252, Length=525, Percent_Identity=36.952380952381, Blast_Score=335, Evalue=5e-92,
Organism=Drosophila melanogaster, GI18859989, Length=525, Percent_Identity=36.952380952381, Blast_Score=335, Evalue=5e-92,
Organism=Drosophila melanogaster, GI24641342, Length=536, Percent_Identity=32.089552238806, Blast_Score=288, Evalue=6e-78,
Organism=Drosophila melanogaster, GI24638550, Length=196, Percent_Identity=25.5102040816327, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24638552, Length=196, Percent_Identity=25.5102040816327, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24638554, Length=196, Percent_Identity=25.5102040816327, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24638546, Length=196, Percent_Identity=25.5102040816327, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24638556, Length=196, Percent_Identity=25.5102040816327, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24638548, Length=196, Percent_Identity=25.5102040816327, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24638558, Length=196, Percent_Identity=25.5102040816327, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70982; Mature: 70982

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSSLRYNMLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQL
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCEEECCCCCHHHHHHHHHHHC
SPDTGEYLINPQLSISHLSQHIPDSNEKALDFVLAGDQQYIKLLKRLSEAEKNGDDAEVL
CCCCCCEEECCCCCHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHH
QCHEELSHTGGYSKPAQAAVIMSGLGFSGNQQQEPVNSFSGGWRMRLNLARCLMKPADLL
HHHHHHHHCCCCCCCHHHHHHEECCCCCCCCCCCCHHHCCCCEEEEHHHHHHHCCCCCEE
LLDEPTNHLDMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNY
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHEEECCEEEEEECCC
SSFEKTHAQQLALQQAMHEKQQTKIKHMMTFVTRFKAKAAKAKQAQSRMKAIEKMEIIAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
AQADSPFSFDFFPCPRAGNPLIQCNQVDAGYINHPPILKKIKLSLNPGDRIALLGPNGEG
ECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCC
KSTLIKTLTADLPVLSGDIHRSPHLQIGYYAQHQLEQLNCKLSPVETLQTLSPEVREQTI
HHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHH
RDFLGGFNFRGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIE
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH
LALQTYEGALILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKL
HHHHHCCCEEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHC
ATSPNEYKERKSYQNKLKKLEQLIEHYQNQLRLLDKQLADVSLYEDTKQKSKLDNLLMER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIAHSSLMKTEEEWLEICNALENLE
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISSSLRYNMLTLRQITLSRGDKILLDKVNVSLYEKQKIGLIGHNGCGKSTLFDFLLGQL
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCEEECCCCCHHHHHHHHHHHC
SPDTGEYLINPQLSISHLSQHIPDSNEKALDFVLAGDQQYIKLLKRLSEAEKNGDDAEVL
CCCCCCEEECCCCCHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCHHHHH
QCHEELSHTGGYSKPAQAAVIMSGLGFSGNQQQEPVNSFSGGWRMRLNLARCLMKPADLL
HHHHHHHHCCCCCCCHHHHHHEECCCCCCCCCCCCHHHCCCCEEEEHHHHHHHCCCCCEE
LLDEPTNHLDMEAIFWLERYLKQSPSTIILISHDREFLDAFVTHILHIENRNLTLYSGNY
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHEEECCEEEEEECCC
SSFEKTHAQQLALQQAMHEKQQTKIKHMMTFVTRFKAKAAKAKQAQSRMKAIEKMEIIAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
AQADSPFSFDFFPCPRAGNPLIQCNQVDAGYINHPPILKKIKLSLNPGDRIALLGPNGEG
ECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCC
KSTLIKTLTADLPVLSGDIHRSPHLQIGYYAQHQLEQLNCKLSPVETLQTLSPEVREQTI
HHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHH
RDFLGGFNFRGDMAVQSIQHFSGGEKARLALARLVWLKPNLLLLDEPTNHLDLGMRSAIE
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH
LALQTYEGALILISHDRHLLKSSVDNFYLIYQGKVQPFEGDLDDYYLWLQTRNSEKESKL
HHHHHCCCEEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHC
ATSPNEYKERKSYQNKLKKLEQLIEHYQNQLRLLDKQLADVSLYEDTKQKSKLDNLLMER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIAHSSLMKTEEEWLEICNALENLE
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]