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The map label for this gene is tig

Identifier: 52842087

GI number: 52842087

Start: 2084862

End: 2086193

Strand: Reverse

Name: tig

Synonym: lpg1862

Alternate gene names: 52842087

Gene position: 2086193-2084862 (Counterclockwise)

Preceding gene: 52842090

Following gene: 52842086

Centisome position: 61.4

GC content: 38.96

Gene sequence:

>1332_bases
ATGCAAGTTTCTGTTGAGACCCTAGAAGGTTTGGAGCGTAAGGTTACAGTTTCTGTACCTACAGAGAAAGTTGAGGAAGA
GGTGAGCTCGCGTCTCAGAAATCTTGCTCGCAAAGTGAAAATAGATGGTTTTCGTCCAGGCAAAGTCCCTTTTAATGTTG
TAAAAAGCCGTTTCTCTGATAGTGTGCGTGAAGAAGTTGCCCGGGAAATGGTCCAATCTACCTTATATGAAGCCTTACAA
AAAAATGAATTGGTTCCAGCAGGTTATCCTCATGTTGAGCCTTTAGAAATCGAACCAGGTAAGGATTTTAAATACACTGC
TGTATTTGAAGTTATGCCCGTTTTTGAAATTGTCGAGCTCAATCAAGCTCCAGTGGAATTAATTCGATCTGAAGTCACTG
ATAAAGATGTTGACAACATGATTGAAAAATTACGAGAACAAAACAAAGAGTGGCATGAAGTAACTCATGCGGTCAAAAAA
GGTGATAAAGTTGTTATTGATTTTCAGGGATTTTTGGATGATAAGCCATTCCAGGGCGGCAGTGCTGAAGGATATGAGCT
TGTAATTGGTTCTGGTTCGATGATTCCCGGATTTGAAGATGGGATTGTTGGTGGGAAAATTGACAAACCGTTCGATATCA
AAGTGAGTTTCCCGGAAGATTATGGCCATAAAGATTTGGCTGGGAAGGAAGCAACGTTCAAGATCACTATCAAAAAGATT
ATGGAAGGCAAGTTGCCTGCTTTGGACGAGGCATTTGCAGAGAAATTTAATATAAAAGAAGGTGGTATAGAGTCTCTTAA
AAAGGATATTAGAGAAAATATGGCTCGTGAATTAGAACGTCGGGTCAACATGATGAACAGAGAGAAACTGTTTGATTCAT
TAATGTCTGTGAATCATGTTGAGTTGCCAATAGCTTTGATAGATAAAGAAATTGAGCATTTAAAGCATGATATGTATCAC
CGATTGTTTGGTCACGAACATAAAGACGATGAAAAAATTCCTGATTTCCCAAGGGAGTTATTTGAAGAGCAAGCCAAGCG
ACGCGTACACTTGGGCTTACTTTTTGCCGAGTATGTAAAAAAACACGAAATTGTTGCAGACAACGACAAAGTTAATGCTA
TGATTGATAAATTTGCCAGTGCTTACGAAAGTCCTGATGAGCTTCGCGCGTGGTATCAAAGCAGCAAAGAGCATATGGCT
GAAGTTGAAGCATTAGTTATGGAAGATATGGTTGCTGATAAAATAGCAGAAGATGCGAAACTTAAATACAAAAATATGGA
TTATGATTCAGTGATGAATCCCAAAAAGGGCACTGAGAAAAAAGGAGAGTAA

Upstream 100 bases:

>100_bases
ATTGGTAGACGCACTGGATTTAGGTTCCAGCGGGGCGACCCGTGAGAGTTCGAGTCTCTCCTTTCGCACCATTTCATGAT
AACTTCCGAGAGGTGAATTA

Downstream 100 bases:

>100_bases
GCATGCCAGGCTATTCAGATAATATTATCCGTAATGCAAGCGGATTAATACCAATGGTCATTGAGCAAACCTCGCGAGGT
GAGCGTTCCTATGACATTTA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MQVSVETLEGLERKVTVSVPTEKVEEEVSSRLRNLARKVKIDGFRPGKVPFNVVKSRFSDSVREEVAREMVQSTLYEALQ
KNELVPAGYPHVEPLEIEPGKDFKYTAVFEVMPVFEIVELNQAPVELIRSEVTDKDVDNMIEKLREQNKEWHEVTHAVKK
GDKVVIDFQGFLDDKPFQGGSAEGYELVIGSGSMIPGFEDGIVGGKIDKPFDIKVSFPEDYGHKDLAGKEATFKITIKKI
MEGKLPALDEAFAEKFNIKEGGIESLKKDIRENMARELERRVNMMNREKLFDSLMSVNHVELPIALIDKEIEHLKHDMYH
RLFGHEHKDDEKIPDFPRELFEEQAKRRVHLGLLFAEYVKKHEIVADNDKVNAMIDKFASAYESPDELRAWYQSSKEHMA
EVEALVMEDMVADKIAEDAKLKYKNMDYDSVMNPKKGTEKKGE

Sequences:

>Translated_443_residues
MQVSVETLEGLERKVTVSVPTEKVEEEVSSRLRNLARKVKIDGFRPGKVPFNVVKSRFSDSVREEVAREMVQSTLYEALQ
KNELVPAGYPHVEPLEIEPGKDFKYTAVFEVMPVFEIVELNQAPVELIRSEVTDKDVDNMIEKLREQNKEWHEVTHAVKK
GDKVVIDFQGFLDDKPFQGGSAEGYELVIGSGSMIPGFEDGIVGGKIDKPFDIKVSFPEDYGHKDLAGKEATFKITIKKI
MEGKLPALDEAFAEKFNIKEGGIESLKKDIRENMARELERRVNMMNREKLFDSLMSVNHVELPIALIDKEIEHLKHDMYH
RLFGHEHKDDEKIPDFPRELFEEQAKRRVHLGLLFAEYVKKHEIVADNDKVNAMIDKFASAYESPDELRAWYQSSKEHMA
EVEALVMEDMVADKIAEDAKLKYKNMDYDSVMNPKKGTEKKGE
>Mature_443_residues
MQVSVETLEGLERKVTVSVPTEKVEEEVSSRLRNLARKVKIDGFRPGKVPFNVVKSRFSDSVREEVAREMVQSTLYEALQ
KNELVPAGYPHVEPLEIEPGKDFKYTAVFEVMPVFEIVELNQAPVELIRSEVTDKDVDNMIEKLREQNKEWHEVTHAVKK
GDKVVIDFQGFLDDKPFQGGSAEGYELVIGSGSMIPGFEDGIVGGKIDKPFDIKVSFPEDYGHKDLAGKEATFKITIKKI
MEGKLPALDEAFAEKFNIKEGGIESLKKDIRENMARELERRVNMMNREKLFDSLMSVNHVELPIALIDKEIEHLKHDMYH
RLFGHEHKDDEKIPDFPRELFEEQAKRRVHLGLLFAEYVKKHEIVADNDKVNAMIDKFASAYESPDELRAWYQSSKEHMA
EVEALVMEDMVADKIAEDAKLKYKNMDYDSVMNPKKGTEKKGE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=435, Percent_Identity=41.1494252873563, Blast_Score=343, Evalue=1e-95,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 50792; Mature: 50792

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSVETLEGLERKVTVSVPTEKVEEEVSSRLRNLARKVKIDGFRPGKVPFNVVKSRFSD
CCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
SVREEVAREMVQSTLYEALQKNELVPAGYPHVEPLEIEPGKDFKYTAVFEVMPVFEIVEL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
NQAPVELIRSEVTDKDVDNMIEKLREQNKEWHEVTHAVKKGDKVVIDFQGFLDDKPFQGG
CHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
SAEGYELVIGSGSMIPGFEDGIVGGKIDKPFDIKVSFPEDYGHKDLAGKEATFKITIKKI
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEHHHH
MEGKLPALDEAFAEKFNIKEGGIESLKKDIRENMARELERRVNMMNREKLFDSLMSVNHV
HCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ELPIALIDKEIEHLKHDMYHRLFGHEHKDDEKIPDFPRELFEEQAKRRVHLGLLFAEYVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KHEIVADNDKVNAMIDKFASAYESPDELRAWYQSSKEHMAEVEALVMEDMVADKIAEDAK
HCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKYKNMDYDSVMNPKKGTEKKGE
HHCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQVSVETLEGLERKVTVSVPTEKVEEEVSSRLRNLARKVKIDGFRPGKVPFNVVKSRFSD
CCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
SVREEVAREMVQSTLYEALQKNELVPAGYPHVEPLEIEPGKDFKYTAVFEVMPVFEIVEL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
NQAPVELIRSEVTDKDVDNMIEKLREQNKEWHEVTHAVKKGDKVVIDFQGFLDDKPFQGG
CHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
SAEGYELVIGSGSMIPGFEDGIVGGKIDKPFDIKVSFPEDYGHKDLAGKEATFKITIKKI
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEHHHH
MEGKLPALDEAFAEKFNIKEGGIESLKKDIRENMARELERRVNMMNREKLFDSLMSVNHV
HCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ELPIALIDKEIEHLKHDMYHRLFGHEHKDDEKIPDFPRELFEEQAKRRVHLGLLFAEYVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KHEIVADNDKVNAMIDKFASAYESPDELRAWYQSSKEHMAEVEALVMEDMVADKIAEDAK
HCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKYKNMDYDSVMNPKKGTEKKGE
HHCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA