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The map label for this gene is udk

Identifier: 52842080

GI number: 52842080

Start: 2075411

End: 2076133

Strand: Direct

Name: udk

Synonym: lpg1853

Alternate gene names: 52842080

Gene position: 2075411-2076133 (Clockwise)

Preceding gene: 52842079

Following gene: 52842081

Centisome position: 61.08

GC content: 37.76

Gene sequence:

>723_bases
ATGCTTTTCATAAGACTGGAGAGAATGATTGAATTCCAACTGAAAAAACTTTACTATTCGTACAAAATTTTTAATGAAAA
CATTATGACAAAGCAAGCAATTATTATTGGGATTTCCGGCCCATCAGCATCTGGAAAAAGTTTATTAGCAAATACTATAG
TCAATGAATTAGGATCCGAGCAGGTTGTCGTTATCTCTGAAGATGCCTACTATAAAGATAATGGGCATCTACCCTTTACA
GAGAGAGAAAAAATAAATTACGATCATCCTGACTCCTTTGATCATGCTCTACTTTATGAGCATCTTCGTCAGCTACGAGT
TGGAAATACAGTACAAATTCCTATTTATTCTCATTCCAAACATCTGCGTTTACCTGAAACCAGAGCAGTGGGTCAACATG
CCATTATTGTACTCGAAGGAATACTGCTTTTCAGTGATAAAGCTCTACGAGAAATTATGGATATACGTATATTCATGTCG
ACTCCTCTTGACGTCTGTTTAACGCGGCGCTTAAAAAGAGATGTAGTAGAAAGGCATCGATCATTTGAATCGGTTATTCA
TCAATATGAGACTACAGTTCGCCCTATGTACATGCAATTTATTGAGCCTTCAAGCCGCTACGCTGATATAATAGTACCTC
GCGGCGGTGAAAACAGAATCGCTATAGAGATGATTCAAGCTAAAATGCGGGAATTATTAGCTTCACATACTCGAGGCAGT
TGA

Upstream 100 bases:

>100_bases
AGGCAAGTACACACAACGGATATTGCACCAACATTATCTTCCTTATTATTGATTAAACCCCCTGCCGCAGCAGTAGGACA
GCCTTTAGTTGAAGTAGTCA

Downstream 100 bases:

>100_bases
TGTTTTATTAGGCTGTTTAAGAGCAACCTAATTGATATTGTGGTTTTAGTCCAGGATCGAAGTAACACTCACTTCGCCCT
GCTAAATTAAGAATAATGGG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MLFIRLERMIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSEQVVVISEDAYYKDNGHLPFT
EREKINYDHPDSFDHALLYEHLRQLRVGNTVQIPIYSHSKHLRLPETRAVGQHAIIVLEGILLFSDKALREIMDIRIFMS
TPLDVCLTRRLKRDVVERHRSFESVIHQYETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS

Sequences:

>Translated_240_residues
MLFIRLERMIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSEQVVVISEDAYYKDNGHLPFT
EREKINYDHPDSFDHALLYEHLRQLRVGNTVQIPIYSHSKHLRLPETRAVGQHAIIVLEGILLFSDKALREIMDIRIFMS
TPLDVCLTRRLKRDVVERHRSFESVIHQYETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS
>Mature_240_residues
MLFIRLERMIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSEQVVVISEDAYYKDNGHLPFT
EREKINYDHPDSFDHALLYEHLRQLRVGNTVQIPIYSHSKHLRLPETRAVGQHAIIVLEGILLFSDKALREIMDIRIFMS
TPLDVCLTRRLKRDVVERHRSFESVIHQYETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=210, Percent_Identity=40.4761904761905, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI57863312, Length=210, Percent_Identity=40.4761904761905, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI18699734, Length=211, Percent_Identity=36.4928909952607, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI13899253, Length=215, Percent_Identity=37.2093023255814, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI209863022, Length=184, Percent_Identity=33.695652173913, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI87082034, Length=208, Percent_Identity=54.8076923076923, Blast_Score=243, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI17539892, Length=206, Percent_Identity=39.3203883495146, Blast_Score=164, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17539894, Length=206, Percent_Identity=39.3203883495146, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71981181, Length=211, Percent_Identity=30.8056872037915, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6324339, Length=183, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=7e-28,
Organism=Drosophila melanogaster, GI45550449, Length=222, Percent_Identity=36.4864864864865, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28573516, Length=222, Percent_Identity=36.4864864864865, Blast_Score=151, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28573514, Length=222, Percent_Identity=36.4864864864865, Blast_Score=151, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28573512, Length=222, Percent_Identity=36.4864864864865, Blast_Score=151, Evalue=3e-37,
Organism=Drosophila melanogaster, GI221458995, Length=225, Percent_Identity=34.2222222222222, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24649624, Length=222, Percent_Identity=34.6846846846847, Blast_Score=146, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 27863; Mature: 27863

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFIRLERMIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSE
CEEEEHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCC
QVVVISEDAYYKDNGHLPFTEREKINYDHPDSFDHALLYEHLRQLRVGNTVQIPIYSHSK
EEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCC
HLRLPETRAVGQHAIIVLEGILLFSDKALREIMDIRIFMSTPLDVCLTRRLKRDVVERHR
CCCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
SFESVIHQYETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLFIRLERMIEFQLKKLYYSYKIFNENIMTKQAIIIGISGPSASGKSLLANTIVNELGSE
CEEEEHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCC
QVVVISEDAYYKDNGHLPFTEREKINYDHPDSFDHALLYEHLRQLRVGNTVQIPIYSHSK
EEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCC
HLRLPETRAVGQHAIIVLEGILLFSDKALREIMDIRIFMSTPLDVCLTRRLKRDVVERHR
CCCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
SFESVIHQYETTVRPMYMQFIEPSSRYADIIVPRGGENRIAIEMIQAKMRELLASHTRGS
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA