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The map label for this gene is trxB1

Identifier: 52841994

GI number: 52841994

Start: 1973921

End: 1974970

Strand: Direct

Name: trxB1

Synonym: lpg1767

Alternate gene names: 52841994

Gene position: 1973921-1974970 (Clockwise)

Preceding gene: 52841977

Following gene: 52841995

Centisome position: 58.09

GC content: 43.33

Gene sequence:

>1050_bases
CTGTTTTCCCGAATGTTGTTTTGCCATAGGTATTTTAATGTTTTTATTTTTGTCATAATATTTGCCATCTTAACACAAAA
AATAAGGAAGGCAGAGACAATGAGCATAAGCAATCACCATCGCTTAATCATACTCGGTTCAGGTCCTGCAGGTTACACTG
CTGCAGTCTATGCCGCAAGAGCCAATCTGAATCCCGTTTTGATCACCGGAATGCAGCCTGGCGGACAATTAACAACCACG
ACTGATGTAGACAACTGGCCCGGAGATATTGAAGGATTACAAGGCCCCGCCCTAATGGAGCGTATGCAAAAACACGCGGA
ACGCTTTGATACTCAAGTCATATTCGATCATATTGTCAAAGCTGATTTAGCGCAAGCTCCCTTTACACTACAAGGGGATA
GTACTACTTACACCTGCGATGCCTTGATTATTGCAACCGGAGCCTCTGCTCGTTATTTGGGATTACCCTCAGAAACGGCC
TACCAGGGGCGAGGTGTCTCAGCGTGTGCTACTTGCGATGGATTTTTTTATCGCAATAAAAGTGTTTGCGTTATTGGAGG
AGGCAATACTGCCGTTGAAGAAGCACTTTATTTATCAAATTTGGCATCTTCCGTTACTCTGATTCACAGACGAGACAGCT
TGCGTGCAGAAAAGATACTGCAGGATAAACTCTTTGAGAAAGCGCATTCCGGTAACATTAAAATAATATGGAACTCAACC
CTTGATGAAGTACTGGGCGATGGGAAAAAAGTCACAGGAGCCATGATTCGTAACCTTAAAACTGGTGAAACTGATCAACT
GGCAATGGATGGTATTTTTATAGCCATTGGACACACACCAAATACTGCAATATTTCAAGATCAGCTGGCTATGAGAGACG
GTTATATCTTGATTAAGTCAGGACTTGATGGAATGGCAACAAGCACTTCTGTTCCTGGAGTATTTGCTTGTGGCGACGTT
GCTGATCATGTTTATCGTCAAGCCATTACATCAGCAGGATTTGGGTGCATGGCAGCCCTGGATGCTGAAAAGTACCTGGA
TTCAATATAA

Upstream 100 bases:

>100_bases
ACAAGAGAACAAAAAGAGCTCCTGTCAAAATCAATATAAAACTCCCCTCACACAAGCGTTTTATTATAAAGCTCGGCATG
GATTTTTTAGGGATTCCAGC

Downstream 100 bases:

>100_bases
AATTGGCTTACGATAGCAACTATACTTTTCCTGACCCGGAAACCAGTGATAAACAGGGTTTATTAGCAATTGGGGGTGTT
TTGACCCCCAAGCGAGTTTT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MFSRMLFCHRYFNVFIFVIIFAILTQKIRKAETMSISNHHRLIILGSGPAGYTAAVYAARANLNPVLITGMQPGGQLTTT
TDVDNWPGDIEGLQGPALMERMQKHAERFDTQVIFDHIVKADLAQAPFTLQGDSTTYTCDALIIATGASARYLGLPSETA
YQGRGVSACATCDGFFYRNKSVCVIGGGNTAVEEALYLSNLASSVTLIHRRDSLRAEKILQDKLFEKAHSGNIKIIWNST
LDEVLGDGKKVTGAMIRNLKTGETDQLAMDGIFIAIGHTPNTAIFQDQLAMRDGYILIKSGLDGMATSTSVPGVFACGDV
ADHVYRQAITSAGFGCMAALDAEKYLDSI

Sequences:

>Translated_349_residues
MFSRMLFCHRYFNVFIFVIIFAILTQKIRKAETMSISNHHRLIILGSGPAGYTAAVYAARANLNPVLITGMQPGGQLTTT
TDVDNWPGDIEGLQGPALMERMQKHAERFDTQVIFDHIVKADLAQAPFTLQGDSTTYTCDALIIATGASARYLGLPSETA
YQGRGVSACATCDGFFYRNKSVCVIGGGNTAVEEALYLSNLASSVTLIHRRDSLRAEKILQDKLFEKAHSGNIKIIWNST
LDEVLGDGKKVTGAMIRNLKTGETDQLAMDGIFIAIGHTPNTAIFQDQLAMRDGYILIKSGLDGMATSTSVPGVFACGDV
ADHVYRQAITSAGFGCMAALDAEKYLDSI
>Mature_349_residues
MFSRMLFCHRYFNVFIFVIIFAILTQKIRKAETMSISNHHRLIILGSGPAGYTAAVYAARANLNPVLITGMQPGGQLTTT
TDVDNWPGDIEGLQGPALMERMQKHAERFDTQVIFDHIVKADLAQAPFTLQGDSTTYTCDALIIATGASARYLGLPSETA
YQGRGVSACATCDGFFYRNKSVCVIGGGNTAVEEALYLSNLASSVTLIHRRDSLRAEKILQDKLFEKAHSGNIKIIWNST
LDEVLGDGKKVTGAMIRNLKTGETDQLAMDGIFIAIGHTPNTAIFQDQLAMRDGYILIKSGLDGMATSTSVPGVFACGDV
ADHVYRQAITSAGFGCMAALDAEKYLDSI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=317, Percent_Identity=67.5078864353312, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI87081763, Length=327, Percent_Identity=34.5565749235474, Blast_Score=154, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=47.6780185758514, Blast_Score=280, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=46.8944099378882, Blast_Score=278, Evalue=1e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 37811; Mature: 37811

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSRMLFCHRYFNVFIFVIIFAILTQKIRKAETMSISNHHRLIILGSGPAGYTAAVYAAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCHHEEEEEE
ANLNPVLITGMQPGGQLTTTTDVDNWPGDIEGLQGPALMERMQKHAERFDTQVIFDHIVK
CCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADLAQAPFTLQGDSTTYTCDALIIATGASARYLGLPSETAYQGRGVSACATCDGFFYRNK
HHHHCCCEEEECCCCEEEEEEEEEEECCCEEEECCCCCCCCCCCCCEEEEECCCEEEECC
SVCVIGGGNTAVEEALYLSNLASSVTLIHRRDSLRAEKILQDKLFEKAHSGNIKIIWNST
CEEEEECCCHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
LDEVLGDGKKVTGAMIRNLKTGETDQLAMDGIFIAIGHTPNTAIFQDQLAMRDGYILIKS
HHHHHCCCCEEHHHHHHCCCCCCCCCEEECEEEEEECCCCCCHHHHHHHHHCCCEEEEEC
GLDGMATSTSVPGVFACGDVADHVYRQAITSAGFGCMAALDAEKYLDSI
CCCCCCCCCCCCCEEECHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHCC
>Mature Secondary Structure
MFSRMLFCHRYFNVFIFVIIFAILTQKIRKAETMSISNHHRLIILGSGPAGYTAAVYAAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCHHEEEEEE
ANLNPVLITGMQPGGQLTTTTDVDNWPGDIEGLQGPALMERMQKHAERFDTQVIFDHIVK
CCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADLAQAPFTLQGDSTTYTCDALIIATGASARYLGLPSETAYQGRGVSACATCDGFFYRNK
HHHHCCCEEEECCCCEEEEEEEEEEECCCEEEECCCCCCCCCCCCCEEEEECCCEEEECC
SVCVIGGGNTAVEEALYLSNLASSVTLIHRRDSLRAEKILQDKLFEKAHSGNIKIIWNST
CEEEEECCCHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
LDEVLGDGKKVTGAMIRNLKTGETDQLAMDGIFIAIGHTPNTAIFQDQLAMRDGYILIKS
HHHHHCCCCEEHHHHHHCCCCCCCCCEEECEEEEEECCCCCCHHHHHHHHHCCCEEEEEC
GLDGMATSTSVPGVFACGDVADHVYRQAITSAGFGCMAALDAEKYLDSI
CCCCCCCCCCCCCEEECHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]