| Definition | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome. |
|---|---|
| Accession | NC_002942 |
| Length | 3,397,754 |
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The map label for this gene is iolC [H]
Identifier: 52841879
GI number: 52841879
Start: 1824301
End: 1826187
Strand: Reverse
Name: iolC [H]
Synonym: lpg1651
Alternate gene names: 52841879
Gene position: 1826187-1824301 (Counterclockwise)
Preceding gene: 52841880
Following gene: 52841878
Centisome position: 53.75
GC content: 38.16
Gene sequence:
>1887_bases ATGAAACAGTTTCCCGGATTTTATTTTGATAAGAATAGAGCAATCGATTTGATTTGTATGGGACGCGTAGCAGTTGATCT CTACGCGGAGCAAATAGGATTGGATTTAAAGGATGTTGCAAGCTTTAAAAAATATTTGGGTGGTTGTGCAGGAAATATTG CCGTTGGAGCTGCCCGATTAGGATTAAAAAGCCAGATGTTTTCCTGTGTTGGCTCAGATGAGTTAGGTAAGTTTCTGAAA GAAGAACTGGAACGTGAGGGAGTTAATATTGAGTTATTATTGGAAACAGATAATCATTTAACTGGCCTTGTACTTTTGGG TATTAAGCCTCCCTCCAATTTCCCTCTGCTTTTTTATCGTAATGATTGCGCAGATATGCAGATTAAATCAGATCAAATTA GTTTTACTGATTTAAAAAATGCAAAGTCATTATTGATAACGGGAACAGGTTTATCCACAGAATCAATGAAAAATACTACC CTGGAAGTAGTTCATTTAGCCCGAAAAGCAGAAACGACAATAGTTTTTGATCTCGATTATAGACCTGTTCTTTGGCGGTT AACTGTGATTGGTAATGGGGAAAGTCGTTATTGCCAGAATGAATATGTAACTCAAGTGTATCAACAAATTTTGCCTTTAT GCGATTTGATTGTTGGGACTGAAGAGGAAATATGTATTGCAGGCGGTTCGAATGATATTGAAGTTTCATTAATCAATATC AGGCAGCGAACCGATGCGCCAATAGTTGTTAAATTAGGAGAGAAGGGTGCTCGTGTTCATTTTGGAGCAGACAAAGGTCT ATTACAGGCAAAATCTTTTCCTGTTGAAGTATTGAATGTTTTGGGAGCAGGTGATGGTTTTATGTCCGGGCTTTTAGCTG GTTTGCTGCAAGGAAAATCATGGGAGCAAGCAGTAACCTATGCTAATGCTTGTGGCGCCTTGGTCGTGACTCGTCATGGT TGCGCTCCTGCAATTCCATACAAGGAAGAATTGAACTATTTTATTCAAGAATATGATCATGAGCCTGAAATATGGAACAG CTCCCAGTTAACACAATTGCATGAGAAATTAAGTAAAAATCGAAAGACACAGTTGCTTATTAAAAATCCATGTGGATTTG CCGATGGTTTAAATTCGATTGTAACGATGCAAGACTCACCTACAGCAATGAGTTTTAGTTCCCTTAAATTAAATAAGGGG CAAAGCCACCAATTTAACTCGAGTTATGAATTTGCTGCCCTCTTAATGACAGGAAAAGTTGTTTTCCAGTATGGCTGTTA TAGCCAGGAGGTTGAACGTACAGATTATTTTTCTCAATCACCCTATGTCTTGCACTGCTCAAAGAATGAAGTAAGTTCAG TAATCGCTCTGACTGATTGTGAAATTTTATTAATGGAAACGGAAAACGAAAATTTATTTTCTCCGATTTTATTTGATGCA TCTAATATGCTTGAGTTAGACAATAGGGGAGAAGGAGTTCTTGAAAATACTTCATATCGACTTGTCAGAACGGTATTTGA TAAACGAAACAGACCCGAATCTAATTTGGTAGTTGGGGAAATTATTACGTTTCAAGGGCGTTGGTCAAGTTATCCTTCAC ATTATCATCAACAACCTGAAATTTACCACTACAGGTTTTCAGAGCCTCAAGGCTATGCTTTTGGCGAAAATGGTAAAGAG GTGATGCGAATTGAACACTATGATACCTACCAGATTGCCAATAATCAGGAACATGCTCATTGTACAGCGCCCGGTTATGC ACTTTATACACTGTGGTTTATCCGGCATTTAAATAATAACGCATATACCTTGCCTACCTTCACAAAAGACCATGAATGGA CAAGGACAAGCAGGGCAAATTTAAGAACATGGCAACATAAACAGTAG
Upstream 100 bases:
>100_bases CCCGTTTCAGGATTGGATGGACTACAAGCCTTGCGCATCGCAAAAGCAGCGAAACAATCTTTAGAAACGCATCTGCCAGT AGTATTGAGTTGAGGCCGCT
Downstream 100 bases:
>100_bases TAATCCTTATCTGCAGTATGATTTTGAGAGTCAAATAAATGAAGATTAAATTAACTATGGCTCAGGCCCTATTAAGATTT TTAGCTAATCAGTATGTCGT
Product: IolC/IolB transferase kinase protein
Products: NA
Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]
Number of amino acids: Translated: 628; Mature: 628
Protein sequence:
>628_residues MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARLGLKSQMFSCVGSDELGKFLK EELEREGVNIELLLETDNHLTGLVLLGIKPPSNFPLLFYRNDCADMQIKSDQISFTDLKNAKSLLITGTGLSTESMKNTT LEVVHLARKAETTIVFDLDYRPVLWRLTVIGNGESRYCQNEYVTQVYQQILPLCDLIVGTEEEICIAGGSNDIEVSLINI RQRTDAPIVVKLGEKGARVHFGADKGLLQAKSFPVEVLNVLGAGDGFMSGLLAGLLQGKSWEQAVTYANACGALVVTRHG CAPAIPYKEELNYFIQEYDHEPEIWNSSQLTQLHEKLSKNRKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKG QSHQFNSSYEFAALLMTGKVVFQYGCYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPEIYHYRFSEPQGYAFGENGKE VMRIEHYDTYQIANNQEHAHCTAPGYALYTLWFIRHLNNNAYTLPTFTKDHEWTRTSRANLRTWQHKQ
Sequences:
>Translated_628_residues MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARLGLKSQMFSCVGSDELGKFLK EELEREGVNIELLLETDNHLTGLVLLGIKPPSNFPLLFYRNDCADMQIKSDQISFTDLKNAKSLLITGTGLSTESMKNTT LEVVHLARKAETTIVFDLDYRPVLWRLTVIGNGESRYCQNEYVTQVYQQILPLCDLIVGTEEEICIAGGSNDIEVSLINI RQRTDAPIVVKLGEKGARVHFGADKGLLQAKSFPVEVLNVLGAGDGFMSGLLAGLLQGKSWEQAVTYANACGALVVTRHG CAPAIPYKEELNYFIQEYDHEPEIWNSSQLTQLHEKLSKNRKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKG QSHQFNSSYEFAALLMTGKVVFQYGCYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPEIYHYRFSEPQGYAFGENGKE VMRIEHYDTYQIANNQEHAHCTAPGYALYTLWFIRHLNNNAYTLPTFTKDHEWTRTSRANLRTWQHKQ >Mature_628_residues MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARLGLKSQMFSCVGSDELGKFLK EELEREGVNIELLLETDNHLTGLVLLGIKPPSNFPLLFYRNDCADMQIKSDQISFTDLKNAKSLLITGTGLSTESMKNTT LEVVHLARKAETTIVFDLDYRPVLWRLTVIGNGESRYCQNEYVTQVYQQILPLCDLIVGTEEEICIAGGSNDIEVSLINI RQRTDAPIVVKLGEKGARVHFGADKGLLQAKSFPVEVLNVLGAGDGFMSGLLAGLLQGKSWEQAVTYANACGALVVTRHG CAPAIPYKEELNYFIQEYDHEPEIWNSSQLTQLHEKLSKNRKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKG QSHQFNSSYEFAALLMTGKVVFQYGCYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPEIYHYRFSEPQGYAFGENGKE VMRIEHYDTYQIANNQEHAHCTAPGYALYTLWFIRHLNNNAYTLPTFTKDHEWTRTSRANLRTWQHKQ
Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]
COG id: COG0524
COG function: function code G; Sugar kinases, ribokinase family
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the carbohydrate kinase pfkB family [H]
Homologues:
Organism=Escherichia coli, GI87082281, Length=294, Percent_Identity=25.1700680272109, Blast_Score=70, Evalue=4e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011611 - InterPro: IPR002173 - InterPro: IPR022841 [H]
Pfam domain/function: PF00294 PfkB [H]
EC number: =2.7.1.92 [H]
Molecular weight: Translated: 70836; Mature: 70836
Theoretical pI: Translated: 5.85; Mature: 5.85
Prosite motif: PS00584 PFKB_KINASES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARL CCCCCCCEECCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHH GLKSQMFSCVGSDELGKFLKEELEREGVNIELLLETDNHLTGLVLLGIKPPSNFPLLFYR CHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCCCCCCEEEEE NDCADMQIKSDQISFTDLKNAKSLLITGTGLSTESMKNTTLEVVHLARKAETTIVFDLDY CCCCCCEEECCCEEEHCCCCCCEEEEEECCCCCCHHCCHHHHHHHHHHHCCEEEEEEECC RPVLWRLTVIGNGESRYCQNEYVTQVYQQILPLCDLIVGTEEEICIAGGSNDIEVSLINI CCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEE RQRTDAPIVVKLGEKGARVHFGADKGLLQAKSFPVEVLNVLGAGDGFMSGLLAGLLQGKS ECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCC WEQAVTYANACGALVVTRHGCAPAIPYKEELNYFIQEYDHEPEIWNSSQLTQLHEKLSKN HHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC RKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKGQSHQFNSSYEFAALLMTGKV CCEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEECEE VFQYGCYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA EEEECCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCEEEEEECCCCCCCCHHEECC SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPE CCEEEECCCCCCCEECCHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHCCCCC IYHYRFSEPQGYAFGENGKEVMRIEHYDTYQIANNQEHAHCTAPGYALYTLWFIRHLNNN EEEEEECCCCCCEECCCCCEEEEEECCCEEEECCCCCCEEECCCCHHHHHHHHHHHHCCC AYTLPTFTKDHEWTRTSRANLRTWQHKQ EEECCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MKQFPGFYFDKNRAIDLICMGRVAVDLYAEQIGLDLKDVASFKKYLGGCAGNIAVGAARL CCCCCCCEECCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHH GLKSQMFSCVGSDELGKFLKEELEREGVNIELLLETDNHLTGLVLLGIKPPSNFPLLFYR CHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCCCCCCEEEEE NDCADMQIKSDQISFTDLKNAKSLLITGTGLSTESMKNTTLEVVHLARKAETTIVFDLDY CCCCCCEEECCCEEEHCCCCCCEEEEEECCCCCCHHCCHHHHHHHHHHHCCEEEEEEECC RPVLWRLTVIGNGESRYCQNEYVTQVYQQILPLCDLIVGTEEEICIAGGSNDIEVSLINI CCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEEE RQRTDAPIVVKLGEKGARVHFGADKGLLQAKSFPVEVLNVLGAGDGFMSGLLAGLLQGKS ECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCC WEQAVTYANACGALVVTRHGCAPAIPYKEELNYFIQEYDHEPEIWNSSQLTQLHEKLSKN HHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC RKTQLLIKNPCGFADGLNSIVTMQDSPTAMSFSSLKLNKGQSHQFNSSYEFAALLMTGKV CCEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEECEE VFQYGCYSQEVERTDYFSQSPYVLHCSKNEVSSVIALTDCEILLMETENENLFSPILFDA EEEECCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCEEEEEECCCCCCCCHHEECC SNMLELDNRGEGVLENTSYRLVRTVFDKRNRPESNLVVGEIITFQGRWSSYPSHYHQQPE CCEEEECCCCCCCEECCHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHCCCCC IYHYRFSEPQGYAFGENGKEVMRIEHYDTYQIANNQEHAHCTAPGYALYTLWFIRHLNNN EEEEEECCCCCCEECCCCCEEEEEECCCEEEECCCCCCEEECCCCHHHHHHHHHHHHCCC AYTLPTFTKDHEWTRTSRANLRTWQHKQ EEECCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12552129 [H]