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The map label for this gene is yuxL [H]

Identifier: 52841869

GI number: 52841869

Start: 1813262

End: 1815241

Strand: Reverse

Name: yuxL [H]

Synonym: lpg1641

Alternate gene names: 52841869

Gene position: 1815241-1813262 (Counterclockwise)

Preceding gene: 52841870

Following gene: 52841867

Centisome position: 53.42

GC content: 38.48

Gene sequence:

>1980_bases
ATGATTGTCATGAAGGGGGTATGCCTGGGTCTAATTATTTGTCTTGTTGTATTTCATGATGGATGGGCTGGGAAGCGTTT
GCCAGAGCTTGATGATCTTTATCGTATACAAGATATCAGCGAGCCAGATCTGTCACCAGATGGAAAATGGGTTGCCTATA
CCGTATCCCAATTAAATGCCAAAGATAACATTTCCACGACTGAGGTATGGAAAGTATCAGTGGATAGTAAATCCAGTCAA
CGAATTACCTTTGCAGAAGATTCATCAAGCTCGCTACCCAAATGGAGTCCTAATGGTAAATGGTTAGCTTATTTATCCGA
TGGCGGAAAAGAGGGTACGACACAAATTTGGATAGCATCTGTCCAGGATAATAAAGAACATCAATTAACTCATATTGATG
GCGAAGTGAGCGATTTTACATGGTCTCCAGATTCTAACAGGATTGCATTTATAGCTCAGAAGAGTGTTCCATCTAATGAG
GAAGAACAACCCATAGTTGTAGATAGATATCAATTTAAGGTTGATGGTGTCGGTTATCTTGGTAAGGGAAGAGATCATTT
ATATTTGGTTGAACTTAAGAGTAAGGCTATTACTCAACTGACCGATGGAAATCATGATGAATATTTACCGGCTTGGTCAC
CTGATGGAAAATACATCGCGTTTGTCACAAAGCGTGGAAAAGATCCGGATAGGCATTTTAATTATGATATTTATTTGATC
GAACCCAAGTCTGGGGCAAAAGAGCGCCAACTCACTCATTTCTCCGGTAGTGATATGAATCCTGATTACGATTCAAATCT
TTCATGGAGCCCAGATAGTTCAAAAATAGCTTATCTTCGCAGTAATGAACATCAATGGACCTATTATTCGCCCAATCAAT
TGGCAATTATTGATATCAATACTAAAGATGAGAAAATCATTGCACCTCGGGATAATTGGTATTACAAGCCAAAATGGTCT
CAAGATGGCAAATTTATTTATGCATTAATAGAAGAAAGCAGAAACACCTATTTGAATCGCATAGACACTCATTCCGGCCA
GATAAAAAAATTGACAGGCGGCTTACGCTATGACATGGATTATTCACTTGCCAAAGGGAAAATTATTTTGTTAACAACAG
ATGATACACATCCCTCTGAATTATTTATTTTGAATTCCGGATTAATTCCTTTAACACAACATAATAAAAAGCTATTGGAT
GAAGTTAAATTTCAACCCGCAGAAGACATACAGTGCAATAGCTTTGATGGAACAAGAGTTGATGGATTATTAATGAAGCC
AGCTGAATACCAGTCGGGTATTTTATTTCCTGGTTTTGTCTATCTGCATGGAGGACCAGTCTATCAATTTAGCCATGAAT
TTAACTTTGATATGCAGTGGCTGGTAGCTAATAATTATGTCGTTATTGCTCCTAATCCAAGAGGGAGTTCCGGAAGGGGA
TTTCATTATGCCAAAGCAATTTTTGCAGATTGGGGTAATTTGGATGTAAAAGACGTCTTGGCTTCTGTTGATTATGTCAT
AGGTAAGGGAATGGTCGATCCAAATCGTCTGGGAATAGGCGGATGGAGCTACGGAGGAATGCTAACCAATTATGTCATAG
CTACAGATAGCCGTTTCAAGGCGGCTATATCAGGTGCTGGAGCAGCGAATATTTTAGCTGGTTATGGTGTCGATCAATAC
ACCCCGGAATACGAGCTGGAATTGGGAAAGCCTTGGACCAATCCTAAATTGTATTTAAAATTAAGCTACCCTTTTCTTAA
AGCGAATAATATAAAAACACCTACATTATTTTTGTGCAGTGGCTTGGATGTTAATGTCCCTTGTGTTGGGTCAGAACAAT
TATACCAATCCTTGAAATCGCTAGATGTGCCAACACAGTTAGTTATTTACCCCAATGAATATCATACTTTGGAGAAACCA
AGCTTTGTCATCGACAGATTAAAAAGATATACCAACTGGCTAGATGCTTATGTTAAATAG

Upstream 100 bases:

>100_bases
CTCAAAATTTGTTTGCTGATTGCCGGAAAAATCATATATAACAAATTTATTCTATACTTTTTAAGGCACTATAAATCTCT
GATTTTTCAGCATAATAAGG

Downstream 100 bases:

>100_bases
CAATCCTGCCTAGTCGGTCAAAACAAGATGGTAATGAGTCCAATAATTAAAAAAGCGCATGCAGCTACAGCATGAATTAT
TTTCATGGGAATTTTATGGG

Product: acylaminoacyl peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MIVMKGVCLGLIICLVVFHDGWAGKRLPELDDLYRIQDISEPDLSPDGKWVAYTVSQLNAKDNISTTEVWKVSVDSKSSQ
RITFAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQDNKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSVPSNE
EEQPIVVDRYQFKVDGVGYLGKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLI
EPKSGAKERQLTHFSGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKDEKIIAPRDNWYYKPKWS
QDGKFIYALIEESRNTYLNRIDTHSGQIKKLTGGLRYDMDYSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLD
EVKFQPAEDIQCNSFDGTRVDGLLMKPAEYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWLVANNYVVIAPNPRGSSGRG
FHYAKAIFADWGNLDVKDVLASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAISGAGAANILAGYGVDQY
TPEYELELGKPWTNPKLYLKLSYPFLKANNIKTPTLFLCSGLDVNVPCVGSEQLYQSLKSLDVPTQLVIYPNEYHTLEKP
SFVIDRLKRYTNWLDAYVK

Sequences:

>Translated_659_residues
MIVMKGVCLGLIICLVVFHDGWAGKRLPELDDLYRIQDISEPDLSPDGKWVAYTVSQLNAKDNISTTEVWKVSVDSKSSQ
RITFAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQDNKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSVPSNE
EEQPIVVDRYQFKVDGVGYLGKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLI
EPKSGAKERQLTHFSGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKDEKIIAPRDNWYYKPKWS
QDGKFIYALIEESRNTYLNRIDTHSGQIKKLTGGLRYDMDYSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLD
EVKFQPAEDIQCNSFDGTRVDGLLMKPAEYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWLVANNYVVIAPNPRGSSGRG
FHYAKAIFADWGNLDVKDVLASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAISGAGAANILAGYGVDQY
TPEYELELGKPWTNPKLYLKLSYPFLKANNIKTPTLFLCSGLDVNVPCVGSEQLYQSLKSLDVPTQLVIYPNEYHTLEKP
SFVIDRLKRYTNWLDAYVK
>Mature_659_residues
MIVMKGVCLGLIICLVVFHDGWAGKRLPELDDLYRIQDISEPDLSPDGKWVAYTVSQLNAKDNISTTEVWKVSVDSKSSQ
RITFAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIASVQDNKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSVPSNE
EEQPIVVDRYQFKVDGVGYLGKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLI
EPKSGAKERQLTHFSGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDINTKDEKIIAPRDNWYYKPKWS
QDGKFIYALIEESRNTYLNRIDTHSGQIKKLTGGLRYDMDYSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLD
EVKFQPAEDIQCNSFDGTRVDGLLMKPAEYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWLVANNYVVIAPNPRGSSGRG
FHYAKAIFADWGNLDVKDVLASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFKAAISGAGAANILAGYGVDQY
TPEYELELGKPWTNPKLYLKLSYPFLKANNIKTPTLFLCSGLDVNVPCVGSEQLYQSLKSLDVPTQLVIYPNEYHTLEKP
SFVIDRLKRYTNWLDAYVK

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI37577089, Length=246, Percent_Identity=30.0813008130081, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI23510451, Length=706, Percent_Identity=21.8130311614731, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI18450280, Length=246, Percent_Identity=30.0813008130081, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI194394146, Length=246, Percent_Identity=29.6747967479675, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17552908, Length=275, Percent_Identity=25.4545454545455, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17564632, Length=224, Percent_Identity=29.9107142857143, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17564634, Length=224, Percent_Identity=29.9107142857143, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25144537, Length=237, Percent_Identity=27.0042194092827, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144540, Length=237, Percent_Identity=27.0042194092827, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17550672, Length=236, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25149159, Length=370, Percent_Identity=24.3243243243243, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508019, Length=224, Percent_Identity=29.0178571428571, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508017, Length=224, Percent_Identity=29.0178571428571, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550825, Length=231, Percent_Identity=28.1385281385281, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45553511, Length=231, Percent_Identity=28.1385281385281, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45551969, Length=231, Percent_Identity=28.1385281385281, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 74503; Mature: 74503

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVMKGVCLGLIICLVVFHDGWAGKRLPELDDLYRIQDISEPDLSPDGKWVAYTVSQLNA
CEEECHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEECCC
KDNISTTEVWKVSVDSKSSQRITFAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIAS
CCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEE
VQDNKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSVPSNEEEQPIVVDRYQFKVDGVGYL
ECCCCCCEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCEEEE
GKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLI
CCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHCCEEEEEE
EPKSGAKERQLTHFSGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDIN
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEEEEC
TKDEKIIAPRDNWYYKPKWSQDGKFIYALIEESRNTYLNRIDTHSGQIKKLTGGLRYDMD
CCCCEEECCCCCCEECCCCCCCCCEEEEEEECCCCHHHHEECCCCCCEEEECCCEEECCC
YSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLDEVKFQPAEDIQCNSFDGTRV
CEECCCEEEEEECCCCCCCEEEEEECCCEEECCCCHHHHHHHCCCCCCCCEECCCCCCCC
DGLLMKPAEYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWLVANNYVVIAPNPRGSSGRG
CEEEECCCHHCCCEECCCEEEEECCEEEEEECCCCCCEEEEEECCEEEEECCCCCCCCCC
FHYAKAIFADWGNLDVKDVLASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFK
EEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCEEEEEEEEECCCEE
AAISGAGAANILAGYGVDQYTPEYELELGKPWTNPKLYLKLSYPFLKANNIKTPTLFLCS
EEECCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEECCCCCCCEEEEEC
GLDVNVPCVGSEQLYQSLKSLDVPTQLVIYPNEYHTLEKPSFVIDRLKRYTNWLDAYVK
CCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVMKGVCLGLIICLVVFHDGWAGKRLPELDDLYRIQDISEPDLSPDGKWVAYTVSQLNA
CEEECHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEECCC
KDNISTTEVWKVSVDSKSSQRITFAEDSSSSLPKWSPNGKWLAYLSDGGKEGTTQIWIAS
CCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEE
VQDNKEHQLTHIDGEVSDFTWSPDSNRIAFIAQKSVPSNEEEQPIVVDRYQFKVDGVGYL
ECCCCCCEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCEEEE
GKGRDHLYLVELKSKAITQLTDGNHDEYLPAWSPDGKYIAFVTKRGKDPDRHFNYDIYLI
CCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHCCEEEEEE
EPKSGAKERQLTHFSGSDMNPDYDSNLSWSPDSSKIAYLRSNEHQWTYYSPNQLAIIDIN
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEEEEC
TKDEKIIAPRDNWYYKPKWSQDGKFIYALIEESRNTYLNRIDTHSGQIKKLTGGLRYDMD
CCCCEEECCCCCCEECCCCCCCCCEEEEEEECCCCHHHHEECCCCCCEEEECCCEEECCC
YSLAKGKIILLTTDDTHPSELFILNSGLIPLTQHNKKLLDEVKFQPAEDIQCNSFDGTRV
CEECCCEEEEEECCCCCCCEEEEEECCCEEECCCCHHHHHHHCCCCCCCCEECCCCCCCC
DGLLMKPAEYQSGILFPGFVYLHGGPVYQFSHEFNFDMQWLVANNYVVIAPNPRGSSGRG
CEEEECCCHHCCCEECCCEEEEECCEEEEEECCCCCCEEEEEECCEEEEECCCCCCCCCC
FHYAKAIFADWGNLDVKDVLASVDYVIGKGMVDPNRLGIGGWSYGGMLTNYVIATDSRFK
EEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCEEEEEEEEECCCEE
AAISGAGAANILAGYGVDQYTPEYELELGKPWTNPKLYLKLSYPFLKANNIKTPTLFLCS
EEECCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEECCCCCCCEEEEEC
GLDVNVPCVGSEQLYQSLKSLDVPTQLVIYPNEYHTLEKPSFVIDRLKRYTNWLDAYVK
CCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]