Click here to switch to the map view.

The map label for this gene is engA

Identifier: 52841771

GI number: 52841771

Start: 1705239

End: 1706627

Strand: Reverse

Name: engA

Synonym: lpg1541

Alternate gene names: 52841771

Gene position: 1706627-1705239 (Counterclockwise)

Preceding gene: 52841772

Following gene: 52841767

Centisome position: 50.23

GC content: 36.5

Gene sequence:

>1389_bases
ATGATCCCTGTTATCGCTTTAGTTGGGCGTCCCAATGTTGGAAAGTCTACTTTGTTTAATAGAATTACTAAAACGCAGGA
TGCTCTTGTCGCAGATTTTCCTGGCTTGACAAGGGATAGACAATATGGACACGCTCAACATGAAAACAAGTCCTTTATTA
TTGTTGATACCGGAGGCATAGGAGTTGATGACATTGAAGTAGATACTTTGATGTCAAGACAGTCTCAAGTTGCTTTAAAC
GAAGCAAATGTGATTCTTTTCTTGGTGGATGGCCGTTCAGGACTAACAGGTATAGATCAGCAAATTGCACAAGCATTAAG
AAAATTTAATAAAAAAGTACATCTTGTTGTCAATAAAACAGATGGAATGAATGAAGATATTGCTTGTGCCGATTTTCAAT
CATTAGGCATTACTGATATACATGCTATATCTGCATCTCATGGTGGAGGCATCAGTTCACTACTCGAAGAAATTCTCGAG
CCATTTACAACAGAAACGCATGAAGCAACTGATGATAAAGCGATCAAAATTGCTTTTGCGGGGCGCCCTAACGTTGGAAA
ATCAACTTTGATAAACAGGATATTAGGGGAAGAAAGAGTAGTTGTTTATGATATGCCCGGAACAACTCGAGATAGTATTT
CAATACCCTTTACAAGAGAAGATAAGCAATATGTGCTTATTGATACTGCTGGTGTACGGCGTAAGTCTCGAATTGATGAA
AAAATAGAAAAGTTTTCTGTCATCAAAACTCTGCAAGCTATAAAAGAAGCTCATGTCTGTTTGTTACTTCTTGATGCAAA
TGAAGGCATTACCGATCAAGATATGAATTTGCTCGGTTTTATTATTGAATCTGGTAAAGCACTAGTTATTGCTGTGAATA
AATGGGATGGCCTGGAAGAAGATCATAAAGAAAAAATAAAGTCAGAACTGTCAAGAAGGTTGCATTTTGCAAATTTTGCA
AAAATAAGATTTATTTCAGCATTGCATGGGAGCGGGGTAGGTGGATTATTTAAAGATATTAATGAAGCCTATCATTCAGC
AATACAATCCTTTTCTACTCCAAAACTAACCAGATTATTACAAGATATCAGCGCAAAGCATACACCACCATGCATCAATG
GCCGACGAATAAAATTACGCTATGCTCACCTTGGCGGACACAATCCTCCAGTCATTGTTATTCATGGAAATCAACTCGAT
GCCTTGCCAGAAAGTTATAAACGTTATTTAAACAATGAGTTTATTAAGCATTTAGGATTAGTAGGTACTCCTTTAAAAAT
CGAGTTTAAAGGAGGTCAAAATCCATTTGCCAATAAAAAAAATAAATTATCACAAAGGCAAGTGAACAAGAAGAAACGAT
TAATGCGATGGGCAAAAAGCAAGAAATAG

Upstream 100 bases:

>100_bases
CTTTCTGGTGGAGTAACAGTATCACCGAGTGTTTCTGGTAAAAATATGTATGTATTAACCAATAATGGAATGCTCAATCA
ACTTTCAGTGAGCTAATAAA

Downstream 100 bases:

>100_bases
CACTCCGGTTCACCTCAGCCAGGTTTAAATTGTTCTAATGAAAAAAGGTACTAATCTCTTCTTATTAATCTGCTTTGAGT
GTTAATACATCACAAACCGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGIGVDDIEVDTLMSRQSQVALN
EANVILFLVDGRSGLTGIDQQIAQALRKFNKKVHLVVNKTDGMNEDIACADFQSLGITDIHAISASHGGGISSLLEEILE
PFTTETHEATDDKAIKIAFAGRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEEDHKEKIKSELSRRLHFANFA
KIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLLQDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLD
ALPESYKRYLNNEFIKHLGLVGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK

Sequences:

>Translated_462_residues
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGIGVDDIEVDTLMSRQSQVALN
EANVILFLVDGRSGLTGIDQQIAQALRKFNKKVHLVVNKTDGMNEDIACADFQSLGITDIHAISASHGGGISSLLEEILE
PFTTETHEATDDKAIKIAFAGRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEEDHKEKIKSELSRRLHFANFA
KIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLLQDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLD
ALPESYKRYLNNEFIKHLGLVGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK
>Mature_462_residues
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGIGVDDIEVDTLMSRQSQVALN
EANVILFLVDGRSGLTGIDQQIAQALRKFNKKVHLVVNKTDGMNEDIACADFQSLGITDIHAISASHGGGISSLLEEILE
PFTTETHEATDDKAIKIAFAGRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEEDHKEKIKSELSRRLHFANFA
KIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLLQDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLD
ALPESYKRYLNNEFIKHLGLVGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=490, Percent_Identity=55.5102040816327, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI2367268, Length=95, Percent_Identity=34.7368421052632, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788919, Length=177, Percent_Identity=28.2485875706215, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=179, Percent_Identity=29.608938547486, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51359; Mature: 51359

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
GVDDIEVDTLMSRQSQVALNEANVILFLVDGRSGLTGIDQQIAQALRKFNKKVHLVVNKT
CCCCCHHHHHHHCCHHEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECC
DGMNEDIACADFQSLGITDIHAISASHGGGISSLLEEILEPFTTETHEATDDKAIKIAFA
CCCCCCCEECCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
GRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEECCEECCCCCEEEEECCCCCHHHHHHH
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEE
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCH
DHKEKIKSELSRRLHFANFAKIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLL
HHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
QDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLDALPESYKRYLNNEFIKHLGL
HHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
VGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
GVDDIEVDTLMSRQSQVALNEANVILFLVDGRSGLTGIDQQIAQALRKFNKKVHLVVNKT
CCCCCHHHHHHHCCHHEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECC
DGMNEDIACADFQSLGITDIHAISASHGGGISSLLEEILEPFTTETHEATDDKAIKIAFA
CCCCCCCEECCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
GRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEECCEECCCCCEEEEECCCCCHHHHHHH
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEE
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCH
DHKEKIKSELSRRLHFANFAKIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLL
HHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
QDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLDALPESYKRYLNNEFIKHLGL
HHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
VGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA