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The map label for this gene is udp [H]

Identifier: 52841646

GI number: 52841646

Start: 1562840

End: 1563721

Strand: Direct

Name: udp [H]

Synonym: lpg1416

Alternate gene names: 52841646

Gene position: 1562840-1563721 (Clockwise)

Preceding gene: 52841644

Following gene: 52841647

Centisome position: 46.0

GC content: 39.68

Gene sequence:

>882_bases
ATGATAACTCCAGCCGAATTACCTATCAATCATCGTGGTGCGGTATATCATCTTGATTTAAGAACAGAGGAAATAGCTGA
TCTCATCATTACAGTGGGAGACCCTGGGCGAGTAAGCCTGGTTAGTCAACATTTTGATAAAATTGAAGTGCAACGCTCCC
ACCGAGAATTTGTTACTCATACAGGGTATCTGGGAACTAATAGAATTACAGTTCTCTCAACTGGAATTGGCATGCCAAAC
ATAGATATCGTGATGAATGAACTGGATGCTTTGGCAAACATCGATTTATCTACACGAACAGTGAATACCACCAAAAAAAG
TTTAACAATAATTCGATTAGGCACGACAGGAGCTCTGACTGAGAATTGTTTGCCCGGAGATATAGCCATTAGTCGATATG
CAATTGGTTTTGATAGTTTGATTGATTATTATCAATATCAGCCACTGGGAGTGCTTGAAACAATCAAGGAGGAATTATCT
CAATATTTAAAGGGAGAGAGTGGTCCGTTTTATATTTCTGAATCTTGCTCTCAATTAGCTGAACAGTTCAGCTCCTTGGG
ACATACAGGAATTACTGCTACTTGTGGTGGTTTTTATGGGCCGCAAGGTCGCCAGTTAAGATTGCCGCTTCATTACCCCA
ACCTTATTAGACAGTTAGGAACATTTTGCACTCAGAATTATTCAGTAATTAATCTTGAGATGGAAACTGCTGCTATCTAT
GCTCTTGGCAGTATGCTTGGACATAAATGCCTATCCTTAAGTGTGGTGATTAATAACAGGATACATGGAAGTTTTGCAGC
AGATGTGAAATCTTGCCTGGATTCCCTGATCACAAAATCACTCGCGAACATTAAAAATATCCTTGAGCTATCCGAAGCTT
AA

Upstream 100 bases:

>100_bases
TCCAATATTAATTAAATATTCAAATAATTTAGATCATTTGCAACCGTATACATTGATTATATATTATGGTTTACAAATTT
GAGGAATAATAGAAAAAAAA

Downstream 100 bases:

>100_bases
GGTGATTTAATTAAGACGCCCAGTGTGGTATCCTTTTGCATTAAATTAATCTTAATTTACTGTCTAAAGGATACATCCAA
ATTATGGTATACCTAGCCAA

Product: purine nucleoside phosphorylase II

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MITPAELPINHRGAVYHLDLRTEEIADLIITVGDPGRVSLVSQHFDKIEVQRSHREFVTHTGYLGTNRITVLSTGIGMPN
IDIVMNELDALANIDLSTRTVNTTKKSLTIIRLGTTGALTENCLPGDIAISRYAIGFDSLIDYYQYQPLGVLETIKEELS
QYLKGESGPFYISESCSQLAEQFSSLGHTGITATCGGFYGPQGRQLRLPLHYPNLIRQLGTFCTQNYSVINLEMETAAIY
ALGSMLGHKCLSLSVVINNRIHGSFAADVKSCLDSLITKSLANIKNILELSEA

Sequences:

>Translated_293_residues
MITPAELPINHRGAVYHLDLRTEEIADLIITVGDPGRVSLVSQHFDKIEVQRSHREFVTHTGYLGTNRITVLSTGIGMPN
IDIVMNELDALANIDLSTRTVNTTKKSLTIIRLGTTGALTENCLPGDIAISRYAIGFDSLIDYYQYQPLGVLETIKEELS
QYLKGESGPFYISESCSQLAEQFSSLGHTGITATCGGFYGPQGRQLRLPLHYPNLIRQLGTFCTQNYSVINLEMETAAIY
ALGSMLGHKCLSLSVVINNRIHGSFAADVKSCLDSLITKSLANIKNILELSEA
>Mature_293_residues
MITPAELPINHRGAVYHLDLRTEEIADLIITVGDPGRVSLVSQHFDKIEVQRSHREFVTHTGYLGTNRITVLSTGIGMPN
IDIVMNELDALANIDLSTRTVNTTKKSLTIIRLGTTGALTENCLPGDIAISRYAIGFDSLIDYYQYQPLGVLETIKEELS
QYLKGESGPFYISESCSQLAEQFSSLGHTGITATCGGFYGPQGRQLRLPLHYPNLIRQLGTFCTQNYSVINLEMETAAIY
ALGSMLGHKCLSLSVVINNRIHGSFAADVKSCLDSLITKSLANIKNILELSEA

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=255, Percent_Identity=28.6274509803922, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 32125; Mature: 32125

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITPAELPINHRGAVYHLDLRTEEIADLIITVGDPGRVSLVSQHFDKIEVQRSHREFVTH
CCCCCCCCCCCCCEEEEEECCHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TGYLGTNRITVLSTGIGMPNIDIVMNELDALANIDLSTRTVNTTKKSLTIIRLGTTGALT
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHEEEEEEECCCCCCC
ENCLPGDIAISRYAIGFDSLIDYYQYQPLGVLETIKEELSQYLKGESGPFYISESCSQLA
CCCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHH
EQFSSLGHTGITATCGGFYGPQGRQLRLPLHYPNLIRQLGTFCTQNYSVINLEMETAAIY
HHHHHCCCCCCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEEHHHHHH
ALGSMLGHKCLSLSVVINNRIHGSFAADVKSCLDSLITKSLANIKNILELSEA
HHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITPAELPINHRGAVYHLDLRTEEIADLIITVGDPGRVSLVSQHFDKIEVQRSHREFVTH
CCCCCCCCCCCCCEEEEEECCHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TGYLGTNRITVLSTGIGMPNIDIVMNELDALANIDLSTRTVNTTKKSLTIIRLGTTGALT
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHEEEEEEECCCCCCC
ENCLPGDIAISRYAIGFDSLIDYYQYQPLGVLETIKEELSQYLKGESGPFYISESCSQLA
CCCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHH
EQFSSLGHTGITATCGGFYGPQGRQLRLPLHYPNLIRQLGTFCTQNYSVINLEMETAAIY
HHHHHCCCCCCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEEHHHHHH
ALGSMLGHKCLSLSVVINNRIHGSFAADVKSCLDSLITKSLANIKNILELSEA
HHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]