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The map label for this gene is ribD

Identifier: 52841411

GI number: 52841411

Start: 1302987

End: 1304060

Strand: Direct

Name: ribD

Synonym: lpg1177

Alternate gene names: 52841411

Gene position: 1302987-1304060 (Clockwise)

Preceding gene: 52841408

Following gene: 52841412

Centisome position: 38.35

GC content: 42.55

Gene sequence:

>1074_bases
ATGCACGAACAGTTTCTGCTTGCAGCACTTGAACAAGCCAAACTGGGGAGAGGCTTTTGTGCCCCCAATCCCAGCGTTGG
GGCGGTTGCTGTGCAAAATGGTAATATTATAGCACAGGCATGGCATAGAGGTGCAGGTACACCGCATGCAGAACAATTAT
TGTTATCACAAATTCCACCCCAAACGCCAGGGGTTACGCTTTATGTCACGCTGGAGCCTTGTAATCATTGGGGCAAAACT
CCCCCTTGTGTTGATGCTATTATCAATCATGGTATAGAGGAGGTTGTTTTTTCCTATTTTGATCCAAACCCCATTGTTGC
CAAAAGTAACTCCTCAGAAAAATTACGTGAACATGGAATACAAGTCAGGCATATTCCTGTAAAGGCAATTGATGTGTTCT
ATAAAAGCTATGCTTATTGGACTATGACCCATAAACCAAGAGTCACTGTTAAAATAGCACAAACTTTTGATGGTAAAATT
GGAAAGTCTGAGGGAGCTCGAGTGGTTTTGTCCAATGCTTTATGCGAACAGTTCACTCATCAAATGCGTGCTGCCAGTGA
TGTCATATTAACCAGTGCCAAGACAGTTCAAATGGATAATCCAAGAATGAACGCCAGATTAGATAGTGGATTGGTAGCAA
AGCCAGTTGCCATTGTTGACCGCAATTTAAGTTTGTCTGATGACACAATCATTTTTTCGACAGCAAAACATTGCCACATT
TATCATCAACCACAAGCAAATCAGGCAAAGACTTATCCTAATAGCACTCATTATGCGATGCCTTTGCAAAATGGGTTGAT
GGACCTGGAGGCAATAATAACTCATCTTGGTCAACTGGGATATCATGACGTATGGGTTGAGGCGGGCGGAGCTATTTTTT
CTGCGTTACATAGTAAGGGATTGGTGCATAGAACCTATTTGTATTTAGTTCCCGGCAGTTTAGGGCATCAAGCGATTTCA
GCTTATCAACAACAGGGGATTTTTGAAAAAGCTCATACGGTGAGTTGGCAAGCTATGGGTGACAATATGATAGCATGTTT
GGATTGGCAGGAGGATGAGTGTTTACCGGATTGA

Upstream 100 bases:

>100_bases
TTCGTGATTAACTTATAATTTAAGTTCAATTTAATCATTAGGCTACTCAATAATTGAATAATTTGTTATCATTCGACCAC
ATTAAGAAGGTGGTTAATAT

Downstream 100 bases:

>100_bases
TAGAAAATACAGGCAAAGTATTAATGAATAGGCAAGGAGAAAATTCTAGTCGTTTAGTCGTATCTTCAAGCTATCAGGAT
TTGAAACCTGGTGAGAGTAT

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MHEQFLLAALEQAKLGRGFCAPNPSVGAVAVQNGNIIAQAWHRGAGTPHAEQLLLSQIPPQTPGVTLYVTLEPCNHWGKT
PPCVDAIINHGIEEVVFSYFDPNPIVAKSNSSEKLREHGIQVRHIPVKAIDVFYKSYAYWTMTHKPRVTVKIAQTFDGKI
GKSEGARVVLSNALCEQFTHQMRAASDVILTSAKTVQMDNPRMNARLDSGLVAKPVAIVDRNLSLSDDTIIFSTAKHCHI
YHQPQANQAKTYPNSTHYAMPLQNGLMDLEAIITHLGQLGYHDVWVEAGGAIFSALHSKGLVHRTYLYLVPGSLGHQAIS
AYQQQGIFEKAHTVSWQAMGDNMIACLDWQEDECLPD

Sequences:

>Translated_357_residues
MHEQFLLAALEQAKLGRGFCAPNPSVGAVAVQNGNIIAQAWHRGAGTPHAEQLLLSQIPPQTPGVTLYVTLEPCNHWGKT
PPCVDAIINHGIEEVVFSYFDPNPIVAKSNSSEKLREHGIQVRHIPVKAIDVFYKSYAYWTMTHKPRVTVKIAQTFDGKI
GKSEGARVVLSNALCEQFTHQMRAASDVILTSAKTVQMDNPRMNARLDSGLVAKPVAIVDRNLSLSDDTIIFSTAKHCHI
YHQPQANQAKTYPNSTHYAMPLQNGLMDLEAIITHLGQLGYHDVWVEAGGAIFSALHSKGLVHRTYLYLVPGSLGHQAIS
AYQQQGIFEKAHTVSWQAMGDNMIACLDWQEDECLPD
>Mature_357_residues
MHEQFLLAALEQAKLGRGFCAPNPSVGAVAVQNGNIIAQAWHRGAGTPHAEQLLLSQIPPQTPGVTLYVTLEPCNHWGKT
PPCVDAIINHGIEEVVFSYFDPNPIVAKSNSSEKLREHGIQVRHIPVKAIDVFYKSYAYWTMTHKPRVTVKIAQTFDGKI
GKSEGARVVLSNALCEQFTHQMRAASDVILTSAKTVQMDNPRMNARLDSGLVAKPVAIVDRNLSLSDDTIIFSTAKHCHI
YHQPQANQAKTYPNSTHYAMPLQNGLMDLEAIITHLGQLGYHDVWVEAGGAIFSALHSKGLVHRTYLYLVPGSLGHQAIS
AYQQQGIFEKAHTVSWQAMGDNMIACLDWQEDECLPD

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=329, Percent_Identity=32.5227963525836, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39361; Mature: 39361

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEQFLLAALEQAKLGRGFCAPNPSVGAVAVQNGNIIAQAWHRGAGTPHAEQLLLSQIPP
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEEEHHCCCCCCHHHHHHHHHCCC
QTPGVTLYVTLEPCNHWGKTPPCVDAIINHGIEEVVFSYFDPNPIVAKSNSSEKLREHGI
CCCCEEEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCEEECCCCHHHHHHCCC
QVRHIPVKAIDVFYKSYAYWTMTHKPRVTVKIAQTFDGKIGKSEGARVVLSNALCEQFTH
EEEECCHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHH
QMRAASDVILTSAKTVQMDNPRMNARLDSGLVAKPVAIVDRNLSLSDDTIIFSTAKHCHI
HHHHHHHHEEECCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEECCCEEEE
YHQPQANQAKTYPNSTHYAMPLQNGLMDLEAIITHLGQLGYHDVWVEAGGAIFSALHSKG
EECCCCCCCCCCCCCCEEEEEHHCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCC
LVHRTYLYLVPGSLGHQAISAYQQQGIFEKAHTVSWQAMGDNMIACLDWQEDECLPD
CEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHEEEEEECCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MHEQFLLAALEQAKLGRGFCAPNPSVGAVAVQNGNIIAQAWHRGAGTPHAEQLLLSQIPP
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEEEHHCCCCCCHHHHHHHHHCCC
QTPGVTLYVTLEPCNHWGKTPPCVDAIINHGIEEVVFSYFDPNPIVAKSNSSEKLREHGI
CCCCEEEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCEEECCCCHHHHHHCCC
QVRHIPVKAIDVFYKSYAYWTMTHKPRVTVKIAQTFDGKIGKSEGARVVLSNALCEQFTH
EEEECCHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHH
QMRAASDVILTSAKTVQMDNPRMNARLDSGLVAKPVAIVDRNLSLSDDTIIFSTAKHCHI
HHHHHHHHEEECCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEECCCEEEE
YHQPQANQAKTYPNSTHYAMPLQNGLMDLEAIITHLGQLGYHDVWVEAGGAIFSALHSKG
EECCCCCCCCCCCCCCEEEEEHHCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCC
LVHRTYLYLVPGSLGHQAISAYQQQGIFEKAHTVSWQAMGDNMIACLDWQEDECLPD
CEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHEEEEEECCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]