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The map label for this gene is hbpA

Identifier: 52841194

GI number: 52841194

Start: 1045932

End: 1048115

Strand: Direct

Name: hbpA

Synonym: lpg0959

Alternate gene names: 52841194

Gene position: 1045932-1048115 (Clockwise)

Preceding gene: 52841193

Following gene: 52841195

Centisome position: 30.78

GC content: 37.73

Gene sequence:

>2184_bases
GTGCGGCGATATTTGTTAATTCAATTCATGTTATTTTTAATGCCTTGCTGTGTCAATTTGGCTTATGGCAGTTCTTGGGT
ATTCAATAATCCTTACCCAGAGAGCGAGGCCAATGAAAATATTTATTATTCTTCTTTTAATGAACAGCCAAAAACTCTGG
ATCCGGCACGTTCCTATTCTTCCAATGAATATCTTTTCATAGCCCAGATCTACGAGCCACTGCTGGAATATGATTACTAT
AAAAGACCCTATGAATTAATCCCCTTAACGGCTACCCAGTTACCTAAGATTCGATATTTGGATGCTAATGGAAATCCTGT
TCCGGCAGGAGATAACTCAAAACCGGCATACAGTGTCTATACCATTCAGATAAAAAAAGGAATTTTATATCAACCTCATC
CTGCTTTGGCTCAGAAGAAAGATGGCTCTTATCGATATCATCACTTACCAGAAGATTATTTGGAAGAGCATGATATTGGC
AAGTTATCAGATTTTAAATACACCGGTACAAGGGAGCTGATCATTGATGATTACATTTATCAAATTAAAAGATTGGCAAA
CCCTGCTGTGAGTTCTCCGATATATGGATTGATGAGCTATTATATTCTGGGCTTCAAGGAGTATGGAGATAGTCTTCCTA
AAGGATTGGCCAATAAAAATTCTTTTATTGATTTACGTAAGTATCCTTTGAAGGGGGTTAAAAAATTAGACGATTATACC
TTTGAGATTACATTAAAGGGACAATATACACAATTTTTGTTTTGGTTAGCCATGCCCTTTTTTGCTCCGGTTCCTTGGGA
AGCGGACTTATTTTATTCCCAAAAAGATATGGATGATAAGAACTTATCTTTTGGCTGGTATCCTATAGGTACAGGGCCTT
TTATGCTGACTGAAAATAATCCCAATAGAAGCATGATATTGGAGAAAAATCCTAATTTCAGAGAAGTGTATTTTCCTGTC
AATGGTTCAGATGCCGATAGACGGGCAGGTTATTTAACCAATCTGGGAAGGCGCTTGCCCTTAATTGATAAAGCCGTTTA
TACCCTTGAAAAGGAATCCATACCTCGATGGAATAAATTCTTGCAAGGCTACTATGATATGTCGGGGATAAGTGCTGACA
GTTTTGATCAGGCTATTCATATTAATCGCTTTGGAGAACCTATCCTTAGCCAGGAAATGAAAGATAAAAAAATATATTTA
AGACAAACCCTGGAACCGTCTATCTATTATACTGGCTTTAATATGCTTGACAGCGTTGTTGGGGGCAATAGCAAAAGAGC
ACGAAAATTACGCCAGGCAATTTCTATTGCGGTGAATTTTGATGAAAATATTGCCATATTTTTTAATGGCCGAGGTATTC
CGGCGCAAGGCCCTATTCCACCTGGTATCTTTGGGTACAAGGAAGGAAAAGAGGGTATTAATCCCTATGTTTATCAATGG
GTGAATAATGCGAGGAAACGCAAATCCTTAAAGGACGCGCAGAAGTTAATGGTTGAGGCAGGATATCCGAGAGGGATAGA
TCCGAAAACTGGGAAACACCTGATTCTTCATTATGATGTCATGACGACAGGTGGACCTGATGATAAAGCAAGGCTTGACT
GGATGCGAAAGCAATTTGCAAATATAGGGATAGATTTGAATATTAGGGCGACTCTTTACAATCGTTTCCAGGAAAAGATG
CGGATAGGTCATGCTCAAATATTTAGTTGGGGCTGGAATGCCGATTATCCTGATCCCGAAAATTTTTTATTTTTGCTTTA
TGGGAAAAATGGAAAAGTGAAGTATGGTGGTGAAAATGCATCAAATTATGAAAATCCTGAATTTGATAGATTGTTTAATT
TGATGAAAAATCGCCCTAACGATCTACAAAGACAAAAACTGATTGATAAGATGTTAGCGATTGTCCGGTATGATGCTCCA
TGGGTATGGGGCATGCATTCTGAAGACTTTATTTTATCGCAAGATTGGGTATCTAATATAAAATCCAATACGATTTCTCT
CAATACTCTAAAATATGTTTCTGTTAATGTACCTGAACGTAACCAACTGCGAAGATCCTGGAATCAACCGGTATTTTGGC
CTTTAGGTGTGCTGTTTGGCCTATTGATTGCTCTGGTAATCCCTTTATTGATTACTTATTTAAAGAAAGAAAAACAGCCG
GCAGAAAGAGTAAAATTAAAATGA

Upstream 100 bases:

>100_bases
TAGCTAGATCTTTGTTATTTGGTTTATGATGGGTATCAATGAATCAGGTGAAGTAGGTATTTAAACCTGTAATAATGACT
GATTGGCACGAGGGAAGTAA

Downstream 100 bases:

>100_bases
TTAAATACATACTCCGCAGAATTTTATATGCGATTCCAATTTTGTTTGGTATTAATCTTATTACTTTTGCATTGTTTTTC
ATGGTTAATTCTCCCGATGA

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 727; Mature: 727

Protein sequence:

>727_residues
MRRYLLIQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYY
KRPYELIPLTATQLPKIRYLDANGNPVPAGDNSKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDIG
KLSDFKYTGTRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYT
FEITLKGQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILEKNPNFREVYFPV
NGSDADRRAGYLTNLGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYL
RQTLEPSIYYTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQW
VNNARKRKSLKDAQKLMVEAGYPRGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKM
RIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAP
WVWGMHSEDFILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQP
AERVKLK

Sequences:

>Translated_727_residues
MRRYLLIQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYY
KRPYELIPLTATQLPKIRYLDANGNPVPAGDNSKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDIG
KLSDFKYTGTRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYT
FEITLKGQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILEKNPNFREVYFPV
NGSDADRRAGYLTNLGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYL
RQTLEPSIYYTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQW
VNNARKRKSLKDAQKLMVEAGYPRGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKM
RIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAP
WVWGMHSEDFILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQP
AERVKLK
>Mature_727_residues
MRRYLLIQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYY
KRPYELIPLTATQLPKIRYLDANGNPVPAGDNSKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDIG
KLSDFKYTGTRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYT
FEITLKGQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENNPNRSMILEKNPNFREVYFPV
NGSDADRRAGYLTNLGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYL
RQTLEPSIYYTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQW
VNNARKRKSLKDAQKLMVEAGYPRGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKM
RIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAP
WVWGMHSEDFILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQP
AERVKLK

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=531, Percent_Identity=24.105461393597, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 84456; Mature: 84456

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRYLLIQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCC
SNEYLFIAQIYEPLLEYDYYKRPYELIPLTATQLPKIRYLDANGNPVPAGDNSKPAYSVY
CCCEEEEHHHHHHHHHHHHHCCCCEEEEECHHCCCCEEEECCCCCCCCCCCCCCCCEEEE
TIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDIGKLSDFKYTGTRELIIDDYIY
EEEEECCCEECCCCHHHCCCCCCEEECCCCHHHHHHCCCCCCCCCEECCCHHHHHHHHHH
QIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCHHHHHHCCCEE
FEITLKGQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENN
EEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCC
PNRSMILEKNPNFREVYFPVNGSDADRRAGYLTNLGRRLPLIDKAVYTLEKESIPRWNKF
CCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
LQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIYYTGFNMLDSVV
HHHHHCCCCCCCCCHHCEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHH
GGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQW
CCCHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VNNARKRKSLKDAQKLMVEAGYPRGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHH
NIGIDLNIRATLYNRFQEKMRIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENA
HCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCC
SNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSEDFILSQDWVSNI
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECHHHHHHH
KSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQP
CCCEEEEEEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AERVKLK
HHHCCCC
>Mature Secondary Structure
MRRYLLIQFMLFLMPCCVNLAYGSSWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCC
SNEYLFIAQIYEPLLEYDYYKRPYELIPLTATQLPKIRYLDANGNPVPAGDNSKPAYSVY
CCCEEEEHHHHHHHHHHHHHCCCCEEEEECHHCCCCEEEECCCCCCCCCCCCCCCCEEEE
TIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEEHDIGKLSDFKYTGTRELIIDDYIY
EEEEECCCEECCCCHHHCCCCCCEEECCCCHHHHHHCCCCCCCCCEECCCHHHHHHHHHH
QIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLANKNSFIDLRKYPLKGVKKLDDYT
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCHHHHHHCCCEE
FEITLKGQYTQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFGWYPIGTGPFMLTENN
EEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCC
PNRSMILEKNPNFREVYFPVNGSDADRRAGYLTNLGRRLPLIDKAVYTLEKESIPRWNKF
CCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
LQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIYYTGFNMLDSVV
HHHHHCCCCCCCCCHHCEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHH
GGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQW
CCCHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VNNARKRKSLKDAQKLMVEAGYPRGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHH
NIGIDLNIRATLYNRFQEKMRIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENA
HCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCC
SNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSEDFILSQDWVSNI
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECHHHHHHH
KSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQP
CCCEEEEEEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AERVKLK
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]