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The map label for this gene is era

Identifier: 52841177

GI number: 52841177

Start: 1022940

End: 1023875

Strand: Direct

Name: era

Synonym: lpg0942

Alternate gene names: 52841177

Gene position: 1022940-1023875 (Clockwise)

Preceding gene: 52841173

Following gene: 52841178

Centisome position: 30.11

GC content: 36.75

Gene sequence:

>936_bases
ATGACATGGCTGTTAGAATGTTTTAAAAATAAACAGGAATCAAGATTAATGAGTAGTTATTGTGGTTATATTGCTTTAGT
TGGCAGGCCAAATGTTGGCAAATCAACCTTATTGAATCGTATTTTACAGCAAAAATTAAGTATTACCTCGAGAAAACCAC
AAACCACGCGCCATAGTATTTTAGGAATTCGCACAGAAGGTGAATTTCAGTTTGTTTATGTAGATACTCCTGGTATTCAT
CAGGGTAATGCGAAAGCAATTAATCGCATGATGAATAAAACTGCGATTAGTGTACTACGTGACGTGGATGTGATTGCCTT
TCTAGTTGATGGAACGCATTGGAAAGACGAAGATGAGTATGTGTTGAATTTAATCAAACAAGCTAAAGTTCCTTGCATCC
TGGTAGTTAACAAAGTTGACAAGATAACTGATAAAACACAACTTTTGCCCTGGATAGAGCAAATAAGTCAGCGATATCAA
TTTGCAGCCATTATTCCTTTGTCGGCGAAAACTGGTTTGCAGGTGGATGAGCTGGAAGGCAAATTAAAGAATTATCTGCC
AGAGGGACCTCATTTGTTTCCTGATGATCAATTCACCGATCGGTCTACAAAATTTTTATGTGCCGAATTGCTCCGTGAAA
AAATTTTCCGCTTTTGTGGACAAGAATTGCCTTATTCTGTAACAGTAGATATTGAATCATTTAAGGATGAGGGCAATTTA
ATTCGTATTCATGCCTTGATTTTAGTAGATAAGGATAATCACAAGCGCATGATCATTGGTGATAAAGGCCAAAAATTAAA
AGAAATGGCAACTAATGCCCGTTTGGACATGGAAAAAATGCTAGATAAAAAGGTTTTTTTACAGTGTTGGTGTAAAGTAA
AGTCAGGCTGGTCTGATGATGAGCGAATACTGAAGCAATTGGGATATGACCAGTAA

Upstream 100 bases:

>100_bases
CAAAATCGTTTAATTTAATGCCATTAATGCACAGGGTACTCGAATTGGAACAGAAATAGCAAGCCTATTTAATGAAAAAT
TTGGTATCTCTGGAAGTTTT

Downstream 100 bases:

>100_bases
ATCGCTGAATGCTTGGGTAATTCATAAGCAATGGTCTGGAGATACCAGTGCCAGACTAAAGCTTTTTACTAGGGAACTGG
GATTAATTAATTGCTTGTGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSILGIRTEGEFQFVYVDTPGIH
QGNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEYVLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQ
FAAIIPLSAKTGLQVDELEGKLKNYLPEGPHLFPDDQFTDRSTKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNL
IRIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDDERILKQLGYDQ

Sequences:

>Translated_311_residues
MTWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSILGIRTEGEFQFVYVDTPGIH
QGNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEYVLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQ
FAAIIPLSAKTGLQVDELEGKLKNYLPEGPHLFPDDQFTDRSTKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNL
IRIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDDERILKQLGYDQ
>Mature_310_residues
TWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSILGIRTEGEFQFVYVDTPGIHQ
GNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEYVLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQF
AAIIPLSAKTGLQVDELEGKLKNYLPEGPHLFPDDQFTDRSTKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNLI
RIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDDERILKQLGYDQ

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=308, Percent_Identity=26.2987012987013, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1788919, Length=292, Percent_Identity=53.7671232876712, Blast_Score=344, Evalue=3e-96,
Organism=Escherichia coli, GI87082120, Length=154, Percent_Identity=30.5194805194805, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646434, Length=300, Percent_Identity=27, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35840; Mature: 35709

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSI
CCHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHE
LGIRTEGEFQFVYVDTPGIHQGNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEY
EEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHH
VLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQFAAIIPLSAKTGLQVDELEG
HHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHH
KLKNYLPEGPHLFPDDQFTDRSTKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCE
IRIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDD
EEEEEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
ERILKQLGYDQ
HHHHHHCCCCC
>Mature Secondary Structure 
TWLLECFKNKQESRLMSSYCGYIALVGRPNVGKSTLLNRILQQKLSITSRKPQTTRHSI
CHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHE
LGIRTEGEFQFVYVDTPGIHQGNAKAINRMMNKTAISVLRDVDVIAFLVDGTHWKDEDEY
EEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHH
VLNLIKQAKVPCILVVNKVDKITDKTQLLPWIEQISQRYQFAAIIPLSAKTGLQVDELEG
HHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHH
KLKNYLPEGPHLFPDDQFTDRSTKFLCAELLREKIFRFCGQELPYSVTVDIESFKDEGNL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCE
IRIHALILVDKDNHKRMIIGDKGQKLKEMATNARLDMEKMLDKKVFLQCWCKVKSGWSDD
EEEEEEEEEECCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
ERILKQLGYDQ
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA