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The map label for this gene is 52841060

Identifier: 52841060

GI number: 52841060

Start: 902587

End: 903186

Strand: Reverse

Name: 52841060

Synonym: lpg0824

Alternate gene names: NA

Gene position: 903186-902587 (Counterclockwise)

Preceding gene: 52841061

Following gene: 52841059

Centisome position: 26.58

GC content: 35.33

Gene sequence:

>600_bases
ATGATTAACGAATTAACGACCAGTTTGAATGTGATTGTCACCCAGACACAAAATAACCTGAAAATTTTGGGAGTAATACT
ACTAATTCCCTGGTCAATATTTTTTATTAGTCATTTTATAAGTAATAAAATTTTGCTTCTTGGCATTATCCCAAGGCATA
TATTGGGCCTCCCGGGGATACTATTAGCACCTTTACTTCACGCTAATTTTAATCACTTATTTTTTAACTCTATCCCTTTA
CTGGTTTTAAGTAATTTTATTCTGATTAATGGAGTTAACTATTATTTGATTGTCACAGTGATGATAACTCTTTTTAGCGG
GACACTGATTTGGTGTTTTGCTAAACGAGGTATACACATTGGCGCCAGTGGTTTAATCACAGGCTACTGGGGATTCCTCG
TGTATAACATTTATCAAACAGGTACCTTGACCACTATTATTCTTGGTCTGCTTAGCCTGTATTATTTTGCTGGTATTTTT
CTGGGAATTTTTCCAGGTGAAAAAGGCGTATCCTGGCAAGGCCACTTGTTTGGGCTATTAGCAGGTTTTCTCACCAGCTA
TTTATTAGAAATCTATCCTCAGATTCTCATTTATTATTAG

Upstream 100 bases:

>100_bases
TTGAGCCTTTACTTTTTGTGCCGTTTCGCAAAATCACAGTTACACCAGTTATACCAGATAAAAAATCAAACAAATCAACA
CAAGATGCAACGGCAAAATC

Downstream 100 bases:

>100_bases
TCATTAACTCTTCACAATAGCTAGCCCATGAAACCAATTTATCATTTCACTTTGAACTTTTTTGTCCTAATAAATTCAGT
CTTAAACTGCAATTAAATCA

Product: rhomboid family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MINELTTSLNVIVTQTQNNLKILGVILLIPWSIFFISHFISNKILLLGIIPRHILGLPGILLAPLLHANFNHLFFNSIPL
LVLSNFILINGVNYYLIVTVMITLFSGTLIWCFAKRGIHIGASGLITGYWGFLVYNIYQTGTLTTIILGLLSLYYFAGIF
LGIFPGEKGVSWQGHLFGLLAGFLTSYLLEIYPQILIYY

Sequences:

>Translated_199_residues
MINELTTSLNVIVTQTQNNLKILGVILLIPWSIFFISHFISNKILLLGIIPRHILGLPGILLAPLLHANFNHLFFNSIPL
LVLSNFILINGVNYYLIVTVMITLFSGTLIWCFAKRGIHIGASGLITGYWGFLVYNIYQTGTLTTIILGLLSLYYFAGIF
LGIFPGEKGVSWQGHLFGLLAGFLTSYLLEIYPQILIYY
>Mature_199_residues
MINELTTSLNVIVTQTQNNLKILGVILLIPWSIFFISHFISNKILLLGIIPRHILGLPGILLAPLLHANFNHLFFNSIPL
LVLSNFILINGVNYYLIVTVMITLFSGTLIWCFAKRGIHIGASGLITGYWGFLVYNIYQTGTLTTIILGLLSLYYFAGIF
LGIFPGEKGVSWQGHLFGLLAGFLTSYLLEIYPQILIYY

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 22283; Mature: 22283

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINELTTSLNVIVTQTQNNLKILGVILLIPWSIFFISHFISNKILLLGIIPRHILGLPGI
CCCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHCCCHH
LLAPLLHANFNHLFFNSIPLLVLSNFILINGVNYYLIVTVMITLFSGTLIWCFAKRGIHI
HHHHHHHCCCCHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEHHCCCEE
GASGLITGYWGFLVYNIYQTGTLTTIILGLLSLYYFAGIFLGIFPGEKGVSWQGHLFGLL
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AGFLTSYLLEIYPQILIYY
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINELTTSLNVIVTQTQNNLKILGVILLIPWSIFFISHFISNKILLLGIIPRHILGLPGI
CCCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHCCCHH
LLAPLLHANFNHLFFNSIPLLVLSNFILINGVNYYLIVTVMITLFSGTLIWCFAKRGIHI
HHHHHHHCCCCHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEHHCCCEE
GASGLITGYWGFLVYNIYQTGTLTTIILGLLSLYYFAGIFLGIFPGEKGVSWQGHLFGLL
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AGFLTSYLLEIYPQILIYY
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]