Click here to switch to the map view.

The map label for this gene is ampC

Identifier: 161723243

GI number: 161723243

Start: 2725235

End: 2726314

Strand: Direct

Name: ampC

Synonym: lpg2412

Alternate gene names: 161723243

Gene position: 2725235-2726314 (Clockwise)

Preceding gene: 52842619

Following gene: 52842622

Centisome position: 80.21

GC content: 37.87

Gene sequence:

>1080_bases
ATGAAATCAAAATCCATTAATTTATGCTTTTTTTTATTCATTCTATACTTTGGCAGTCCAATTCTTTTGGCACAACCGTC
CAGGGTGGATAATATAATTAATGAACTGGTTCAACCAATTATTGAGACACATCGGACTCCTGGCTTAGCCATTGCCATTT
ATTATAATGGAAAGGATTATTATTATAATTTTGGATTTGCTGACCGGAAAAGTAAGAAACCCGTCACTAAAAATACTATT
TTTGAATTGGCATCGATTACCAAAATATTCATTAGCACTCTTGTAGCCCTGGAAGTTCAGAAAGGAAAATTGAATGTAAC
AGATTATGCCGTTCAATATACACCTGAACTTTCAAAAACCAATGGACTACCAATTGACAGGGTTCAAATTGTGCATCTGG
CGACCCACACAGCAAGCTTTCCCAAACAAATGGAGCAATTTGGTGTTAATAAAGGCAATATAAAGGCTTTCTTTGCCCGT
CTTAAAACATGGCGTCCTCCAGTAAAAATAGGAACTCAATATAAATATTCCAATATTGGTTTTGGGTATTTGGGATACGT
ATTGGAAAACGCCTCAAACGAAACTTTACCTAATCTGTTAAAATCGAATATTACCAAGCCATTGGGAATGTCGCATACTT
TTTTTAATGTACCAGAAAACCTCGCTAACTATGAAGCTCAAGGTTATCGACCTAAAAATAAGCCAGCACCTTATTATAGA
CCTGCCAATTTTCTAGGCGGAGGTGCTTTGCGCTCTTCTGCAGCTGACATGCTGGTATTTTTAAAAGCAAATTTAGGAGT
TCAACCTGGCACCGCATCACCAGAATTACTTTCTGCGATGCAGTATGCCCAACAACCATTTTTTGAAGTCAACCCAAATT
TTGTTATGGGATTAGGTTGGCAAAGAGTGAAAAGAGGGAGGCACATTGTGATCACTAAAAATGGAGCAAATCAGGGATTT
AGCACCTTTATTGGTTTTTCTCCTGCGAAAAAACTGGGAGTCGTCGTATTAATCAATCAGGCAAGGGGCAAGGCAACCTG
GCTGGGAAACCAAATTCTTAATAGTTTGCTTAGGTTATAG

Upstream 100 bases:

>100_bases
TTGGAGCCCTTACACAATCAGGATAGAATCGCTACAAGATGTCCTGACGATGCAAAATAAAGAAAAAATAATTATTATAT
TTTCCCAAAAGAAATTAATC

Downstream 100 bases:

>100_bases
CTTAAAGGACTATTTTTAAGCATAGACTCATGGGCATTGACAATCAAAATGTCGTGCAACATGATTATCCTTGACCCTAT
TCTCTGTGCGTCTTGACTTA

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKSKSINLCFFLFILYFGSPILLAQPSRVDNIINELVQPIIETHRTPGLAIAIYYNGKDYYYNFGFADRKSKKPVTKNTI
FELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKTNGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIKAFFAR
LKTWRPPVKIGTQYKYSNIGFGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPENLANYEAQGYRPKNKPAPYYR
PANFLGGGALRSSAADMLVFLKANLGVQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGWQRVKRGRHIVITKNGANQGF
STFIGFSPAKKLGVVVLINQARGKATWLGNQILNSLLRL

Sequences:

>Translated_359_residues
MKSKSINLCFFLFILYFGSPILLAQPSRVDNIINELVQPIIETHRTPGLAIAIYYNGKDYYYNFGFADRKSKKPVTKNTI
FELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKTNGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIKAFFAR
LKTWRPPVKIGTQYKYSNIGFGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPENLANYEAQGYRPKNKPAPYYR
PANFLGGGALRSSAADMLVFLKANLGVQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGWQRVKRGRHIVITKNGANQGF
STFIGFSPAKKLGVVVLINQARGKATWLGNQILNSLLRL
>Mature_359_residues
MKSKSINLCFFLFILYFGSPILLAQPSRVDNIINELVQPIIETHRTPGLAIAIYYNGKDYYYNFGFADRKSKKPVTKNTI
FELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKTNGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIKAFFAR
LKTWRPPVKIGTQYKYSNIGFGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPENLANYEAQGYRPKNKPAPYYR
PANFLGGGALRSSAADMLVFLKANLGVQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGWQRVKRGRHIVITKNGANQGF
STFIGFSPAKKLGVVVLINQARGKATWLGNQILNSLLRL

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=391, Percent_Identity=28.3887468030691, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1786574, Length=338, Percent_Identity=22.7810650887574, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 40073; Mature: 40073

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKSINLCFFLFILYFGSPILLAQPSRVDNIINELVQPIIETHRTPGLAIAIYYNGKDY
CCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEE
YYNFGFADRKSKKPVTKNTIFELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEEEEEECCCCCCC
NGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIKAFFARLKTWRPPVKIGTQYKYSNIG
CCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCC
FGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPENLANYEAQGYRPKNKPAPYYR
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEECCCHHHHCCCCCCCCCCCCCCCCCC
PANFLGGGALRSSAADMLVFLKANLGVQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGW
CCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEECCH
QRVKRGRHIVITKNGANQGFSTFIGFSPAKKLGVVVLINQARGKATWLGNQILNSLLRL
HHHHCCCEEEEEECCCCCCCHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSKSINLCFFLFILYFGSPILLAQPSRVDNIINELVQPIIETHRTPGLAIAIYYNGKDY
CCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEE
YYNFGFADRKSKKPVTKNTIFELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEEEEEECCCCCCC
NGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIKAFFARLKTWRPPVKIGTQYKYSNIG
CCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCC
FGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPENLANYEAQGYRPKNKPAPYYR
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEECCCHHHHCCCCCCCCCCCCCCCCCC
PANFLGGGALRSSAADMLVFLKANLGVQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGW
CCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEECCH
QRVKRGRHIVITKNGANQGFSTFIGFSPAKKLGVVVLINQARGKATWLGNQILNSLLRL
HHHHCCCEEEEEECCCCCCCHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9066104 [H]