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The map label for this gene is nuoA-2

Identifier: 39998534

GI number: 39998534

Start: 3791126

End: 3791554

Strand: Reverse

Name: nuoA-2

Synonym: GSU3445

Alternate gene names: 39998534

Gene position: 3791554-3791126 (Counterclockwise)

Preceding gene: 39998535

Following gene: 39998533

Centisome position: 99.41

GC content: 62.7

Gene sequence:

>429_bases
ATGCAACCAGCCGGCATTTCACATTCCCTCTTCCCCTCGTTGCCGCCCGAGTTCCTTCCCCTGGCGCTCTACACCCTTGC
GGCATCCATTCTGATCGGCGTGCTTCTCCTGGCTGCCTGGTGGCTCGGCGCCAAGACCACGAACCGCAACAAGGAACTCC
CCTACGAATCGGGCGCAATCCCCACCGGTTCGGCCCGGCTCGCCTATCCGGTCCCGTTCTACCTCATTGCCATCTTCTTC
ATCGTCTTCGACGTGGAGGCGGCCTTTATCTTCGCCTGGGCCACGGCCTGGCGCGAACTGGGCCTTCAAGGGCTCGTCCA
TATCACCTTCTTCATCGTTATCCTCCTTCTCGGCCTCGTCTGGCTCTGGCTGAAGGGGGGCCTCGACTGGGGACCGTCCC
GTGCACGGAGGGGCCATGTCCGAGACTGA

Upstream 100 bases:

>100_bases
ATGTGGCCGGGCATCGGCGTTTCCCTCAAAACCGTTGACATGAGTCCCGATTGCGCTAGAGTATGAACTCGGCATTTCAC
TCGACGCCAAGGAGAGTAGA

Downstream 100 bases:

>100_bases
GGTCCCACAGAACAACATCATTCTGGCCAGCCTGGACGACCTGATCAACTGGGGCCGGGCCAATTCCCTCTGGCCCATGT
TCTTCGGGCTCTCCTGCTGT

Product: NADH dehydrogenase I subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 2; NDH-1 subunit A 2; NUO1 2

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MQPAGISHSLFPSLPPEFLPLALYTLAASILIGVLLLAAWWLGAKTTNRNKELPYESGAIPTGSARLAYPVPFYLIAIFF
IVFDVEAAFIFAWATAWRELGLQGLVHITFFIVILLLGLVWLWLKGGLDWGPSRARRGHVRD

Sequences:

>Translated_142_residues
MQPAGISHSLFPSLPPEFLPLALYTLAASILIGVLLLAAWWLGAKTTNRNKELPYESGAIPTGSARLAYPVPFYLIAIFF
IVFDVEAAFIFAWATAWRELGLQGLVHITFFIVILLLGLVWLWLKGGLDWGPSRARRGHVRD
>Mature_142_residues
MQPAGISHSLFPSLPPEFLPLALYTLAASILIGVLLLAAWWLGAKTTNRNKELPYESGAIPTGSARLAYPVPFYLIAIFF
IVFDVEAAFIFAWATAWRELGLQGLVHITFFIVILLLGLVWLWLKGGLDWGPSRARRGHVRD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=118, Percent_Identity=45.7627118644068, Blast_Score=110, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA2_GEOSL (Q746S3)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_954485.1
- GeneID:   2688147
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU3445
- NMPDR:   fig|243231.1.peg.3423
- TIGR:   GSU3445
- HOGENOM:   HBG605540
- OMA:   FIEATIF
- ProtClustDB:   CLSK829284
- BioCyc:   GSUL243231:GSU_3445-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 15776; Mature: 15776

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11e1f710)-; HASH(0x12884260)-; HASH(0x12702c84)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPAGISHSLFPSLPPEFLPLALYTLAASILIGVLLLAAWWLGAKTTNRNKELPYESGAI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PTGSARLAYPVPFYLIAIFFIVFDVEAAFIFAWATAWRELGLQGLVHITFFIVILLLGLV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLWLKGGLDWGPSRARRGHVRD
HHHHHCCCCCCCHHHCCCCCCH
>Mature Secondary Structure
MQPAGISHSLFPSLPPEFLPLALYTLAASILIGVLLLAAWWLGAKTTNRNKELPYESGAI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PTGSARLAYPVPFYLIAIFFIVFDVEAAFIFAWATAWRELGLQGLVHITFFIVILLLGLV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLWLKGGLDWGPSRARRGHVRD
HHHHHCCCCCCCHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA