| Definition | Geobacter sulfurreducens PCA chromosome, complete genome. |
|---|---|
| Accession | NC_002939 |
| Length | 3,814,139 |
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The map label for this gene is trxC [H]
Identifier: 39998535
GI number: 39998535
Start: 3791654
End: 3792106
Strand: Reverse
Name: trxC [H]
Synonym: GSU3446
Alternate gene names: 39998535
Gene position: 3792106-3791654 (Counterclockwise)
Preceding gene: 39998536
Following gene: 39998534
Centisome position: 99.42
GC content: 68.65
Gene sequence:
>453_bases ATGGCAGAGAGCGGCCAGTCATTTCTCGTTGCCTGCCCCGCCTGTGGCACGAGCAACCGGGTGCCGGCATCCAGGGAAGG GGTTGCGGGCCGCTGCGGCAGCTGCCGCGGTGTGCTCCCGCCCCTCTATTTCCAGCCGGTCCCGCTTACCGACCGGAGTT TCGACCCGTTCGTCGCTGGCTATCATGGCCCCGTTCTGGTTGAATTCTGGGCCCCCTGGTGACCCCACTGCCGGGACTTC GCACCGGTGGTGCGGGAGGTTGCGCGGGAGCTTGCCGGCACGGCGGCAGTGGTTCAGGTGAACACCCAGGAGAACCCGCA GCTGGCAGCCCGCTTCGGCATCCGGGGGATTCCGGCCCTGGTGCTCCTGCGACGGGGGCAGGTGCTCGCAACCTGGAGCG GTGCACTACCCAGAGAGGCGGTGCTTTCCCGGGTCCGCGATGCCCTGCGCTAA
Upstream 100 bases:
>100_bases CGACGGGACGGTGGTGAAGCACTGGTCCAAGGTGGCCAAGGCAGAGGCCCATCCGGCGCAGGTGGCGGAGTTCCTCGCCA AGCAGGGGTAGGAACCTCCC
Downstream 100 bases:
>100_bases TGTGGCCGGGCATCGGCGTTTCCCTCAAAACCGTTGACATGAGTCCCGATTGCGCTAGAGTATGAACTCGGCATTTCACT CGACGCCAAGGAGAGTAGAA
Product: thioredoxin
Products: NA
Alternate protein names: Trx-2; Protein-disulfide reductase [H]
Number of amino acids: Translated: 150; Mature: 149
Protein sequence:
>150_residues MAESGQSFLVACPACGTSNRVPASREGVAGRCGSCRGVLPPLYFQPVPLTDRSFDPFVAGYHGPVLVEFWAPWUPHCRDF APVVREVARELAGTAAVVQVNTQENPQLAARFGIRGIPALVLLRRGQVLATWSGALPREAVLSRVRDALR
Sequences:
>Translated_150_residues MAESGQSFLVACPACGTSNRVPASREGVAGRCGSCRGVLPPLYFQPVPLTDRSFDPFVAGYHGPVLVEFWAPW*PHCRDF APVVREVARELAGTAAVVQVNTQENPQLAARFGIRGIPALVLLRRGQVLATWSGALPREAVLSRVRDALR >Mature_149_residues AESGQSFLVACPACGTSNRVPASREGVAGRCGSCRGVLPPLYFQPVPLTDRSFDPFVAGYHGPVLVEFWAPW*PHCRDFA PVVREVARELAGTAAVVQVNTQENPQLAARFGIRGIPALVLLRRGQVLATWSGALPREAVLSRVRDALR
Specific function: Efficient electron donor for the essential enzyme ribonucleotide reductase. Is also able to reduce the interchain disulfide bridges of insulin [H]
COG id: COG0526
COG function: function code OC; Thiol-disulfide isomerase and thioredoxins
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 thioredoxin domain [H]
Homologues:
Organism=Homo sapiens, GI5031973, Length=105, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=3e-12, Organism=Escherichia coli, GI1788936, Length=138, Percent_Identity=35.5072463768116, Blast_Score=94, Evalue=3e-21, Organism=Escherichia coli, GI87082331, Length=92, Percent_Identity=44.5652173913043, Blast_Score=87, Evalue=6e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005746 - InterPro: IPR017936 - InterPro: IPR012336 - InterPro: IPR017937 - InterPro: IPR013766 - InterPro: IPR012335 [H]
Pfam domain/function: PF00085 Thioredoxin [H]
EC number: =1.8.1.8 [H]
Molecular weight: Translated: 16060; Mature: 15928
Theoretical pI: Translated: 9.12; Mature: 9.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
3.3 %Cys (Translated Protein) 0.7 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 3.4 %Cys (Mature Protein) 0.0 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAESGQSFLVACPACGTSNRVPASREGVAGRCGSCRGVLPPLYFQPVPLTDRSFDPFVAG CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEC YHGPVLVEFWAPWPHCRDFAPVVREVARELAGTAAVVQVNTQENPQLAARFGIRGIPALV CCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCHHHH LLRRGQVLATWSGALPREAVLSRVRDALR HHHCCCEEEEECCCCCHHHHHHHHHHHHC >Mature Secondary Structure AESGQSFLVACPACGTSNRVPASREGVAGRCGSCRGVLPPLYFQPVPLTDRSFDPFVAG CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEC YHGPVLVEFWAPWPHCRDFAPVVREVARELAGTAAVVQVNTQENPQLAARFGIRGIPALV CCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCHHHH LLRRGQVLATWSGALPREAVLSRVRDALR HHHCCCEEEEECCCCCHHHHHHHHHHHHC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]