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The map label for this gene is nuoH-2 [H]

Identifier: 39998525

GI number: 39998525

Start: 3780842

End: 3781831

Strand: Reverse

Name: nuoH-2 [H]

Synonym: GSU3436

Alternate gene names: 39998525

Gene position: 3781831-3780842 (Counterclockwise)

Preceding gene: 39998526

Following gene: 39998524

Centisome position: 99.15

GC content: 63.54

Gene sequence:

>990_bases
ATGAACGGAGTTGCTCTCGACATAGCCATCCACGGGGCCAAGATCGCCCTGATCTTCTTCGTGGTGCTCACCCTGGCGGC
CTACCTGGTCTTCGCCGAGCGGCGGCTCCTGGCCTGGATCCAGGACCGCAAGGGGCCGAACCGGGTGGGCCCCTTCGGCC
TGCTGCAGCCCCTGGCGGATCTCATCAAACTCCTGACCAAGGAGGATTTCCGCCCCGCCGGCGCCGACAAGTGGCTCTTC
TATCTGGCCCCGGCCATGGCTGCCGTCCCGGCGATCCTCACCTTTGCGGTGATCCCCTTCGGGGCGCCGGTCACGATTCT
CGGCCGTGAGATCCCGCTTCAGGTGGCGGATCTGAACGTGGGGCTCCTCTTCTTCTTGGCACTCTCCTCCATTGCGGTGT
ATGGTGTGGCCCTGGGGGGATGGGCGTCCAACTCCAAGTACGCGCTCCTGGGCTCCATCCGGGGGCTGGCCCAGCTCATC
TCCTACGAGCTCTCCATGGGGCTGTCCCTGGTGCCCACGGTGATGCTGGCCGGGTCGCTCCGGCTGTCGGACATCGTGGC
GGCCCAGGAGGGGGTCTGGTTCATCGCCTACCAGCCCGTGGCCTTTCTGATCTTTCTCATCAGCATCGCGGCCGAATGCA
AGCGGATACCCTTTGACATCCCCGAGGCGGAGGGAGAGCTGGTGGCGGGGTTCCACACCGAGTACTCGGGGATGCGTTTC
GGCCTCTTTTTCGTGGGCGAGTACATCAACATCATCGTCCTCGGCGGTTTGGCAACCACCTTCTTTCTGGGCGGCTGGCA
GGGGCCGCTGCTGCCTCCCTTCGTCTGGTTTTCGGTGAAGACTCTCGCCTTCGCCTTCTTTTTCATCTGGATGCGGGGAA
CCCTGCCGCGGTTGCGCTACGATCAGCTCATGCACCTGGGATGGAAGGTGCTGACGCCGCTGGCACTGCTCAACATCCTG
ATCACCGGATGGGTACTGATGTTCGTGTAA

Upstream 100 bases:

>100_bases
AGCGGATCATCGACCGCCATGGAGGGCGCATCTGGGCGGAGGGAACGCCCGGCGCCGGCGCCACGTTTTACTTCACGTTG
CCGGAACCCGGCGGGGAGTC

Downstream 100 bases:

>100_bases
CGGAGAGACAAACACCATCGAGAGAAAGGGGGGAGAGAACGTTCGCACCACGCACAACCGCATCACGGTCTGACACACGC
ACACTGGTCATCGTTCCGCA

Product: NADH dehydrogenase I subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H 1; NDH-1 subunit H 1 [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNGVALDIAIHGAKIALIFFVVLTLAAYLVFAERRLLAWIQDRKGPNRVGPFGLLQPLADLIKLLTKEDFRPAGADKWLF
YLAPAMAAVPAILTFAVIPFGAPVTILGREIPLQVADLNVGLLFFLALSSIAVYGVALGGWASNSKYALLGSIRGLAQLI
SYELSMGLSLVPTVMLAGSLRLSDIVAAQEGVWFIAYQPVAFLIFLISIAAECKRIPFDIPEAEGELVAGFHTEYSGMRF
GLFFVGEYINIIVLGGLATTFFLGGWQGPLLPPFVWFSVKTLAFAFFFIWMRGTLPRLRYDQLMHLGWKVLTPLALLNIL
ITGWVLMFV

Sequences:

>Translated_329_residues
MNGVALDIAIHGAKIALIFFVVLTLAAYLVFAERRLLAWIQDRKGPNRVGPFGLLQPLADLIKLLTKEDFRPAGADKWLF
YLAPAMAAVPAILTFAVIPFGAPVTILGREIPLQVADLNVGLLFFLALSSIAVYGVALGGWASNSKYALLGSIRGLAQLI
SYELSMGLSLVPTVMLAGSLRLSDIVAAQEGVWFIAYQPVAFLIFLISIAAECKRIPFDIPEAEGELVAGFHTEYSGMRF
GLFFVGEYINIIVLGGLATTFFLGGWQGPLLPPFVWFSVKTLAFAFFFIWMRGTLPRLRYDQLMHLGWKVLTPLALLNIL
ITGWVLMFV
>Mature_329_residues
MNGVALDIAIHGAKIALIFFVVLTLAAYLVFAERRLLAWIQDRKGPNRVGPFGLLQPLADLIKLLTKEDFRPAGADKWLF
YLAPAMAAVPAILTFAVIPFGAPVTILGREIPLQVADLNVGLLFFLALSSIAVYGVALGGWASNSKYALLGSIRGLAQLI
SYELSMGLSLVPTVMLAGSLRLSDIVAAQEGVWFIAYQPVAFLIFLISIAAECKRIPFDIPEAEGELVAGFHTEYSGMRF
GLFFVGEYINIIVLGGLATTFFLGGWQGPLLPPFVWFSVKTLAFAFFFIWMRGTLPRLRYDQLMHLGWKVLTPLALLNIL
ITGWVLMFV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=292, Percent_Identity=44.8630136986301, Blast_Score=244, Evalue=7e-65,
Organism=Escherichia coli, GI1788618, Length=314, Percent_Identity=50.6369426751592, Blast_Score=310, Evalue=6e-86,
Organism=Escherichia coli, GI1789077, Length=312, Percent_Identity=30.1282051282051, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 36088; Mature: 36088

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGVALDIAIHGAKIALIFFVVLTLAAYLVFAERRLLAWIQDRKGPNRVGPFGLLQPLAD
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LIKLLTKEDFRPAGADKWLFYLAPAMAAVPAILTFAVIPFGAPVTILGREIPLQVADLNV
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCH
GLLFFLALSSIAVYGVALGGWASNSKYALLGSIRGLAQLISYELSMGLSLVPTVMLAGSL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
RLSDIVAAQEGVWFIAYQPVAFLIFLISIAAECKRIPFDIPEAEGELVAGFHTEYSGMRF
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEE
GLFFVGEYINIIVLGGLATTFFLGGWQGPLLPPFVWFSVKTLAFAFFFIWMRGTLPRLRY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DQLMHLGWKVLTPLALLNILITGWVLMFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNGVALDIAIHGAKIALIFFVVLTLAAYLVFAERRLLAWIQDRKGPNRVGPFGLLQPLAD
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LIKLLTKEDFRPAGADKWLFYLAPAMAAVPAILTFAVIPFGAPVTILGREIPLQVADLNV
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCH
GLLFFLALSSIAVYGVALGGWASNSKYALLGSIRGLAQLISYELSMGLSLVPTVMLAGSL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
RLSDIVAAQEGVWFIAYQPVAFLIFLISIAAECKRIPFDIPEAEGELVAGFHTEYSGMRF
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEE
GLFFVGEYINIIVLGGLATTFFLGGWQGPLLPPFVWFSVKTLAFAFFFIWMRGTLPRLRY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DQLMHLGWKVLTPLALLNILITGWVLMFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA