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The map label for this gene is nudL [H]

Identifier: 39998464

GI number: 39998464

Start: 3709465

End: 3709980

Strand: Direct

Name: nudL [H]

Synonym: GSU3375

Alternate gene names: 39998464

Gene position: 3709465-3709980 (Clockwise)

Preceding gene: 39998463

Following gene: 39998465

Centisome position: 97.26

GC content: 62.21

Gene sequence:

>516_bases
GTGCCGATGGCGCCGGGACCGATCCCGGCCGCGGTGTTGCTCCCCCTCTTCGAGCGGGACGGCGAAGTCCACGTTCTTTT
CACCAAGCGGACGGAACACCTGAACCATCATCGGGGAGAAATCTCGTTTCCCGGCGGAGTGAGCCATCCCGATGATGCCT
CTCCCTGTGAAACAGCCCTGCGGGAAACTTGGGAAGAGATAGGCATTCCGCCCGGCGAGGTGGACATCCTCGGCGAGCTG
GATGATTTTTATTCCGTCCACGACTACCTGGTGACCCCCTGCGTGGGAGTCATCCGGGGGGACCGCCCGCTGGTGGTGAA
CCCCGGCGAGATCGAACGGATCATTGTCGTGCCGCTGAAGCATCTGCTGCGGCCCGAGGCCTTCAGGACCGAAGATTGGA
CGTGGCGCGGACGGACGCACCCCGTTCACTTCTACCGGTACATGGATGACGAAATATGGGGGCTCACGGCCGCCATACTC
TCGCAGTTCCTCAACACGATATTCCCTCGGCCGTGA

Upstream 100 bases:

>100_bases
TTGGCCGCTATTTGGCTTTCTGGAAACAACAGGAATGGATGTACCGGGAATAACCGAACTTGCCGGACGGATTTGTACGA
CCCTGGCCGGGCGGACAAGG

Downstream 100 bases:

>100_bases
CCGGGGCGGGACGTTCCCACGGATTACCCATCCGCGCGGAGAAGCATGAAACCATGGCGATGACAGCCCTCGTAATCGAC
GATTCGGAAGTCCTGCGCGA

Product: mutT/nudix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPMAPGPIPAAVLLPLFERDGEVHVLFTKRTEHLNHHRGEISFPGGVSHPDDASPCETALRETWEEIGIPPGEVDILGEL
DDFYSVHDYLVTPCVGVIRGDRPLVVNPGEIERIIVVPLKHLLRPEAFRTEDWTWRGRTHPVHFYRYMDDEIWGLTAAIL
SQFLNTIFPRP

Sequences:

>Translated_171_residues
MPMAPGPIPAAVLLPLFERDGEVHVLFTKRTEHLNHHRGEISFPGGVSHPDDASPCETALRETWEEIGIPPGEVDILGEL
DDFYSVHDYLVTPCVGVIRGDRPLVVNPGEIERIIVVPLKHLLRPEAFRTEDWTWRGRTHPVHFYRYMDDEIWGLTAAIL
SQFLNTIFPRP
>Mature_170_residues
PMAPGPIPAAVLLPLFERDGEVHVLFTKRTEHLNHHRGEISFPGGVSHPDDASPCETALRETWEEIGIPPGEVDILGELD
DFYSVHDYLVTPCVGVIRGDRPLVVNPGEIERIIVVPLKHLLRPEAFRTEDWTWRGRTHPVHFYRYMDDEIWGLTAAILS
QFLNTIFPRP

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=162, Percent_Identity=36.4197530864198, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788115, Length=162, Percent_Identity=37.037037037037, Blast_Score=84, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17536993, Length=176, Percent_Identity=36.3636363636364, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI18859683, Length=166, Percent_Identity=34.9397590361446, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 19448; Mature: 19317

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMAPGPIPAAVLLPLFERDGEVHVLFTKRTEHLNHHRGEISFPGGVSHPDDASPCETAL
CCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCEECCCCCCCCCCCCHHHHHH
RETWEEIGIPPGEVDILGELDDFYSVHDYLVTPCVGVIRGDRPLVVNPGEIERIIVVPLK
HHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEHH
HLLRPEAFRTEDWTWRGRTHPVHFYRYMDDEIWGLTAAILSQFLNTIFPRP
HHHCCCCCCCCCCEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PMAPGPIPAAVLLPLFERDGEVHVLFTKRTEHLNHHRGEISFPGGVSHPDDASPCETAL
CCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCEECCCCCCCCCCCCHHHHHH
RETWEEIGIPPGEVDILGELDDFYSVHDYLVTPCVGVIRGDRPLVVNPGEIERIIVVPLK
HHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEHH
HLLRPEAFRTEDWTWRGRTHPVHFYRYMDDEIWGLTAAILSQFLNTIFPRP
HHHCCCCCCCCCCEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]