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The map label for this gene is rpe [H]

Identifier: 39998463

GI number: 39998463

Start: 3708688

End: 3709353

Strand: Direct

Name: rpe [H]

Synonym: GSU3374

Alternate gene names: 39998463

Gene position: 3708688-3709353 (Clockwise)

Preceding gene: 39998462

Following gene: 39998464

Centisome position: 97.24

GC content: 61.26

Gene sequence:

>666_bases
ATGAAAAAAATTGCCCCATCAATCCTTTCCGCCGACTTTTCCCGCCTGGGCGATGAAGTCCGTGCCGTGGCGGCGGCCGG
GGCTGATTATATCCACGTGGACGTCATGGACGGGCACTTCGTGCCCAACATAACCATCGGCCCCCTGGTGGTGGAGGCGG
TGCGCAGGGTTACCGAGCTTCCCCTGGACGTCCACCTGATGATCGAGCATCCCGACCGCTACATCCCCGACTTCGCCGCC
GCAGGTTCGGATATCATCGTGGTCCACGCGGAGGCTTCCACTCACCTCCACCGTACGATCCAGCTCATCAAGTCCCTGGG
CAAGAAGGCGGGGGTTTCCCTCAATCCGGCCACTCCCCTCAACTGCCTCGACTATGTCCTCGAGGATCTCGACCTGGTGC
TGCTCATGACCGTCAACCCGGGATTCGGAGGCCAATCGTTCATCGAGGCCTGCATTCCCAAGATCCAGTCACTGCGGGCA
ATGCTCGACCGCCGCGGCTGCGAGGCGGAGCTTGAGGTGGACGGCGGGGTGAAGATCGACAACATCGCCCGCATCGCCCA
TGCCGGCGCCGACGTCTTCGTGGCCGGAAGCGCCATTTTCGGCAGCCCCGACTATGAAGCAACCATAAAAGAGCTAAAGC
GTCGGGCAAAAGAGCCGATACTGTAA

Upstream 100 bases:

>100_bases
TCCGCAGCTGGCCCCACCGCCACGGCATGGACGGTTTTTTCGCCGCCCGCCTGCGTCGGGCCTGAGGCGACAACGCTTAG
AGCAGATCCCGGAGGTTCCC

Downstream 100 bases:

>100_bases
CTACGCGGCCGTTGGCCGCTATTTGGCTTTCTGGAAACAACAGGAATGGATGTACCGGGAATAACCGAACTTGCCGGACG
GATTTGTACGACCCTGGCCG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPLVVEAVRRVTELPLDVHLMIEHPDRYIPDFAA
AGSDIIVVHAEASTHLHRTIQLIKSLGKKAGVSLNPATPLNCLDYVLEDLDLVLLMTVNPGFGGQSFIEACIPKIQSLRA
MLDRRGCEAELEVDGGVKIDNIARIAHAGADVFVAGSAIFGSPDYEATIKELKRRAKEPIL

Sequences:

>Translated_221_residues
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPLVVEAVRRVTELPLDVHLMIEHPDRYIPDFAA
AGSDIIVVHAEASTHLHRTIQLIKSLGKKAGVSLNPATPLNCLDYVLEDLDLVLLMTVNPGFGGQSFIEACIPKIQSLRA
MLDRRGCEAELEVDGGVKIDNIARIAHAGADVFVAGSAIFGSPDYEATIKELKRRAKEPIL
>Mature_221_residues
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPLVVEAVRRVTELPLDVHLMIEHPDRYIPDFAA
AGSDIIVVHAEASTHLHRTIQLIKSLGKKAGVSLNPATPLNCLDYVLEDLDLVLLMTVNPGFGGQSFIEACIPKIQSLRA
MLDRRGCEAELEVDGGVKIDNIARIAHAGADVFVAGSAIFGSPDYEATIKELKRRAKEPIL

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=218, Percent_Identity=40.8256880733945, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI219879828, Length=218, Percent_Identity=38.9908256880734, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI24307923, Length=173, Percent_Identity=31.7919075144509, Blast_Score=95, Evalue=4e-20,
Organism=Escherichia coli, GI1789788, Length=211, Percent_Identity=58.7677725118483, Blast_Score=257, Evalue=5e-70,
Organism=Escherichia coli, GI1790523, Length=197, Percent_Identity=39.5939086294416, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1790754, Length=207, Percent_Identity=36.231884057971, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17552948, Length=222, Percent_Identity=37.3873873873874, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6322341, Length=233, Percent_Identity=41.2017167381974, Blast_Score=180, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24586301, Length=212, Percent_Identity=39.622641509434, Blast_Score=159, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23837; Mature: 23837

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPLVVEAVRRVTEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHC
PLDVHLMIEHPDRYIPDFAAAGSDIIVVHAEASTHLHRTIQLIKSLGKKAGVSLNPATPL
CCEEEEEEECCCCCCCHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
NCLDYVLEDLDLVLLMTVNPGFGGQSFIEACIPKIQSLRAMLDRRGCEAELEVDGGVKID
HHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEHH
NIARIAHAGADVFVAGSAIFGSPDYEATIKELKRRAKEPIL
HHHHHHHCCCCEEEECCEEECCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKIAPSILSADFSRLGDEVRAVAAAGADYIHVDVMDGHFVPNITIGPLVVEAVRRVTEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHC
PLDVHLMIEHPDRYIPDFAAAGSDIIVVHAEASTHLHRTIQLIKSLGKKAGVSLNPATPL
CCEEEEEEECCCCCCCHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
NCLDYVLEDLDLVLLMTVNPGFGGQSFIEACIPKIQSLRAMLDRRGCEAELEVDGGVKID
HHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEHH
NIARIAHAGADVFVAGSAIFGSPDYEATIKELKRRAKEPIL
HHHHHHHCCCCEEEECCEEECCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]