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The map label for this gene is sun [H]

Identifier: 39998462

GI number: 39998462

Start: 3707306

End: 3708652

Strand: Direct

Name: sun [H]

Synonym: GSU3373

Alternate gene names: 39998462

Gene position: 3707306-3708652 (Clockwise)

Preceding gene: 39998460

Following gene: 39998463

Centisome position: 97.2

GC content: 64.88

Gene sequence:

>1347_bases
GTGAACCAATCCACTGCCGACCCGCGCCGTTCGGCTTTTGATATCCTCGTCCGCATTGAACGGGAGCGAACCTTCGCCGA
ACCGCTCATCGACAGGGAATTGTCCGGTGGCGCCCTGAAGGGACCAGACCGGGGGCTCCTGACCGAGCTCGTCTATGGGG
TGCTGCGTCGAACAGCGACCCTCGACTACCTGGTGGACCTGTTCTGCGCCACTCGCGCCGCCAAGCTGGAGCGATCAGTG
CTGATCCTGCTCCGTCTGGGGCTTTACCAGATTTTCTTCCTTGACCGGATTCCGGTGTCCGCCGCAGTCAACGAAACGGT
AACGCTGGCCCGTGAAAAATCACCACGGGCCAGCGGCCTCGTAAACGCAGTCCTGCGACGGTCCGACCGGGAACGGTCAT
CGATCGCCTGGCCTGACCGGGTGCGGGACCCGGCCGGCTACCTCGCCCTCCGTCACTCCCATCCCCGCTGGATCGTGGAA
GGGTGGATCGCCCAGCTGGGGTTCGAAGAGGCGGAGGCGCTTGCCGAGGTCATGGCCGCGCCCCCTCCCCTGACCCTCCG
GGTCAATACCCTGCGGACCTCCCGCGAGGCATACCTTGAACTCCTGCGGGAGGCAGGCACGGAAGCGGAGCCCACGCGCC
ATTCCCCCCACGGCATCCGTATTCTCTCACGGACAGCGGTGCCGGCGCTGCCGGGCTTTGGCGAGGGGCTCGTCATCGTG
CAGGACGAATCCTCTCAACTGGCATCGCTCCTCCTGGAGCCCCGGAGCGGTGAACGGGTCCTCGATGCCTGCGCTTCCCC
CGGCGGCAAGGCGACCCACCTTGCCCAGATCATGGCCGACAAGGGAGAGGTCATTGCCTGGGACGTGTCGGAGAAAAAGC
TCTCTCCGATTGCTGAAAATGCCCGCCGTCTGGGCATCGGCATCATTCGGCCCGCCATGGCCGATGCCCGGAATCCGGAG
CAGAACGCCGCTCCCTTCGACAGGATTCTGGTGGACGCCCCCTGCTCGGCACTGGGAGTGCTGCGCCGCACCCCTGAGGG
GAAGTGGTGGAAGACCCCTGACGACGTGGCACGGCTGGCCCAGAGCCAGTGCCGGATACTGGCGGGGGCCGCCTCCCTGC
TGAAGCCGGGCGGCACGCTCCTCTACTCCACCTGCTCCACCACAACGGACGAAAATGAGTCAATTATCGAGGATTTCCTT
TCGCGCCGCGCCGATTTTATGTTAGAAGACTTGAATTATCTTTTCCCCGGCCTGTCAGAATGCATCACCGACCGGGGTAT
GTTCCGCAGCTGGCCCCACCGCCACGGCATGGACGGTTTTTTCGCCGCCCGCCTGCGTCGGGCCTGA

Upstream 100 bases:

>100_bases
GGTTTCCTTGCGGATGGGTTGCCGGCTGGACTATAATGAATCCTCACCCGCGCTTCGCAGCACACCGGCGCGAAATCCAG
CTTGGACTCCGGGAGCATCC

Downstream 100 bases:

>100_bases
GGCGACAACGCTTAGAGCAGATCCCGGAGGTTCCCATGAAAAAAATTGCCCCATCAATCCTTTCCGCCGACTTTTCCCGC
CTGGGCGATGAAGTCCGTGC

Product: Sun protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MNQSTADPRRSAFDILVRIERERTFAEPLIDRELSGGALKGPDRGLLTELVYGVLRRTATLDYLVDLFCATRAAKLERSV
LILLRLGLYQIFFLDRIPVSAAVNETVTLAREKSPRASGLVNAVLRRSDRERSSIAWPDRVRDPAGYLALRHSHPRWIVE
GWIAQLGFEEAEALAEVMAAPPPLTLRVNTLRTSREAYLELLREAGTEAEPTRHSPHGIRILSRTAVPALPGFGEGLVIV
QDESSQLASLLLEPRSGERVLDACASPGGKATHLAQIMADKGEVIAWDVSEKKLSPIAENARRLGIGIIRPAMADARNPE
QNAAPFDRILVDAPCSALGVLRRTPEGKWWKTPDDVARLAQSQCRILAGAASLLKPGGTLLYSTCSTTTDENESIIEDFL
SRRADFMLEDLNYLFPGLSECITDRGMFRSWPHRHGMDGFFAARLRRA

Sequences:

>Translated_448_residues
MNQSTADPRRSAFDILVRIERERTFAEPLIDRELSGGALKGPDRGLLTELVYGVLRRTATLDYLVDLFCATRAAKLERSV
LILLRLGLYQIFFLDRIPVSAAVNETVTLAREKSPRASGLVNAVLRRSDRERSSIAWPDRVRDPAGYLALRHSHPRWIVE
GWIAQLGFEEAEALAEVMAAPPPLTLRVNTLRTSREAYLELLREAGTEAEPTRHSPHGIRILSRTAVPALPGFGEGLVIV
QDESSQLASLLLEPRSGERVLDACASPGGKATHLAQIMADKGEVIAWDVSEKKLSPIAENARRLGIGIIRPAMADARNPE
QNAAPFDRILVDAPCSALGVLRRTPEGKWWKTPDDVARLAQSQCRILAGAASLLKPGGTLLYSTCSTTTDENESIIEDFL
SRRADFMLEDLNYLFPGLSECITDRGMFRSWPHRHGMDGFFAARLRRA
>Mature_448_residues
MNQSTADPRRSAFDILVRIERERTFAEPLIDRELSGGALKGPDRGLLTELVYGVLRRTATLDYLVDLFCATRAAKLERSV
LILLRLGLYQIFFLDRIPVSAAVNETVTLAREKSPRASGLVNAVLRRSDRERSSIAWPDRVRDPAGYLALRHSHPRWIVE
GWIAQLGFEEAEALAEVMAAPPPLTLRVNTLRTSREAYLELLREAGTEAEPTRHSPHGIRILSRTAVPALPGFGEGLVIV
QDESSQLASLLLEPRSGERVLDACASPGGKATHLAQIMADKGEVIAWDVSEKKLSPIAENARRLGIGIIRPAMADARNPE
QNAAPFDRILVDAPCSALGVLRRTPEGKWWKTPDDVARLAQSQCRILAGAASLLKPGGTLLYSTCSTTTDENESIIEDFL
SRRADFMLEDLNYLFPGLSECITDRGMFRSWPHRHGMDGFFAARLRRA

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=320, Percent_Identity=32.1875, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI76150623, Length=320, Percent_Identity=32.1875, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI32698918, Length=169, Percent_Identity=40.2366863905325, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI8922322, Length=315, Percent_Identity=29.5238095238095, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI270288818, Length=315, Percent_Identity=29.5238095238095, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI270288816, Length=315, Percent_Identity=29.5238095238095, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI23199998, Length=315, Percent_Identity=29.5238095238095, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI301336155, Length=263, Percent_Identity=30.0380228136882, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI39995082, Length=201, Percent_Identity=32.8358208955224, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI11545785, Length=185, Percent_Identity=31.8918918918919, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI2367212, Length=406, Percent_Identity=38.423645320197, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI87081985, Length=280, Percent_Identity=33.2142857142857, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17536757, Length=292, Percent_Identity=31.1643835616438, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71998419, Length=222, Percent_Identity=28.8288288288288, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI115534021, Length=222, Percent_Identity=28.8288288288288, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=224, Percent_Identity=33.9285714285714, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324268, Length=297, Percent_Identity=32.3232323232323, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319447, Length=318, Percent_Identity=26.1006289308176, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI22024126, Length=313, Percent_Identity=31.3099041533546, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24668781, Length=258, Percent_Identity=29.8449612403101, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356513, Length=258, Percent_Identity=29.8449612403101, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356579, Length=171, Percent_Identity=30.9941520467836, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920494, Length=213, Percent_Identity=30.9859154929577, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21355201, Length=242, Percent_Identity=30.5785123966942, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: 2.1.1.-

Molecular weight: Translated: 49575; Mature: 49575

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSTADPRRSAFDILVRIERERTFAEPLIDRELSGGALKGPDRGLLTELVYGVLRRTAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LDYLVDLFCATRAAKLERSVLILLRLGLYQIFFLDRIPVSAAVNETVTLAREKSPRASGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHH
VNAVLRRSDRERSSIAWPDRVRDPAGYLALRHSHPRWIVEGWIAQLGFEEAEALAEVMAA
HHHHHHHCCCCCCCCCCCHHHCCCCHHEEEECCCCHHHHHHHHHHHCHHHHHHHHHHHHC
PPPLTLRVNTLRTSREAYLELLREAGTEAEPTRHSPHGIRILSRTAVPALPGFGEGLVIV
CCCCEEEEHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHCCCCCCCCCCCEEEE
QDESSQLASLLLEPRSGERVLDACASPGGKATHLAQIMADKGEVIAWDVSEKKLSPIAEN
ECCHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCHHHCCHHHHH
ARRLGIGIIRPAMADARNPEQNAAPFDRILVDAPCSALGVLRRTPEGKWWKTPDDVARLA
HHHHCHHHHHHHHHCCCCCCCCCCCHHHHEECCCHHHHHHHHCCCCCCCCCCHHHHHHHH
QSQCRILAGAASLLKPGGTLLYSTCSTTTDENESIIEDFLSRRADFMLEDLNYLFPGLSE
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
CITDRGMFRSWPHRHGMDGFFAARLRRA
HHHCCCHHHCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNQSTADPRRSAFDILVRIERERTFAEPLIDRELSGGALKGPDRGLLTELVYGVLRRTAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LDYLVDLFCATRAAKLERSVLILLRLGLYQIFFLDRIPVSAAVNETVTLAREKSPRASGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHH
VNAVLRRSDRERSSIAWPDRVRDPAGYLALRHSHPRWIVEGWIAQLGFEEAEALAEVMAA
HHHHHHHCCCCCCCCCCCHHHCCCCHHEEEECCCCHHHHHHHHHHHCHHHHHHHHHHHHC
PPPLTLRVNTLRTSREAYLELLREAGTEAEPTRHSPHGIRILSRTAVPALPGFGEGLVIV
CCCCEEEEHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHCCCCCCCCCCCEEEE
QDESSQLASLLLEPRSGERVLDACASPGGKATHLAQIMADKGEVIAWDVSEKKLSPIAEN
ECCHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCHHHCCHHHHH
ARRLGIGIIRPAMADARNPEQNAAPFDRILVDAPCSALGVLRRTPEGKWWKTPDDVARLA
HHHHCHHHHHHHHHCCCCCCCCCCCHHHHEECCCHHHHHHHHCCCCCCCCCCHHHHHHHH
QSQCRILAGAASLLKPGGTLLYSTCSTTTDENESIIEDFLSRRADFMLEDLNYLFPGLSE
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
CITDRGMFRSWPHRHGMDGFFAARLRRA
HHHCCCHHHCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]