| Definition | Geobacter sulfurreducens PCA chromosome, complete genome. |
|---|---|
| Accession | NC_002939 |
| Length | 3,814,139 |
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The map label for this gene is cls [H]
Identifier: 39998461
GI number: 39998461
Start: 3705606
End: 3707048
Strand: Reverse
Name: cls [H]
Synonym: GSU3372
Alternate gene names: 39998461
Gene position: 3707048-3705606 (Counterclockwise)
Preceding gene: 39998466
Following gene: 39998459
Centisome position: 97.19
GC content: 61.33
Gene sequence:
>1443_bases GTGATTTCATACTTGGATGACGTATTTTTATTTGTGTGCGCAGGAATCGCGATTGCCCTTTCGGTGGGCTCTGCCGGTCA TGCCCTTGTCATGAAGCGAGACCCCCGGTCAGCACTCGGGTGGATCGTTGTCTGCCTCACGGTCCCGCTGTTCGGTCCCA TTTTCTACTGGAGCATGGGGGTAAACCGCATCTTCCGCCGGGCCCGCAAGTGGCAGGAAACAGGGCGCCGTCTGGCTGGG GGAGAGCACTTCCGCTCAGCCCAGGAGCATGAAAGTGCGCCGACTCCTCCGGCGGGGGCCGAATACCTCTCCGAGCTGCG CCATCTGGCCGATCGGGTGGTGGGAGCCCCTCTGGTCCAGGGAAACCGTATAATCCCCCTGGATGGTGGCGAAGGGGCGT ACCCCGCCATGCTGGAAGCCATCGCCCATGCCCGATCCTCGGTCCACCTTTCTACCTATATCTTCGATTCCGACAGCACC GGCCGCCGGTTCATCACTACGCTGGCCGCCGCCGCGGCGCGTGGTGTCATCGTGCGGGTGATCGTCGACGGCGTCGGTGA AAAGTATTCATGGCCCCGTGCCAGGACTCTCATGGAGGGGACGGGAATCAGGGTTGAGCGGTTCCTGCCGTTGCGACAGG GGATCTACATGAATCTGCGCAACCACCGCAAAGTCTTGGTGGTGGACGGCCAGCTGGCATTTACGGGGGGGATGAATATC GGGGACCGGCATGTGGCTGAAAAGGCGGGTGACGCCGTGTCGCGGGATGTTCACTTCTCGGTGGCGGGTCCGGTGGTGGC GGGGCTTCAGCAGGTCTTCCTTGAGGATTGGCACTTCGTCACCGGCGAACTTCTTGATGACACCCGGTATTTCCCTCCGA TCCAGCCGGCCGGTCATGCCCTGGCCCGTCCCATCGGCGACGGGCCCGACAAGGAATACCATACGCTCCATTGGATCATC ATGGGAGCCCTGTCGTGCGCCACTCGGACGGTTCAGATCATGACACCGTACTTCATCCCCGACCGCTCACTTGTTTCGGC CCTGGTCACTACGGCGTTGCGGGGGGTGGAGGTCACCCTCGTTTTGCCTGAGAAGAACAATCTTCCCTTTGTCCACTGGG CCACCAGGGCCTATCTCTGGGAGCTTATCCAGCAGGGAATCAGAGTGTTTTACCAGCCGCCCCCTTTTGCCCACACCAAG CTTTTCATCGTCGACGGCCTCTGGAGCATGATCGGCTCGGCCAACCTGGATCCCCGCAGCCTTCGGCTCAACTTCGAGCT CAATCTGGAGGTTTACGATCGGGAGTTGGCCGGAACCCTTTCCCGTCACTTCGCCGTAACCGTTGCCCGCTCGCGACAGG TGAGCCTGACCGAGATGGACGGCCGCCCACTCCCTGAAAAAGTGCGGGACGCCACGGCCAAGCTCTTTTCTCCCTATCTG TAG
Upstream 100 bases:
>100_bases AGTAAAGGGTCGGCAGGCATGCCGCAATGGGGCGGCTGTACACTGCCAGGCCGGAGCCCGCGTGCGACGAGGTTTTCGCA CCGCCGCCGAGGGATGGGGC
Downstream 100 bases:
>100_bases TCCTGGCTACAACGGCTCGCGGTATCGGGTCGCTGTCATTTCCGGTAGCGCTCGATGGCAACGAGTGCCCTGTCCAGAGC TGCCGGGCAGTGGGCCTCGA
Product: cardiolipin synthetase
Products: NA
Alternate protein names: CL synthase [H]
Number of amino acids: Translated: 480; Mature: 480
Protein sequence:
>480_residues MISYLDDVFLFVCAGIAIALSVGSAGHALVMKRDPRSALGWIVVCLTVPLFGPIFYWSMGVNRIFRRARKWQETGRRLAG GEHFRSAQEHESAPTPPAGAEYLSELRHLADRVVGAPLVQGNRIIPLDGGEGAYPAMLEAIAHARSSVHLSTYIFDSDST GRRFITTLAAAAARGVIVRVIVDGVGEKYSWPRARTLMEGTGIRVERFLPLRQGIYMNLRNHRKVLVVDGQLAFTGGMNI GDRHVAEKAGDAVSRDVHFSVAGPVVAGLQQVFLEDWHFVTGELLDDTRYFPPIQPAGHALARPIGDGPDKEYHTLHWII MGALSCATRTVQIMTPYFIPDRSLVSALVTTALRGVEVTLVLPEKNNLPFVHWATRAYLWELIQQGIRVFYQPPPFAHTK LFIVDGLWSMIGSANLDPRSLRLNFELNLEVYDRELAGTLSRHFAVTVARSRQVSLTEMDGRPLPEKVRDATAKLFSPYL
Sequences:
>Translated_480_residues MISYLDDVFLFVCAGIAIALSVGSAGHALVMKRDPRSALGWIVVCLTVPLFGPIFYWSMGVNRIFRRARKWQETGRRLAG GEHFRSAQEHESAPTPPAGAEYLSELRHLADRVVGAPLVQGNRIIPLDGGEGAYPAMLEAIAHARSSVHLSTYIFDSDST GRRFITTLAAAAARGVIVRVIVDGVGEKYSWPRARTLMEGTGIRVERFLPLRQGIYMNLRNHRKVLVVDGQLAFTGGMNI GDRHVAEKAGDAVSRDVHFSVAGPVVAGLQQVFLEDWHFVTGELLDDTRYFPPIQPAGHALARPIGDGPDKEYHTLHWII MGALSCATRTVQIMTPYFIPDRSLVSALVTTALRGVEVTLVLPEKNNLPFVHWATRAYLWELIQQGIRVFYQPPPFAHTK LFIVDGLWSMIGSANLDPRSLRLNFELNLEVYDRELAGTLSRHFAVTVARSRQVSLTEMDGRPLPEKVRDATAKLFSPYL >Mature_480_residues MISYLDDVFLFVCAGIAIALSVGSAGHALVMKRDPRSALGWIVVCLTVPLFGPIFYWSMGVNRIFRRARKWQETGRRLAG GEHFRSAQEHESAPTPPAGAEYLSELRHLADRVVGAPLVQGNRIIPLDGGEGAYPAMLEAIAHARSSVHLSTYIFDSDST GRRFITTLAAAAARGVIVRVIVDGVGEKYSWPRARTLMEGTGIRVERFLPLRQGIYMNLRNHRKVLVVDGQLAFTGGMNI GDRHVAEKAGDAVSRDVHFSVAGPVVAGLQQVFLEDWHFVTGELLDDTRYFPPIQPAGHALARPIGDGPDKEYHTLHWII MGALSCATRTVQIMTPYFIPDRSLVSALVTTALRGVEVTLVLPEKNNLPFVHWATRAYLWELIQQGIRVFYQPPPFAHTK LFIVDGLWSMIGSANLDPRSLRLNFELNLEVYDRELAGTLSRHFAVTVARSRQVSLTEMDGRPLPEKVRDATAKLFSPYL
Specific function: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]
COG id: COG1502
COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 PLD phosphodiesterase domains [H]
Homologues:
Organism=Escherichia coli, GI1787502, Length=484, Percent_Identity=30.3719008264463, Blast_Score=203, Evalue=2e-53, Organism=Escherichia coli, GI1787007, Length=353, Percent_Identity=30.5949008498584, Blast_Score=138, Evalue=9e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022924 - InterPro: IPR015679 - InterPro: IPR001736 [H]
Pfam domain/function: PF00614 PLDc [H]
EC number: 2.7.8.-
Molecular weight: Translated: 53269; Mature: 53269
Theoretical pI: Translated: 9.18; Mature: 9.18
Prosite motif: PS50035 PLD
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MISYLDDVFLFVCAGIAIALSVGSAGHALVMKRDPRSALGWIVVCLTVPLFGPIFYWSMG CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH VNRIFRRARKWQETGRRLAGGEHFRSAQEHESAPTPPAGAEYLSELRHLADRVVGAPLVQ HHHHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEC GNRIIPLDGGEGAYPAMLEAIAHARSSVHLSTYIFDSDSTGRRFITTLAAAAARGVIVRV CCEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEE IVDGVGEKYSWPRARTLMEGTGIRVERFLPLRQGIYMNLRNHRKVLVVDGQLAFTGGMNI EECCCCCCCCCCHHHHHHCCCCCCCEECCHHHHCCEEEECCCCEEEEECCEEEEECCCCC GDRHVAEKAGDAVSRDVHFSVAGPVVAGLQQVFLEDWHFVTGELLDDTRYFPPIQPAGHA CHHHHHHHHCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH LARPIGDGPDKEYHTLHWIIMGALSCATRTVQIMTPYFIPDRSLVSALVTTALRGVEVTL HHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCEECCCHHHHHHHHHHHHCCEEEEE VLPEKNNLPFVHWATRAYLWELIQQGIRVFYQPPPFAHTKLFIVDGLWSMIGSANLDPRS EEECCCCCCEEEHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEHHHHHHHCCCCCCCCE LRLNFELNLEVYDRELAGTLSRHFAVTVARSRQVSLTEMDGRPLPEKVRDATAKLFSPYL EEEEEEEEEEEECHHHHHHHHHHEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCC >Mature Secondary Structure MISYLDDVFLFVCAGIAIALSVGSAGHALVMKRDPRSALGWIVVCLTVPLFGPIFYWSMG CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH VNRIFRRARKWQETGRRLAGGEHFRSAQEHESAPTPPAGAEYLSELRHLADRVVGAPLVQ HHHHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEC GNRIIPLDGGEGAYPAMLEAIAHARSSVHLSTYIFDSDSTGRRFITTLAAAAARGVIVRV CCEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEE IVDGVGEKYSWPRARTLMEGTGIRVERFLPLRQGIYMNLRNHRKVLVVDGQLAFTGGMNI EECCCCCCCCCCHHHHHHCCCCCCCEECCHHHHCCEEEECCCCEEEEECCEEEEECCCCC GDRHVAEKAGDAVSRDVHFSVAGPVVAGLQQVFLEDWHFVTGELLDDTRYFPPIQPAGHA CHHHHHHHHCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH LARPIGDGPDKEYHTLHWIIMGALSCATRTVQIMTPYFIPDRSLVSALVTTALRGVEVTL HHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCEECCCHHHHHHHHHHHHCCEEEEE VLPEKNNLPFVHWATRAYLWELIQQGIRVFYQPPPFAHTKLFIVDGLWSMIGSANLDPRS EEECCCCCCEEEHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEHHHHHHHCCCCCCCCE LRLNFELNLEVYDRELAGTLSRHFAVTVARSRQVSLTEMDGRPLPEKVRDATAKLFSPYL EEEEEEEEEEEECHHHHHHHHHHEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferring phosphorus-containing groups [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA