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The map label for this gene is corA-2 [H]

Identifier: 39998411

GI number: 39998411

Start: 3648635

End: 3649588

Strand: Direct

Name: corA-2 [H]

Synonym: GSU3322

Alternate gene names: 39998411

Gene position: 3648635-3649588 (Clockwise)

Preceding gene: 39998410

Following gene: 39998412

Centisome position: 95.66

GC content: 57.23

Gene sequence:

>954_bases
ATGATCAAGGCATACCTTCGCGCGGAAGACACCTTCAGACCGGTGGCAGTGGAGTCCGATGAACTGGCGGAACTGGACAC
CGATACCCTCGTCTGGCTCGACCTCATGTCCCCCACGACCGAGGAGCTGGCCACGGTTGAGCGTTGCCTCAAGCTGGAAC
TGCCGACGCGGCAGGAGTCGGAGGAGATCGAGTTCAGCTCCCGCTACTGGGAGGACGAAACCGGCATCGACATCAACACC
TACTTCCTCGTGAAGCAGGATGACAAATACCATAACGAAACCGTTTCGTTCATCCTGAAGCGGCACTTCATCGTCACCAT
CCGGTTCAGCGACCACCGCATCTTCACCGAGTTCTCCCGCCGTCTCCGGCTCAATCCGCGCGCCTTCCGGGACGGGGCCG
ACATCCTCAACGGGATTCTCGCCATGCGGGTCGACATGGACGCCGACATCCTTGAGGCCCTGTCCAAGTCCATTGCCAGC
ATCGGCCGGAAAGAGCCCCAGTCCTTCGACAATCCGACCACGTTCCTCGAATACATCACCGACTACGAGGACATCAACAT
CACCATCCGCGAAAACCTCACGGACAAGCACCGGGTACTCTCGTCGCTCCTGAAGAGCACCATGATCAGCGAGCCCCTAA
AGAAAGAATTCAGCATGATGATGAAGGACGTGAACTCCCTCATCATCTCCGCCAACTTCAACTTCGAGCGGCTCGACTAC
CTGCAGAACCTCTTCCTGAACCACATGAGCGTGGAGCAGAACAAGGTCATCAAGATCTTCACCGTCATGTCGGTCATCTT
CCTGCCCCCCACCATGATCGCCAGCATCTACGGCATGAACTACAAGCACATGCCCGAGCTGGAGTGGGTGTTCGGCTATC
CATTCGCCCTGAGCCTCATCGTCCTCTCAGCGGTATTGCCCCTCTACATCTTCAAGAAGAAAGGGTGGCTGTAG

Upstream 100 bases:

>100_bases
TGACCGGAGAGGGCAGTGGCCGCTTGACCCCTGCCATCCTTGCATCTACAATCGTTGTAACGTGGCAACATCCTGAATTT
CTGGCAGAAAGCGGTGCACT

Downstream 100 bases:

>100_bases
CATGCCGCGCAAGGCACAGGCAGCCGGGACCGGCGCCCCGGAACCGACTGGCGCGCGCGCCCCGGAGACGAGCCTTGCCT
CGCCCGAGCTCTACCTGAAC

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MIKAYLRAEDTFRPVAVESDELAELDTDTLVWLDLMSPTTEELATVERCLKLELPTRQESEEIEFSSRYWEDETGIDINT
YFLVKQDDKYHNETVSFILKRHFIVTIRFSDHRIFTEFSRRLRLNPRAFRDGADILNGILAMRVDMDADILEALSKSIAS
IGRKEPQSFDNPTTFLEYITDYEDINITIRENLTDKHRVLSSLLKSTMISEPLKKEFSMMMKDVNSLIISANFNFERLDY
LQNLFLNHMSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALSLIVLSAVLPLYIFKKKGWL

Sequences:

>Translated_317_residues
MIKAYLRAEDTFRPVAVESDELAELDTDTLVWLDLMSPTTEELATVERCLKLELPTRQESEEIEFSSRYWEDETGIDINT
YFLVKQDDKYHNETVSFILKRHFIVTIRFSDHRIFTEFSRRLRLNPRAFRDGADILNGILAMRVDMDADILEALSKSIAS
IGRKEPQSFDNPTTFLEYITDYEDINITIRENLTDKHRVLSSLLKSTMISEPLKKEFSMMMKDVNSLIISANFNFERLDY
LQNLFLNHMSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALSLIVLSAVLPLYIFKKKGWL
>Mature_317_residues
MIKAYLRAEDTFRPVAVESDELAELDTDTLVWLDLMSPTTEELATVERCLKLELPTRQESEEIEFSSRYWEDETGIDINT
YFLVKQDDKYHNETVSFILKRHFIVTIRFSDHRIFTEFSRRLRLNPRAFRDGADILNGILAMRVDMDADILEALSKSIAS
IGRKEPQSFDNPTTFLEYITDYEDINITIRENLTDKHRVLSSLLKSTMISEPLKKEFSMMMKDVNSLIISANFNFERLDY
LQNLFLNHMSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALSLIVLSAVLPLYIFKKKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=290, Percent_Identity=31.7241379310345, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37063; Mature: 37063

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAYLRAEDTFRPVAVESDELAELDTDTLVWLDLMSPTTEELATVERCLKLELPTRQES
CCEEEEECCCCCCCEEECCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCC
EEIEFSSRYWEDETGIDINTYFLVKQDDKYHNETVSFILKRHFIVTIRFSDHRIFTEFSR
HHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCEEEEEEEECCCHHHHHHHH
RLRLNPRAFRDGADILNGILAMRVDMDADILEALSKSIASIGRKEPQSFDNPTTFLEYIT
HHCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHC
DYEDINITIRENLTDKHRVLSSLLKSTMISEPLKKEFSMMMKDVNSLIISANFNFERLDY
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHH
LQNLFLNHMSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALSLI
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEECCHHHHHHH
VLSAVLPLYIFKKKGWL
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIKAYLRAEDTFRPVAVESDELAELDTDTLVWLDLMSPTTEELATVERCLKLELPTRQES
CCEEEEECCCCCCCEEECCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCC
EEIEFSSRYWEDETGIDINTYFLVKQDDKYHNETVSFILKRHFIVTIRFSDHRIFTEFSR
HHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCEEEEEEEECCCHHHHHHHH
RLRLNPRAFRDGADILNGILAMRVDMDADILEALSKSIASIGRKEPQSFDNPTTFLEYIT
HHCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHC
DYEDINITIRENLTDKHRVLSSLLKSTMISEPLKKEFSMMMKDVNSLIISANFNFERLDY
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHH
LQNLFLNHMSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALSLI
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEECCHHHHHHH
VLSAVLPLYIFKKKGWL
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]