Click here to switch to the map view.

The map label for this gene is gpmA

Identifier: 39998297

GI number: 39998297

Start: 3513216

End: 3514757

Strand: Reverse

Name: gpmA

Synonym: GSU3207

Alternate gene names: 39998297

Gene position: 3514757-3513216 (Counterclockwise)

Preceding gene: 39998298

Following gene: 39998281

Centisome position: 92.15

GC content: 65.5

Gene sequence:

>1542_bases
ATGCCCAGACCGCTCGTGCTCATGATCCTCGACGGGTGGGGGATCAATCCCGACCCTTCCAATAATGCCGTGGCCATTGG
CCGGACCCCGGCCATGGACCGCCTCATGGCCGAGTACCCCTCGGTGGAGATGGAGACGTCGGGCATGGCTGTGGGGCTTC
CCGACGGCCAAATGGGGAACTCGGAGGTGGGCCACCTGAACATCGGCGCCGGCCGTGTGGTCTACCAGGACCTGACCCGC
ATCACCAAATCGATCGACGACGGCGACTTCTTCACCAATCCGGTGCTTCTCGACTGCATGGCCCGCGTCAAGGCTGCCGG
CGGCAGGCTGCACCTGGGCGGGCTCCTCTCCGACGGGGGAGTCCACTCCCATAACACGCACCTCTATGCCCTCATTGAGT
TGGCCCGGCGTCAGGGGGTGAAGGACGTGTTCGTTCATGCCTTCCTCGACGGCCGCGACACCCCGCCCAGCAGCGGTGCG
GGCTACCTGGCCGAGCTGGAGGCGGAGATCGGCCGGATCGGCTTCGGCAGGGTCGCCACGGTCATGGGGCGCTACTGGGC
CATGGACCGGGATAATCGCTGGGAGCGGGTGGAGCGGGCCTATAACACCATTGTCAAGGGTGAGGGGGCGCACCGTCCGG
ACTCGGCTGCGGCCATCGAGGCGAGTTACAGTGCCGGTGTCACTGACGAGTTCGTTGAGCCGGCCGTCATCGCCCCTAAC
GGCAGCCCACTCGGACTTCTCGCCGACGGGGACGGCTTTATCTGCTTCAATTTCCGTTCGGACCGGGCCCGTGAGATCAC
CCGGGCACTCACGGACCCCGCCTTCGCCGGCTTCGATCGTTCACCGTGGCCCCGCCTCGCCTCCTATGTCTGCCTTACTG
AGTACGATGCCACCTTTCCGCTCCCCGTGGCCTACCCCCCCGAAAGCCTCGCCAACATCCTGGGCCAGGTGGTGAGCCGG
GCCGGGCTCCGGCAGCTGCGGATCGCCGAGACCGAAAAGTATGCCCACGTCACGTTCTTCTTCAACGGCGGCGTGGAAGA
GCCGTTTCCCGGCGAGGAGCGGATCCTGATCCCCTCTCCCAAGGAAGTGGCCACCTACGACCAGAAGCCGGAAATGAGCG
CCCCGCTCGTGACCGATGCGCTGCTGAAGCGGATCGACGAGGGAGTAGACGATGTGGTGGTGGTCAATTTCGCCAATGCC
GACATGGTGGGACACACCGGCATCCTTGATGCCGCCGTGCGCGCCATCGAGACGGTTGACGAGTGCGTGGGCCGGGTGGC
GGCAACGGTGCTGGAAAAGGGGGGGGCACTGATCATAACTGCCGACCACGGCAACGCCGAGATGATGGTGGACGAGACCG
GCGGTCCCCACACCGCCCATACCAACGAACGGGTACCACTCATCCTGGTGGACGATTCCCGGAAAGGGGCACGACTGCGG
CCCGGGACCCTAGCCGACATCGCGCCGACCATGCTTGGGTTACTGGGGATTCCGCAGCCGCCGGAGATGACGGGGAAAAG
CTTGCTGGTCGCTACCGAGTGA

Upstream 100 bases:

>100_bases
CCACCAGATGGTCCGGGTGGTGCTGCTGGAGCAGATCTACCGGGCTTTCACCATCATCGGCAACGAACCCTATCATCACT
AATCCTGTCACGGAGGAGCA

Downstream 100 bases:

>100_bases
TGGTTGTGGCGGTATTTTGACTCCCAGGTCAGAGGCGACAAAAAAGGGCGCTGTCGGCAGCGCCCTTTTTCTCTCGGTCC
GCTCGAGAGGCTGTCAGGCC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MPRPLVLMILDGWGINPDPSNNAVAIGRTPAMDRLMAEYPSVEMETSGMAVGLPDGQMGNSEVGHLNIGAGRVVYQDLTR
ITKSIDDGDFFTNPVLLDCMARVKAAGGRLHLGGLLSDGGVHSHNTHLYALIELARRQGVKDVFVHAFLDGRDTPPSSGA
GYLAELEAEIGRIGFGRVATVMGRYWAMDRDNRWERVERAYNTIVKGEGAHRPDSAAAIEASYSAGVTDEFVEPAVIAPN
GSPLGLLADGDGFICFNFRSDRAREITRALTDPAFAGFDRSPWPRLASYVCLTEYDATFPLPVAYPPESLANILGQVVSR
AGLRQLRIAETEKYAHVTFFFNGGVEEPFPGEERILIPSPKEVATYDQKPEMSAPLVTDALLKRIDEGVDDVVVVNFANA
DMVGHTGILDAAVRAIETVDECVGRVAATVLEKGGALIITADHGNAEMMVDETGGPHTAHTNERVPLILVDDSRKGARLR
PGTLADIAPTMLGLLGIPQPPEMTGKSLLVATE

Sequences:

>Translated_513_residues
MPRPLVLMILDGWGINPDPSNNAVAIGRTPAMDRLMAEYPSVEMETSGMAVGLPDGQMGNSEVGHLNIGAGRVVYQDLTR
ITKSIDDGDFFTNPVLLDCMARVKAAGGRLHLGGLLSDGGVHSHNTHLYALIELARRQGVKDVFVHAFLDGRDTPPSSGA
GYLAELEAEIGRIGFGRVATVMGRYWAMDRDNRWERVERAYNTIVKGEGAHRPDSAAAIEASYSAGVTDEFVEPAVIAPN
GSPLGLLADGDGFICFNFRSDRAREITRALTDPAFAGFDRSPWPRLASYVCLTEYDATFPLPVAYPPESLANILGQVVSR
AGLRQLRIAETEKYAHVTFFFNGGVEEPFPGEERILIPSPKEVATYDQKPEMSAPLVTDALLKRIDEGVDDVVVVNFANA
DMVGHTGILDAAVRAIETVDECVGRVAATVLEKGGALIITADHGNAEMMVDETGGPHTAHTNERVPLILVDDSRKGARLR
PGTLADIAPTMLGLLGIPQPPEMTGKSLLVATE
>Mature_512_residues
PRPLVLMILDGWGINPDPSNNAVAIGRTPAMDRLMAEYPSVEMETSGMAVGLPDGQMGNSEVGHLNIGAGRVVYQDLTRI
TKSIDDGDFFTNPVLLDCMARVKAAGGRLHLGGLLSDGGVHSHNTHLYALIELARRQGVKDVFVHAFLDGRDTPPSSGAG
YLAELEAEIGRIGFGRVATVMGRYWAMDRDNRWERVERAYNTIVKGEGAHRPDSAAAIEASYSAGVTDEFVEPAVIAPNG
SPLGLLADGDGFICFNFRSDRAREITRALTDPAFAGFDRSPWPRLASYVCLTEYDATFPLPVAYPPESLANILGQVVSRA
GLRQLRIAETEKYAHVTFFFNGGVEEPFPGEERILIPSPKEVATYDQKPEMSAPLVTDALLKRIDEGVDDVVVVNFANAD
MVGHTGILDAAVRAIETVDECVGRVAATVLEKGGALIITADHGNAEMMVDETGGPHTAHTNERVPLILVDDSRKGARLRP
GTLADIAPTMLGLLGIPQPPEMTGKSLLVATE

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=510, Percent_Identity=52.9411764705882, Blast_Score=535, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI32564249, Length=515, Percent_Identity=45.8252427184466, Blast_Score=456, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17507741, Length=515, Percent_Identity=45.8252427184466, Blast_Score=456, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_GEOSL (Q747Q8)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_954248.1
- ProteinModelPortal:   Q747Q8
- SMR:   Q747Q8
- GeneID:   2688345
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU3207
- NMPDR:   fig|243231.1.peg.3186
- TIGR:   GSU3207
- HOGENOM:   HBG613255
- OMA:   DNKTDEF
- ProtClustDB:   PRK05434
- BioCyc:   GSUL243231:GSU_3207-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 55134; Mature: 55003

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: ACT_SITE 61-61

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPLVLMILDGWGINPDPSNNAVAIGRTPAMDRLMAEYPSVEMETSGMAVGLPDGQMGN
CCCCEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHCCCCEEECCCEEEECCCCCCCC
SEVGHLNIGAGRVVYQDLTRITKSIDDGDFFTNPVLLDCMARVKAAGGRLHLGGLLSDGG
CCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECEEECCCC
VHSHNTHLYALIELARRQGVKDVFVHAFLDGRDTPPSSGAGYLAELEAEIGRIGFGRVAT
CCCCCCHHHHHHHHHHHCCCHHEEHHHEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHH
VMGRYWAMDRDNRWERVERAYNTIVKGEGAHRPDSAAAIEASYSAGVTDEFVEPAVIAPN
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHCCCEEECCC
GSPLGLLADGDGFICFNFRSDRAREITRALTDPAFAGFDRSPWPRLASYVCLTEYDATFP
CCCEEEEECCCCEEEEECCCCHHHHHHHHHCCCHHCCCCCCCCHHHHHEEEEEECCCCCC
LPVAYPPESLANILGQVVSRAGLRQLRIAETEKYAHVTFFFNGGVEEPFPGEERILIPSP
CCCCCCHHHHHHHHHHHHHHHCHHHEEEECCCCEEEEEEEEECCCCCCCCCCCEEECCCC
KEVATYDQKPEMSAPLVTDALLKRIDEGVDDVVVVNFANADMVGHTGILDAAVRAIETVD
HHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
ECVGRVAATVLEKGGALIITADHGNAEMMVDETGGPHTAHTNERVPLILVDDSRKGARLR
HHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCC
PGTLADIAPTMLGLLGIPQPPEMTGKSLLVATE
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
PRPLVLMILDGWGINPDPSNNAVAIGRTPAMDRLMAEYPSVEMETSGMAVGLPDGQMGN
CCCEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHCCCCEEECCCEEEECCCCCCCC
SEVGHLNIGAGRVVYQDLTRITKSIDDGDFFTNPVLLDCMARVKAAGGRLHLGGLLSDGG
CCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEECEEECCCC
VHSHNTHLYALIELARRQGVKDVFVHAFLDGRDTPPSSGAGYLAELEAEIGRIGFGRVAT
CCCCCCHHHHHHHHHHHCCCHHEEHHHEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHH
VMGRYWAMDRDNRWERVERAYNTIVKGEGAHRPDSAAAIEASYSAGVTDEFVEPAVIAPN
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHCCCEEECCC
GSPLGLLADGDGFICFNFRSDRAREITRALTDPAFAGFDRSPWPRLASYVCLTEYDATFP
CCCEEEEECCCCEEEEECCCCHHHHHHHHHCCCHHCCCCCCCCHHHHHEEEEEECCCCCC
LPVAYPPESLANILGQVVSRAGLRQLRIAETEKYAHVTFFFNGGVEEPFPGEERILIPSP
CCCCCCHHHHHHHHHHHHHHHCHHHEEEECCCCEEEEEEEEECCCCCCCCCCCEEECCCC
KEVATYDQKPEMSAPLVTDALLKRIDEGVDDVVVVNFANADMVGHTGILDAAVRAIETVD
HHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
ECVGRVAATVLEKGGALIITADHGNAEMMVDETGGPHTAHTNERVPLILVDDSRKGARLR
HHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCC
PGTLADIAPTMLGLLGIPQPPEMTGKSLLVATE
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA