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The map label for this gene is rlmH

Identifier: 39998298

GI number: 39998298

Start: 3514776

End: 3515237

Strand: Reverse

Name: rlmH

Synonym: GSU3208

Alternate gene names: 39998298

Gene position: 3515237-3514776 (Counterclockwise)

Preceding gene: 39998299

Following gene: 39998297

Centisome position: 92.16

GC content: 65.15

Gene sequence:

>462_bases
GTGAAACTGCGCGTGCTCTGGGTCGGCAAGACCCAGGAGGAGTGGGTTCGGCGCGGCATTGACGAATATGCCGGCCGGGT
GAGACGCTATGCTCCCCTGGAGATCGGCGAGGCGCGGGATGAAAAGGGCGCTGCGGCCGAGGCCATGCGCGCTCGGGAGT
GTGAGCGGCTCGACAAGCTCGTTCCCCGCACCTCACGCCTGATCCTTCTGGATGAGCGGGGCGATCAGCTCACTTCGCCG
GAATTCGCCGCCTACATCTCCCGTTGCCGGGACACGGCGGTACCCGAACTGGCCTTCGCCATCGGCGGGGCCTACGGCTT
TGCCGACGAGTTCAGGCGCCGGGCCGACCGGGTCATCGCCCTGTCGCGGATGACCTTTACCCACCAGATGGTCCGGGTGG
TGCTGCTGGAGCAGATCTACCGGGCTTTCACCATCATCGGCAACGAACCCTATCATCACTAA

Upstream 100 bases:

>100_bases
GCCGGGCAGGTGGCGATTCCCGCGGAGTACCTGTGGGAAGGGAAGGAAGGGGGAGGGGAGTGATCCTCGCCCTCTCCGTG
CCGGCCGGGGTCGGAGCGCC

Downstream 100 bases:

>100_bases
TCCTGTCACGGAGGAGCAATGCCCAGACCGCTCGTGCTCATGATCCTCGACGGGTGGGGGATCAATCCCGACCCTTCCAA
TAATGCCGTGGCCATTGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MKLRVLWVGKTQEEWVRRGIDEYAGRVRRYAPLEIGEARDEKGAAAEAMRARECERLDKLVPRTSRLILLDERGDQLTSP
EFAAYISRCRDTAVPELAFAIGGAYGFADEFRRRADRVIALSRMTFTHQMVRVVLLEQIYRAFTIIGNEPYHH

Sequences:

>Translated_153_residues
MKLRVLWVGKTQEEWVRRGIDEYAGRVRRYAPLEIGEARDEKGAAAEAMRARECERLDKLVPRTSRLILLDERGDQLTSP
EFAAYISRCRDTAVPELAFAIGGAYGFADEFRRRADRVIALSRMTFTHQMVRVVLLEQIYRAFTIIGNEPYHH
>Mature_153_residues
MKLRVLWVGKTQEEWVRRGIDEYAGRVRRYAPLEIGEARDEKGAAAEAMRARECERLDKLVPRTSRLILLDERGDQLTSP
EFAAYISRCRDTAVPELAFAIGGAYGFADEFRRRADRVIALSRMTFTHQMVRVVLLEQIYRAFTIIGNEPYHH

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=154, Percent_Identity=31.1688311688312, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_GEOSL (Q747Q7)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_954249.1
- ProteinModelPortal:   Q747Q7
- SMR:   Q747Q7
- GeneID:   2688350
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU3208
- NMPDR:   fig|243231.1.peg.3187
- TIGR:   GSU3208
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- ProtClustDB:   CLSK829160
- BioCyc:   GSUL243231:GSU_3208-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 17701; Mature: 17701

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRVLWVGKTQEEWVRRGIDEYAGRVRRYAPLEIGEARDEKGAAAEAMRARECERLDKL
CEEEEEEECCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VPRTSRLILLDERGDQLTSPEFAAYISRCRDTAVPELAFAIGGAYGFADEFRRRADRVIA
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHH
LSRMTFTHQMVRVVLLEQIYRAFTIIGNEPYHH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLRVLWVGKTQEEWVRRGIDEYAGRVRRYAPLEIGEARDEKGAAAEAMRARECERLDKL
CEEEEEEECCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VPRTSRLILLDERGDQLTSPEFAAYISRCRDTAVPELAFAIGGAYGFADEFRRRADRVIA
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHH
LSRMTFTHQMVRVVLLEQIYRAFTIIGNEPYHH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA