| Definition | Geobacter sulfurreducens PCA chromosome, complete genome. |
|---|---|
| Accession | NC_002939 |
| Length | 3,814,139 |
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The map label for this gene is mrcA [H]
Identifier: 39998223
GI number: 39998223
Start: 3435686
End: 3438076
Strand: Reverse
Name: mrcA [H]
Synonym: GSU3133
Alternate gene names: 39998223
Gene position: 3438076-3435686 (Counterclockwise)
Preceding gene: 39998225
Following gene: 39998222
Centisome position: 90.14
GC content: 61.23
Gene sequence:
>2391_bases TTGAAAATTGTTGCTATAACATCGATATGTCTTGCGGTGGCAGCCCTGCTCGCGCTGGGGGGATATCTGTTCTACCTCAT GGCGACCCTCCCGAAAGTGGACCGGTTGGCCGATTACAAGCCTCCCATCGTTTCCCAGGTTTTCGGCGACGATGGGAGCC TGGTGGGAGAGTTCTATCTGGAACGGCGGACGGTGGTGCCGGTGGAGAAGCTGCCTCGCCGGCTCGTCCAGGCTTTTGTC TCGGCCGAGGATTCCAACTTCTACCAGCACAAGGGTCTGGATTACGTGGGCATTGTCCGGGCCGCGGTTAAAAACCTCAT CTCCCTGCGCAAAAAAGAGGGGGCATCGACCATTACCCAGCAAGTGGCCAAGTCAATGCTCCTTACCCCCGAGAAGAGCT ACACCCGCAAACTCAAGGAGGCGGTTCTCGCCAAACGGATGGAGGAGCGGCTTTCCAAGGACGATATCCTCTATATATAT CTGAACCAGATTTATCTTGGCGCCGGTTCGTACGGCGTCCAGGTGGCGGCGGAGACCTACTTCGGCAAGAACGTCGAGCA ACTGAACCTGGCCGAAATGGCAATGCTCGCAGGCTTGCCCAAGGCCCCCAACGCCTATTCTCCCATCAAGCATCTTGACC GGGCGCGGGAACGCCAGGCCTATGTCCTTGAACGGATGGTAAAGGAAGGCTACGTCACCCAGGCCGAGGCGGATCATGCC CGGGCCACTCCCATCGTCATCCAGTCCATGAAGAAGGTCAACAGCGAACAGTCCGCCTATTTCCTGGAGCATATCCGGAT CGCCTTGGAAGACCGCTACGGTGAGGAGCAGCTTTACAAGGAAGGGTTGCGGATTTACACCACCATGAACGCCGAGATGC AGAAGGCGGCCTATGAGGCGGTGGTGAACGGTCTCAAGAACGTGGACAAGCGGCAGGGATTCCGCGGCGCAACGGCCTAT CTGGCCGAGGCTGCGGTGGCTGCAGTCTGCGATAAGGTGGAAGACGGCATCGATACTGTTTCTCTCAAGCAGGGAGCCAC CTACCAGGGGGTGGTCACCGCCGTGGACCCCGTCCGGGGGGACGTGACCGTACGGGTCGGTGACCGCACCGGCACTCTCT CGCGCAAGAATATGGCCTGGGCCGGCAAGGTGCAGTTGGTGAACGCCTGGGGCAAGCAGGAGGTGAAGGGTAAATTCCTG TCGCTCGGCAGCGTGATCCTCGTATCGGTCGTTACCCCCGACGCGGACAAGAAAGGGGCTGTCTTTGCCCTTGATCAGGA ACCCGAGGCCCAGGCGGCAGTGGTGGCGCTGGATCCCCTCTCCGGCGCGGTCAAGGCGATGGTCGGGGGGTACGACTTCC GCAAAAGCCAGTTCAACCGGGCATTGCAGGCAAAGCGTAATCCCGGCTCCGCGTTCAAGCCGCTTATCTATGCCGCCGCC CTGGACAAGGGGATTACCCCTGCCACCATCTTCGACGACTCGCCGGTGGAGTATGAAAGCGGCAAGGAAAAGGCCTGGAA ACCCAAAAACTACGACAACATCTACCGGGGCAACGTGACCATGCGGGAGGCCCTCACCAACTCCATCAACGTGGTGAGCG TCAAGATCCTGGAGCAGATCGGCGTGGACTATGCCATCGAGTACGCCAAGAAGCTGGGCATAACGTCTCCCCTTTCGGCC AACCTGACCCTGGCCCTGGGCTCTTCCAGTCTTACCCCTCTTGAGCTGACCTCTGCCTACGCGGTGTTCGCTTCGGGCGG GTATCGGACCACCCCCTACTTCGTCACCAGGGTCGAGGATGCGGAAGGGCGGACTCTTGAGGAAACAGCACCGCCGGTCA TTCCCAGATTCTCCGTCATGACGTCGGCCGAATCGTCTCCCCTCGAGGCGTCGCCCGCCCCTCCGGCCACGGCCGGGGAC TCGGCGTCAACGGCGGTGCCGGTGATTGCGCCTGAAACCGCCTACATCATGACCAATCTCATGGAAAGCGTTGTCCAGAG CGGTACCGGACAGCGCGCCAGGGCCGTCGGCCGGCCGGTGGCCGGCAAGACCGGAACCACCAACGATATGAAAGATGCAT GGTTCGTGGGGTACATCCCCCAACTGGTGGCCGGAGTCTGGGTCGGCTACGATCAGGAGCGCTCCCTGGGGGCCGGCGGA TCGGGCGGACAGGCTGCGGCTCCCATCTGGACCGAATTCATGCGGCGGGCGGTGGCCGGGATTCCTTCCCGCGACTTCGA GACGCCTCCCAACGTTACTTTTGCCACCATCAATCCCCGCACCGGTCGGCTGGCCCGGGAGGGAAGCGACGGCGCCGTGC AGGAGTGCTTCATTGCGGGCACCGAACCGACCGCTTACGATGGTGAATCCTCCGAGGATGGTGTGCCATAA
Upstream 100 bases:
>100_bases TTCAACATCTTCAAATCAGGGAATTTGGTGGCGCTCGATGACAGTTGGTAGGCAGAACCCCGGTCCCCGGAACATAAACC GTCGACGGGGCAAAAGTCCA
Downstream 100 bases:
>100_bases ATACTTGTGATATCAGCATGTTAATATGTAGAGTTCGCGCCAGTGCTGGAGTTGCGGACGTCAGGTGGCCAAAAAACCTG ATACGGTAAGGGTTTCCGCC
Product: 1A family penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 796; Mature: 796
Protein sequence:
>796_residues MKIVAITSICLAVAALLALGGYLFYLMATLPKVDRLADYKPPIVSQVFGDDGSLVGEFYLERRTVVPVEKLPRRLVQAFV SAEDSNFYQHKGLDYVGIVRAAVKNLISLRKKEGASTITQQVAKSMLLTPEKSYTRKLKEAVLAKRMEERLSKDDILYIY LNQIYLGAGSYGVQVAAETYFGKNVEQLNLAEMAMLAGLPKAPNAYSPIKHLDRARERQAYVLERMVKEGYVTQAEADHA RATPIVIQSMKKVNSEQSAYFLEHIRIALEDRYGEEQLYKEGLRIYTTMNAEMQKAAYEAVVNGLKNVDKRQGFRGATAY LAEAAVAAVCDKVEDGIDTVSLKQGATYQGVVTAVDPVRGDVTVRVGDRTGTLSRKNMAWAGKVQLVNAWGKQEVKGKFL SLGSVILVSVVTPDADKKGAVFALDQEPEAQAAVVALDPLSGAVKAMVGGYDFRKSQFNRALQAKRNPGSAFKPLIYAAA LDKGITPATIFDDSPVEYESGKEKAWKPKNYDNIYRGNVTMREALTNSINVVSVKILEQIGVDYAIEYAKKLGITSPLSA NLTLALGSSSLTPLELTSAYAVFASGGYRTTPYFVTRVEDAEGRTLEETAPPVIPRFSVMTSAESSPLEASPAPPATAGD SASTAVPVIAPETAYIMTNLMESVVQSGTGQRARAVGRPVAGKTGTTNDMKDAWFVGYIPQLVAGVWVGYDQERSLGAGG SGGQAAAPIWTEFMRRAVAGIPSRDFETPPNVTFATINPRTGRLAREGSDGAVQECFIAGTEPTAYDGESSEDGVP
Sequences:
>Translated_796_residues MKIVAITSICLAVAALLALGGYLFYLMATLPKVDRLADYKPPIVSQVFGDDGSLVGEFYLERRTVVPVEKLPRRLVQAFV SAEDSNFYQHKGLDYVGIVRAAVKNLISLRKKEGASTITQQVAKSMLLTPEKSYTRKLKEAVLAKRMEERLSKDDILYIY LNQIYLGAGSYGVQVAAETYFGKNVEQLNLAEMAMLAGLPKAPNAYSPIKHLDRARERQAYVLERMVKEGYVTQAEADHA RATPIVIQSMKKVNSEQSAYFLEHIRIALEDRYGEEQLYKEGLRIYTTMNAEMQKAAYEAVVNGLKNVDKRQGFRGATAY LAEAAVAAVCDKVEDGIDTVSLKQGATYQGVVTAVDPVRGDVTVRVGDRTGTLSRKNMAWAGKVQLVNAWGKQEVKGKFL SLGSVILVSVVTPDADKKGAVFALDQEPEAQAAVVALDPLSGAVKAMVGGYDFRKSQFNRALQAKRNPGSAFKPLIYAAA LDKGITPATIFDDSPVEYESGKEKAWKPKNYDNIYRGNVTMREALTNSINVVSVKILEQIGVDYAIEYAKKLGITSPLSA NLTLALGSSSLTPLELTSAYAVFASGGYRTTPYFVTRVEDAEGRTLEETAPPVIPRFSVMTSAESSPLEASPAPPATAGD SASTAVPVIAPETAYIMTNLMESVVQSGTGQRARAVGRPVAGKTGTTNDMKDAWFVGYIPQLVAGVWVGYDQERSLGAGG SGGQAAAPIWTEFMRRAVAGIPSRDFETPPNVTFATINPRTGRLAREGSDGAVQECFIAGTEPTAYDGESSEDGVP >Mature_796_residues MKIVAITSICLAVAALLALGGYLFYLMATLPKVDRLADYKPPIVSQVFGDDGSLVGEFYLERRTVVPVEKLPRRLVQAFV SAEDSNFYQHKGLDYVGIVRAAVKNLISLRKKEGASTITQQVAKSMLLTPEKSYTRKLKEAVLAKRMEERLSKDDILYIY LNQIYLGAGSYGVQVAAETYFGKNVEQLNLAEMAMLAGLPKAPNAYSPIKHLDRARERQAYVLERMVKEGYVTQAEADHA RATPIVIQSMKKVNSEQSAYFLEHIRIALEDRYGEEQLYKEGLRIYTTMNAEMQKAAYEAVVNGLKNVDKRQGFRGATAY LAEAAVAAVCDKVEDGIDTVSLKQGATYQGVVTAVDPVRGDVTVRVGDRTGTLSRKNMAWAGKVQLVNAWGKQEVKGKFL SLGSVILVSVVTPDADKKGAVFALDQEPEAQAAVVALDPLSGAVKAMVGGYDFRKSQFNRALQAKRNPGSAFKPLIYAAA LDKGITPATIFDDSPVEYESGKEKAWKPKNYDNIYRGNVTMREALTNSINVVSVKILEQIGVDYAIEYAKKLGITSPLSA NLTLALGSSSLTPLELTSAYAVFASGGYRTTPYFVTRVEDAEGRTLEETAPPVIPRFSVMTSAESSPLEASPAPPATAGD SASTAVPVIAPETAYIMTNLMESVVQSGTGQRARAVGRPVAGKTGTTNDMKDAWFVGYIPQLVAGVWVGYDQERSLGAGG SGGQAAAPIWTEFMRRAVAGIPSRDFETPPNVTFATINPRTGRLAREGSDGAVQECFIAGTEPTAYDGESSEDGVP
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=838, Percent_Identity=36.2768496420048, Blast_Score=489, Evalue=1e-139, Organism=Escherichia coli, GI1786343, Length=256, Percent_Identity=35.9375, Blast_Score=149, Evalue=7e-37, Organism=Escherichia coli, GI1788867, Length=186, Percent_Identity=35.4838709677419, Blast_Score=113, Evalue=6e-26, Organism=Escherichia coli, GI1789601, Length=189, Percent_Identity=33.8624338624339, Blast_Score=97, Evalue=6e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 86081; Mature: 86081
Theoretical pI: Translated: 7.94; Mature: 7.94
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKIVAITSICLAVAALLALGGYLFYLMATLPKVDRLADYKPPIVSQVFGDDGSLVGEFYL CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHCCCCCHHHHHHH ERRTVVPVEKLPRRLVQAFVSAEDSNFYQHKGLDYVGIVRAAVKNLISLRKKEGASTITQ HCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH QVAKSMLLTPEKSYTRKLKEAVLAKRMEERLSKDDILYIYLNQIYLGAGSYGVQVAAETY HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEHHH FGKNVEQLNLAEMAMLAGLPKAPNAYSPIKHLDRARERQAYVLERMVKEGYVTQAEADHA CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC RATPIVIQSMKKVNSEQSAYFLEHIRIALEDRYGEEQLYKEGLRIYTTMNAEMQKAAYEA CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCHHHHHHHHHH VVNGLKNVDKRQGFRGATAYLAEAAVAAVCDKVEDGIDTVSLKQGATYQGVVTAVDPVRG HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCC DVTVRVGDRTGTLSRKNMAWAGKVQLVNAWGKQEVKGKFLSLGSVILVSVVTPDADKKGA CEEEEECCCCCCCCCCCCCEECCEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCC VFALDQEPEAQAAVVALDPLSGAVKAMVGGYDFRKSQFNRALQAKRNPGSAFKPLIYAAA EEEECCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH LDKGITPATIFDDSPVEYESGKEKAWKPKNYDNIYRGNVTMREALTNSINVVSVKILEQI HHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHCCCCCEEHHHHHHHH GVDYAIEYAKKLGITSPLSANLTLALGSSSLTPLELTSAYAVFASGGYRTTPYFVTRVED CHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHEEEEECCCCCCCCEEEEEEEC AEGRTLEETAPPVIPRFSVMTSAESSPLEASPAPPATAGDSASTAVPVIAPETAYIMTNL CCCCCCHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH MESVVQSGTGQRARAVGRPVAGKTGTTNDMKDAWFVGYIPQLVAGVWVGYDQERSLGAGG HHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC SGGQAAAPIWTEFMRRAVAGIPSRDFETPPNVTFATINPRTGRLAREGSDGAVQECFIAG CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHEEEC TEPTAYDGESSEDGVP CCCCCCCCCCCCCCCC >Mature Secondary Structure MKIVAITSICLAVAALLALGGYLFYLMATLPKVDRLADYKPPIVSQVFGDDGSLVGEFYL CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHCCCCCHHHHHHH ERRTVVPVEKLPRRLVQAFVSAEDSNFYQHKGLDYVGIVRAAVKNLISLRKKEGASTITQ HCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH QVAKSMLLTPEKSYTRKLKEAVLAKRMEERLSKDDILYIYLNQIYLGAGSYGVQVAAETY HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEHHH FGKNVEQLNLAEMAMLAGLPKAPNAYSPIKHLDRARERQAYVLERMVKEGYVTQAEADHA CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC RATPIVIQSMKKVNSEQSAYFLEHIRIALEDRYGEEQLYKEGLRIYTTMNAEMQKAAYEA CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCHHHHHHHHHH VVNGLKNVDKRQGFRGATAYLAEAAVAAVCDKVEDGIDTVSLKQGATYQGVVTAVDPVRG HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCC DVTVRVGDRTGTLSRKNMAWAGKVQLVNAWGKQEVKGKFLSLGSVILVSVVTPDADKKGA CEEEEECCCCCCCCCCCCCEECCEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCC VFALDQEPEAQAAVVALDPLSGAVKAMVGGYDFRKSQFNRALQAKRNPGSAFKPLIYAAA EEEECCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH LDKGITPATIFDDSPVEYESGKEKAWKPKNYDNIYRGNVTMREALTNSINVVSVKILEQI HHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHCCCCCEEHHHHHHHH GVDYAIEYAKKLGITSPLSANLTLALGSSSLTPLELTSAYAVFASGGYRTTPYFVTRVED CHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHEEEEECCCCCCCCEEEEEEEC AEGRTLEETAPPVIPRFSVMTSAESSPLEASPAPPATAGDSASTAVPVIAPETAYIMTNL CCCCCCHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH MESVVQSGTGQRARAVGRPVAGKTGTTNDMKDAWFVGYIPQLVAGVWVGYDQERSLGAGG HHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC SGGQAAAPIWTEFMRRAVAGIPSRDFETPPNVTFATINPRTGRLAREGSDGAVQECFIAG CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHEEEC TEPTAYDGESSEDGVP CCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10984043; 7901733 [H]