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The map label for this gene is 39998212

Identifier: 39998212

GI number: 39998212

Start: 3423529

End: 3424596

Strand: Reverse

Name: 39998212

Synonym: GSU3122

Alternate gene names: NA

Gene position: 3424596-3423529 (Counterclockwise)

Preceding gene: 39998213

Following gene: 39998209

Centisome position: 89.79

GC content: 59.36

Gene sequence:

>1068_bases
ATGGCATCCACATTGTTCAATAAAACCAGTTCCGCCAGGACCCGGTCATCTCTCTCGCTCGCGAGTGACCTGAAACGTCC
GGTCGAGGTGACAACAGGCGGACCGCTTGAGCTGGCCCGCGTCATGTGGGATTTCTTTTTCAACAAACCTGCAGACACGC
GCCCTTCCGGGAAAATCCCGGTACAGACAGTGATCGGAGCGCAGTTGATGAGTGCCCCGAACAACACGGTGTACCGTCTT
GGACACTCAACCGTCCTGATGAAGCTTAATGACGCATTCTGGATAACCGACCCAATGTTTTCGGACCGGGCATCACCCGT
ACGGTTTGCCGGGCCGGAACGGTTCCACCCGCCCCCCATCAGTATCGACGAGCTCCCGCCGATCAGGGCGGTAATCATCT
CCCACGACCATTACGACCATCTGGACCACGATTCCATCATGAAGCTGGCGGGAAAAACGGAGTATTTCCTGACGCCGCTC
GGGGTGGGGGACATCCTTGCCGACTGGGGTGTGCCGGCGGCAAAGGTGCGGCAACTGGACTGGTGGCAGGGAATCGACGT
CGGCGGTGTCCGCTTTGTTGCCACCCCTGCGCAACACTTCTCCGGACGCGGTTTCTTCGGCAAAAATCTTACCCAGTGGG
CTTCATGGGTAATCCTTGCCCCTGGCCGGCGCCTGTTCTTCAGTGGTGACACCGGCTATTTCGACGGCTTCAAGCAGATC
GGCGATCAATATGGCCCCTTTGACCTGACCTTGTTGGAAGCAGGTGCCTACAATGCACGCTGGCCGAACGTCCACATGCA
CCCGGAAGAGAGCATCCAGGCGCATCTCGACCTGAAAGGCAAGAGCCTGCTCCCGATCCACAACGGCACCTTTGATCTCT
CCATGCACCCCTGGCGGGAGCCTTTTGACAGAATAGCCGCCCTGGGCATTGCCCGGGGCATTCCGGTCTTAACTCCGCTG
ATGGGCGAACCGGTGAGCATGGACGAGGCCACGGGCGGCCTGCGCTGGTTGCAGCTGAAGCCAGAGAGGCAAAAACGGCT
AAACCCCGCCCGAGGGAGCAGGGTTTAG

Upstream 100 bases:

>100_bases
TGAAAGAACTCGGGCTGGATTTCATCTGATCCGATCAAGCAGGCGGGAACCGATGAAACGAATCATACTCTATACCCTGA
TCGCAGGAGTCGTCATCGTT

Downstream 100 bases:

>100_bases
CCGTTTGAAGCCGGGGAGGATATGGTGCGTCAGGTTGTGATGCTTAGCAGCGACGTTGATGTGGAAGAACTGCTGCTGTC
CGAGTCCGATGCTCCCTTCA

Product: metallo-beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MASTLFNKTSSARTRSSLSLASDLKRPVEVTTGGPLELARVMWDFFFNKPADTRPSGKIPVQTVIGAQLMSAPNNTVYRL
GHSTVLMKLNDAFWITDPMFSDRASPVRFAGPERFHPPPISIDELPPIRAVIISHDHYDHLDHDSIMKLAGKTEYFLTPL
GVGDILADWGVPAAKVRQLDWWQGIDVGGVRFVATPAQHFSGRGFFGKNLTQWASWVILAPGRRLFFSGDTGYFDGFKQI
GDQYGPFDLTLLEAGAYNARWPNVHMHPEESIQAHLDLKGKSLLPIHNGTFDLSMHPWREPFDRIAALGIARGIPVLTPL
MGEPVSMDEATGGLRWLQLKPERQKRLNPARGSRV

Sequences:

>Translated_355_residues
MASTLFNKTSSARTRSSLSLASDLKRPVEVTTGGPLELARVMWDFFFNKPADTRPSGKIPVQTVIGAQLMSAPNNTVYRL
GHSTVLMKLNDAFWITDPMFSDRASPVRFAGPERFHPPPISIDELPPIRAVIISHDHYDHLDHDSIMKLAGKTEYFLTPL
GVGDILADWGVPAAKVRQLDWWQGIDVGGVRFVATPAQHFSGRGFFGKNLTQWASWVILAPGRRLFFSGDTGYFDGFKQI
GDQYGPFDLTLLEAGAYNARWPNVHMHPEESIQAHLDLKGKSLLPIHNGTFDLSMHPWREPFDRIAALGIARGIPVLTPL
MGEPVSMDEATGGLRWLQLKPERQKRLNPARGSRV
>Mature_354_residues
ASTLFNKTSSARTRSSLSLASDLKRPVEVTTGGPLELARVMWDFFFNKPADTRPSGKIPVQTVIGAQLMSAPNNTVYRLG
HSTVLMKLNDAFWITDPMFSDRASPVRFAGPERFHPPPISIDELPPIRAVIISHDHYDHLDHDSIMKLAGKTEYFLTPLG
VGDILADWGVPAAKVRQLDWWQGIDVGGVRFVATPAQHFSGRGFFGKNLTQWASWVILAPGRRLFFSGDTGYFDGFKQIG
DQYGPFDLTLLEAGAYNARWPNVHMHPEESIQAHLDLKGKSLLPIHNGTFDLSMHPWREPFDRIAALGIARGIPVLTPLM
GEPVSMDEATGGLRWLQLKPERQKRLNPARGSRV

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=230, Percent_Identity=43.9130434782609, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI170932481, Length=230, Percent_Identity=43.9130434782609, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17543102, Length=280, Percent_Identity=35.7142857142857, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25148824, Length=280, Percent_Identity=35.7142857142857, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17543100, Length=280, Percent_Identity=35.7142857142857, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17543104, Length=280, Percent_Identity=33.5714285714286, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6325154, Length=261, Percent_Identity=31.8007662835249, Blast_Score=116, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39530; Mature: 39399

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTLFNKTSSARTRSSLSLASDLKRPVEVTTGGPLELARVMWDFFFNKPADTRPSGKIP
CCCCHHCCCCCHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
VQTVIGAQLMSAPNNTVYRLGHSTVLMKLNDAFWITDPMFSDRASPVRFAGPERFHPPPI
HHHHHHHHHHCCCCCCEEEECCCEEEEEECCEEEEECCCCCCCCCCEEECCCCCCCCCCC
SIDELPPIRAVIISHDHYDHLDHDSIMKLAGKTEYFLTPLGVGDILADWGVPAAKVRQLD
CCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHCCCCHHHHHHCH
WWQGIDVGGVRFVATPAQHFSGRGFFGKNLTQWASWVILAPGRRLFFSGDTGYFDGFKQI
HHCCCCCCCEEEEECCHHHCCCCCCCCCCHHHHHCEEEECCCCEEEEECCCCHHHHHHHH
GDQYGPFDLTLLEAGAYNARWPNVHMHPEESIQAHLDLKGKSLLPIHNGTFDLSMHPWRE
CCCCCCEEEEEEECCCCCCCCCCCEECCHHHHEEEEEECCCEEEEEECCEEEECCCCCCC
PFDRIAALGIARGIPVLTPLMGEPVSMDEATGGLRWLQLKPERQKRLNPARGSRV
HHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCCCCCC
>Mature Secondary Structure 
ASTLFNKTSSARTRSSLSLASDLKRPVEVTTGGPLELARVMWDFFFNKPADTRPSGKIP
CCCHHCCCCCHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
VQTVIGAQLMSAPNNTVYRLGHSTVLMKLNDAFWITDPMFSDRASPVRFAGPERFHPPPI
HHHHHHHHHHCCCCCCEEEECCCEEEEEECCEEEEECCCCCCCCCCEEECCCCCCCCCCC
SIDELPPIRAVIISHDHYDHLDHDSIMKLAGKTEYFLTPLGVGDILADWGVPAAKVRQLD
CCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHCCCCHHHHHHCH
WWQGIDVGGVRFVATPAQHFSGRGFFGKNLTQWASWVILAPGRRLFFSGDTGYFDGFKQI
HHCCCCCCCEEEEECCHHHCCCCCCCCCCHHHHHCEEEECCCCEEEEECCCCHHHHHHHH
GDQYGPFDLTLLEAGAYNARWPNVHMHPEESIQAHLDLKGKSLLPIHNGTFDLSMHPWRE
CCCCCCEEEEEEECCCCCCCCCCCEECCHHHHEEEEEECCCEEEEEECCEEEECCCCCCC
PFDRIAALGIARGIPVLTPLMGEPVSMDEATGGLRWLQLKPERQKRLNPARGSRV
HHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]