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The map label for this gene is baeS [H]

Identifier: 39998209

GI number: 39998209

Start: 3420871

End: 3422421

Strand: Reverse

Name: baeS [H]

Synonym: GSU3119

Alternate gene names: 39998209

Gene position: 3422421-3420871 (Counterclockwise)

Preceding gene: 39998212

Following gene: 39998208

Centisome position: 89.73

GC content: 65.12

Gene sequence:

>1551_bases
GTGGAAGAAATGAGGAAAAGTGCCGGGCGCTTGTCATACCGGTCTCTCTACCCCCGGTGGATGTGGTACAACATTCACGA
GAGCGTTTCGCCGGGCACAAGGACGAGGACCATGAAGATCGGCATTACCCATCGGCTGTTCCTGGCCATGCTGGCAGCCG
CCGTGATGGCGGTAATCAGCATGGTCGTCATCATGACGTGGAGTGTTGACCGCGGGTTTCTCCGCTATGTCAACGCCATG
GAGCAGCGTCAGATTGACCGGCTGGCAGCGGAGCTGGAAAAGCGATTCGCTGCTGCAGGAAACTGGGATTTCCTGCGCCG
TGAGCCGGCCATGCTGGCCAGACTCGTGGCGGAGTCGCTACCCGCACGGGAGGAAATGCCGTTCGAACCCGGGCCGCCCG
GGCCGCTCCCCGGCGATGGGATGCGGCCGCCTCCGCCGCCCGAACGCATGGTTCATCACCTGACGGAGCGTCTCCTCATT
CTCGACGCACGCCGGGAGCATGTGCTGCCCGTCGACTTTTCCGGCGACGTGGCGGAGCTGAAAGCCCTGCGTTACAAGGG
GGCGGTTGCGGGGTACCTGGGGCTCGCCCCCCGCCGCAAGCTCTCCGAGGCACACCAACTCCGGTTCATCCGGGAACAGA
AACTGGCCGTGGCCCTGGTGGCGGGAGTGGTGGTCTGTCTCGCGGCCGGCCTGTCGCTTCTGGTCGCGAAGCGGCTCGTG
CGCCCCATCCGGGATCTGGCCGGGGCCACCGGTCAGCTTGCGGCCGGCCGGTTCGACACCAGGATCCCCGTGGCGTCGTC
GGACGAACTGGGACACCTGGCCCGCGACTTCAATGCCCTGGCCCTCACCTTGGAGAAGAACGAGCAGGCACGGAGGCAGT
GGGTGGCGGACATTTCGCACGAGCTCCGTACTCCGCTTGCCGTGCTCCGGGGCGAAATAGAAGCGATCCAGGATGGCGTC
CGACAACCGTCGCCGGATTCCATCCGCTCCCTCCATGGGGAGGTCCTGCGCCTGAATCGGTTGGTGGACGATCTTTACCA
GCTTTCCCTCACCGACATCGGCGCGCTCGCCTACCGGAAAGAGCCGCTGGACTTGGGGAGGGTACTGGTCGGCGCACTGG
TCAGCTACCGTGCCGAATTCGCCGGCAAGGGGATTGCCGTCCGCGAGGAGATATCCGTCCGGCAGCCAATCACGGTGTTC
GGCGATGCCGAGCGATTGCAGCAACTCTTCGTCAACCTGCTGGACAATGTTCTCAAATACACCGATATCGGCGGCGAGTT
GCTCGTTCGGCTCACGTGCCATGACGGGGCAGTGACCGTCGACCTGCAGGATTCGGTGCCCGGGGTGCCGGAAGAAGCCC
TCGGGATGCTCTTCGAGCGGCTTTACCGGGTTGAGGGCTCCCGTAGTCGGGCCAGGGGCGGCGCGGGGCTCGGCCTGGCG
ATCTGCCGGAACATTGTCGAGGCTCACAACGGCACCATCACGGCCCGTTACTCGCCCCTGGGCGGGGTCTGGATTGCCGT
GACGCTGCCGGTCGGGGAGCATCAGCCATGA

Upstream 100 bases:

>100_bases
ACCAGCGCGATCATGCACAGCTGCTTTTTCATGGTGATTCTCCTTTCCTGTGTGATGTTGCCGTACTGTCCGAGTAATAG
CGCGGGAATGTGGCCGCAAT

Downstream 100 bases:

>100_bases
CCGGAACGATTCTCATTGTGGAGGACGAGGAGAAGATTGCCACCCTGCTGCGCGATTATCTGCGATTGGCGGGATTTGAC
GTCTGTTGTCTGGCGGGAGG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MEEMRKSAGRLSYRSLYPRWMWYNIHESVSPGTRTRTMKIGITHRLFLAMLAAAVMAVISMVVIMTWSVDRGFLRYVNAM
EQRQIDRLAAELEKRFAAAGNWDFLRREPAMLARLVAESLPAREEMPFEPGPPGPLPGDGMRPPPPPERMVHHLTERLLI
LDARREHVLPVDFSGDVAELKALRYKGAVAGYLGLAPRRKLSEAHQLRFIREQKLAVALVAGVVVCLAAGLSLLVAKRLV
RPIRDLAGATGQLAAGRFDTRIPVASSDELGHLARDFNALALTLEKNEQARRQWVADISHELRTPLAVLRGEIEAIQDGV
RQPSPDSIRSLHGEVLRLNRLVDDLYQLSLTDIGALAYRKEPLDLGRVLVGALVSYRAEFAGKGIAVREEISVRQPITVF
GDAERLQQLFVNLLDNVLKYTDIGGELLVRLTCHDGAVTVDLQDSVPGVPEEALGMLFERLYRVEGSRSRARGGAGLGLA
ICRNIVEAHNGTITARYSPLGGVWIAVTLPVGEHQP

Sequences:

>Translated_516_residues
MEEMRKSAGRLSYRSLYPRWMWYNIHESVSPGTRTRTMKIGITHRLFLAMLAAAVMAVISMVVIMTWSVDRGFLRYVNAM
EQRQIDRLAAELEKRFAAAGNWDFLRREPAMLARLVAESLPAREEMPFEPGPPGPLPGDGMRPPPPPERMVHHLTERLLI
LDARREHVLPVDFSGDVAELKALRYKGAVAGYLGLAPRRKLSEAHQLRFIREQKLAVALVAGVVVCLAAGLSLLVAKRLV
RPIRDLAGATGQLAAGRFDTRIPVASSDELGHLARDFNALALTLEKNEQARRQWVADISHELRTPLAVLRGEIEAIQDGV
RQPSPDSIRSLHGEVLRLNRLVDDLYQLSLTDIGALAYRKEPLDLGRVLVGALVSYRAEFAGKGIAVREEISVRQPITVF
GDAERLQQLFVNLLDNVLKYTDIGGELLVRLTCHDGAVTVDLQDSVPGVPEEALGMLFERLYRVEGSRSRARGGAGLGLA
ICRNIVEAHNGTITARYSPLGGVWIAVTLPVGEHQP
>Mature_516_residues
MEEMRKSAGRLSYRSLYPRWMWYNIHESVSPGTRTRTMKIGITHRLFLAMLAAAVMAVISMVVIMTWSVDRGFLRYVNAM
EQRQIDRLAAELEKRFAAAGNWDFLRREPAMLARLVAESLPAREEMPFEPGPPGPLPGDGMRPPPPPERMVHHLTERLLI
LDARREHVLPVDFSGDVAELKALRYKGAVAGYLGLAPRRKLSEAHQLRFIREQKLAVALVAGVVVCLAAGLSLLVAKRLV
RPIRDLAGATGQLAAGRFDTRIPVASSDELGHLARDFNALALTLEKNEQARRQWVADISHELRTPLAVLRGEIEAIQDGV
RQPSPDSIRSLHGEVLRLNRLVDDLYQLSLTDIGALAYRKEPLDLGRVLVGALVSYRAEFAGKGIAVREEISVRQPITVF
GDAERLQQLFVNLLDNVLKYTDIGGELLVRLTCHDGAVTVDLQDSVPGVPEEALGMLFERLYRVEGSRSRARGGAGLGLA
ICRNIVEAHNGTITARYSPLGGVWIAVTLPVGEHQP

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=475, Percent_Identity=44, Blast_Score=345, Evalue=3e-96,
Organism=Escherichia coli, GI1786783, Length=315, Percent_Identity=30.7936507936508, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=33.6244541484716, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1789149, Length=356, Percent_Identity=24.7191011235955, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=27.7372262773723, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786600, Length=265, Percent_Identity=29.0566037735849, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787894, Length=324, Percent_Identity=26.2345679012346, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=25.9574468085106, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=27.0903010033445, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081816, Length=230, Percent_Identity=27.8260869565217, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788279, Length=340, Percent_Identity=26.1764705882353, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788713, Length=255, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=24.8908296943231, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=298, Percent_Identity=26.1744966442953, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=310, Percent_Identity=24.5161290322581, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=319, Percent_Identity=26.0188087774295, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789403, Length=298, Percent_Identity=27.8523489932886, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=26.6968325791855, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57120; Mature: 57120

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEMRKSAGRLSYRSLYPRWMWYNIHESVSPGTRTRTMKIGITHRLFLAMLAAAVMAVIS
CCHHHHHHCCCHHHHHCCHHEEEEHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHH
MVVIMTWSVDRGFLRYVNAMEQRQIDRLAAELEKRFAAAGNWDFLRREPAMLARLVAESL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHC
PAREEMPFEPGPPGPLPGDGMRPPPPPERMVHHLTERLLILDARREHVLPVDFSGDVAEL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHH
KALRYKGAVAGYLGLAPRRKLSEAHQLRFIREQKLAVALVAGVVVCLAAGLSLLVAKRLV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPIRDLAGATGQLAAGRFDTRIPVASSDELGHLARDFNALALTLEKNEQARRQWVADISH
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHH
ELRTPLAVLRGEIEAIQDGVRQPSPDSIRSLHGEVLRLNRLVDDLYQLSLTDIGALAYRK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPLDLGRVLVGALVSYRAEFAGKGIAVREEISVRQPITVFGDAERLQQLFVNLLDNVLKY
CCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHH
TDIGGELLVRLTCHDGAVTVDLQDSVPGVPEEALGMLFERLYRVEGSRSRARGGAGLGLA
HCCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCHHHH
ICRNIVEAHNGTITARYSPLGGVWIAVTLPVGEHQP
HHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MEEMRKSAGRLSYRSLYPRWMWYNIHESVSPGTRTRTMKIGITHRLFLAMLAAAVMAVIS
CCHHHHHHCCCHHHHHCCHHEEEEHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHH
MVVIMTWSVDRGFLRYVNAMEQRQIDRLAAELEKRFAAAGNWDFLRREPAMLARLVAESL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHC
PAREEMPFEPGPPGPLPGDGMRPPPPPERMVHHLTERLLILDARREHVLPVDFSGDVAEL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHH
KALRYKGAVAGYLGLAPRRKLSEAHQLRFIREQKLAVALVAGVVVCLAAGLSLLVAKRLV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPIRDLAGATGQLAAGRFDTRIPVASSDELGHLARDFNALALTLEKNEQARRQWVADISH
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHH
ELRTPLAVLRGEIEAIQDGVRQPSPDSIRSLHGEVLRLNRLVDDLYQLSLTDIGALAYRK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPLDLGRVLVGALVSYRAEFAGKGIAVREEISVRQPITVFGDAERLQQLFVNLLDNVLKY
CCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHH
TDIGGELLVRLTCHDGAVTVDLQDSVPGVPEEALGMLFERLYRVEGSRSRARGGAGLGLA
HCCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCHHHH
ICRNIVEAHNGTITARYSPLGGVWIAVTLPVGEHQP
HHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]