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The map label for this gene is plsC [H]

Identifier: 39998206

GI number: 39998206

Start: 3418703

End: 3419407

Strand: Reverse

Name: plsC [H]

Synonym: GSU3116

Alternate gene names: 39998206

Gene position: 3419407-3418703 (Counterclockwise)

Preceding gene: 39998208

Following gene: 39998205

Centisome position: 89.65

GC content: 64.68

Gene sequence:

>705_bases
ATGCTTAACGGACTGATTTACCTCGCCTTTTTTATTCCGCTCTCCGGCTTCTTCAGCTTTGCGGCCCTTGTGGGGAGCCT
GGTGGATGCCAGTGGCGGCTTTGCCCACCGCTGTGCCCTCGCCTGGAGCCGGATCGGCCTCATGATGGCCGGGGTGCGCC
TCGACGTGAGCGGAACCGAGAATGTGCCGGCGGGAGAGCCGGTCATCTTCATGGGGAACCACCAGGGAAACTTCGACATT
CTCGTCCTGTCGCGGGCCATTCCGCGCCGCTTCTCCTGGCTCGCCAAGGAGGAGCTCTTCCGTATCCCCCTGTTCGGCGC
CGCCATGCAACGGGCAGGCTACATCCCCGTTGACCGGAGCGACGGCCGTAAGGCCCTGCGGAGTCTCGATGCCGCAGCAA
AGCGGATCAGGGCAGGGGCCAGCGTCATCGTCTTCCCCGAAGGGACCCGCACCGCCGACGGATCGCTCCTTCCGTTCAAA
AAAGGGGGATTTGTCCTGGCCGAACGGGCCGGGGTGCCCATTATTCCGTTCACCATCAACGGGAGCATGCAGGTGAATCC
GCGCAACACCGTGAAGCTTGTGCGGGGTGCCAGGATCGCCGTCCGGTTCGGGACCCCGATTCCGACCTCCGGTGCCGGCG
CCCTCAAGGGGACGCCGCTCATGGAACAGGTACGGTCCGCCATTCAGTCGGGGCTGGAGGGGTAG

Upstream 100 bases:

>100_bases
AGGTTCAAAGGGATTTCGAGAGGTTCCGCCGGTCGTATATTGGTTTGACTCCCCTGCCAAAAAGCAGTAAGGTTAATCGG
ATATTTCCCCGGAGCCACCA

Downstream 100 bases:

>100_bases
GATGCTCGCCTTGTCTTTTGTTCTCATCGGTGGCGGCCTCCTGGTGACGGCGTGGGGGCTTCCGGCGGCCCACCGGCTCC
GGCGACCCTGGGGTGCGGTG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLNGLIYLAFFIPLSGFFSFAALVGSLVDASGGFAHRCALAWSRIGLMMAGVRLDVSGTENVPAGEPVIFMGNHQGNFDI
LVLSRAIPRRFSWLAKEELFRIPLFGAAMQRAGYIPVDRSDGRKALRSLDAAAKRIRAGASVIVFPEGTRTADGSLLPFK
KGGFVLAERAGVPIIPFTINGSMQVNPRNTVKLVRGARIAVRFGTPIPTSGAGALKGTPLMEQVRSAIQSGLEG

Sequences:

>Translated_234_residues
MLNGLIYLAFFIPLSGFFSFAALVGSLVDASGGFAHRCALAWSRIGLMMAGVRLDVSGTENVPAGEPVIFMGNHQGNFDI
LVLSRAIPRRFSWLAKEELFRIPLFGAAMQRAGYIPVDRSDGRKALRSLDAAAKRIRAGASVIVFPEGTRTADGSLLPFK
KGGFVLAERAGVPIIPFTINGSMQVNPRNTVKLVRGARIAVRFGTPIPTSGAGALKGTPLMEQVRSAIQSGLEG
>Mature_234_residues
MLNGLIYLAFFIPLSGFFSFAALVGSLVDASGGFAHRCALAWSRIGLMMAGVRLDVSGTENVPAGEPVIFMGNHQGNFDI
LVLSRAIPRRFSWLAKEELFRIPLFGAAMQRAGYIPVDRSDGRKALRSLDAAAKRIRAGASVIVFPEGTRTADGSLLPFK
KGGFVLAERAGVPIIPFTINGSMQVNPRNTVKLVRGARIAVRFGTPIPTSGAGALKGTPLMEQVRSAIQSGLEG

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=181, Percent_Identity=32.5966850828729, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI15100175, Length=181, Percent_Identity=32.5966850828729, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI6041665, Length=181, Percent_Identity=30.3867403314917, Blast_Score=91, Evalue=6e-19,
Organism=Escherichia coli, GI1789395, Length=183, Percent_Identity=30.0546448087432, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17564032, Length=224, Percent_Identity=26.3392857142857, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17568319, Length=127, Percent_Identity=35.4330708661417, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320151, Length=224, Percent_Identity=32.1428571428571, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24641614, Length=231, Percent_Identity=30.7359307359307, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24641612, Length=231, Percent_Identity=30.7359307359307, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281364648, Length=135, Percent_Identity=35.5555555555556, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24582856, Length=135, Percent_Identity=35.5555555555556, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24582854, Length=135, Percent_Identity=35.5555555555556, Blast_Score=87, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 24915; Mature: 24915

Theoretical pI: Translated: 11.57; Mature: 11.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNGLIYLAFFIPLSGFFSFAALVGSLVDASGGFAHRCALAWSRIGLMMAGVRLDVSGTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCC
NVPAGEPVIFMGNHQGNFDILVLSRAIPRRFSWLAKEELFRIPLFGAAMQRAGYIPVDRS
CCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCC
DGRKALRSLDAAAKRIRAGASVIVFPEGTRTADGSLLPFKKGGFVLAERAGVPIIPFTIN
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEECCCCEEEEECCCCEEEEEEEC
GSMQVNPRNTVKLVRGARIAVRFGTPIPTSGAGALKGTPLMEQVRSAIQSGLEG
CEEEECCCHHEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLNGLIYLAFFIPLSGFFSFAALVGSLVDASGGFAHRCALAWSRIGLMMAGVRLDVSGTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCC
NVPAGEPVIFMGNHQGNFDILVLSRAIPRRFSWLAKEELFRIPLFGAAMQRAGYIPVDRS
CCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCC
DGRKALRSLDAAAKRIRAGASVIVFPEGTRTADGSLLPFKKGGFVLAERAGVPIIPFTIN
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEECCCCEEEEECCCCEEEEEEEC
GSMQVNPRNTVKLVRGARIAVRFGTPIPTSGAGALKGTPLMEQVRSAIQSGLEG
CEEEECCCHHEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]