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The map label for this gene is murG

Identifier: 39998160

GI number: 39998160

Start: 3375076

End: 3376170

Strand: Reverse

Name: murG

Synonym: GSU3069

Alternate gene names: 39998160

Gene position: 3376170-3375076 (Counterclockwise)

Preceding gene: 308513336

Following gene: 39998159

Centisome position: 88.52

GC content: 63.65

Gene sequence:

>1095_bases
ATGAAGCTGCTGATAGCCGGAGGGGGAACGGGCGGGCATCTCTTCCCGGGCATAGCGGTGGCCGAGGAGTTCCTCGCCCG
CGACAAACAGAATGAAGTCCTCTTCGTGGGAACCTGGAAAGGGATCGAGGCGAGGGTGCTGCCGAAAACGGGGTACCGGC
TCGAATGCATCACCGCAGCCGGTATTCGGGGCAAGGGAAGCCTGGCCCGGGCCAAGGGGCTTGCCAAATTCCTCTACGGC
TACGCCCAGTCGCGCAAGATACTGAAGGAGTTCAGGCCGGACCTGGTGCTCGGCGTCGGCGGATACGCTTCGGCGCCCAC
CCTGATGGCGGCGCGGGGAATGCAGATCCCGCGCTTCATCCACGAGCAGAACGCTATCCCGGGCTTCACCAACCGGATGT
TGGCCAAGGTGGCAGACAAGATATTCATCTCTCTTGAGGAGTCGCGGACGTATTTCCCCGAGGACAAGACGCTCCTGACC
GGCAATCCGCTTCGCCGCCAGATACTGGAGCAGGTTGCCCTGGCGGAGTCCCGGGAGAGAGGCGATGACGCCTTCCATCT
CCTGGTCTTCGGCGGGAGTGCCGGCGCTCACCGGATCAACCTGACCATGGGCGAGGCTCTGCCCTCCCTGAAGGAGGCGA
AGGGGAGACTGCGGATCACCCACCAGACCGGTGAGAACGATCTGGAGGATGTCACCGCCGCCTATGAAGAGCAAGGCTTT
ACGGCTGATGTGGTGGCCTTCATCGACTCCATGGCCGATGCCTATCGCTGGGCCGACCTGATCGTCTGCCGGGCAGGGGC
CACCACCCTCGCCGAGGTAACCGCCTGCGGCAAGCCCTGCATCTTCATCCCTTACCCCCATGCCGTGGACGACCACCAGC
GCCGCAACGCCGAATCGCTTCTCAAGCGGGGAGCCGGGTTCGTCATAATCGAGCAGGAACTTTCAGGCGAGGTGCTGGCA
CAGGCGATCCGCGATCTCATGGACGACCCGGCGCGGCTCAAGGCTGTCGGCGAGGCGGCCCAGGAGCTTGCCCGGCTTGA
TGCGGCCCAGGCCATCGTCGACGAGATGGTGGCAAGCACAAGGAAAGAAGAGTAA

Upstream 100 bases:

>100_bases
TGGCGCTTCCCTTTATCAGCTACGGAGGAAGTTCATTGATCGTGACACTGTTCGCAGTGGGTATCCTTCTCAATATCTCG
ACGCGGCTCAAGGGGGCACC

Downstream 100 bases:

>100_bases
CCATGTACGGTAAAATAGAGAAAATTCACTTCGTCGGCATCGGCGGCATCGGCATGAGCGGCATTGCCGAGGTTCTCCTC
AACCTGGGATATAAGGTGTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKLLIAGGGTGGHLFPGIAVAEEFLARDKQNEVLFVGTWKGIEARVLPKTGYRLECITAAGIRGKGSLARAKGLAKFLYG
YAQSRKILKEFRPDLVLGVGGYASAPTLMAARGMQIPRFIHEQNAIPGFTNRMLAKVADKIFISLEESRTYFPEDKTLLT
GNPLRRQILEQVALAESRERGDDAFHLLVFGGSAGAHRINLTMGEALPSLKEAKGRLRITHQTGENDLEDVTAAYEEQGF
TADVVAFIDSMADAYRWADLIVCRAGATTLAEVTACGKPCIFIPYPHAVDDHQRRNAESLLKRGAGFVIIEQELSGEVLA
QAIRDLMDDPARLKAVGEAAQELARLDAAQAIVDEMVASTRKEE

Sequences:

>Translated_364_residues
MKLLIAGGGTGGHLFPGIAVAEEFLARDKQNEVLFVGTWKGIEARVLPKTGYRLECITAAGIRGKGSLARAKGLAKFLYG
YAQSRKILKEFRPDLVLGVGGYASAPTLMAARGMQIPRFIHEQNAIPGFTNRMLAKVADKIFISLEESRTYFPEDKTLLT
GNPLRRQILEQVALAESRERGDDAFHLLVFGGSAGAHRINLTMGEALPSLKEAKGRLRITHQTGENDLEDVTAAYEEQGF
TADVVAFIDSMADAYRWADLIVCRAGATTLAEVTACGKPCIFIPYPHAVDDHQRRNAESLLKRGAGFVIIEQELSGEVLA
QAIRDLMDDPARLKAVGEAAQELARLDAAQAIVDEMVASTRKEE
>Mature_364_residues
MKLLIAGGGTGGHLFPGIAVAEEFLARDKQNEVLFVGTWKGIEARVLPKTGYRLECITAAGIRGKGSLARAKGLAKFLYG
YAQSRKILKEFRPDLVLGVGGYASAPTLMAARGMQIPRFIHEQNAIPGFTNRMLAKVADKIFISLEESRTYFPEDKTLLT
GNPLRRQILEQVALAESRERGDDAFHLLVFGGSAGAHRINLTMGEALPSLKEAKGRLRITHQTGENDLEDVTAAYEEQGF
TADVVAFIDSMADAYRWADLIVCRAGATTLAEVTACGKPCIFIPYPHAVDDHQRRNAESLLKRGAGFVIIEQELSGEVLA
QAIRDLMDDPARLKAVGEAAQELARLDAAQAIVDEMVASTRKEE

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=357, Percent_Identity=37.2549019607843, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_GEOSL (Q748D6)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_954111.1
- ProteinModelPortal:   Q748D6
- SMR:   Q748D6
- GeneID:   2686309
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU3069
- NMPDR:   fig|243231.1.peg.3049
- TIGR:   GSU3069
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   GSUL243231:GSU_3069-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39639; Mature: 39639

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLIAGGGTGGHLFPGIAVAEEFLARDKQNEVLFVGTWKGIEARVLPKTGYRLECITAA
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCEEEEEEEC
GIRGKGSLARAKGLAKFLYGYAQSRKILKEFRPDLVLGVGGYASAPTLMAARGMQIPRFI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHCCCCCHHHH
HEQNAIPGFTNRMLAKVADKIFISLEESRTYFPEDKTLLTGNPLRRQILEQVALAESRER
HHCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCC
GDDAFHLLVFGGSAGAHRINLTMGEALPSLKEAKGRLRITHQTGENDLEDVTAAYEEQGF
CCCEEEEEEEECCCCCEEEEEEHHHHCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCC
TADVVAFIDSMADAYRWADLIVCRAGATTLAEVTACGKPCIFIPYPHAVDDHQRRNAESL
HHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCEEEECCCCCCCHHHHCCHHHH
LKRGAGFVIIEQELSGEVLAQAIRDLMDDPARLKAVGEAAQELARLDAAQAIVDEMVAST
HHCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKEE
CCCC
>Mature Secondary Structure
MKLLIAGGGTGGHLFPGIAVAEEFLARDKQNEVLFVGTWKGIEARVLPKTGYRLECITAA
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCEEEEEEEC
GIRGKGSLARAKGLAKFLYGYAQSRKILKEFRPDLVLGVGGYASAPTLMAARGMQIPRFI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHCCCCCHHHH
HEQNAIPGFTNRMLAKVADKIFISLEESRTYFPEDKTLLTGNPLRRQILEQVALAESRER
HHCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCC
GDDAFHLLVFGGSAGAHRINLTMGEALPSLKEAKGRLRITHQTGENDLEDVTAAYEEQGF
CCCEEEEEEEECCCCCEEEEEEHHHHCCHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCC
TADVVAFIDSMADAYRWADLIVCRAGATTLAEVTACGKPCIFIPYPHAVDDHQRRNAESL
HHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCEEEECCCCCCCHHHHCCHHHH
LKRGAGFVIIEQELSGEVLAQAIRDLMDDPARLKAVGEAAQELARLDAAQAIVDEMVAST
HHCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKEE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA