Click here to switch to the map view.

The map label for this gene is cph1 [H]

Identifier: 39998082

GI number: 39998082

Start: 3282674

End: 3284707

Strand: Reverse

Name: cph1 [H]

Synonym: GSU2991

Alternate gene names: 39998082

Gene position: 3284707-3282674 (Counterclockwise)

Preceding gene: 308513333

Following gene: 39998081

Centisome position: 86.12

GC content: 63.52

Gene sequence:

>2034_bases
GTGACCATAAAACGGAAAGTGCAAATCGTCATCATCCTGATCGCAATACATGTTGCAGTGTTCGTGGGATACCTGTTTCA
CTCGTCGGCCCAGGTCCATACGCGGGTGCGCCATCTCATCCCGGCGGTCGAATACCTGAGGGGCATTGCCCTGGCCCGGG
CCGGCATGATTCAGCAGATGAAGGAGGTGGTCGATTATCTGGCCATCTCCGATCCTGCCGCCCGGGATGAATTCCGCAAG
GGCGGCCAGTTGGCCGATGAGTCCTTTTCCGTCTGGATCGATGCCATCAAGGCGCAGAGGGCGCTGGGCGTTGCCGGCGA
GGACGACGATCTTGAACTGGTCCAGGAGGTGCAGACCCGCTATGCCTCATGGGTTCGCACGGCCGAATGGTTTTTTGAGC
TCCAGGACGCGGGCCGCGGCGATGAGGCGATGGCGCTGTTCCGCGATCGGCTTGAGCCCTATTTCGATCGGGAGGTGCTC
CTGCCCGTGGACAAGGCCCTCGATGACGGAGCGGTGGAGGTGCACGTCGCCTTTCACAATCTATTAATGGCCGTGGGGCG
GATCCCCTGGATGTCCGCGGAGGGAGTCCGGAACATCGAGCGGGGCGAAGCGGCCCTGGACGGCTTTCTTGCCGCCAACC
ACCTGCTGTTCGAGGTGACCGGGCAGCTCAAGGAGCTGATGAAGTATCTGCTCAACCAGCGCCAGGGCATCGAGACCGAT
CTTTCGCGGCTGGACTGGCAGGCCGGCCATGCCCTGGAGAATTTCCGGCAGCAGATGTGGAGCCTGGCACGCCAGGGTGA
CCCGACGGCATTGAAGGACGCTGAGACCGTTACACGGAGCTTCCAGGAGCTGACCGGGCTCATGCATCAGGCCGTGGCGC
TCAAAAGGGCTGGGCGCGGGCATGAGGCGGTGGCTCTGGCCAACTCCCGCATGGAGGCGGTTCTCTACAAGACGCTCATG
CCCATCATTTCCCGATCGCTGGATTCGGGCAGTGCCCAGATGCTCACCCTGACCGCCGCGGCCCGCTGGCAGGGCGTTCT
TGCCGTTTCGCTCTTCCTGGTGATGGCGGTGAGCCTCATCCTCGGAACGAGCCGGTCCGTTCTCCGGGCCCTGGATTCGC
TCATGGCCGGTACCTCGGCCATTGCCGAAGGGGATTTCTCCCACCGGCTCGATGCCCGGCGTTCGGACGAGCTGGGCGCC
CTTGCCGTCTCCTTCAACACCATGGTGGAGCGCCTCCAGAAATCCCGACGCGACCTGGACTCGTTCGCCCGGCTTCTGGA
GCAGCGAGTGTACGACCGGACCGTCCAGCTGGAAGAGGCGAACGAGGATCTGAGGCAATTCAGTTCATCCCTGAGCCATG
ATATCCGAACGCCCCTGTCGAGCATCGCCGGCTACGTGCAACTGGCGCGCGCCGAATGCGACGGCACCGAGAGCGAGCTG
CTGCCGGATTTATTCACGGCCATTGAGCTTGCCACGGCAAGGATGAACGCCCTCGTCGACGCGCAGCTCGCCCTTGCCCG
CGCCACCTGCAAGGAGTTGAACCTCGAGCCGGTGGACATGGCGGAAATAGGTCAGGCCGTGATAGATAACCTCCAATTCG
CCGAGCCGCAACGGAAGGTAGGCTTCCAGGTGGCGGGCGATCTGACTGTGGATGGGGACATGGACCTGCTGGGCCTTGCG
GTGGAGAACCTGCTCAGCAACGCGTGGAAGTACACGGCCATCAGGGATGAAGCCGTCATCGAGTTCGGGTCCCGGGACGA
GGGGGATCGGCGGATTTACTTTGTCCGCGATAACGGTGCGGGATTCGATCCGGAGGAGATCAATCGTCTCTTCCGACCCT
TCAGCCGGCTGCATGCAGCCGAGCAGTTCCCGGGGACCGGCGTCGGCCTCGCCACCGTGGCTCGGGTGATCCGCCGGCAC
GGTGGCCGCACCTGGGCCGAAGGTGCCGTGGACCGGGGTGCCACGTTCTTCTTTACGCTCAACGAAACGCCGCTGCCGGT
GGTTGTGCCGCCACAGCCGGAGGAGAGCGCGTGA

Upstream 100 bases:

>100_bases
CGCGCACCTGGAGAAGCATCTGAACATTGATCGCATGCTGGAACTCTGCGGCCTCGGCGGGATGTTGCCGGAGTAGTGGT
CTTTTCAGAGGAGATTCCCC

Downstream 100 bases:

>100_bases
CCGGCCCTGACCGGGTGGCCCTGCTGGTCCTTGCCGCCCTTGTTCTCGACTGGCTGCTGGGCGATCCTCGCTGGCTCCCC
CATCCGGTGGTGGCCGTGGG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MTIKRKVQIVIILIAIHVAVFVGYLFHSSAQVHTRVRHLIPAVEYLRGIALARAGMIQQMKEVVDYLAISDPAARDEFRK
GGQLADESFSVWIDAIKAQRALGVAGEDDDLELVQEVQTRYASWVRTAEWFFELQDAGRGDEAMALFRDRLEPYFDREVL
LPVDKALDDGAVEVHVAFHNLLMAVGRIPWMSAEGVRNIERGEAALDGFLAANHLLFEVTGQLKELMKYLLNQRQGIETD
LSRLDWQAGHALENFRQQMWSLARQGDPTALKDAETVTRSFQELTGLMHQAVALKRAGRGHEAVALANSRMEAVLYKTLM
PIISRSLDSGSAQMLTLTAAARWQGVLAVSLFLVMAVSLILGTSRSVLRALDSLMAGTSAIAEGDFSHRLDARRSDELGA
LAVSFNTMVERLQKSRRDLDSFARLLEQRVYDRTVQLEEANEDLRQFSSSLSHDIRTPLSSIAGYVQLARAECDGTESEL
LPDLFTAIELATARMNALVDAQLALARATCKELNLEPVDMAEIGQAVIDNLQFAEPQRKVGFQVAGDLTVDGDMDLLGLA
VENLLSNAWKYTAIRDEAVIEFGSRDEGDRRIYFVRDNGAGFDPEEINRLFRPFSRLHAAEQFPGTGVGLATVARVIRRH
GGRTWAEGAVDRGATFFFTLNETPLPVVVPPQPEESA

Sequences:

>Translated_677_residues
MTIKRKVQIVIILIAIHVAVFVGYLFHSSAQVHTRVRHLIPAVEYLRGIALARAGMIQQMKEVVDYLAISDPAARDEFRK
GGQLADESFSVWIDAIKAQRALGVAGEDDDLELVQEVQTRYASWVRTAEWFFELQDAGRGDEAMALFRDRLEPYFDREVL
LPVDKALDDGAVEVHVAFHNLLMAVGRIPWMSAEGVRNIERGEAALDGFLAANHLLFEVTGQLKELMKYLLNQRQGIETD
LSRLDWQAGHALENFRQQMWSLARQGDPTALKDAETVTRSFQELTGLMHQAVALKRAGRGHEAVALANSRMEAVLYKTLM
PIISRSLDSGSAQMLTLTAAARWQGVLAVSLFLVMAVSLILGTSRSVLRALDSLMAGTSAIAEGDFSHRLDARRSDELGA
LAVSFNTMVERLQKSRRDLDSFARLLEQRVYDRTVQLEEANEDLRQFSSSLSHDIRTPLSSIAGYVQLARAECDGTESEL
LPDLFTAIELATARMNALVDAQLALARATCKELNLEPVDMAEIGQAVIDNLQFAEPQRKVGFQVAGDLTVDGDMDLLGLA
VENLLSNAWKYTAIRDEAVIEFGSRDEGDRRIYFVRDNGAGFDPEEINRLFRPFSRLHAAEQFPGTGVGLATVARVIRRH
GGRTWAEGAVDRGATFFFTLNETPLPVVVPPQPEESA
>Mature_676_residues
TIKRKVQIVIILIAIHVAVFVGYLFHSSAQVHTRVRHLIPAVEYLRGIALARAGMIQQMKEVVDYLAISDPAARDEFRKG
GQLADESFSVWIDAIKAQRALGVAGEDDDLELVQEVQTRYASWVRTAEWFFELQDAGRGDEAMALFRDRLEPYFDREVLL
PVDKALDDGAVEVHVAFHNLLMAVGRIPWMSAEGVRNIERGEAALDGFLAANHLLFEVTGQLKELMKYLLNQRQGIETDL
SRLDWQAGHALENFRQQMWSLARQGDPTALKDAETVTRSFQELTGLMHQAVALKRAGRGHEAVALANSRMEAVLYKTLMP
IISRSLDSGSAQMLTLTAAARWQGVLAVSLFLVMAVSLILGTSRSVLRALDSLMAGTSAIAEGDFSHRLDARRSDELGAL
AVSFNTMVERLQKSRRDLDSFARLLEQRVYDRTVQLEEANEDLRQFSSSLSHDIRTPLSSIAGYVQLARAECDGTESELL
PDLFTAIELATARMNALVDAQLALARATCKELNLEPVDMAEIGQAVIDNLQFAEPQRKVGFQVAGDLTVDGDMDLLGLAV
ENLLSNAWKYTAIRDEAVIEFGSRDEGDRRIYFVRDNGAGFDPEEINRLFRPFSRLHAAEQFPGTGVGLATVARVIRRHG
GRTWAEGAVDRGATFFFTLNETPLPVVVPPQPEESA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=319, Percent_Identity=29.153605015674, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=291, Percent_Identity=27.4914089347079, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=29.7413793103448, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI87081816, Length=376, Percent_Identity=27.3936170212766, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=28.1385281385281, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=258, Percent_Identity=29.4573643410853, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=30.0448430493274, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI48994928, Length=257, Percent_Identity=28.0155642023346, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=197, Percent_Identity=30.4568527918782, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789149, Length=343, Percent_Identity=22.7405247813411, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790861, Length=235, Percent_Identity=29.7872340425532, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=25.9109311740891, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790551, Length=316, Percent_Identity=24.0506329113924, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=26.7543859649123, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=26.6968325791855, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75119; Mature: 74987

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKRKVQIVIILIAIHVAVFVGYLFHSSAQVHTRVRHLIPAVEYLRGIALARAGMIQQM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEVVDYLAISDPAARDEFRKGGQLADESFSVWIDAIKAQRALGVAGEDDDLELVQEVQTR
HHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YASWVRTAEWFFELQDAGRGDEAMALFRDRLEPYFDREVLLPVDKALDDGAVEVHVAFHN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCEECCHHHCCCCCCEEEHHHHHH
LLMAVGRIPWMSAEGVRNIERGEAALDGFLAANHLLFEVTGQLKELMKYLLNQRQGIETD
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LSRLDWQAGHALENFRQQMWSLARQGDPTALKDAETVTRSFQELTGLMHQAVALKRAGRG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HEAVALANSRMEAVLYKTLMPIISRSLDSGSAQMLTLTAAARWQGVLAVSLFLVMAVSLI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
LGTSRSVLRALDSLMAGTSAIAEGDFSHRLDARRSDELGALAVSFNTMVERLQKSRRDLD
HCCCHHHHHHHHHHHHCCHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SFARLLEQRVYDRTVQLEEANEDLRQFSSSLSHDIRTPLSSIAGYVQLARAECDGTESEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LPDLFTAIELATARMNALVDAQLALARATCKELNLEPVDMAEIGQAVIDNLQFAEPQRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHC
GFQVAGDLTVDGDMDLLGLAVENLLSNAWKYTAIRDEAVIEFGSRDEGDRRIYFVRDNGA
CCEEECCEEECCCHHHHHHHHHHHHHCCHHHHEECHHHHHCCCCCCCCCCEEEEEECCCC
GFDPEEINRLFRPFSRLHAAEQFPGTGVGLATVARVIRRHGGRTWAEGAVDRGATFFFTL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEE
NETPLPVVVPPQPEESA
CCCCCEEEECCCCCCCC
>Mature Secondary Structure 
TIKRKVQIVIILIAIHVAVFVGYLFHSSAQVHTRVRHLIPAVEYLRGIALARAGMIQQM
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEVVDYLAISDPAARDEFRKGGQLADESFSVWIDAIKAQRALGVAGEDDDLELVQEVQTR
HHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YASWVRTAEWFFELQDAGRGDEAMALFRDRLEPYFDREVLLPVDKALDDGAVEVHVAFHN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCEECCHHHCCCCCCEEEHHHHHH
LLMAVGRIPWMSAEGVRNIERGEAALDGFLAANHLLFEVTGQLKELMKYLLNQRQGIETD
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LSRLDWQAGHALENFRQQMWSLARQGDPTALKDAETVTRSFQELTGLMHQAVALKRAGRG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HEAVALANSRMEAVLYKTLMPIISRSLDSGSAQMLTLTAAARWQGVLAVSLFLVMAVSLI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
LGTSRSVLRALDSLMAGTSAIAEGDFSHRLDARRSDELGALAVSFNTMVERLQKSRRDLD
HCCCHHHHHHHHHHHHCCHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SFARLLEQRVYDRTVQLEEANEDLRQFSSSLSHDIRTPLSSIAGYVQLARAECDGTESEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LPDLFTAIELATARMNALVDAQLALARATCKELNLEPVDMAEIGQAVIDNLQFAEPQRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHC
GFQVAGDLTVDGDMDLLGLAVENLLSNAWKYTAIRDEAVIEFGSRDEGDRRIYFVRDNGA
CCEEECCEEECCCHHHHHHHHHHHHHCCHHHHEECHHHHHCCCCCCCCCCEEEEEECCCC
GFDPEEINRLFRPFSRLHAAEQFPGTGVGLATVARVIRRHGGRTWAEGAVDRGATFFFTL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEE
NETPLPVVVPPQPEESA
CCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]