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The map label for this gene is cobJQ [H]

Identifier: 308513333

GI number: 308513333

Start: 3284732

End: 3287125

Strand: Reverse

Name: cobJQ [H]

Synonym: NA

Alternate gene names: 308513333

Gene position: 3287125-3284732 (Counterclockwise)

Preceding gene: 39998084

Following gene: 39998082

Centisome position: 86.18

GC content: 65.71

Gene sequence:

>2394_bases
GTGATGTCCATACTCTACGTCGTCGGGATCGGTCCCGGCGACCTCGACCATATGACGTTCCACGCCACCGAAGCCATCGA
GCGGGCCCAGGTGGTGGTAGGCTACAAGACCTACCTGGGGTTCATCGAGCCCCTGCTTGACGGCAAGGAGGTTGTCTCCT
CGGGGATGATGAAGGAGGTTGACCGCTGCCGCGAGGCCCTGGATGCCGCTGCGGCGGGCAAAACCGTGGCGCTGGTCTCC
AGCGGCGACGCGGGGGTCTACGGCATGGCTGGGCTGGCCATGGAGCTTGCGGCCACGATGACAGCCCCCCCCGAGATCGT
GGTGGTGCCGGGAGTGTCGGCGGTGCAGGCGGCTGCTTCCGTTCTCGGCGCGCCGCTGATGCACGATTTTGCAGTCATCT
CCCTGTCGGATCTCCTGACCCCCTGGGATGTCATCGAGCGCCGGCTCGTGGCCGCCGCGGCCGCCGACTTCGTGGTTGCC
CTCTACAACCCCCGGAGCAAGGGGCGGGTCACGCAGATCGAGGAGGCCCGGACGATCCTGCTGGCGGCCCGCGCCTCCAC
CACGCCGGTCGGCATTGTCCGCAACGCCTGCCGGGAAGGGGAGACCCGGGTTGTGACCACCCTGGCGTCAATGCTCGACC
ATGAGATCGACATGTTTTCCCTGGTCATCATCGGCAACTCCGCCACCTTCGTGGATCGGGAGGGCCGGATGGTTACGCCG
CGGGGCTATAAGGCCGGGCCCGGGGCCGAGGGACCAGGGGCCGGGGAACAGCAAAAGAACTCAGTCGATGGACAGTTGTC
CGATTCTCCGTCTCGGATTTTGAATTCCCGGTCCCCGATTCCCGATCCCGGGTCCCCGGCTTCACATTCCCGGTCCCTGA
TGGTCGTCGGCACTGCCTCCGACGTGGGGAAGTCGGTTGTTACGGCCGGTATCTGCCGCATCATGAAAAACCGGGGCTTC
TCCGTGGCGCCGTTCAAGTCCCAGAACATGGCCCTCAACTCGGCCGTTACACCGGAAGGCGGAGAGATCGGCCGGGCCCA
GGCGGTGCAGGCGGAGGCCTGCGGCATCGAGCCCCACACCGACATGAACCCCATACTCCTTAAGCCGACCACCGACTGCG
GCAGCCAGGTGATCGTCCAGGGGGCGGTGGTGGGGAACATGACGGTTCGGGAATACAACGACTACAAGCCCACCGCCTTC
GAGAAGGCGCGCGAGAGCTTCGGGCGACTCGCCGCCGGCCATGACCTGGTGGTGATCGAGGGGGCCGGCAGCATCGCCGA
GATCAACCTGAAGCGCCATGACATCGCCAACCTGAAGGTGGCGGAGATGGCTGGCTGCAAGGCCGTGCTGGTGGCGGACA
TAGACCGTGGCGGGGTGTTCGCCCAGATCGTCGGTACCCTGGAGCTTCTGGAGCCCCATGAGCGGGAGCGGATCGCCGGC
GTGATCATCAACAAGTTCCGGGGGGATGCATCGCTCCTGGCGCCGGGCATCGGTTTCATTGAGGAGCGCACCGGTGTGCC
TGTTTTGGGAGTGGTGCCCTGTTTCAGCGGCTTCCGTCTTCCCGAGGAAGACAGCGTGGCCCTGGAAAAGCGGAAAGCGG
AAAACGGCGATCGGGGCCCGGCGGCAGATCGGCTGAACATCGGCGTGGTGAAGCTGTCACGCATCTCCAACTACACCGAT
TTCGACGCCCTGGAGGCGGAGCCGGATGTCCAGCTCACGTATGTGGAGGGTGAAGAGCAGCTGCGAGGACTCGATCTCCT
CGTTATCCCGGGGAGCAAGGCGACCACCACCGATCTCTTCTTTCTCATGGAGCGGGGATTGTTTCCGGCGATACAATCGT
TCACCGGCCCCATCGTGGGCATCTGCGGCGGGTACCAGATGCTCGGCAAGCGGGTTGCCGATCCCCATGCAGTGGAGTCC
GACATCCGCGAGGCCGAGGGGCTCGGGCTGCTGGACGTGGTCACGGTGATGCTGGAGCAGAAATCCACCCATCGGGCCGC
GGCCGAGCTGCTGCCGTCGGGGTTCCTGGTGGCGCCCCGCTGCCGGGGGGGGCTGGCCGGCTATGAAATCCACATGGGAG
AGACGATCCTCGGCCCGTCGGTCCGTCCCTTTGCCCGGATCACGAGCCGTTCCGGCGCGCCGGTGGAGGTGCTGGACGGC
GCCGTCTCCAGTGACGGCCGCGTGTTCGGCACCTACCTGCACGGTATCTTCGACAATGCCGTGTTTCGCACCTCGCTCCT
CAACCGGCTGCGCAAGGCGAAGGGGTTGGCGGAGCGCCGGCCCGGACAGGGGGGCGACGATCCCTTCAACCTGCTTGCCG
CGCACCTGGAGAAGCATCTGAACATTGATCGCATGCTGGAACTCTGCGGCCTCGGCGGGATGTTGCCGGAGTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:
NA

Sequences:

>Translated_797_residues
MMSILYVVGIGPGDLDHMTFHATEAIERAQVVVGYKTYLGFIEPLLDGKEVVSSGMMKEVDRCREALDAAAAGKTVALVS
SGDAGVYGMAGLAMELAATMTAPPEIVVVPGVSAVQAAASVLGAPLMHDFAVISLSDLLTPWDVIERRLVAAAAADFVVA
LYNPRSKGRVTQIEEARTILLAARASTTPVGIVRNACREGETRVVTTLASMLDHEIDMFSLVIIGNSATFVDREGRMVTP
RGYKAGPGAEGPGAGEQQKNSVDGQLSDSPSRILNSRSPIPDPGSPASHSRSLMVVGTASDVGKSVVTAGICRIMKNRGF
SVAPFKSQNMALNSAVTPEGGEIGRAQAVQAEACGIEPHTDMNPILLKPTTDCGSQVIVQGAVVGNMTVREYNDYKPTAF
EKARESFGRLAAGHDLVVIEGAGSIAEINLKRHDIANLKVAEMAGCKAVLVADIDRGGVFAQIVGTLELLEPHERERIAG
VIINKFRGDASLLAPGIGFIEERTGVPVLGVVPCFSGFRLPEEDSVALEKRKAENGDRGPAADRLNIGVVKLSRISNYTD
FDALEAEPDVQLTYVEGEEQLRGLDLLVIPGSKATTTDLFFLMERGLFPAIQSFTGPIVGICGGYQMLGKRVADPHAVES
DIREAEGLGLLDVVTVMLEQKSTHRAAAELLPSGFLVAPRCRGGLAGYEIHMGETILGPSVRPFARITSRSGAPVEVLDG
AVSSDGRVFGTYLHGIFDNAVFRTSLLNRLRKAKGLAERRPGQGGDDPFNLLAAHLEKHLNIDRMLELCGLGGMLPE
>Mature_797_residues
MMSILYVVGIGPGDLDHMTFHATEAIERAQVVVGYKTYLGFIEPLLDGKEVVSSGMMKEVDRCREALDAAAAGKTVALVS
SGDAGVYGMAGLAMELAATMTAPPEIVVVPGVSAVQAAASVLGAPLMHDFAVISLSDLLTPWDVIERRLVAAAAADFVVA
LYNPRSKGRVTQIEEARTILLAARASTTPVGIVRNACREGETRVVTTLASMLDHEIDMFSLVIIGNSATFVDREGRMVTP
RGYKAGPGAEGPGAGEQQKNSVDGQLSDSPSRILNSRSPIPDPGSPASHSRSLMVVGTASDVGKSVVTAGICRIMKNRGF
SVAPFKSQNMALNSAVTPEGGEIGRAQAVQAEACGIEPHTDMNPILLKPTTDCGSQVIVQGAVVGNMTVREYNDYKPTAF
EKARESFGRLAAGHDLVVIEGAGSIAEINLKRHDIANLKVAEMAGCKAVLVADIDRGGVFAQIVGTLELLEPHERERIAG
VIINKFRGDASLLAPGIGFIEERTGVPVLGVVPCFSGFRLPEEDSVALEKRKAENGDRGPAADRLNIGVVKLSRISNYTD
FDALEAEPDVQLTYVEGEEQLRGLDLLVIPGSKATTTDLFFLMERGLFPAIQSFTGPIVGICGGYQMLGKRVADPHAVES
DIREAEGLGLLDVVTVMLEQKSTHRAAAELLPSGFLVAPRCRGGLAGYEIHMGETILGPSVRPFARITSRSGAPVEVLDG
AVSSDGRVFGTYLHGIFDNAVFRTSLLNRLRKAKGLAERRPGQGGDDPFNLLAAHLEKHLNIDRMLELCGLGGMLPE

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: 6.3.5.10

Molecular weight: Translated: 84517; Mature: 84517

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSILYVVGIGPGDLDHMTFHATEAIERAQVVVGYKTYLGFIEPLLDGKEVVSSGMMKEV
CCEEEEEEECCCCCCCCEEEHHHHHHHHHHEEEEHHHHHHHHHHHCCCHHHHHHHHHHHH
DRCREALDAAAAGKTVALVSSGDAGVYGMAGLAMELAATMTAPPEIVVVPGVSAVQAAAS
HHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
VLGAPLMHDFAVISLSDLLTPWDVIERRLVAAAAADFVVALYNPRSKGRVTQIEEARTIL
HHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHEEEE
LAARASTTPVGIVRNACREGETRVVTTLASMLDHEIDMFSLVIIGNSATFVDREGRMVTP
EEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCEECC
RGYKAGPGAEGPGAGEQQKNSVDGQLSDSPSRILNSRSPIPDPGSPASHSRSLMVVGTAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECCH
DVGKSVVTAGICRIMKNRGFSVAPFKSQNMALNSAVTPEGGEIGRAQAVQAEACGIEPHT
HHHHHHHHHHHHHHHHCCCCEECCCCCCCEEECCCCCCCCCCCCCHHHEEHHHCCCCCCC
DMNPILLKPTTDCGSQVIVQGAVVGNMTVREYNDYKPTAFEKARESFGRLAAGHDLVVIE
CCCCEEEECCCCCCCCEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEE
GAGSIAEINLKRHDIANLKVAEMAGCKAVLVADIDRGGVFAQIVGTLELLEPHERERIAG
CCCCEEEEEECCCCCCCEEHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHH
VIINKFRGDASLLAPGIGFIEERTGVPVLGVVPCFSGFRLPEEDSVALEKRKAENGDRGP
HHHHHHCCCHHHHCCCCCHHHHCCCCCEEEHHHCCCCCCCCCCCCHHHHHHHCCCCCCCC
AADRLNIGVVKLSRISNYTDFDALEAEPDVQLTYVEGEEQLRGLDLLVIPGSKATTTDLF
CCCCEEEEEEEEEHHCCCCCCCCCCCCCCEEEEEECCHHHHCCCEEEEECCCCCCHHHHH
FLMERGLFPAIQSFTGPIVGICGGYQMLGKRVADPHAVESDIREAEGLGLLDVVTVMLEQ
HHHHHCCHHHHHHHCCCEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHC
KSTHRAAAELLPSGFLVAPRCRGGLAGYEIHMGETILGPSVRPFARITSRSGAPVEVLDG
CHHHHHHHHHCCCCCEECCCCCCCCCCEEEECCCEECCCCCCHHHHHHCCCCCCHHHHCC
AVSSDGRVFGTYLHGIFDNAVFRTSLLNRLRKAKGLAERRPGQGGDDPFNLLAAHLEKHL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHC
NIDRMLELCGLGGMLPE
CHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMSILYVVGIGPGDLDHMTFHATEAIERAQVVVGYKTYLGFIEPLLDGKEVVSSGMMKEV
CCEEEEEEECCCCCCCCEEEHHHHHHHHHHEEEEHHHHHHHHHHHCCCHHHHHHHHHHHH
DRCREALDAAAAGKTVALVSSGDAGVYGMAGLAMELAATMTAPPEIVVVPGVSAVQAAAS
HHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHH
VLGAPLMHDFAVISLSDLLTPWDVIERRLVAAAAADFVVALYNPRSKGRVTQIEEARTIL
HHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHEEEE
LAARASTTPVGIVRNACREGETRVVTTLASMLDHEIDMFSLVIIGNSATFVDREGRMVTP
EEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCEECC
RGYKAGPGAEGPGAGEQQKNSVDGQLSDSPSRILNSRSPIPDPGSPASHSRSLMVVGTAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECCH
DVGKSVVTAGICRIMKNRGFSVAPFKSQNMALNSAVTPEGGEIGRAQAVQAEACGIEPHT
HHHHHHHHHHHHHHHHCCCCEECCCCCCCEEECCCCCCCCCCCCCHHHEEHHHCCCCCCC
DMNPILLKPTTDCGSQVIVQGAVVGNMTVREYNDYKPTAFEKARESFGRLAAGHDLVVIE
CCCCEEEECCCCCCCCEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEE
GAGSIAEINLKRHDIANLKVAEMAGCKAVLVADIDRGGVFAQIVGTLELLEPHERERIAG
CCCCEEEEEECCCCCCCEEHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHH
VIINKFRGDASLLAPGIGFIEERTGVPVLGVVPCFSGFRLPEEDSVALEKRKAENGDRGP
HHHHHHCCCHHHHCCCCCHHHHCCCCCEEEHHHCCCCCCCCCCCCHHHHHHHCCCCCCCC
AADRLNIGVVKLSRISNYTDFDALEAEPDVQLTYVEGEEQLRGLDLLVIPGSKATTTDLF
CCCCEEEEEEEEEHHCCCCCCCCCCCCCCEEEEEECCHHHHCCCEEEEECCCCCCHHHHH
FLMERGLFPAIQSFTGPIVGICGGYQMLGKRVADPHAVESDIREAEGLGLLDVVTVMLEQ
HHHHHCCHHHHHHHCCCEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHC
KSTHRAAAELLPSGFLVAPRCRGGLAGYEIHMGETILGPSVRPFARITSRSGAPVEVLDG
CHHHHHHHHHCCCCCEECCCCCCCCCCEEEECCCEECCCCCCHHHHHHCCCCCCHHHHCC
AVSSDGRVFGTYLHGIFDNAVFRTSLLNRLRKAKGLAERRPGQGGDDPFNLLAAHLEKHL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHC
NIDRMLELCGLGGMLPE
CHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA