Click here to switch to the map view.

The map label for this gene is int [H]

Identifier: 39997562

GI number: 39997562

Start: 2705340

End: 2706713

Strand: Reverse

Name: int [H]

Synonym: GSU2467

Alternate gene names: 39997562

Gene position: 2706713-2705340 (Counterclockwise)

Preceding gene: 39997566

Following gene: 39997559

Centisome position: 70.97

GC content: 55.9

Gene sequence:

>1374_bases
ATGATTTTACTGCCGCACCATCTGTTCAGGCAATACCGTTCTTTTTACAACAACTGCGGAATCGCGGTCGCTGATTTTGC
CGACTATCTGAAATGGCTGCGCTACTTTCTCGATTTCTGTGAAAAGTATCATGTTACGGGAAGCGAGCCGGAGAGAATCG
ATCTCTTCCTGAACAAGTTGCAGCAAAAAGGACAGTCTGAGCAGAAGCGGCAGCAGGCCAGTCAGGCGGTATCTTTGTAT
TTCGTCATGCTGAAGGGTGGCGCCAGTGACACGTTGCCGGTGTCCTCAGCCCCGTCCGCACAACCGATGGCGCAGCAGTC
GGAAGGTTCGGCTGACGTGCCGCCCGACTCTCCTCCTGTTCCCCCGCGGCACTCTTTCTATAACGTCGCTGGCTACCAGG
AAAAATCCGACTCTCCTGAATGGGATGAGGTTATGGCGAAGCTGGCAGCGGAAATCAAGGTCAGGCATTATTCCAGGAAA
ACATTGCAGACCTACGCCAAGTGGTGCCGTCAATTCCAGCGCTTTTTGAAGAACAAGCCTCCAGTGGAGCTGACAACCGC
GGATGTGAAAGAGTATCTAACCTGGCTGGCGGTGAAGTGTAATGTGGCCGCCTCTACGCAAAATCAGGCGTTCAACTCGC
TGCTGTTTCTGTTCCGCCATGCCCTGAAGCGGGATTTCGGCGAACTGAGGGACGTGCCGCGCGCCAAGAAGTCGCTCTAT
GTGCCGGTGGTGCTGTCCCGTGCAGAGATCGACGCTATCCTTGCCCACCTCTATCACCCCCATGGCCTGATCGTGAAACT
CCTGTTCGGCTGCGGGCTGCGGCTGTTCGAGTGTCTGCAGCTGCGGGTTCGGGATTTCAACTTCGATGCGGGTATCCTTA
CGGTCCACGGCAAGGGGAAGAAGGATCGGACTCTGCCGCTGCCGGAGTCTATCCTGAATGATTTGCAGCGGCAGATGCGG
CGGGTGAAGGAGTTGCATGAAAAGGATCTGGAGCAGGGGTATGACGGTGTGTTCCTCGATGATGCTATGGAGAAAAAATA
CCCCAAAGCGCCGAAGGAGCTGATTCATCAATGGTTCTTTCCGCAAAAGGATCTGACGCCGGTGGAGGCGAACGGGCAGC
TCAGGCGGGCGCATGTCCATGAGTCACTCTTGCAGAAGGCGCTCTACCTGGCCGTCCGCAAGGCAAAGATCCCCAAGCGG
GTTACGGCCCATACCTTCCGCCACTCCTACGCGACGCACCTGCTGCAGGCCAATTACGATATCCGCACCATCCAGACCAA
GCTGGGGCATGCCAGCCTGAAAACGACAATGATTTATACCCATTGTGTTCCGGTCAGGACCGTGAAGGAGGCGCGAAGCC
CGCTGGATTTCTGA

Upstream 100 bases:

>100_bases
AGGGTCAAGCGTGTTTTCATTGGTCACCCGCATCGAAAATATGTCGCCAACTATACGCATTCTTTGATAGAACTTAAATT
AAAAATTCTGAGGAATTGTG

Downstream 100 bases:

>100_bases
TTGCGCGTGGGCGGCCTAACTCAAACCCTTCCTGATCTGGTACAGCTCCTCCAGATCCAGCTCGTTCAGCTCGAAGTACT
CCCGCTCCAGTTCCTCAACG

Product: bifunctional hypothetical protein/integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MILLPHHLFRQYRSFYNNCGIAVADFADYLKWLRYFLDFCEKYHVTGSEPERIDLFLNKLQQKGQSEQKRQQASQAVSLY
FVMLKGGASDTLPVSSAPSAQPMAQQSEGSADVPPDSPPVPPRHSFYNVAGYQEKSDSPEWDEVMAKLAAEIKVRHYSRK
TLQTYAKWCRQFQRFLKNKPPVELTTADVKEYLTWLAVKCNVAASTQNQAFNSLLFLFRHALKRDFGELRDVPRAKKSLY
VPVVLSRAEIDAILAHLYHPHGLIVKLLFGCGLRLFECLQLRVRDFNFDAGILTVHGKGKKDRTLPLPESILNDLQRQMR
RVKELHEKDLEQGYDGVFLDDAMEKKYPKAPKELIHQWFFPQKDLTPVEANGQLRRAHVHESLLQKALYLAVRKAKIPKR
VTAHTFRHSYATHLLQANYDIRTIQTKLGHASLKTTMIYTHCVPVRTVKEARSPLDF

Sequences:

>Translated_457_residues
MILLPHHLFRQYRSFYNNCGIAVADFADYLKWLRYFLDFCEKYHVTGSEPERIDLFLNKLQQKGQSEQKRQQASQAVSLY
FVMLKGGASDTLPVSSAPSAQPMAQQSEGSADVPPDSPPVPPRHSFYNVAGYQEKSDSPEWDEVMAKLAAEIKVRHYSRK
TLQTYAKWCRQFQRFLKNKPPVELTTADVKEYLTWLAVKCNVAASTQNQAFNSLLFLFRHALKRDFGELRDVPRAKKSLY
VPVVLSRAEIDAILAHLYHPHGLIVKLLFGCGLRLFECLQLRVRDFNFDAGILTVHGKGKKDRTLPLPESILNDLQRQMR
RVKELHEKDLEQGYDGVFLDDAMEKKYPKAPKELIHQWFFPQKDLTPVEANGQLRRAHVHESLLQKALYLAVRKAKIPKR
VTAHTFRHSYATHLLQANYDIRTIQTKLGHASLKTTMIYTHCVPVRTVKEARSPLDF
>Mature_457_residues
MILLPHHLFRQYRSFYNNCGIAVADFADYLKWLRYFLDFCEKYHVTGSEPERIDLFLNKLQQKGQSEQKRQQASQAVSLY
FVMLKGGASDTLPVSSAPSAQPMAQQSEGSADVPPDSPPVPPRHSFYNVAGYQEKSDSPEWDEVMAKLAAEIKVRHYSRK
TLQTYAKWCRQFQRFLKNKPPVELTTADVKEYLTWLAVKCNVAASTQNQAFNSLLFLFRHALKRDFGELRDVPRAKKSLY
VPVVLSRAEIDAILAHLYHPHGLIVKLLFGCGLRLFECLQLRVRDFNFDAGILTVHGKGKKDRTLPLPESILNDLQRQMR
RVKELHEKDLEQGYDGVFLDDAMEKKYPKAPKELIHQWFFPQKDLTPVEANGQLRRAHVHESLLQKALYLAVRKAKIPKR
VTAHTFRHSYATHLLQANYDIRTIQTKLGHASLKTTMIYTHCVPVRTVKEARSPLDF

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 52662; Mature: 52662

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLPHHLFRQYRSFYNNCGIAVADFADYLKWLRYFLDFCEKYHVTGSEPERIDLFLNKL
CEECCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
QQKGQSEQKRQQASQAVSLYFVMLKGGASDTLPVSSAPSAQPMAQQSEGSADVPPDSPPV
HHCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCC
PPRHSFYNVAGYQEKSDSPEWDEVMAKLAAEIKVRHYSRKTLQTYAKWCRQFQRFLKNKP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVELTTADVKEYLTWLAVKCNVAASTQNQAFNSLLFLFRHALKRDFGELRDVPRAKKSLY
CCEEEHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEE
VPVVLSRAEIDAILAHLYHPHGLIVKLLFGCGLRLFECLQLRVRDFNFDAGILTVHGKGK
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEECCCC
KDRTLPLPESILNDLQRQMRRVKELHEKDLEQGYDGVFLDDAMEKKYPKAPKELIHQWFF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHCCCCCHHHHHHHHCC
PQKDLTPVEANGQLRRAHVHESLLQKALYLAVRKAKIPKRVTAHTFRHSYATHLLQANYD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
IRTIQTKLGHASLKTTMIYTHCVPVRTVKEARSPLDF
HHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MILLPHHLFRQYRSFYNNCGIAVADFADYLKWLRYFLDFCEKYHVTGSEPERIDLFLNKL
CEECCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
QQKGQSEQKRQQASQAVSLYFVMLKGGASDTLPVSSAPSAQPMAQQSEGSADVPPDSPPV
HHCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCC
PPRHSFYNVAGYQEKSDSPEWDEVMAKLAAEIKVRHYSRKTLQTYAKWCRQFQRFLKNKP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVELTTADVKEYLTWLAVKCNVAASTQNQAFNSLLFLFRHALKRDFGELRDVPRAKKSLY
CCEEEHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEE
VPVVLSRAEIDAILAHLYHPHGLIVKLLFGCGLRLFECLQLRVRDFNFDAGILTVHGKGK
HHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEECCCC
KDRTLPLPESILNDLQRQMRRVKELHEKDLEQGYDGVFLDDAMEKKYPKAPKELIHQWFF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHCCCCCHHHHHHHHCC
PQKDLTPVEANGQLRRAHVHESLLQKALYLAVRKAKIPKRVTAHTFRHSYATHLLQANYD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
IRTIQTKLGHASLKTTMIYTHCVPVRTVKEARSPLDF
HHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]